About: Deficiency of FLCN in mouse kidney led to development of polycystic kidneys and renal neoplasia

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About: Deficiency of FLCN in mouse kidney led to development of polycystic kidneys and renal neoplasia Goto Sponge NotDistinct Permalink

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description	wissenschaftlicher Artikel (de) artículu científicu espublizáu en 2008 (ast) vědecký článek publikovaný v roce 2008 (cs) наукова стаття, опублікована в січні 2008 (uk) 2008 թվականի հունվարին հրատարակված գիտական հոդված (hy) 2008 թուականի Յունուարին հրատարակուած գիտական յօդուած (hyw) مقالة علمية (نشرت عام 2008) (ar) vedecký článok (publikovaný 2008/01/01) (sk) wetenschappelijk artikel (gepubliceerd op 2008/01/01) (nl) article publié dans la revue scientifique PLoS ONE (fr) scientific journal article (en)
publication date	wds:Q28587662-2831457D-E1A1-47D4-8650-6BCFB93905F3
publication date	2008-10-30 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q28587662-06FBA4DD-CA36-4618-BFF2-30776013B567
language of work or name	English
cites work	wds:Q28587662-03EA4FD7-C6CE-40B0-86EA-79BA9E4825F1 wds:Q28587662-06EFF3BA-C512-4D0A-8BC2-7474E3838CDA wds:Q28587662-0949BC56-7BA2-4769-AAB2-47EA269A0418 wds:Q28587662-12E359DB-7E06-473C-98BE-BFEC03447290 wds:Q28587662-18B4E136-7515-492E-AA7D-34987DDA331F wds:Q28587662-22043EEE-9477-4293-879C-6F5DB87B3BA5 wds:Q28587662-2FEC8368-5CB7-43B7-BE99-272A940E09B6 wds:Q28587662-30AA1F6E-F092-483C-AD6B-BA19DDA31417 wds:Q28587662-37EE8C44-E38D-4C98-9B64-8A1A3444FA26 wds:Q28587662-39ECEF6B-5C90-4485-857E-D0F8CBB3ED14 wds:Q28587662-4503DB97-2759-45E3-AF64-91933924806E wds:Q28587662-6C18D515-93BC-4343-80AC-E7FB5412CA02 wds:Q28587662-7D174C66-B098-4D58-B4B7-72B2AF511235 wds:Q28587662-7E855982-0B74-4F4A-847C-1FEA330D4C0E wds:Q28587662-7EF6BE5C-21C4-4D79-B654-678FF304B6C0 wds:Q28587662-8605BDBD-13A9-4C14-9FBE-1BE9CF0B92CF wds:Q28587662-9037ED42-B4E1-474D-B7A7-BBD14EC2BCE8 wds:Q28587662-99882FD7-02D4-4132-AADC-66E0581A5BF3 wds:Q28587662-9FC4EC55-E2DA-4678-AB87-FB71FCB62F68 wds:Q28587662-A207EAFA-672A-4306-98BF-AD5105BC3D7A wds:Q28587662-A3B6D7CB-1ADB-441C-A65B-4B0943C3F892 wds:Q28587662-A8B75773-4797-4A24-9666-3B6414A9FC42 wds:Q28587662-BC194D19-534D-419A-AA4F-D2FC018CF3C6 wds:Q28587662-BE747DD2-7D39-4CB6-9CB3-B3C4F99D0766 wds:Q28587662-BF1FB0F4-4C73-4BBB-8A35-AAD59F9B37B7 wds:Q28587662-C3116B62-EE8A-4E2B-947A-F508DA3913B5 wds:Q28587662-C7723B0A-B01D-4CB2-B525-16140AFE1279 wds:Q28587662-D1137E9A-A756-443F-8D46-789F31A32022 wds:Q28587662-E46F9FB9-E7B8-4CB9-B5AA-33B8392F651D wds:Q28587662-E7099755-6255-4A64-9EB0-ABBD9FABEE72 wds:Q28587662-EDA88E43-D34F-48A9-91B8-23C214A48F64 wds:Q28587662-F07FB223-01F8-43A9-A97B-97FFAB768513 wds:Q28587662-F3C6D33C-74D6-4282-8A42-E3BA0A27FE37 wds:Q28587662-F93A839D-7F3A-4445-AD3D-4EFA9C9A79DD
cites work	Expression of Birt-Hogg-Dubé gene mRNA in normal and neoplastic human tissues Birt-Hogg-Dubé syndrome: mapping of a novel hereditary neoplasia gene to chromosome 17p12-q11.2. High frequency of somatic frameshift BHD gene mutations in Birt-Hogg-Dubé-associated renal tumors. Germline BHD-mutation spectrum and phenotype analysis of a large cohort of families with Birt-Hogg-Dubé syndrome Birt-Hogg-Dubé syndrome, a genodermatosis associated with spontaneous pneumothorax and kidney neoplasia, maps to chromosome 17p11.2. Folliculin encoded by the BHD gene interacts with a binding protein, FNIP1, and AMPK, and is involved in AMPK and mTOR signaling Mutations in a novel gene lead to kidney tumors, lung wall defects, and benign tumors of the hair follicle in patients with the Birt-Hogg-Dubé syndrome Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome Epithelial-specific Cre/lox recombination in the developing kidney and genitourinary tract. The Drosophila homolog of the human tumor suppressor gene BHD interacts with the JAK-STAT and Dpp signaling pathways in regulating male germline stem cell maintenance. Hereditary Multiple Fibrofolliculomas With Trichodiscomas and Acrochordons Renal Tumors in the Birt-Hogg-Dubé Syndrome Dysregulation of the TSC-mTOR pathway in human disease A germ-line insertion in the Birt-Hogg-Dubé (BHD) gene gives rise to the Nihon rat model of inherited renal cancer A mutation in the canine BHD gene is associated with hereditary multifocal renal cystadenocarcinoma and nodular dermatofibrosis in the German Shepherd dog. Birt-Hogg-Dube syndrome: an autosomal dominant disorder with predisposition to cancers of the kidney, fibrofolliculomas, and focal cutaneous mucinosis PTEN mutation spectrum and genotype-phenotype correlations in Bannayan-Riley-Ruvalcaba syndrome suggest a single entity with Cowden syndrome Defective placental vasculogenesis causes embryonic lethality in VHL-deficient mice Cystic renal cell carcinoma Inactivation of BHD in sporadic renal tumors. Kidney-targeted Birt-Hogg-Dube gene inactivation in a mouse model: Erk1/2 and Akt-mTOR activation, cell hyperproliferation, and polycystic kidneys Renal cystic neoplasms and renal neoplasms associated with cystic renal diseases: pathogenetic and molecular links Birt-Hogg-Dubé Syndrome The Birt-Hogg-Dube and tuberous sclerosis complex homologs have opposing roles in amino acid homeostasis in Schizosaccharomyces pombe. Targeted inactivation of fh1 causes proliferative renal cyst development and activation of the hypoxia pathway Collecting duct carcinoma associated with oncocytoma Natural history of the Nihon rat model of BHD. Multilocular cystic renal cell carcinoma: a series of 12 cases and review of the literature Cystic renal cell carcinoma: CT findings simulating a benign hyperdense cyst Cystic renal cell carcinoma: biology and clinical behavior Tubulocystic carcinoma of the kidney: a new entity among renal tumors Exclusion of PTEN, CTNNB1, and PTCH as candidate genes for Birt-Hogg-Dube syndrome Multilocular cystic renal cell carcinoma Multilocular, predominantly cystic, renal cell carcinoma: an unusual gross appearance (a case report).
author name string	wds:Q28587662-07F760F4-E472-4C57-8B7F-F40029715858 wds:Q28587662-20175E55-2D9E-4C80-9CF4-AA08C029224D wds:Q28587662-2198A254-D249-4492-A71E-8A4F3D4A96A1 wds:Q28587662-2508FE1B-C067-4A94-8C92-2922261F36D4 wds:Q28587662-3790CF8E-2CF4-4947-BDC5-1F4161A9FE62 wds:Q28587662-5ACEDDCA-DE73-4057-8C3D-F04E52DCA831 wds:Q28587662-7632D67C-7DF1-45DD-A6D9-E67E17556C35 wds:Q28587662-A8630C62-0ED4-440C-B1A0-CB3F5A504249 wds:Q28587662-A8AA289F-8222-4D2C-BA62-02D7A73EB988 wds:Q28587662-B8B4C46C-AEB8-4E24-960D-795D060367C5 wds:Q28587662-CB6BADD5-BCEA-4E90-A82C-8DCA7C00F5A4 wds:Q28587662-CBCC9237-5049-43E9-BE98-546CF6E4AFFF wds:Q28587662-D5949395-0A68-48C4-84FB-1E6E3F34CE9B wds:Q28587662-D6071C87-A3D6-410D-B1A5-8D692926BD3E wds:Q28587662-FDBB8F3B-A487-4839-A6B8-D9DE88B07A8C
OpenCitations bibliographic resource ID	wds:Q28587662-4F66D5B2-DA40-404A-A704-037B172D652A

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