About: Brca2 deficiency in the murine small intestine sensitizes to p53-dependent apoptosis and leads to the spontaneous deletion of stem cells

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Brca2 deficiency in the murine small intestine sensitizes to p53-dependent apoptosis and leads to the spontaneous deletion of stem cells Goto Sponge NotDistinct Permalink

An Entity of Type : wikibase:Item, within Data Space : wikidata.demo.openlinksw.com associated with source document(s)

scientific journal article

Attributes	Values
rdf:type	Item
description	artículu científicu espublizáu en 2005 (ast) vědecký článek publikovaný v roce 2005 (cs) 2005 թվականի մայիսին հրատարակված գիտական հոդված (hy) 2005 թուականի Մայիսին հրատարակուած գիտական յօդուած (hyw) наукова стаття, опублікована в травні 2005 (uk) scientific journal article (en) im Mai 2005 veröffentlichter wissenschaftlicher Artikel (de) wetenschappelijk artikel (gepubliceerd op 2005/05/26) (nl) vedecký článok (publikovaný 2005/05/26) (sk) مقالة علمية (نشرت في 26-5-2005) (ar)
publication date	wds:Q28592124-F09EEA63-56C1-47AE-8D5E-BFD7328F1AE0
publication date	2005-05-01 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q28592124-0462035B-6257-49F2-845B-DE1D06A6D40E
language of work or name	English
cites work	wds:Q28592124-0458AF8A-6417-41B9-83DA-498EC546BCDA wds:Q28592124-04615C41-68FA-4559-AF93-E669F6BBDE38 wds:Q28592124-073865E6-2159-47ED-9A4A-F46DFA41929A wds:Q28592124-12B95974-9FA5-4940-A30F-78F19D5A294F wds:Q28592124-235564AC-B11E-4032-903D-8EDB8FC448B0 wds:Q28592124-23675371-3E38-4A64-BDAC-7DF39CE4B594 wds:Q28592124-2447B329-61D2-4F76-89B6-781E6A109F97 wds:Q28592124-26853994-E422-4AFC-8F2B-7E2594728C87 wds:Q28592124-2A2FD4E2-15BF-4D1D-8DC9-14088B4B5466 wds:Q28592124-405A41CB-C272-485C-941C-B8EB8C65C858 wds:Q28592124-4A787EAA-0EAF-44E6-8018-350898BECE2B wds:Q28592124-6F35756F-54B6-4506-AB17-2DA0F8582292 wds:Q28592124-70B94F9F-090B-46D1-B00F-9B5378DAC0C1 wds:Q28592124-715D07AA-DF8C-4257-AC86-07286437C86B wds:Q28592124-736585BA-F80C-4427-9165-3E553E52C846 wds:Q28592124-8D8E0094-084F-40F2-BFC0-0E3A08CC4C1B wds:Q28592124-9A6121EE-03E4-4BBB-A2EE-F8751683DC7E wds:Q28592124-A88AFE8C-3E6B-497A-8CC1-A3BC5C1F434B wds:Q28592124-B540D6C1-C7BE-4539-A0CB-D508D2C5B733 wds:Q28592124-C1F147DC-B333-4BCC-A452-E29056609634 wds:Q28592124-C7A585D3-0C9B-4696-BE74-EA46187587B7 wds:Q28592124-D3B8792E-4329-4B6D-AD74-7804C9A01FFE wds:Q28592124-D89AE6A9-08DA-4C23-9C9E-217E283F7E90 wds:Q28592124-E7822773-64C0-4864-8173-A2119F8A5960
cites work	Caspase activation during spontaneous and radiation-induced apoptosis in the murine intestine Role of BRCA2 in control of the RAD51 recombination and DNA repair protein. Cancer risks in BRCA2 mutation carriers Loss of Apc in vivo immediately perturbs Wnt signaling, differentiation, and migration The BRC repeats in BRCA2 are critical for RAD51 binding and resistance to methyl methanesulfonate treatment Embryonic lethality and radiation hypersensitivity mediated by Rad51 in mice lacking Brca2 Double-strand break repair deficiency and radiation sensitivity in BRCA2 mutant cancer cells Brca2 is required for embryonic cellular proliferation in the mouse The intestinal epithelial stem cell Involvement of Brca2 in DNA repair Targeted mutations of breast cancer susceptibility gene homologs in mice: lethal phenotypes of Brca1, Brca2, Brca1/Brca2, Brca1/p53, and Brca2/p53 nullizygous embryos Role of BRCA gene dysfunction in breast and ovarian cancer predisposition Generalized lacZ expression with the ROSA26 Cre reporter strain Deletion of Brca2 exon 27 causes hypersensitivity to DNA crosslinks, chromosomal instability, and reduced life span in mice. Brca2 (XRCC11) deficiency results in radioresistant DNA synthesis and a higher frequency of spontaneous deletions Inducible Cre-mediated control of gene expression in the murine gastrointestinal tract: effect of loss of beta-catenin The Fanconi anaemia/BRCA pathway Insights into DNA recombination from the structure of a RAD51-BRCA2 complex Synergistic tumor suppressor activity of BRCA2 and p53 in a conditional mouse model for breast cancer. Field cancerization, clonality, and epithelial stem cells: the spread of mutated clones in epithelial sheets Brca2 deficiency does not impair mammary epithelium development but promotes mammary adenocarcinoma formation in p53(+/-) mutant mice. Development of mammary adenocarcinomas by tissue-specific knockout of Brca2 in mice. Distinct functions of BRCA1 and BRCA2 in double-strand break repair The ability to engage enterocyte apoptosis does not predict long-term crypt survival in p53 and Msh2 deficient mice
author name string	wds:Q28592124-5C551D9E-B6D8-4A60-91BF-7FD674753F9B
author name string	Teresa Patrick
rdfs:label	Brca2 deficiency in the murine small intestine sensitizes to p53-dependent apoptosis and leads to the spontaneous deletion of stem cells (en) Brca2 deficiency in the murine small intestine sensitizes to p53-dependent apoptosis and leads to the spontaneous deletion of stem cells (nl) Brca2 deficiency in the murine small intestine sensitizes to p53-dependent apoptosis and leads to the spontaneous deletion of stem cells (ast)
skos:prefLabel	Brca2 deficiency in the murine small intestine sensitizes to p53-dependent apoptosis and leads to the spontaneous deletion of stem cells (en) Brca2 deficiency in the murine small intestine sensitizes to p53-dependent apoptosis and leads to the spontaneous deletion of stem cells (nl) Brca2 deficiency in the murine small intestine sensitizes to p53-dependent apoptosis and leads to the spontaneous deletion of stem cells (ast)
name	Brca2 deficiency in the murine small intestine sensitizes to p53-dependent apoptosis and leads to the spontaneous deletion of stem cells (en) Brca2 deficiency in the murine small intestine sensitizes to p53-dependent apoptosis and leads to the spontaneous deletion of stem cells (nl) Brca2 deficiency in the murine small intestine sensitizes to p53-dependent apoptosis and leads to the spontaneous deletion of stem cells (ast)
author	wds:Q28592124-16D91E78-E13F-4AF7-9561-9EFBF7CD5572 wds:Q28592124-25B45B58-DE3E-4268-9B63-CF8D06F49A94 wds:Q28592124-51D3FAEB-782F-4286-84CB-389F46E9189C wds:Q28592124-933D09BA-FF1E-4256-B9D0-EA6DBF5D91E2
author	Owen J Sansom Alan R. Clarke Douglas J Winton Trevor Hay
title	wds:Q28592124-2D88160D-5C8E-45AD-BB09-D725A7C3B1A9
title	Brca2 deficiency in the murine small intestine sensitizes to p53-dependent apoptosis and leads to the spontaneous deletion of stem cells (en)
page(s)	wds:Q28592124-57DC8505-B631-46EC-86C1-87BC50A97665
page(s)	3842-3846
instance of	wds:Q28592124-FE173333-F983-4C59-9F6C-638F92D30C33
instance of	scholarly article
main subject	wds:Q28592124-42532588-8717-4C97-B2FA-1498E6FF403E wds:Q28592124-4F85C82B-7D9A-4B60-848A-07EBA8134066
main subject	apoptotic process Breast cancer 2, early onset
PubMed ID	wds:Q28592124-B22124A4-A478-4F3A-9E02-3CCE263AE0F9
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/15735671
PubMed ID	15735671
published in	wds:Q28592124-20DAAA5E-DD99-4103-B295-06BDA30884A5
published in	Oncogene
issue	wds:Q28592124-94DF4F72-F498-4D0E-91BB-39CBDBD34837
volume	wds:Q28592124-72162D54-627D-4249-AAA3-81AADC6D0F29
issue	23

Faceted Search & Find service v1.16.117 as of May 05 2024

Alternative Linked Data Documents: ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3239 as of May 5 2024, on Linux (x86_64-centos_6-linux-gnu), Single-Server Edition (378 GB total memory, 193 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software