About: The Tec kinases Itk and Rlk regulate NKT cell maturation, cytokine production, and survival

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rdf:type	Item
description	artículu científicu espublizáu en 2008 (ast) vědecký článek publikovaný v roce 2008 (cs) наукова стаття, опублікована в березні 2008 (uk) 2008 թուականի Մարտին հրատարակուած գիտական յօդուած (hyw) 2008 թվականի մարտին հրատարակված գիտական հոդված (hy) مقالة علمية (نشرت في مارس 2008) (ar) wetenschappelijk artikel (gepubliceerd op 2008/03/01) (nl) vedecký článok (publikovaný 2008/03/01) (sk) im März 2008 veröffentlichter wissenschaftlicher Artikel (de) scientific journal article (en)
publication date	wds:Q28592807-51B712F8-EF70-4FEE-87F6-ED1147672223
publication date	2008-03-01 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q28592807-87B77B68-FAD9-43AA-AE0E-06F8756069E1
language of work or name	English
author name string	wds:Q28592807-0164E036-168E-4822-B563-66010610FA10 wds:Q28592807-0BA81AB0-1924-45D7-96C1-CA57FD75D830
author name string	Martin Felices Leslie J. Berg
rdfs:label	The Tec kinases Itk and Rlk regulate NKT cell maturation, cytokine production, and survival (en) The Tec kinases Itk and Rlk regulate NKT cell maturation, cytokine production, and survival (nl) The Tec kinases Itk and Rlk regulate NKT cell maturation, cytokine production, and survival (ast)
skos:prefLabel	The Tec kinases Itk and Rlk regulate NKT cell maturation, cytokine production, and survival (en) The Tec kinases Itk and Rlk regulate NKT cell maturation, cytokine production, and survival (nl) The Tec kinases Itk and Rlk regulate NKT cell maturation, cytokine production, and survival (ast)
name	The Tec kinases Itk and Rlk regulate NKT cell maturation, cytokine production, and survival (en) The Tec kinases Itk and Rlk regulate NKT cell maturation, cytokine production, and survival (nl) The Tec kinases Itk and Rlk regulate NKT cell maturation, cytokine production, and survival (ast)
title	wds:Q28592807-5CB8FB9C-9C76-4DDB-9705-FB13B96D3368
title	The Tec kinases Itk and Rlk regulate NKT cell maturation, cytokine production, and survival (en)
page(s)	wds:Q28592807-68C13072-0338-43B0-84C2-840CDEF21537
page(s)	3007–3018
instance of	wds:Q28592807-0D3A7CC9-6905-460E-8905-1B84D5D3BF05
instance of	scholarly article
main subject	wds:Q28592807-31930478-6552-4690-9E68-5FFA752EB3BB wds:Q28592807-A7D0F13F-E030-4761-AE4A-2C97E289EFC8
main subject	wd:Q14911918 TXK tyrosine kinase
PubMed ID	wds:Q28592807-09314A62-E955-4B70-B591-6D1AD6F22DBD
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/18292523
PubMed ID	18292523
published in	wds:Q28592807-5DC2EF9D-C25C-4A19-9754-FB1B147AF919
published in	Journal of Immunology
issue	wds:Q28592807-10FB77A7-9050-4279-9281-AD78F88D1CB4
volume	wds:Q28592807-15288A99-1131-436F-AF9D-11F07471841A
issue	5
volume	180
DOI	wds:Q28592807-1196D9E6-71E0-4B83-9DCC-10B457C4E2DC
DOI	http://dx.doi.org/10.4049/JIMMUNOL.180.5.3007
DOI	10.4049/JIMMUNOL.180.5.3007
ResearchGate publication ID	wds:Q28592807-B1ECC340-D56C-461A-A50B-00E80E07F652
ResearchGate publication ID	5558787
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q28592807
is cites work of	Essential role of Mediator subunit Med1 in invariant natural killer T-cell development Bruton's tyrosine kinase (Btk): function, regulation, and transformation with special emphasis on the PH domain The BTB-zinc finger transcriptional regulator PLZF controls the development of invariant natural killer T cell effector functions Antitumor Responses of Invariant Natural Killer T Cells The transcription factor c-Myb primes CD4+CD8+ immature thymocytes for selection into the iNKT lineage Transcriptional control of invariant NKT cell development Interleukin-2-inducible T cell kinase (Itk) network edge dependence for the maturation of iNKT cell Tec kinase Itk in gammadeltaT cells is pivotal for controlling IgE production in vivo. Enhanced development of CD4+ gammadelta T cells in the absence of Itk results in elevated IgE production Krüppel-like factor 2 regulates trafficking and homeostasis of gammadelta T cells The Ras/MAPK pathway is required for generation of iNKT cells Development of promyelocytic leukemia zinc finger-expressing innate CD4 T cells requires stronger T-cell receptor signals than conventional CD4 T cells. Development of promyelocytic zinc finger and ThPOK-expressing innate gamma delta T cells is controlled by strength of TCR signaling and Id3. Control of early stages in invariant natural killer T-cell development. Tec kinases regulate T-lymphocyte development and function: new insights into the roles of Itk and Rlk/Txk NKT cells: friend or foe during viral infections? X-linked lymphoproliferative syndrome: a genetic condition typified by the triad of infection, immunodeficiency and lymphoma. The Tec kinases Itk and Rlk regulate conventional versus innate T-cell development Girls homozygous for an IL-2-inducible T cell kinase mutation that leads to protein deficiency develop fatal EBV-associated lymphoproliferation ITK tunes IL-4-induced development of innate memory CD8+ T cells in a γδ T and invariant NKT cell-independent manner T-cell signaling regulated by the Tec family kinase, Itk. The tyrosine kinase Itk suppresses CD8+ memory T cell development in response to bacterial infection Tec family kinases: Itk signaling and the development of NKT αβ and γδ T cells Hiding lipid presentation: viral interference with CD1d-restricted invariant natural killer T (iNKT) cell activation The signaling symphony: T cell receptor tunes cytokine-mediated T cell differentiation Regulation of T-cell responses and disease by tec kinase Itk. ITK inhibitors in inflammation and immune-mediated disorders Invariant NKT cell development requires a full complement of functional CD3 zeta immunoreceptor tyrosine-based activation motifs TEC family kinases in health and disease--loss-of-function of BTK and ITK and the gain-of-function fusions ITK-SYK and BTK-SYK. Itk: the rheostat of the T cell response The transcriptional regulator PLZF induces the development of CD44 high memory phenotype T cells Interleukin-2-inducible T-cell kinase (ITK) deficiency - clinical and molecular aspects CD8α+ dendritic cell trans presentation of IL-15 to naive CD8+ T cells produces antigen-inexperienced T cells in the periphery with memory phenotype and function Characterization of a novel interaction between transcription factor TFII-I and the inducible tyrosine kinase in T cells. IL-2-inducible T-cell kinase (ITK) finds another (dance) partner...TFII-I Essential functions for ID proteins at multiple checkpoints in invariant NKT cell development. Targets for Ibrutinib Beyond B Cell Malignancies Development of innate CD4+ and CD8+ T cells in Itk-deficient mice is regulated by distinct pathways Proteasome inactivation promotes p38 mitogen-activated protein kinase-dependent phosphatidylinositol 3-kinase activation and increases interleukin-8 production in retinal pigment epithelial cells Immunodeficiency and immune dysregulation associated with proximal defects of T cell receptor signaling Targeting interleukin-2-inducible T-cell kinase (ITK) and resting lymphocyte kinase (RLK) using a novel covalent inhibitor PRN694. PDCD5 regulates iNKT cell terminal maturation and iNKT1 fate decision A unique role for ITK in survival of invariant NKT cells associated with the p53-dependent pathway in mice. The ins and outs of type I iNKT cell development IL-2-inducible T-cell kinase deficiency: clinical presentation and therapeutic approach Itk signals promote neuroinflammation by regulating CD4+ T-cell activation and trafficking. IL-2-inducible T cell kinase tunes T regulatory cell development and is required for suppressive function

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