About: Glypican-3 inhibits Hedgehog signaling during development by competing with patched for Hedgehog binding

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About: Glypican-3 inhibits Hedgehog signaling during development by competing with patched for Hedgehog binding Goto Sponge NotDistinct Permalink

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Attributes	Values
rdf:type	Item
description	artículu científicu espublizáu en 2008 (ast) vědecký článek publikovaný v roce 2008 (cs) 2008 թվականի մայիսին հրատարակված գիտական հոդված (hy) наукова стаття, опублікована в травні 2008 (uk) 2008 թուականի Մայիսին հրատարակուած գիտական յօդուած (hyw) مقالة علمية (نشرت في مايو 2008) (ar) vedecký článok (publikovaný 2008/05/01) (sk) wetenschappelijk artikel (gepubliceerd op 2008/05/01) (nl) im Mai 2008 veröffentlichter wissenschaftlicher Artikel (de) scientific journal article (en)
publication date	wds:Q28590274-E6EEDB3D-DECC-4598-A06C-6DA573EE843C
publication date	2008-05-01 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q28590274-D6FC969B-25A4-43E1-A303-5C9F4C46CDF7
language of work or name	English
author name string	wds:Q28590274-39376482-7B6A-42EE-8547-AA96AB53210C wds:Q28590274-4A142C33-FEE1-4D40-9E66-A7E781663888 wds:Q28590274-510515FA-48E5-4769-B0F9-59F4D640A7B9 wds:Q28590274-74737DF4-A642-46C6-B73A-616011AF9AA4 wds:Q28590274-C3572788-7403-43F1-A1B9-37249CFEF47F wds:Q28590274-F99BF9B7-3A1F-4FAF-8F32-872450ADA0CC
OpenCitations bibliographic resource ID	wds:Q28590274-EE4BC375-A4AB-47AF-B125-101E2A4CCFF6
OpenCitations bibliographic resource ID	https://w3id.org/oc/corpus/br/273950
author name string	Ping Xu Fuchuan Li Wen Shi Jorge Filmus Angela Jia Mariana I. Capurro
OpenCitations bibliographic resource ID	273950
rdfs:label	Glypican-3 inhibits Hedgehog signaling during development by competing with patched for Hedgehog binding (en) Glypican-3 inhibits Hedgehog signaling during development by competing with patched for Hedgehog binding (nl) Glypican-3 inhibits Hedgehog signaling during development by competing with patched for Hedgehog binding (ast)
skos:prefLabel	Glypican-3 inhibits Hedgehog signaling during development by competing with patched for Hedgehog binding (en) Glypican-3 inhibits Hedgehog signaling during development by competing with patched for Hedgehog binding (nl) Glypican-3 inhibits Hedgehog signaling during development by competing with patched for Hedgehog binding (ast)
name	Glypican-3 inhibits Hedgehog signaling during development by competing with patched for Hedgehog binding (en) Glypican-3 inhibits Hedgehog signaling during development by competing with patched for Hedgehog binding (nl) Glypican-3 inhibits Hedgehog signaling during development by competing with patched for Hedgehog binding (ast)
title	wds:Q28590274-D2FC9B4E-CFEB-4CA9-95C1-6898ACF953D6
title	Glypican-3 inhibits Hedgehog signaling during development by competing with patched for Hedgehog binding (en)
page(s)	wds:Q28590274-8B34D677-ADE6-4C5A-9634-157CCDDE36B8
page(s)	700–711
instance of	wds:Q28590274-D9F2329C-03D2-4DD8-A969-41441D54035F
instance of	scholarly article
main subject	wds:Q28590274-70422E1B-E8FD-46B5-8CB8-1F277A24935B wds:Q28590274-715B3D67-757A-4E28-BAB8-5F2BB911CCA8 wds:Q28590274-8808E190-32CF-42D7-A72A-8F35843FDEE0 wds:Q28590274-98B60FFA-B9F4-4FEC-BD93-54F6C26FC0FF
main subject	wd:Q14860215 Lysosomal-associated membrane protein 1 Glypican 3 Transferrin
PubMed ID	wds:Q28590274-C473DFBA-9E2E-4BA2-A197-3032A361BBAC
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/18477453
PubMed ID	18477453
published in	wds:Q28590274-8D48C66E-7182-44AA-ABAC-C8D3CBEB21FA
published in	Developmental Cell
issue	wds:Q28590274-117F0E85-D0FE-4A6B-BE92-D1F23E84B066
volume	wds:Q28590274-8E64FE37-ADA2-4485-A52F-EF8FD46728D9
issue	5
volume	14
DOI	wds:Q28590274-B781CF6D-EE7A-4A53-9EBA-663975F89298
DOI	http://dx.doi.org/10.1016/J.DEVCEL.2008.03.006
DOI	10.1016/J.DEVCEL.2008.03.006
ResearchGate publication ID	wds:Q28590274-9F4DA17A-FCE8-44BC-AA34-B096289A7329
ResearchGate publication ID	5375003
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q28590274
is cites work of	Glypican-3: a marker and a therapeutic target in hepatocellular carcinoma Glypican-3: a new target for cancer immunotherapy Glypican-3 antibodies: a new therapeutic target for liver cancer Knockdown of GPC3 inhibits the proliferation of Huh7 hepatocellular carcinoma cells through down-regulation of YAP. Oncogenic activation of glypican-3 by c-Myc in human hepatocellular carcinoma. Proteoglycans in cancer biology, tumour microenvironment and angiogenesis Critical analysis of the potential of targeting GPC3 in hepatocellular carcinoma Targeting of heparanase-modified syndecan-1 by prosecretory mitogen lacritin requires conserved core GAGAL plus heparan and chondroitin sulfate as a novel hybrid binding site that enhances selectivity Glypicans Glypican-3 is a prognostic factor and an immunotherapeutic target in hepatocellular carcinoma Insights into the key roles of proteoglycans in breast cancer biology and translational medicine Principles of liver regeneration and growth homeostasis Advances in liver regeneration Overgrowth of a mouse model of Simpson-Golabi-Behmel syndrome is partly mediated by Indian hedgehog Loss of glypican-3 function causes growth factor-dependent defects in cardiac and coronary vascular development Overlapping roles and collective requirement for the coreceptors GAS1, CDO, and BOC in SHH pathway function Interactions between Hedgehog proteins and their binding partners come into view Proteoglycan form and function: A comprehensive nomenclature of proteoglycans Breast and ovarian cancers: a survey and possible roles for the cell surface heparan sulfate proteoglycans Mesenchymal stem cells, neural lineage potential, heparan sulfate proteoglycans and the matrix. Two distinct sites in sonic Hedgehog combine for heparan sulfate interactions and cell signaling functions Heparan sulfate proteoglycans containing a glypican 5 core and 2-O-sulfo-iduronic acid function as Sonic Hedgehog co-receptors to promote proliferation Dual roles of the Cardin-Weintraub motif in multimeric Sonic hedgehog. LRP1 mediates Hedgehog-induced endocytosis of the GPC3-Hedgehog complex Indian hedgehog mutations causing brachydactyly type A1 impair Hedgehog signal transduction at multiple levels Proteoglycans in stem cells Hedgehog signaling in development and cancer. Heparan sulfate is required for embryonic stem cells to exit from self-renewal The Hedgehog pathway: role in cell differentiation, polarity and proliferation Syndecan-1 regulates BMP signaling and dorso-ventral patterning of the ectoderm during early Xenopus development. Proteoglycan interactions with Sonic Hedgehog specify mitogenic responses Structure of the protein core of the glypican Dally-like and localization of a region important for hedgehog signaling

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