About: Targeted disruption of the mouse apobec-1 gene abolishes apolipoprotein B mRNA editing and eliminates apolipoprotein B48

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scientific journal article

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description	artículu científicu espublizáu en 1996 (ast) vědecký článek publikovaný v roce 1996 (cs) 1996 թվականի ապրիլին հրատարակված գիտական հոդված (hy) наукова стаття, опублікована у квітні 1996 (uk) 1996 թուականի Ապրիլին հրատարակուած գիտական յօդուած (hyw) wetenschappelijk artikel (gepubliceerd op 1996/04/26) (nl) vedecký článok (publikovaný 1996/04/26) (sk) مقالة علمية (نشرت في 26-4-1996) (ar) article publié dans la revue scientifique Journal of Biological Chemistry (fr) scientific journal article (en) im April 1996 veröffentlichter wissenschaftlicher Artikel (de)
publication date	wds:Q28594252-97468A23-94EB-4CDF-B1CF-9B13628DF335
publication date	1996-04-26 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q28594252-AC461FAA-DED3-4F51-A81F-14F099F89D89
language of work or name	English
cites work	wds:Q28594252-03184E50-D185-49FC-9A48-D5385E17376B wds:Q28594252-0913F07E-9833-45C9-AD8F-78A120F89015 wds:Q28594252-0BC78655-440E-485E-BC0E-20111B593425 wds:Q28594252-123E62FF-96C3-42B7-9C77-ECEAFF6F5FA4 wds:Q28594252-133108A6-5C34-482E-93CD-C679B0E6D455 wds:Q28594252-2083A1CC-AB7B-4915-A5AF-B24A67ACAAD3 wds:Q28594252-5938A49F-EC79-4E9C-861C-3BF7A0644608 wds:Q28594252-6382661D-461F-47D5-947A-3A1EE22B7910 wds:Q28594252-6D6DC2E2-12F7-44A0-B603-3BC980604C85 wds:Q28594252-87CB2D2C-348A-4147-85BB-4A545EABD9BD wds:Q28594252-D1ACAC9B-B4E5-41C7-9B54-B65542C1E0BB wds:Q28594252-D22091EA-BCF8-49D1-ABDD-4C34F3A1FC73 wds:Q28594252-DF39DCD3-31AC-4A51-9A7B-DB09ED153F4C wds:Q28594252-E90F2A28-0C65-4E00-AC42-16ABC5C2F37D wds:Q28594252-F08E2EA3-0398-44FF-A8AE-53AC8EB5AECA wds:Q28594252-FE7D4279-6461-40C0-A621-54CEB1EA65F0
cites work	A novel form of tissue-specific RNA processing produces apolipoprotein-B48 in intestine Molecular cloning of an apolipoprotein B messenger RNA editing protein Apolipoprotein B-48 is the product of a messenger RNA with an organ-specific in-frame stop codon. Dimeric structure of a human apolipoprotein B mRNA editing protein and cloning and chromosomal localization of its gene Recent progress in understanding apolipoprotein B. Alternative mRNA splicing and differential promoter utilization determine tissue-specific expression of the apolipoprotein B mRNA-editing protein (Apobec1) gene in mice. Structure and evolution of Apobec1 and related nucleoside/nucleotide deaminases Mutagenesis of apobec-1, the catalytic subunit of the mammalian apolipoprotein B mRNA editing enzyme, reveals distinct domains that mediate cytosine nucleoside deaminase, RNA binding, and RNA editing activity Evolutionary origins of apoB mRNA editing: catalysis by a cytidine deaminase that has acquired a novel RNA-binding motif at its active site Apolipoprotein B mRNA-editing protein induces hepatocellular carcinoma and dysplasia in transgenic animals Knockout of the mouse apolipoprotein B gene results in embryonic lethality in homozygotes and protection against diet-induced hypercholesterolemia in heterozygotes Molecular cloning of a human small intestinal apolipoprotein B mRNA editing protein Mutagenesis of the human apolipoprotein B gene in a yeast artificial chromosome reveals the site of attachment for apolipoprotein(a) Transgenic mice expressing high levels of human apolipoprotein B develop severe atherosclerotic lesions in response to a high-fat diet. Apolipoprotein B mRNA editing is associated with UV crosslinking of proteins to the editing site Site-specific mutagenesis demonstrates that cysteine 4326 of apolipoprotein B is required for covalent linkage with apolipoprotein (a) in vivo Apolipoprotein B messenger RNA editing is developmentally regulated in pig small intestine: nucleotide comparison of apolipoprotein B editing regions in five species
author name string	wds:Q28594252-2788DD7F-4DFF-4D4A-8E32-314820E07AEF wds:Q28594252-2C485A49-4976-425C-8440-2B0CCC474925 wds:Q28594252-67D96845-141E-436C-BCF2-7157F10417BD wds:Q28594252-9FAEB83E-5C54-4CF4-8C6C-F91E7383C23A wds:Q28594252-A15CAC40-ACD3-48AF-A67F-34776FF2FE66 wds:Q28594252-A74FA565-8D38-4F77-B1E5-32498EB0C669 wds:Q28594252-B0CFACE3-FAB2-4EFF-B52F-8D892094F42F wds:Q28594252-F1B087F9-9B27-4761-91D7-D51386E28406
author name string	K. Hirano R. V. Farese C. Warburton E. Sande J. Ng L. M. Powell-Braxton N. O. Davidson S. G. Young
rdfs:label	Targeted disruption of the mouse apobec-1 gene abolishes apolipoprotein B mRNA editing and eliminates apolipoprotein B48 (en) Targeted disruption of the mouse apobec-1 gene abolishes apolipoprotein B mRNA editing and eliminates apolipoprotein B48 (nl) Targeted disruption of the mouse apobec-1 gene abolishes apolipoprotein B mRNA editing and eliminates apolipoprotein B48 (ast)
skos:prefLabel	Targeted disruption of the mouse apobec-1 gene abolishes apolipoprotein B mRNA editing and eliminates apolipoprotein B48 (en) Targeted disruption of the mouse apobec-1 gene abolishes apolipoprotein B mRNA editing and eliminates apolipoprotein B48 (nl) Targeted disruption of the mouse apobec-1 gene abolishes apolipoprotein B mRNA editing and eliminates apolipoprotein B48 (ast)
name	Targeted disruption of the mouse apobec-1 gene abolishes apolipoprotein B mRNA editing and eliminates apolipoprotein B48 (en) Targeted disruption of the mouse apobec-1 gene abolishes apolipoprotein B mRNA editing and eliminates apolipoprotein B48 (nl) Targeted disruption of the mouse apobec-1 gene abolishes apolipoprotein B mRNA editing and eliminates apolipoprotein B48 (ast)
title	wds:Q28594252-6E6ED4F1-2CD0-415E-BCC1-FD2CEEA8012A
title	Targeted disruption of the mouse apobec-1 gene abolishes apolipoprotein B mRNA editing and eliminates apolipoprotein B48 (en)
page(s)	wds:Q28594252-5B9BF3A9-4917-4A55-AFE1-7ECF449E6630
page(s)	9887–9890
instance of	wds:Q28594252-8219176F-329D-4828-805B-C1B1B3F725A5
instance of	scholarly article
main subject	wds:Q28594252-325BCBF8-ADBE-4773-93DD-CA4FB878DE93 wds:Q28594252-FBD22EF5-0A86-4590-929C-F355CFB35179
main subject	Apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1 Apolipoprotein B mRNA editing enzyme, catalytic polypeptide 2
PubMed ID	wds:Q28594252-A2964301-6755-48B9-93ED-E09C19C04F2A
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/8626621
PubMed ID	8626621
published in	wds:Q28594252-9A6A4B03-B9FD-43C5-AC05-1D4DA6F88CDE
published in	Journal of Biological Chemistry
issue	wds:Q28594252-878E9F8B-16DB-433B-AE76-9DFD330C770B
volume	wds:Q28594252-4FD9AB73-C696-41A0-8A72-5EB84962ED52
issue	17
volume	271
DOI	wds:Q28594252-54B20D7D-1DBA-4DC7-BC40-154FE20A076E
DOI	http://dx.doi.org/10.1074/JBC.271.17.9887
DOI	10.1074/JBC.271.17.9887
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q28594252
is cites work of	Superior role of apolipoprotein B48 over apolipoprotein B100 in chylomicron assembly and fat absorption: an investigation of apobec-1 knock-out and wild-type mice Influence of apoA-I and apoE on the formation of serum amyloid A-containing lipoproteins in vivo and in vitro Adeno-associated virus serotype 8 gene therapy leads to significant lowering of plasma cholesterol levels in humanized mouse models of homozygous and heterozygous familial hypercholesterolemia Tissue-specific inhibition of apolipoprotein B mRNA editing in the liver by adenovirus-mediated transfer of a dominant negative mutant APOBEC-1 leads to increased low density lipoprotein in mice

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