About: Ubiquinone is necessary for mouse embryonic development but is not essential for mitochondrial respiration

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rdf:type	Item
description	artículu científicu espublizáu en 2001 (ast) vědecký článek publikovaný v roce 2001 (cs) наукова стаття, опублікована в грудні 2001 (uk) 2001 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած (hyw) 2001 թվականի դեկտեմբերին հրատարակված գիտական հոդված (hy) wetenschappelijk artikel (gepubliceerd op 2001/12/07) (nl) vedecký článok (publikovaný 2001/12/07) (sk) مقالة علمية (نشرت في 7-12-2001) (ar) article publié dans la revue scientifique Journal of Biological Chemistry (fr) im Dezember 2001 veröffentlichter wissenschaftlicher Artikel (de) scientific journal article (en)
publication date	wds:Q28586387-31D8FD0E-43E1-4462-B8D2-CF4C09796BA3
publication date	2001-12-07 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q28586387-9CFC1854-DD0A-4186-A9C2-18DF6A01D346
language of work or name	English
author name string	wds:Q28586387-19077679-B364-413F-8BAD-36EB739F5CA7 wds:Q28586387-53CC821B-044B-4015-8FF9-1E6ED0965268 wds:Q28586387-675D4862-2226-4DF7-B731-985765CC8125 wds:Q28586387-6BFF994E-4987-44FB-9B75-ABC75F199C08 wds:Q28586387-8DE10DE3-E458-4A0F-B1C4-AC6DF1698632 wds:Q28586387-C839B2DC-B8A6-47FB-A294-DF5CBDAC000D
author name string	E. Shoubridge F. Levavasseur H. Miyadera J. Sirois M. L. Tremblay S. Hekimi
rdfs:label	Ubiquinone is necessary for mouse embryonic development but is not essential for mitochondrial respiration (en) Ubiquinone is necessary for mouse embryonic development but is not essential for mitochondrial respiration (nl) Ubiquinone is necessary for mouse embryonic development but is not essential for mitochondrial respiration (ast)
skos:prefLabel	Ubiquinone is necessary for mouse embryonic development but is not essential for mitochondrial respiration (en) Ubiquinone is necessary for mouse embryonic development but is not essential for mitochondrial respiration (nl) Ubiquinone is necessary for mouse embryonic development but is not essential for mitochondrial respiration (ast)
name	Ubiquinone is necessary for mouse embryonic development but is not essential for mitochondrial respiration (en) Ubiquinone is necessary for mouse embryonic development but is not essential for mitochondrial respiration (nl) Ubiquinone is necessary for mouse embryonic development but is not essential for mitochondrial respiration (ast)
author	wds:Q28586387-F4B764C3-741A-4D7D-8A21-845E91C87C49
author	Kiyoshi Kita
title	wds:Q28586387-31773295-45D6-48BA-A73F-4A5E35E76D81
title	Ubiquinone is necessary for mouse embryonic development but is not essential for mitochondrial respiration (en)
page(s)	wds:Q28586387-0A0AD62E-55F9-4553-AD00-796EEFACAAEA
page(s)	46160–46164
instance of	wds:Q28586387-243B3028-81A2-4CF1-B517-B8EB38917902
instance of	scholarly article
main subject	wds:Q28586387-EFD7798A-2D5B-485C-AC54-F795FF4500BC wds:Q28586387-FE4C6232-37A0-4E94-92CB-5C6DC6403E3C
main subject	mitochondrion Demethyl-Q 7
PubMed ID	wds:Q28586387-C9B670EB-986B-4958-882E-413B4B6A5195
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/11585841
PubMed ID	11585841
published in	wds:Q28586387-12207464-6BF3-4267-B16F-161ED028A293
published in	Journal of Biological Chemistry
issue	wds:Q28586387-00F961C6-5546-4937-9427-0FA3701076F6
volume	wds:Q28586387-CCA050EE-A5C9-4415-8354-D7D4C3C5A87E
issue	49
volume	276
DOI	wds:Q28586387-138BBA0E-60F7-4153-BECC-F7D249A8A478
DOI	http://dx.doi.org/10.1074/JBC.M108980200
DOI	10.1074/JBC.M108980200
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q28586387
is cites work of	Mitochondrial COQ9 is a lipid-binding protein that associates with COQ7 to enable coenzyme Q biosynthesis A nuclear role for the respiratory enzyme CLK-1 in regulating mitochondrial stress responses and longevity Coenzyme Q10 Levels Are Decreased in the Cerebellum of Multiple-System Atrophy Patients. Molecular genetics of ubiquinone biosynthesis in animals An enhanced immune response of Mclk1⁺/⁻ mutant mice is associated with partial protection from fibrosis, cancer and the development of biomarkers of aging. Early mitochondrial dysfunction in long-lived Mclk1+/- mice Mitochondrial oxidative stress alters a pathway in Caenorhabditis elegans strongly resembling that of bile acid biosynthesis and secretion in vertebrates Restoring de novo coenzyme Q biosynthesis in Caenorhabditis elegans coq-3 mutants yields profound rescue compared to exogenous coenzyme Q supplementation Complementation of Escherichia coli ubiF mutation by Caenorhabditis elegans CLK-1, a product of the longevity gene of the nematode worm. Taking a "good" look at free radicals in the aging process Uncoupling the pleiotropic phenotypes of clk-1 with tRNA missense suppressors in Caenorhabditis elegans Sensitivity of Caenorhabditis elegans clk-1 mutants to ubiquinone side-chain length reveals multiple ubiquinone-dependent processes Molecular mechanism of maternal rescue in the clk-1 mutants of Caenorhabditis elegans. The effect of different ubiquinones on lifespan in Caenorhabditis elegans Silencing of ubiquinone biosynthesis genes extends life span inCaenorhabditis elegans Ubiquinone is necessary for Caenorhabditis elegans development at mitochondrial and non-mitochondrial sites. The anti-neurodegeneration drug clioquinol inhibits the aging-associated protein CLK-1. How to live long and prosper: autophagy, mitochondria, and aging Biosynthesis, bioproduction and novel roles of ubiquinone Differential gene expression in human hepatocellular carcinoma Hep3B cells induced by apoptosis-related gene BNIPL-2 The intersection between aging and cardiovascular disease The role of DMQ(9) in the long-lived mutant clk-1. The role of mitochondria in the life of the nematode, Caenorhabditis elegans Tissue-specific oxidative stress and loss of mitochondria in CoQ-deficient Pdss2 mutant mice. Genetics of coenzyme q10 deficiency Altered bacterial metabolism, not coenzyme Q content, is responsible for the lifespan extension in Caenorhabditis elegans fed an Escherichia coli diet lacking coenzyme Q. Public and private mechanisms of life extension in Caenorhabditis elegans Demethoxy-Q, an intermediate of coenzyme Q biosynthesis, fails to support respiration in Saccharomyces cerevisiae and lacks antioxidant activity. Effect of vanillic acid on COQ6 mutants identified in patients with coenzyme Q10 deficiency. Primary coenzyme Q deficiency in Pdss2 mutant mice causes isolated renal disease Longevity in mice: is stress resistance a common factor? CLK-1 protein has DNA binding activity specific to O(L) region of mitochondrial DNA. Reversal of the mitochondrial phenotype and slow development of oxidative biomarkers of aging in long-lived Mclk1+/- mice A mutation in the inner mitochondrial membrane peptidase 2-like gene (Immp2l) affects mitochondrial function and impairs fertility in mice The AtPPT1 gene encoding 4-hydroxybenzoate polyprenyl diphosphate transferase in ubiquinone biosynthesis is required for embryo development in Arabidopsis thaliana The age of heterozygosity. Evolutionary conservation of the clk-1-dependent mechanism of longevity: loss of mclk1 increases cellular fitness and lifespan in mice Development and fertility in Caenorhabditis elegans clk-1 mutants depend upon transport of dietary coenzyme Q8 to mitochondria

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