About: GATA3 controls the expression of CD5 and the T cell receptor during CD4 T cell lineage development

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About: GATA3 controls the expression of CD5 and the T cell receptor during CD4 T cell lineage development Goto Sponge NotDistinct Permalink

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description	artículu científicu espublizáu en 2007 (ast) vědecký článek publikovaný v roce 2007 (cs) 2007 թվականի ապրիլին հրատարակված գիտական հոդված (hy) 2007 թուականի Ապրիլին հրատարակուած գիտական յօդուած (hyw) наукова стаття, опублікована у квітні 2007 (uk) مقالة علمية (نشرت في أبريل 2007) (ar) vedecký článok (publikovaný 2007/04/01) (sk) wetenschappelijk artikel (gepubliceerd op 2007/04/01) (nl) scientific journal article (en) im April 2007 veröffentlichter wissenschaftlicher Artikel (de)
publication date	wds:Q28589154-E11C162C-7B40-4E98-BF66-14DEE6124710
publication date	2007-04-01 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q28589154-658B90AF-0A40-43A7-BFD8-85B4A0451802
language of work or name	English
cites work	wds:Q28589154-01741B23-3BA1-4522-A692-34A4FC96FE64 wds:Q28589154-01A383DD-6D0E-4452-A80A-1A438730DDD4 wds:Q28589154-05891991-5C37-4393-92A0-C1163E0D475C wds:Q28589154-0A49B2AF-60B4-45A3-B477-7F30AAA67ED4 wds:Q28589154-1A9F32C8-7E57-4AC1-B236-E70423D334FD wds:Q28589154-2F960AE5-430B-4E63-BD6E-1A593214C3AA wds:Q28589154-339C9775-460E-41D5-8849-119A31C6464C wds:Q28589154-3AE360B9-7A26-4716-930A-634690CCC646 wds:Q28589154-4A9C66A4-7FB1-4CBE-8C40-ECC6E857436B wds:Q28589154-4DA05B39-10E0-4F08-9C91-190AF7904B9E wds:Q28589154-4DEE5B7F-DAB4-47AE-ACCE-30B91F554DB1 wds:Q28589154-502F7541-80BC-4457-B08A-7158B383AA3A wds:Q28589154-537EC5A3-FA80-4647-8689-F8794A9D4897 wds:Q28589154-57CEA353-42F8-4C01-877C-193F78328068 wds:Q28589154-6DC1106E-9286-4777-B63A-E793CC62FDC9 wds:Q28589154-745E9F55-D038-40FA-9F77-B0AE5524E0E1 wds:Q28589154-8688A929-43B9-4F96-B01F-E554EBBB4DBF wds:Q28589154-87FFAE9D-D7DC-4727-A40D-E97DAB338761 wds:Q28589154-901C28B6-8D69-4A44-8763-8514FF4D0AB0 wds:Q28589154-96AFC52F-D470-47DF-87B2-DCF195E6D1A7 wds:Q28589154-96B92402-CC7E-460E-93F7-CC8412A55EC1 wds:Q28589154-9DEBE09F-64D3-4848-B825-B50BD80E9D9F wds:Q28589154-ADBDDB2E-3C67-405C-86BA-57439B7C08BB wds:Q28589154-BA2B38F1-4509-434E-9A93-19EEE796D64B wds:Q28589154-BD160080-E0F1-4E92-AB17-848A5C0A4E3D wds:Q28589154-C053869B-6757-4E4D-9515-2B89841D9E65 wds:Q28589154-CD9F2116-0C8B-426B-8500-42996C5FCCF9 wds:Q28589154-D254F51B-8447-442C-88C0-48E3353EAF71 wds:Q28589154-D95CF4E4-25F5-43AE-A30A-1EDD6E43E6E8 wds:Q28589154-DBE0EA6A-8B6B-4392-BA84-741A35C0FA7B wds:Q28589154-DF075BE3-261E-4C35-9739-A7522619FAE7 wds:Q28589154-E8CD5640-E8C0-4979-A4BA-CF83600E7F8A wds:Q28589154-F16979C9-2FE6-4593-A6CE-2E73DB18AD03 wds:Q28589154-FFEB8FC1-B225-44DD-984E-A1AD92AA05D3
cites work	ROG, repressor of GATA, regulates the expression of cytokine genes Regulation of Th2 differentiation and Il4 locus accessibility. CD4-CD8 lineage commitment: an inside view Activation events during thymic selection CD5 expression is developmentally regulated by T cell receptor (TCR) signals and TCR avidity CD69 expression during selection and maturation of CD4+8+ thymocytes. A role for CD5 in TCR-mediated signal transduction and thymocyte selection Critical roles for transcription factor GATA-3 in thymocyte development Friend of GATA-1 represses GATA-3-dependent activity in CD4+ T cells. GATA-3 deficiency abrogates the development and maintenance of T helper type 2 cells GATA-1 forms distinct activating and repressive complexes in erythroid cells TAL1 and LIM-only proteins synergistically induce retinaldehyde dehydrogenase 2 expression in T-cell acute lymphoblastic leukemia by acting as cofactors for GATA3 The LIM-only protein Lmo2 is a bridging molecule assembling an erythroid, DNA-binding complex which includes the TAL1, E47, GATA-1 and Ldb1/NLI proteins Unexpectedly complex regulation of CD4/CD8 coreceptor expression supports a revised model for CD4+CD8+ thymocyte differentiation. Induction by antigen of intrathymic apoptosis of CD4+CD8+TCRlo thymocytes in vivo Transcription factor GATA-3 is required for development of the T-cell lineage Targeted disruption of the GATA3 gene causes severe abnormalities in the nervous system and in fetal liver haematopoiesis The human enhancer-binding protein Gata3 binds to several T-cell receptor regulatory elements A critical role for Dnmt1 and DNA methylation in T cell development, function, and survival. GATA-3 expression is controlled by TCR signals and regulates CD4/CD8 differentiation Expression of the transcription factor GATA-3 is required for the development of the earliest T cell progenitors and correlates with stages of cellular proliferation in the thymus Restoration of early thymocyte differentiation in T-cell receptor beta-chain-deficient mutant mice by transmembrane signaling through CD3 epsilon A mouse Y chromosome gene encoded by a region essential for spermatogenesis and expression of male-specific minor histocompatibility antigens. The E47 transcription factor negatively regulates CD5 expression during thymocyte development Fine tuning of TCR signaling by CD5. CD4/CD8-lineage differentiation in the thymus: from nuclear effectors to membrane signals Enforced expression of GATA-3 during T cell development inhibits maturation of CD8 single-positive cells and induces thymic lymphoma in transgenic mice. Transcriptome and phenotypic analysis reveals Gata3-dependent signalling pathways in murine hair follicles CD3 epsilon-mediated signals rescue the development of CD4+CD8+ thymocytes in RAG-2-/- mice in the absence of TCR beta chain expression. CD3 components at the surface of pro-T cells can mediate pre-T cell developmentin vivo Enforced expression of GATA-3 in transgenic mice inhibits Th1 differentiation and induces the formation of a T1/ST2-expressing Th2-committed T cell compartment in vivo. An influence of CD5 on the selection of CD4-lineage T cells. Premature TCR alpha beta expression and signaling in early thymocytes impair thymocyte expansion and partially block their development Regulation of RAG-1 and CD69 expression in the thymus during positive and negative selection
author name string	wds:Q28589154-3ADA80E9-5BAB-4370-B8A7-0C1062D7F678 wds:Q28589154-42CAF730-1E48-4C5F-9EAE-D7C17FF1C542 wds:Q28589154-4753D7A6-C9A6-458A-8C7E-B310CD26AEF6 wds:Q28589154-843AACA1-9627-44B5-A3A5-6D5DAE42237D wds:Q28589154-C2D34116-ABE3-4FB3-9BEF-93AF54E99E0A wds:Q28589154-CE8E1FE8-516B-4BA3-B470-F937E17EA026
author name string	Dorota Kurek Jan Piet van Hamburg Kam-Wing Ling Rudolf W. Hendriks Gemma M. Dingjan Marjolein J. W. de Bruijn
rdfs:label	GATA3 controls the expression of CD5 and the T cell receptor during CD4 T cell lineage development (en) GATA3 controls the expression of CD5 and the T cell receptor during CD4 T cell lineage development (nl) GATA3 controls the expression of CD5 and the T cell receptor during CD4 T cell lineage development (ast)
skos:prefLabel	GATA3 controls the expression of CD5 and the T cell receptor during CD4 T cell lineage development (en) GATA3 controls the expression of CD5 and the T cell receptor during CD4 T cell lineage development (nl)

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