About: PDX-1 is required for pancreatic outgrowth and differentiation of the rostral duodenum

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About: PDX-1 is required for pancreatic outgrowth and differentiation of the rostral duodenum Goto Sponge NotDistinct Permalink

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scientific article (publication date: March 1996)

Attributes	Values
rdf:type	Item
description	artículu científicu espublizáu en 1996 (ast) наукова стаття, опублікована в березні 1996 (uk) 1996 թվականի մարտին հրատարակված գիտական հոդված (hy) 1996 թուականի Մարտին հրատարակուած գիտական յօդուած (hyw) مقالة علمية (نشرت في مارس 1996) (ar) wetenschappelijk artikel (gepubliceerd in 1996-03) (nl) scientific article (publication date: March 1996) (en) article scientifique publié en 1996 (fr) im März 1996 veröffentlichter wissenschaftlicher Artikel (de)
publication date	wds:Q29618151-011A62E9-5445-4E62-9827-56B056C57D2E
publication date	1996-03-01 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q29618151-30CDE1CF-3B8B-421F-9DD2-47A18AFA1B5B
language of work or name	English
author name string	wds:Q29618151-02C8DB1B-1FC5-458D-9699-A84FD5675AA9 wds:Q29618151-10B5CA85-D6D8-4C14-BFAF-2E71F5281E85 wds:Q29618151-317A3374-00F2-4779-9F32-BD93A5E56F9D wds:Q29618151-438C86F2-67AD-48DC-9A37-ACF6761F1841 wds:Q29618151-4D7F8328-7615-45B9-8D5A-F79F868C4685 wds:Q29618151-791D5D2A-BF15-4CD3-8A42-357CFF1C53F6 wds:Q29618151-8A948A3E-03F2-4699-B7CF-CAD38E25D4FF wds:Q29618151-E85B3369-7EE3-4351-B91B-608D0A8E1B7F
OpenCitations bibliographic resource ID	wds:Q29618151-3196254B-EB1C-46BF-AEB0-548493C57009
OpenCitations bibliographic resource ID	https://w3id.org/oc/corpus/br/1986456
author name string	Ray M Jetton TL Magnuson MA Hogan BL Labosky PA Wright CV Stein RW Offield MF
OpenCitations bibliographic resource ID	1986456
rdfs:label	PDX-1 is required for pancreatic outgrowth and differentiation of the rostral duodenum (en) PDX-1 is required for pancreatic outgrowth and differentiation of the rostral duodenum (ast)
skos:prefLabel	PDX-1 is required for pancreatic outgrowth and differentiation of the rostral duodenum (en) PDX-1 is required for pancreatic outgrowth and differentiation of the rostral duodenum (ast)
name	PDX-1 is required for pancreatic outgrowth and differentiation of the rostral duodenum (en) PDX-1 is required for pancreatic outgrowth and differentiation of the rostral duodenum (ast)
title	wds:Q29618151-F5CCADCE-E7A0-4808-AFCF-72809E85369C
title	PDX-1 is required for pancreatic outgrowth and differentiation of the rostral duodenum (en)
page(s)	wds:Q29618151-10D92F85-461F-4A9E-965E-48561AC322BC
page(s)	983-95
instance of	wds:Q29618151-015B062D-2B93-4F0D-9F7E-CE0ABE13DA93
instance of	scholarly article
PubMed ID	wds:Q29618151-E7369217-27FF-4C64-B43F-2D2089EE94F3
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/8631275
PubMed ID	8631275
published in	wds:Q29618151-4BC87035-F131-4670-8B87-16FEBA77BA81
published in	Development
issue	wds:Q29618151-51884B08-602C-44C2-88F1-D6F8F11A6787
volume	wds:Q29618151-F08E5F02-AD78-43AE-B4CE-815BDA68AAC7
issue	3
volume	122
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q29618151
is cites work of	Features of the ancestral bilaterian inferred from Platynereis dumerilii ParaHox genes Histone deacetylase (HDAC) inhibition as a novel treatment for diabetes mellitus Lineage determinants in early endocrine development TALE-family homeodomain proteins regulate endodermal sonic hedgehog expression and pattern the anterior endoderm The role of Cdx genes in the mammalian gut. FGF4 and retinoic acid direct differentiation of hESCs into PDX1-expressing foregut endoderm in a time- and concentration-dependent manner Homeobox genes in gut development Bipotential mouse embryonic liver (BMEL) cells spontaneously express Pdx1 and Ngn3 but do not undergo further pancreatic differentiation upon Hes1 down-regulation LIM homeodomain transcription factor Isl1 directs normal pyloric development by targeting Gata3 The stromal cell-derived factor-1alpha/CXCR4 ligand-receptor axis is critical for progenitor survival and migration in the pancreas Recessive mutations in a distal PTF1A enhancer cause isolated pancreatic agenesis. Targeting pancreatic islets with phage display assisted by laser pressure catapult microdissection Fetal PGC-1α overexpression programs adult pancreatic β-cell dysfunction Vitamin A in reproduction and development Beyond Hox: the role of ParaHox genes in normal and malignant hematopoiesis Pdx-1 links histone H3-Lys-4 methylation to RNA polymerase II elongation during activation of insulin transcription PDX:PBX complexes are required for normal proliferation of pancreatic cells during development Impaired insulin secretion in vivo but enhanced insulin secretion from isolated islets in pancreatic beta cell-specific vascular endothelial growth factor-A knock-out mice. Dedifferentiation, transdifferentiation and reprogramming: three routes to regeneration Little evidence of transdifferentiation of bone marrow-derived cells into pancreatic beta cells Mouse models of pancreatic cancer Islet α-, β-, and δ-cell development is controlled by the Ldb1 coregulator, acting primarily with the islet-1 transcription factor. MafA and MafB activity in pancreatic β cells Vascular instruction of pancreas development Pancreatic ductal morphogenesis and the Pdx1 homeodomain transcription factor. Functional characterization of the transactivation properties of the PDX-1 homeodomain protein Glucagon is essential for alpha cell transdifferentiation and beta cell neogenesis. Embryonic endocrine pancreas and mature beta cells acquire alpha and PP cell phenotypes upon Arx misexpression. Consequences of a compromised intrauterine environment on islet function Pdx1 maintains β cell identity and function by repressing an α cell program Stem cell therapy for type 1 diabetes mellitus The homeodomain of PDX-1 mediates multiple protein-protein interactions in the formation of a transcriptional activation complex on the insulin promoter Enriched human pancreatic ductal cultures obtained from selective death of acinar cells express pancreatic and duodenal homeobox gene-1 age-dependently Pcif1 modulates Pdx1 protein stability and pancreatic β cell function and survival in mice RB regulates pancreas development by stabilizing Pdx1 Targeted deletion of a cis-regulatory region reveals differential gene dosage requirements for Pdx1 in foregut organ differentiation and pancreas formation Gene array identification of Ipf1/Pdx1-/- regulated genes in pancreatic progenitor cells Cdk4 regulates recruitment of quiescent beta-cells and ductal epithelial progenitors to reconstitute beta-cell mass A novel hypomorphic PDX1 mutation responsible for permanent neonatal diabetes with subclinical exocrine deficiency Ptf1a binds to and activates area III, a highly conserved region of the Pdx1 promoter that mediates early pancreas-wide Pdx1 expression Reduction of Ptf1a gene dosage causes pancreatic hypoplasia and diabetes in mice Differential ability of Ptf1a and Ptf1a-VP16 to convert stomach, duodenum and liver to pancreas Graded levels of Ptf1a differentially regulate endocrine and exocrine fates in the developing pancreas. Key events of pancreas formation are triggered in gut endoderm by ectopic expression of pancreatic regulatory genes Mammalian hepatocyte differentiation requires the transcription factor HNF-4alpha.

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