About: Double-stranded RNA induces pancreatic beta-cell apoptosis by activation of the toll-like receptor 3 and interferon regulatory factor 3 pathways

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scientific journal article

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rdf:type	Item
description	artículu científicu espublizáu en 2008 (ast) vědecký článek publikovaný v roce 2008 (cs) 2008 թվականի մայիսին հրատարակված գիտական հոդված (hy) наукова стаття, опублікована в травні 2008 (uk) 2008 թուականի Մայիսին հրատարակուած գիտական յօդուած (hyw) مقالة علمية (نشرت في مايو 2008) (ar) vedecký článok (publikovaný 2008/05/01) (sk) wetenschappelijk artikel (gepubliceerd op 2008/05/01) (nl) im Mai 2008 veröffentlichter wissenschaftlicher Artikel (de) scientific journal article (en)
publication date	wds:Q28579715-92A7A7C9-6709-41AA-869F-FB6B698F9AD2
publication date	2008-05-01 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q28579715-C5AC21A9-9E14-4925-AC85-5BB6DEE6DEEE
language of work or name	English
author name string	wds:Q28579715-05DB11F6-D26F-4D81-BE72-C87E607C7F6E wds:Q28579715-05E3C350-F6CE-49F2-8808-C7E37AB7883E wds:Q28579715-0A89652E-2958-42F5-96AE-B739E2E9B0E6 wds:Q28579715-1E1DB4C8-F283-45F9-86D6-9DDCABA2E481 wds:Q28579715-5811F61B-0FEA-43D8-96E4-C1A8F7B8895E wds:Q28579715-DD088578-7AF9-4E54-84BE-81F01B927545 wds:Q28579715-FED3E692-F4FD-48F6-A475-9C5D2436E184
OpenCitations bibliographic resource ID	wds:Q28579715-FC0A1F10-FB84-4C48-AFBD-9E0E757FE09A
OpenCitations bibliographic resource ID	https://w3id.org/oc/corpus/br/4161119
author name string	Daisy Flamez Conny Gysemans Decio L. Eizirik Joanne Rasschaert Michel Goldman Mónica García Zeynep Dogusan
OpenCitations bibliographic resource ID	4161119
rdfs:label	Double-stranded RNA induces pancreatic beta-cell apoptosis by activation of the toll-like receptor 3 and interferon regulatory factor 3 pathways (en) Double-stranded RNA induces pancreatic beta-cell apoptosis by activation of the toll-like receptor 3 and interferon regulatory factor 3 pathways (nl) Double-stranded RNA induces pancreatic beta-cell apoptosis by activation of the toll-like receptor 3 and interferon regulatory factor 3 pathways (ast)
skos:prefLabel	Double-stranded RNA induces pancreatic beta-cell apoptosis by activation of the toll-like receptor 3 and interferon regulatory factor 3 pathways (en) Double-stranded RNA induces pancreatic beta-cell apoptosis by activation of the toll-like receptor 3 and interferon regulatory factor 3 pathways (nl) Double-stranded RNA induces pancreatic beta-cell apoptosis by activation of the toll-like receptor 3 and interferon regulatory factor 3 pathways (ast)
name	Double-stranded RNA induces pancreatic beta-cell apoptosis by activation of the toll-like receptor 3 and interferon regulatory factor 3 pathways (en) Double-stranded RNA induces pancreatic beta-cell apoptosis by activation of the toll-like receptor 3 and interferon regulatory factor 3 pathways (nl) Double-stranded RNA induces pancreatic beta-cell apoptosis by activation of the toll-like receptor 3 and interferon regulatory factor 3 pathways (ast)
author	wds:Q28579715-44E9B0E3-FC78-4EFA-89A8-DC52DB91AA67 wds:Q28579715-8BD63179-1C8E-4A54-96C4-92B1FA5FD549 wds:Q28579715-D01F97C1-679A-4AB2-9484-13A51CF78C9C
author	Chantal Mathieu Claude Libert Lena Alexopoulou
title	wds:Q28579715-226F26F6-4C1B-427D-AB4A-5A7E33AC9AAD
title	Double-stranded RNA induces pancreatic beta-cell apoptosis by activation of the toll-like receptor 3 and interferon regulatory factor 3 pathways (en)
page(s)	wds:Q28579715-07680C06-7F66-42E5-9507-E396F6350B4D
page(s)	1236–1245
instance of	wds:Q28579715-1246FDB0-C59D-4EE6-B2A5-28DDECFF6579
instance of	scholarly article
main subject	wds:Q28579715-400EAAB7-1D60-4885-99A4-3A73C5A0E439 wds:Q28579715-BBB557FA-6155-4D25-A02B-A4A4AA92AFCA
main subject	toll-like receptor apoptotic process
PubMed ID	wds:Q28579715-9E7577EA-B8CB-456F-BA93-E567F812930A
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/18223009
PubMed ID	18223009
published in	wds:Q28579715-4BAB07AB-24FE-4942-B201-75192C6D65F2
published in	Diabetes
issue	wds:Q28579715-B89424D4-54ED-4322-A6C5-7D74C15974E1
volume	wds:Q28579715-BD33CD6F-CD39-42FC-8039-66FF30399659
issue	5
volume	57
DOI	wds:Q28579715-F10C224D-ACA2-44E6-B09B-25D125662D54
DOI	http://dx.doi.org/10.2337/DB07-0844
DOI	10.2337/DB07-0844
ResearchGate publication ID	wds:Q28579715-C531F3BC-66BD-4585-BA27-830ABA741625
ResearchGate publication ID	5628836
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q28579715
is cites work of	Function and regulation of retinoic acid-inducible gene-I Exposure to the viral by-product dsRNA or Coxsackievirus B5 triggers pancreatic beta cell apoptosis via a Bim / Mcl-1 imbalance Modulation of innate immunity in human pancreatic islets infected with enterovirus in vitro Pathogenesis of type 1 diabetes mellitus: interplay between enterovirus and host The beta-cell in type 1 diabetes: What have we learned from proteomic studies? Expression of innate immunity genes and damage of primary human pancreatic islets by epidemic strains of Echovirus: implication for post-virus islet autoimmunity. Examination of a Viral Infection Mimetic Model in Human iPS Cell-Derived Insulin-Producing Cells and the Anti-Apoptotic Effect of GLP-1 Analogue MDA5 and PTPN2, two candidate genes for type 1 diabetes, modify pancreatic beta-cell responses to the viral by-product double-stranded RNA. The role of inflammation in insulitis and beta-cell loss in type 1 diabetes Attenuation of the influenza virus sickness behavior in mice deficient in Toll-like receptor 3 Innate immunity and the pathogenesis of type 1 diabetes. Induction of innate immune response through TLR2 and dectin 1 prevents type 1 diabetes. Toll-like receptor 3 (TLR3) induces apoptosis via death receptors and mitochondria by up-regulating the transactivating p63 isoform alpha (TAP63alpha). Short-interfering RNAs induce retinal degeneration via TLR3 and IRF3. Uterine epithelial cells specifically induce interferon-stimulated genes in response to polyinosinic-polycytidylic acid independently of estradiol The multiple facets of toll-like receptors in transplantation biology Candidate genes for type 1 diabetes modulate pancreatic islet inflammation and β-cell apoptosis Trappin-2/elafin modulate innate immune responses of human endometrial epithelial cells to PolyI:C Synergy between RA and TLR3 promotes type I IFN-dependent apoptosis through upregulation of TRAIL pathway in breast cancer cells TLR3 signaling is either protective or pathogenic for the development of Theiler's virus-induced demyelinating disease depending on the time of viral infection ERK pathway and sheddases play an essential role in ethanol-induced CX3CL1 release in pancreatic stellate cells. Phenylmethimazole suppresses dsRNA-induced cytotoxicity and inflammatory cytokines in murine pancreatic beta cells and blocks viral acceleration of type 1 diabetes in NOD mice. Double-stranded RNAs containing multiple IU pairs are sufficient to suppress interferon induction and apoptosis Toll-like receptor 3 (TLR3) and the development of type 1 diabetes mellitus. Group B coxsackieviruses and autoimmunity: focus on Type 1 diabetes. Immunology in the clinic review series; focus on type 1 diabetes and viruses: how viral infections modulate beta cell function Rotavirus infection induces transient pancreatic involution and hyperglycemia in weanling mice The pancreatic β cell and type 1 diabetes: innocent bystander or active participant?

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