About: Chronic and acute models of retinal neurodegeneration TrkA activity are neuroprotective whereas p75NTR activity is neurotoxic through a paracrine mechanism

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About: Chronic and acute models of retinal neurodegeneration TrkA activity are neuroprotective whereas p75NTR activity is neurotoxic through a paracrine mechanism Goto Sponge NotDistinct Permalink

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description	artículu científicu espublizáu en 2010 (ast) vědecký článek publikovaný v roce 2010 (cs) 2010 թվականի դեկտեմբերին հրատարակված գիտական հոդված (hy) наукова стаття, опублікована в грудні 2010 (uk) 2010 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած (hyw) vedecký článok (publikovaný 2010/12/10) (sk) wetenschappelijk artikel (gepubliceerd op 2010/12/10) (nl) مقالة علمية (نشرت في 10-12-2010) (ar) article publié dans la revue scientifique Journal of Biological Chemistry (fr) scientific journal article (en) im Dezember 2010 veröffentlichter wissenschaftlicher Artikel (de)
publication date	wds:Q28584166-700D7276-7BB1-4446-B647-A4FC7BD2F93E
publication date	2010-12-10 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q28584166-E6E50BCF-AA24-4F5B-A352-50430C5C0322
language of work or name	English
cites work	wds:Q28584166-03D48045-C445-46D0-A69B-4E8834B7DDE1 wds:Q28584166-1358CED6-A0E1-4C68-BA45-56720F39681E wds:Q28584166-16AE7642-80B2-4E61-81A1-6F86E7E5E4B0 wds:Q28584166-1772DD7E-D594-489A-8923-6005655E6FCD wds:Q28584166-1EEA1AF3-C690-4F96-A9DB-55B8AFBA1EB2 wds:Q28584166-2151A497-59E2-4BA8-B0B8-60D146E93E09 wds:Q28584166-250FAD8F-3C92-4AA3-8894-BABABCF8F12E wds:Q28584166-29FB6EAE-DD2F-4615-9590-91904FF7507C wds:Q28584166-2ABF55A8-69DB-4D7C-886C-2E00FCC789E9 wds:Q28584166-2B8B4A5F-C23E-43A3-B589-C1F3D26E479A wds:Q28584166-366EBC99-FAE1-4ACC-8AA8-F7FEF0603901 wds:Q28584166-46B7B4AF-0259-4AB1-9F03-DE41FC2C5F19 wds:Q28584166-4C18ED94-D273-4F04-AC8A-37836B8D97EA wds:Q28584166-4C584287-2B07-401D-88C0-F1994AF48C9C wds:Q28584166-60A18F49-44D1-4531-8D76-184055D1C5B9 wds:Q28584166-6EC0071A-55E7-4C68-B80D-0199C36AE1C7 wds:Q28584166-72C8650B-5DFA-415B-93B8-3605B9FF4D90 wds:Q28584166-75EF9FEA-7B2E-4DC9-A2AF-3FF45F62EF0D wds:Q28584166-7A567A62-3784-45D5-9008-1569C87F09F5 wds:Q28584166-8023B974-49A2-41A9-B016-E9179D570285 wds:Q28584166-80EB67C2-69F0-469D-9CC7-D2862A159982 wds:Q28584166-842922B2-C4FB-45F1-8E76-DA76AC611282 wds:Q28584166-8819E8D6-4E8B-4687-817B-FC6570CEE453 wds:Q28584166-8E5E03CC-FED2-4DEE-B3F5-6DF64C4CE06C wds:Q28584166-90361BC0-6C6E-4564-BD53-4DCD50C8720F wds:Q28584166-93043920-F08D-45CC-B4EB-FE60D454878C wds:Q28584166-AA89905F-7F62-4DF0-B85A-3673F6A84681 wds:Q28584166-C008C733-A890-4D19-AAEC-D143E52FE22E wds:Q28584166-C8D8BEDC-EAB9-4DB5-B6C7-F1D3C1729196 wds:Q28584166-CC7A61CF-B39A-45E2-BF32-822F2074BDB7 wds:Q28584166-DCCAD6F3-701B-4E65-B261-11566210663A wds:Q28584166-E6322B51-6FC8-4ECA-A580-A9DCFAB62CB1 wds:Q28584166-F04CEB83-BC0A-4874-BE5B-EBEFB06D214D wds:Q28584166-FB77396C-C74D-4448-ABE7-A1862C4BE55B wds:Q28584166-FDC41D24-2D90-427A-B1A1-D413204E20ED wds:Q28584166-FDEB5D09-6798-4FCD-A72D-686FFFBA10DA
cites work	Distinction between differentiation, cell cycle, and apoptosis signals in PC12 cells by the nerve growth factor mutant delta9/13, which is selective for the p75 neurotrophin receptor. Regulation of cell survival by secreted proneurotrophins In glaucoma the upregulated truncated TrkC.T1 receptor isoform in glia causes increased TNF-alpha production, leading to retinal ganglion cell death Three experimental glaucoma models in rats: comparison of the effects of intraocular pressure elevation on retinal ganglion cell size and death. Tumor necrosis factor-alpha mediates oligodendrocyte death and delayed retinal ganglion cell loss in a mouse model of glaucoma. Excitotoxic death of retinal neurons in vivo occurs via a non-cell-autonomous mechanism. Inhibition of p75(NTR) in glia potentiates TrkA-mediated survival of injured retinal ganglion cells Small, nonpeptide p75NTR ligands induce survival signaling and inhibit proNGF-induced death. High throughput quantification of mutant huntingtin aggregates ProNGF induces TNFalpha-dependent death of retinal ganglion cells through a p75NTR non-cell-autonomous signaling pathway Neurobiology of glaucomatous optic neuropathy: diverse cellular events in neurodegeneration and neuroprotection The immune system and glaucoma New paradigms in the mechanisms and management of glaucoma Alpha2-macroglobulin is a mediator of retinal ganglion cell death in glaucoma Biological activity of nerve growth factor precursor is dependent upon relative levels of its receptors Identification of critical residues within the conserved and specificity patches of nerve growth factor leading to survival or differentiation A neurotrophic rationale for the therapy of neurodegenerative disorders An agonistic TrkB mAb causes sustained TrkB activation, delays RGC death, and protects the retinal structure in optic nerve axotomy and in glaucoma Microglia-derived pronerve growth factor promotes photoreceptor cell death via p75 neurotrophin receptor Differential modulation of neuron survival during development by nerve growth factor binding to the p75 neurotrophin receptor Expression of trkA, trkB, and trkC in injured and regenerating retinal ganglion cells of adult rats. Detection of early neuron degeneration and accompanying microglial responses in the retina of a rat model of glaucoma. Method for the noninvasive measurement of intraocular pressure in mice Changes in retinal expression of neurotrophins and neurotrophin receptors induced by ocular hypertension Progressive ganglion cell degeneration precedes neuronal loss in a mouse model of glaucoma Retinal ganglion cells downregulate gene expression and lose their axons within the optic nerve head in a mouse glaucoma model. Roles for the pro-neurotrophin receptor sortilin in neuronal development, aging and brain injury. The patterns of retinal ganglion cell death in hypertensive eyes. Optimal nerve growth factor trophic signals mediated by synergy of TrkA and p75 receptor-specific ligands. Genuine Monovalent Ligands of TrkA Nerve Growth Factor Receptors Reveal a Novel Pharmacological Mechanism of Action Specific transcellular carbocyanine-labelling of rat retinal microglia during injury-induced neuronal degeneration Obstructed axonal transport of BDNF and its receptor TrkB in experimental glaucoma Localization of p75 neurotrophin receptor in the retina of the adult SD rat: an immunocytochemical study at light and electron microscopic levels A TrkA-selective, fast internalizing nerve growth factor-antibody complex induces trophic but not neuritogenic signals Neurotrophic rationale in glaucoma: a TrkA agonist, but not NGF or a p75 antagonist, protects retinal ganglion cells in vivo Programmed cell death of retinal ganglion cells during experimental glaucoma
author name string	wds:Q28584166-08F8C5C1-CD03-4AAD-ABF9-925A34CE6D70 wds:Q28584166-34444A84-472C-403F-A5D5-BBCB381961E0 wds:Q28584166-3601FB10-5110-4F16-B67B-2177DAEA56B7 wds:Q28584166-39DD1BB6-0DD1-4B41-BC8F-1978A470CC33 wds:Q28584166-554DEE36-440C-4407-98F3-29F9079D9B65 wds:Q28584166-7494AAC1-867C-49A1-BDD1-C2921B9486B6 wds:Q28584166-88E59E90-A268-4419-B624-8E04ECA532DA wds:Q28584166-8A42018E-5218-44BC-8F97-1E6199381EC6 wds:Q28584166-9225D27B-AE8E-42BA-A028-C91D60D8F040 wds:Q28584166-D12D6DB3-DCB0-4DBF-860E-7B65CA9B0E46 wds:Q28584166-F2FCA930-2B86-4D2D-AFC2-94A6E35F48F8
OpenCitations bibliographic resource ID	wds:Q28584166-9295D3C9-F326-4C70-9C81-8487C1B127F0

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