About: The WNK1 and WNK4 protein kinases that are mutated in Gordon's hypertension syndrome phosphorylate and activate SPAK and OSR1 protein kinases

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About: The WNK1 and WNK4 protein kinases that are mutated in Gordon's hypertension syndrome phosphorylate and activate SPAK and OSR1 protein kinases Goto Sponge NotDistinct Permalink

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description	article scientifique publié en 2005 (fr) artículu científicu espublizáu en 2005 (ast) vědecký článek publikovaný v roce 2005 (cs) наукова стаття, опублікована в жовтні 2005 (uk) 2005 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած (hyw) 2005 թվականի հոտեմբերին հրատարակված գիտական հոդված (hy) مقالة علمية (نشرت في أكتوبر 2005) (ar) wetenschappelijk artikel (gepubliceerd op 2005/10/01) (nl) vedecký článok (publikovaný 2005/10/01) (sk) scientific journal article (en) im Oktober 2005 veröffentlichter wissenschaftlicher Artikel (de)
publication date	wds:Q28583124-92F48A3A-8CB1-4CCB-8ABD-E96107E1B995
publication date	2005-10-01 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q28583124-1BB76871-1206-4F26-B933-54D35AC4944E
language of work or name	English
cites work	wds:Q28583124-00E444DB-4515-4802-9D74-0DAB69443756 wds:Q28583124-0976E118-0DE7-4961-91E6-D95748EBD0B0 wds:Q28583124-0E32C2C4-6D22-4AD1-8DC7-4ECD3CA72684 wds:Q28583124-17B9AA52-8C20-4E0C-811C-114115283DD8 wds:Q28583124-18819221-5120-4ADB-924F-A7658C91ABE3 wds:Q28583124-1B1215B6-F954-43C4-9B58-A644868C5C59 wds:Q28583124-1DE7578C-436F-4EB5-BAA1-CB422B8D529E wds:Q28583124-1F75F21C-1F67-40DE-B863-B97F39FEE2ED wds:Q28583124-273361AB-982E-4560-A68B-3B6089A0A287 wds:Q28583124-29D6B1A7-A484-4189-BA58-0F620ECB7A39 wds:Q28583124-312FE152-5F74-4BA1-A58C-AE36B5EE8678 wds:Q28583124-3438058C-5557-4A8D-B0DC-C31FEE0089A0 wds:Q28583124-34942F65-7004-4B18-A84B-FC7070740D11 wds:Q28583124-387BFF9A-CE6A-4536-88C2-F39FC4DA4136 wds:Q28583124-448739F5-37F0-4F61-BC66-7638F3E2514B wds:Q28583124-5EE70C02-2153-4BD2-B511-AD269B74B045 wds:Q28583124-6074B848-FB66-4FFE-89C6-29979A2CBA94 wds:Q28583124-62D79E0F-6273-4E15-8EBA-2898AE2C6C68 wds:Q28583124-654D2C25-0D87-4523-8F43-C04C576B9133 wds:Q28583124-6EE12591-D94D-425E-B727-5A0D72101C40 wds:Q28583124-733976B1-164B-4C07-BECF-4AF9125D9103 wds:Q28583124-9AAAC68C-9A6E-4579-B04F-8F0A2E9F7F68 wds:Q28583124-A3849DBF-5E94-44AC-A81F-55CE61804637 wds:Q28583124-B775FF0F-D4BA-4505-877F-953EF356569E wds:Q28583124-BFB346D4-2CC8-428E-85CF-20E1CD5F7718 wds:Q28583124-C762E97F-D343-460A-A8CD-E65860CB1521 wds:Q28583124-C9EF8395-0620-4F15-9E5E-2A2065EBAF47 wds:Q28583124-E563F764-08BB-4CF0-AB19-B11E0344B4F9 wds:Q28583124-EFAD0AC1-0A5D-48E9-8F6E-CBED272CD792 wds:Q28583124-F40BD856-2BF6-49AB-ACD9-17C98B6DC590 wds:Q28583124-FA310186-68EA-4A34-842E-4C3F34BD8280
cites work	Probability-based protein identification by searching sequence databases using mass spectrometry data WNK kinases and the control of blood pressure High-level and high-throughput recombinant protein production by transient transfection of suspension-growing human 293-EBNA1 cells Disease-causing mutant WNK4 increases paracellular chloride permeability and phosphorylates claudins WNK kinases, a novel protein kinase subfamily in multi-cellular organisms WNK4 regulates the balance between renal NaCl reabsorption and K+ secretion WNK1, a novel mammalian serine/threonine protein kinase lacking the catalytic lysine in subdomain II WNK kinases regulate thiazide-sensitive Na-Cl cotransport Mechanisms of WNK1 and WNK4 interaction in the regulation of thiazide-sensitive NaCl cotransport Properties of WNK1 and implications for other family members WNK1 phosphorylates synaptotagmin 2 and modulates its membrane binding Activation of the tumour suppressor kinase LKB1 by the STE20-like pseudokinase STRAD Human hypertension caused by mutations in WNK kinases Role of WNK kinases in regulating tubular salt and potassium transport and in the development of hypertension Identification of protein phosphorylation sites by a combination of mass spectrometry and solid phase Edman sequencing Wnk1 kinase deficiency lowers blood pressure in mice: A gene-trap screen to identify potential targets for therapeutic intervention Humoral immunity to human breast cancer: antigen definition and quantitative analysis of mRNA expression PASK (Proline-Alanine-rich STE20-related Kinase), a Regulatory Kinase of the Na-K-Cl Cotransporter (NKCC1) Characterization of the interaction of the stress kinase SPAK with the Na+-K+-2Cl- cotransporter in the nervous system: evidence for a scaffolding role of the kinase Cation chloride cotransporters interact with the stress-related kinases Ste20-related proline-alanine-rich kinase (SPAK) and oxidative stress response 1 (OSR1) Regulation of diverse ion transport pathways by WNK4 kinase: a novel molecular switch Volume sensitivity of cation-Cl- cotransporters is modulated by the interaction of two kinases: Ste20-related proline-alanine-rich kinase and WNK4. Molecular cloning and characterization of a novel Ste20-related protein kinase enriched in neurons and transporting epithelia MO25alpha/beta interact with STRADalpha/beta enhancing their ability to bind, activate and localize LKB1 in the cytoplasm The kinase DYRK1A phosphorylates the transcription factor FKHR at Ser329 in vitro, a novel in vivo phosphorylation site Isolation and characterization of a novel serine threonine kinase gene on chromosome 3p22-21.3 Regulation of protein kinases; controlling activity through activation segment conformation WNK1, the kinase mutated in an inherited high-blood-pressure syndrome, is a novel PKB (protein kinase B)/Akt substrate Three novel missense mutations of WNK4, a kinase mutated in inherited hypertension, in Japanese hypertensives: implication of clinical phenotypes The Na-K-Cl cotransport protein of shark rectal gland. II. Regulation by direct phosphorylation Characterization of a phosphorylation event resulting in upregulation of the salivary Na(+)-K(+)-2Cl(-) cotransporter
author name string	wds:Q28583124-27127BCA-7849-442F-8391-A011C36BBE1F wds:Q28583124-6ECE9FF7-952A-4CEE-9D75-0A4EB60B0188 wds:Q28583124-76F539FC-5260-4279-9A3F-27328DA1F00C
OpenCitations bibliographic resource ID	wds:Q28583124-8F2EA312-4598-479D-A943-881ED07FE726
OpenCitations bibliographic resource ID	https://w3id.org/oc/corpus/br/4595415
author name string	Dario R. Alessi Alberto C. Vitari Nick A. Morrice
OpenCitations bibliographic resource ID	4595415
rdfs:label	The WNK1 and WNK4 protein kinases that are mutated in Gordon's hypertension syndrome phosphorylate and activate SPAK and OSR1 protein kinases (en) The WNK1 and WNK4 protein kinases that are mutated in Gordon's hypertension syndrome phosphorylate and activate SPAK and OSR1 protein kinases (nl) The WNK1 and WNK4 protein kinases that are mutated in Gordon's hypertension syndrome phosphorylate and activate SPAK and OSR1 protein kinases (ast)
skos:prefLabel	The WNK1 and WNK4 protein kinases that are mutated in Gordon's hypertension syndrome phosphorylate and activate SPAK and OSR1 protein kinases (en) The WNK1 and WNK4 protein kinases that are mutated in Gordon's hypertension syndrome phosphorylate and activate SPAK and OSR1 protein kinases (nl) The WNK1 and WNK4 protein kinases that are mutated in Gordon's hypertension syndrome phosphorylate and activate SPAK and OSR1 protein kinases (ast)
name	The WNK1 and WNK4 protein kinases that are mutated in Gordon's hypertension syndrome phosphorylate and activate SPAK and OSR1 protein kinases (en) The WNK1 and WNK4 protein kinases that are mutated in Gordon's hypertension syndrome phosphorylate and activate SPAK and OSR1 protein kinases (nl) The WNK1 and WNK4 protein kinases that are mutated in Gordon's hypertension syndrome phosphorylate and activate SPAK and OSR1 protein kinases (ast)
author	wds:Q28583124-19DA6F65-695F-4C41-8C5F-FE1775075175
author	Maria Deak
title	wds:Q28583124-B21FB23C-4022-4E7B-AE5F-9B7A506D10D7
title	The WNK1 and WNK4 protein kinases that are mutated in Gordon's hypertension syndrome phosphorylate and activate SPAK and OSR1 protein kinases (en)

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