About: The myeloma-associated oncogene fibroblast growth factor receptor 3 is transforming in hematopoietic cells

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rdf:type	Item
description	artículu científicu espublizáu en 2001 (ast) vědecký článek publikovaný v roce 2001 (cs) наукова стаття, опублікована у квітні 2001 (uk) 2001 թուականի Ապրիլին հրատարակուած գիտական յօդուած (hyw) 2001 թվականի ապրիլին հրատարակված գիտական հոդված (hy) vedecký článok (publikovaný 2001/04/15) (sk) مقالة علمية (نشرت في 15-4-2001) (ar) wetenschappelijk artikel (gepubliceerd op 2001/04/15) (nl) im April 2001 veröffentlichter wissenschaftlicher Artikel (de) article scientifique publié en 2001 (fr) scientific journal article (en)
publication date	wds:Q28678602-AB7155F5-A09E-4A88-8CCA-2EBDF4F82651
publication date	2001-04-15 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q28678602-2FCD8AAD-DE6C-4E27-8E83-4D0AA34D6E00
language of work or name	English
cites work	wds:Q28678602-12648186-F293-468E-A545-DEBFA3474891
cites work	Fibroblast growth factor receptor 3 is a negative regulator of bone growth
author name string	wds:Q28678602-2248A766-B8E9-47E9-AE32-DE9A110002F3 wds:Q28678602-2A016381-91EE-407E-AD1B-AB37FFF2BA8F wds:Q28678602-8204CA3B-FFF1-47ED-8D2B-D52FC96FBC9C wds:Q28678602-AE7635CE-B3A2-49DB-BD16-C135D1FF2436 wds:Q28678602-AF89332A-AA75-41C3-B290-48EF4CF2ED03 wds:Q28678602-B4891095-3241-4F31-8725-CD1BF2104E15 wds:Q28678602-B57F9A93-E363-405E-A499-872D39FC4425 wds:Q28678602-D3BAA57D-9E98-4732-AFDF-C1E91EA927B3 wds:Q28678602-ECEF442B-B486-4706-8EA7-FC71AFB8CDD6
author name string	Z. Li P. L. Bergsagel R. G. Hawley B. Patterson Y. X. Zhu A. K. Stewart E. E. Plowright M. Chesi T. S. Hawley
rdfs:label	The myeloma-associated oncogene fibroblast growth factor receptor 3 is transforming in hematopoietic cells (en) The myeloma-associated oncogene fibroblast growth factor receptor 3 is transforming in hematopoietic cells (nl) The myeloma-associated oncogene fibroblast growth factor receptor 3 is transforming in hematopoietic cells (ast)
skos:prefLabel	The myeloma-associated oncogene fibroblast growth factor receptor 3 is transforming in hematopoietic cells (en) The myeloma-associated oncogene fibroblast growth factor receptor 3 is transforming in hematopoietic cells (nl) The myeloma-associated oncogene fibroblast growth factor receptor 3 is transforming in hematopoietic cells (ast)
name	The myeloma-associated oncogene fibroblast growth factor receptor 3 is transforming in hematopoietic cells (en) The myeloma-associated oncogene fibroblast growth factor receptor 3 is transforming in hematopoietic cells (nl) The myeloma-associated oncogene fibroblast growth factor receptor 3 is transforming in hematopoietic cells (ast)
title	wds:Q28678602-0E16A565-EBD2-498C-A2FD-DB6B6B49A0EC
title	The myeloma-associated oncogene fibroblast growth factor receptor 3 is transforming in hematopoietic cells (en)
page(s)	wds:Q28678602-CDB9282D-C7EA-4997-8280-539CE7ADC7AA
page(s)	2413–2419
instance of	wds:Q28678602-26413ED6-4033-49F6-B016-FA1EEAD1548F
instance of	scholarly article
PubMed ID	wds:Q28678602-DA590CD1-C2A3-4A1B-9697-803FEBA91CAE
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/11290605
PubMed ID	11290605
published in	wds:Q28678602-0C58E9D0-2A9C-406B-858F-AB4AC9B937C4
published in	Blood
issue	wds:Q28678602-5BADB8A1-ECB3-4B10-B28B-1DC12821490E
volume	wds:Q28678602-2782E7BF-6E3A-4F1F-A70D-FBF6F587C867
issue	8
volume	97
DOI	wds:Q28678602-E23ACA26-87BB-4562-8468-0101FEDBF948
DOI	http://dx.doi.org/10.1182/BLOOD.V97.8.2413
DOI	10.1182/BLOOD.V97.8.2413
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q28678602
is cites work of	Cell responses to FGFR3 signalling: growth, differentiation and apoptosis Receptor tyrosine kinases in normal and malignant haematopoiesis Integrating cytogenetics and gene expression profiling in the molecular analysis of multiple myeloma Human combinatorial Fab library yielding specific and functional antibodies against the human fibroblast growth factor receptor 3. Fibroblast growth factor signalling: from development to cancer FGFR3 activates RSK2 to mediate hematopoietic transformation through tyrosine phosphorylation of RSK2 and activation of the MEK/ERK pathway Preclinical studies of fibroblast growth factor receptor 3 as a therapeutic target in multiple myeloma Targeting FGFR3 in multiple myeloma: inhibition of t(4;14)-positive cells by SU5402 and PD173074. Sixteen years and counting: the current understanding of fibroblast growth factor receptor 3 (FGFR3) signaling in skeletal dysplasias Activating mutations of the tyrosine kinase receptor FGFR3 are associated with benign skin tumors in mice and humans Small molecule tyrosine kinase inhibitors: clinical development of anticancer agents Constitutively activated FGFR3 mutants signal through PLCgamma-dependent and -independent pathways for hematopoietic transformation. The t(4;14) is associated with poor prognosis in myeloma patients undergoing autologous stem cell transplant Advances in immunotherapy of multiple myeloma: from the discovery of tumor-associated antigens to clinical trials. FGFR3 signaling induces a reversible senescence phenotype in chondrocytes similar to oncogene-induced premature senescence Fibroblast growth factors in cancer: therapeutic possibilities Fibroblast growth factor receptor 3 (FGFR3) associated with the CD20 antigen regulates the rituximab-induced proliferation inhibition in B-cell lymphoma cells Genomics in multiple myeloma Antibody-based targeting of FGFR3 in bladder carcinoma and t(4;14)-positive multiple myeloma in mice Molecular aspects of multiple myeloma Keratinocyte growth factor expression and activity in cancer: implications for use in patients with solid tumors Ectopic expression of wild-type FGFR3 cooperates with MYC to accelerate development of B-cell lineage neoplasms. FGFR3 has tumor suppressor properties in cells with epithelial phenotype Identification of FGFR4-activating mutations in human rhabdomyosarcomas that promote metastasis in xenotransplanted models Targeting the IGF-1R signaling and mechanisms for epigenetic gene silencing in human multiple myeloma The role of senescence and prosurvival signaling in controlling the oncogenic activity of FGFR2 mutants associated with cancer and birth defects Targeting RSK2 in human malignancies Targeting signalling pathways for the treatment of multiple myeloma Ten years and counting: so what do we know about t(4;14)(p16;q32) multiple myeloma. Crosstalk between KIT and FGFR3 Promotes Gastrointestinal Stromal Tumor Cell Growth and Drug Resistance Kinome-wide RNAi studies in human multiple myeloma identify vulnerable kinase targets, including a lymphoid-restricted kinase, GRK6. Quantitative expression profiling guided by common retroviral insertion sites reveals novel and cell type specific cancer genes in leukemia The t(4;14) translocation and FGFR3 overexpression in multiple myeloma: prognostic implications and current clinical strategies FGFR3 as a therapeutic target of the small molecule inhibitor PKC412 in hematopoietic malignancies Dimerization of FGFR3 t(4;14) translocation mutants Autocatalytic phosphorylation of FGFR3 t(4;14) translocation mutants

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