About: Cbfbeta interacts with Runx2 and has a critical role in bone development

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description	articolo scientifico (it) artículu científicu espublizáu en 2002 (ast) vědecký článek publikovaný v roce 2002 (cs) наукова стаття, опублікована в грудні 2002 (uk) 2002 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած (hyw) 2002 թվականի դեկտեմբերին հրատարակված գիտական հոդված (hy) مقالة علمية (نشرت في ديسمبر 2002) (ar) vedecký článok (publikovaný 2002/12/01) (sk) wetenschappelijk artikel (gepubliceerd op 2002/12/01) (nl) مقالة علمية تنشرت ف 1 دجنبر 2002 (ary) im Dezember 2002 veröffentlichter wissenschaftlicher Artikel (de) scientific journal article (en)
publication date	wds:Q28586662-E3A09C71-1740-4166-9871-5B0BC8E18057
publication date	2002-12-01 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q28586662-C33852BF-39D1-4BF3-9F6E-D62ADFE890F7
language of work or name	English
cites work	wds:Q28586662-09DE840A-84D8-4184-A8F5-9274E5500F8A wds:Q28586662-0C9D8A9C-1CBB-456E-B750-055D06460EAF wds:Q28586662-2A93A380-5114-4FB2-A972-1493E13781C7 wds:Q28586662-2ACE9030-2C89-4BAA-B709-87CBA4372963 wds:Q28586662-31F20ACE-4006-4C55-B744-691A569330CC wds:Q28586662-321DA592-1AFA-4150-894E-FB1531E85F12 wds:Q28586662-563853E5-F513-4E14-B25A-D71951B427C2 wds:Q28586662-57B6061C-9E45-4A3B-ADC3-64258CEE047A wds:Q28586662-5A32D05D-EBB2-42FC-97EF-DFDF424AAD8D wds:Q28586662-5F20E214-FC33-4315-A4F7-8C47C01EBBC1 wds:Q28586662-62175D38-31A6-497F-BBF7-6ECC0F980C80 wds:Q28586662-644FC0EF-EADD-4CB7-80A7-995991C9C281 wds:Q28586662-6E329F12-F3DC-48A1-8309-2E0D05D46A5A wds:Q28586662-706D214D-E390-4AFD-9DF4-0BB8FF53E980 wds:Q28586662-804533DA-6BFF-436A-98B5-9C4A58A82C92 wds:Q28586662-860C4045-82C6-484B-B411-AF6D5C222BAF wds:Q28586662-86F25781-33E6-4DDA-A4BB-98913EA5F4B5 wds:Q28586662-8F1AB6F6-5017-48B8-9E9C-E5DF4D23D095 wds:Q28586662-8F439D74-7084-44C9-8CB2-A40308AA98AE wds:Q28586662-927B1538-6A7F-4EE4-8BF5-765FC7A17C16 wds:Q28586662-93673681-D4F8-4162-BD6E-B0C5C7A776CD wds:Q28586662-AF769F65-04E6-436A-A1C4-CF48D0C0079B wds:Q28586662-B2AEC10A-1F40-46AC-9F79-95E42BCAEC51 wds:Q28586662-C11C3BCC-6EFF-470D-AD9E-24769C077F0A wds:Q28586662-D336E2BF-1A5B-4F66-AE45-E5EC5BE7B59E wds:Q28586662-D407E208-4733-47E3-AF66-F57968018024 wds:Q28586662-E38990DB-B5D6-445F-98F3-0EBEB0277671 wds:Q28586662-F8E7F0C1-A98B-406A-BD7D-43CD91989B78
cites work	Functional analysis of RUNX2 mutations in Japanese patients with cleidocranial dysplasia demonstrates novel genotype-phenotype correlations Absence of fetal liver hematopoiesis in mice deficient in transcriptional coactivator core binding factor beta The CBFbeta subunit is essential for CBFalpha2 (AML1) function in vivo Cbfa1, a candidate gene for cleidocranial dysplasia syndrome, is essential for osteoblast differentiation and bone development Indian hedgehog signaling regulates proliferation and differentiation of chondrocytes and is essential for bone formation Two domains unique to osteoblast-specific transcription factor Osf2/Cbfa1 contribute to its transactivation function and its inability to heterodimerize with Cbfbeta Regulation of chondrocyte differentiation by Cbfa1 Osf2/Cbfa1: a transcriptional activator of osteoblast differentiation Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts runt homology domain transcription factors (Runx, Cbfa, and AML) mediate repression of the bone sialoprotein promoter: evidence for promoter context-dependent activity of Cbfa proteins Mutations in the RUNX2 gene in patients with cleidocranial dysplasia Core-binding factors in haematopoiesis and leukaemia The leukemic protein core binding factor beta (CBFbeta)-smooth-muscle myosin heavy chain sequesters CBFalpha2 into cytoskeletal filaments and aggregates Interaction and functional cooperation of PEBP2/CBF with Smads. Synergistic induction of the immunoglobulin germline Calpha promoter Physical interaction of the activator protein-1 factors c-Fos and c-Jun with Cbfa1 for collagenase-3 promoter activation Functional dissection of the alpha and beta subunits of transcription factor PEBP2 and the redox susceptibility of its DNA binding activity Structural basis for the heterodimeric interaction between the acute leukaemia-associated transcription factors AML1 and CBFbeta A RUNX2/PEBP2alpha A/CBFA1 mutation displaying impaired transactivation and Smad interaction in cleidocranial dysplasia CBFA1 Mutation Analysis and Functional Correlation with Phenotypic Variability in Cleidocranial Dysplasia CCAAT/enhancer-binding proteins (C/EBP) beta and delta activate osteocalcin gene transcription and synergize with Runx2 at the C/EBP element to regulate bone-specific expression. Role of Cbfb in hematopoiesis and perturbations resulting from expression of the leukemogenic fusion gene Cbfb-MYH11 Cbfa1 isoforms exert functional differences in osteoblast differentiation Differential regulation of the two principal Runx2/Cbfa1 n-terminal isoforms in response to bone morphogenetic protein-2 during development of the osteoblast phenotype. Core-binding factor beta interacts with Runx2 and is required for skeletal development Core-binding factor beta (CBFbeta), but not CBFbeta-smooth muscle myosin heavy chain, rescues definitive hematopoiesis in CBFbeta-deficient embryonic stem cells The core-binding factor beta subunit is required for bone formation and hematopoietic maturation Expression and regulation of Runx2/Cbfa1 and osteoblast phenotypic markers during the growth and differentiation of human osteoblasts Regulation of the activity of the transcription factor Runx2 by two homeobox proteins, Msx2 and Dlx5
author name string	wds:Q28586662-02743CA6-EEF7-4F4C-8B3F-B2A43C7B3AFC wds:Q28586662-2F9D229E-0236-45A3-B358-087226C61BC9 wds:Q28586662-6BB943EA-46CB-45D6-9F2B-6E65C9C136C6 wds:Q28586662-89216777-E798-4D4B-9403-00891D744377 wds:Q28586662-B36A0685-EDA1-4950-A993-0AFA4FC0B58C wds:Q28586662-D93B32C6-7487-4103-BC37-F8DFA825A7FB wds:Q28586662-EA928E46-5872-43DB-A90C-1F8A54FF5F00 wds:Q28586662-EB5668F4-BE9E-4E86-92CD-32E2475FC151
OpenCitations bibliographic resource ID	wds:Q28586662-CE9A586E-07DC-4CE3-A4BB-AAEC7A8DE7EF
OpenCitations bibliographic resource ID	https://w3id.org/oc/corpus/br/3868989
author name string	P. Paul Liu Yingzi Yang Jane B. Lian Michael Eckhaus Jae-Pil Jeon Alan Horner Glen H. Nuckolls Lillian Shum
OpenCitations bibliographic resource ID	3868989
rdfs:label	Cbfbeta interacts with Runx2 and has a critical role in bone development (en) Cbfbeta interacts with Runx2 and has a critical role in bone development (nl) Cbfbeta interacts with Runx2 and has a critical role in bone development (ast)
skos:prefLabel	Cbfbeta interacts with Runx2 and has a critical role in bone development (en) Cbfbeta interacts with Runx2 and has a critical role in bone development (nl) Cbfbeta interacts with Runx2 and has a critical role in bone development (ast)
name	Cbfbeta interacts with Runx2 and has a critical role in bone development (en) Cbfbeta interacts with Runx2 and has a critical role in bone development (nl)

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