About: The p53-mdm-2 autoregulatory feedback loop

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scientific journal article

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rdf:type	Item
description	artículu científicu espublizáu en 1993 (ast) vědecký článek publikovaný v roce 1993 (cs) مقالة علمية (نشرت في يوليو 1993) (ar) 1993 թուականի Յուլիսին հրատարակուած գիտական յօդուած (hyw) 1993 թվականի հուլիսին հրատարակված գիտական հոդված (hy) наукова стаття, опублікована в липні 1993 (uk) vedecký článok (publikovaný 1993/07/01) (sk) scientific journal article (en) im Juli 1993 veröffentlichter wissenschaftlicher Artikel (de) wetenschappelijk artikel (gepubliceerd op 1993/07/01) (nl)
publication date	wds:Q28609811-9D767A11-830E-45A8-89AF-289A44A09D33
publication date	1993-07-01 00:00:00Z (xsd:dateTime)
author name string	wds:Q28609811-1934FD0E-5880-4353-A77C-9D2BBCAC08A9 wds:Q28609811-33505B1C-BC29-4A06-BB2A-10673AAAA284 wds:Q28609811-81E0822A-82BA-47E6-ADB5-A0723AAA3FCF wds:Q28609811-EACF20E6-4760-462D-B82D-61E2E759AD88
OpenCitations bibliographic resource ID	wds:Q28609811-19D813DE-EF73-4D55-9DF8-7448A4FB4BF5
OpenCitations bibliographic resource ID	https://w3id.org/oc/corpus/br/894704
author name string	X. Wu A. J. Levine D. Olson J. H. Bayle
OpenCitations bibliographic resource ID	894704
rdfs:label	The p53-mdm-2 autoregulatory feedback loop (en) The p53-mdm-2 autoregulatory feedback loop (nl) The p53-mdm-2 autoregulatory feedback loop (ast)
skos:prefLabel	The p53-mdm-2 autoregulatory feedback loop (en) The p53-mdm-2 autoregulatory feedback loop (nl) The p53-mdm-2 autoregulatory feedback loop (ast)
name	The p53-mdm-2 autoregulatory feedback loop (en) The p53-mdm-2 autoregulatory feedback loop (nl) The p53-mdm-2 autoregulatory feedback loop (ast)
title	wds:Q28609811-7CEF712A-5345-452E-9758-0B7AE1F83CFD
title	The p53-mdm-2 autoregulatory feedback loop (en)
page(s)	wds:Q28609811-ED13F5C2-F83E-452C-8A1D-EDB7DCE35DED
page(s)	1126–1132
instance of	wds:Q28609811-0A725120-8297-44C9-B392-DCDEB5B8B590
instance of	scholarly article
PubMed ID	wds:Q28609811-1443A2B1-C342-4CEC-9159-61066F1F2B6A
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/8319905
PubMed ID	8319905
published in	wds:Q28609811-30EA1D31-5BA4-4C90-8CCD-F0F032B5187C
published in	Genes & Development
issue	wds:Q28609811-318B6455-9F0D-416B-9C85-9F557BFCCB77
volume	wds:Q28609811-B6243619-37A0-44CB-AB8B-CF324E7EF356
issue	7A
volume	7
DOI	wds:Q28609811-43394F4E-E77B-4A3E-A9BB-2887B098769D
DOI	http://dx.doi.org/10.1101/GAD.7.7A.1126
DOI	10.1101/GAD.7.7A.1126
ResearchGate publication ID	wds:Q28609811-152B9D73-A328-47BA-BB85-889D30140132
ResearchGate publication ID	14879205
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q28609811
is cites work of	Hzf Determines cell survival upon genotoxic stress by modulating p53 transactivation Perturbation of cell cycle progression and cellular gene expression as a function of herpes simplex virus ICP0. Distinct p53, p53:LANA, and LANA complexes in Kaposi's Sarcoma--associated Herpesvirus Lymphomas Synergistic activation of transcription by CBP and p53 Complementary quantitative proteomics reveals that transcription factor AP-4 mediates E-box-dependent complex formation for transcriptional repression of HDM2 Regulation of p53 stability by Mdm2 DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2 DNA damage activates p53 through a phosphorylation-acetylation cascade Caspase-2-mediated cleavage of Mdm2 creates a p53-induced positive feedback loop Small-molecule inhibitors of the MDM2-p53 protein-protein interaction to reactivate p53 function: a novel approach for cancer therapy Ribosomal proteins and human diseases: pathogenesis, molecular mechanisms, and therapeutic implications Hydrophilic residues are crucial for ribosomal protein L11 (RPL11) interaction with zinc finger domain of MDM2 and p53 protein activation Nuclear accumulation of p53 following inhibition of transcription is not due to diminished levels of MDM2. The ability of p53 to activate downstream genes p21(WAF1/cip1) and MDM2, and cell cycle arrest following DNA damage is delayed and attenuated in scid cells deficient in the DNA-dependent protein kinase On the functional diversity of dynamical behaviour in genetic and metabolic feedback systems Epstein-Barr virus provides a survival factor to Burkitt's lymphomas P53 in bladder cancer: mechanism of action, prognostic value, and target for therapy A small molecule Inauhzin inhibits SIRT1 activity and suppresses tumour growth through activation of p53. Regulation of p53 stability and p53-dependent apoptosis by NADH quinone oxidoreductase 1 Human cytomegalovirus IE1-72 activates ataxia telangiectasia mutated kinase and a p53/p21-mediated growth arrest response Expression of Bcl-2 and p53 protein in resectable invasive ductal carcinoma of the pancreas: effects on clinical outcome and efficacy of adjuvant chemotherapy Inhibition of p53 transactivation function by the human T-cell lymphotropic virus type 1 Tax protein MDM2-HDAC1-mediated deacetylation of p53 is required for its degradation MDMX: a novel p53-binding protein with some functional properties of MDM2 ATM-dependent phosphorylation of Mdm2 on serine 395: role in p53 activation by DNA damage The E2F transcription factors: key regulators of cell proliferation Nucleo-cytoplasmic shuttling of the hdm2 oncoprotein regulates the levels of the p53 protein via a pathway used by the human immunodeficiency virus rev protein. Disruption of the ARF-Mdm2-p53 tumor suppressor pathway in Myc-induced lymphomagenesis Nucleocytoplasmic shuttling of p53 is essential for MDM2-mediated cytoplasmic degradation but not ubiquitination Nuclear export is required for degradation of endogenous p53 by MDM2 and human papillomavirus E6 p53-mediated regulation of proliferating cell nuclear antigen expression in cells exposed to ionizing radiation Reciprocal influence of the p53 and the hypoxic pathways Kinetics of p53 binding to promoter sites in vivo Preferential inactivation of the p53 tumor suppressor pathway and lack of EGFR amplification distinguish de novo high grade pediatric astrocytomas from de novo adult astrocytomas Targeting p53 for Novel Anticancer Therapy Reactivation of p53 by a specific MDM2 antagonist (MI-43) leads to p21-mediated cell cycle arrest and selective cell death in colon cancer Rescue of mutant p53 transcription function by ellipticine Enigma negatively regulates p53 through MDM2 and promotes tumor cell survival in mice Alterations in MDM2 expression in esophageal squamous cell carcinoma: relationship with p53 status Identification of FDA-approved drugs that computationally bind to MDM2 Physical interaction and functional antagonism between the RNA polymerase II elongation factor ELL and p53 Bax loss impairs Myc-induced apoptosis and circumvents the selection of p53 mutations during Myc-mediated lymphomagenesis Ribosomal protein L23 activates p53 by inhibiting MDM2 function in response to ribosomal perturbation but not to translation inhibition Prohibitin Induces the Transcriptional Activity of p53 and Is Exported from the Nucleus upon Apoptotic Signaling Regulation of transcription functions of the p53 tumor suppressor by the mdm-2 oncogene The mdm-2 gene is induced in response to UV light in a p53-dependent manner

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