About: Mixed lineage kinase 3 (MLK3)-activated p38 MAP kinase mediates transforming growth factor-beta-induced apoptosis in hepatoma cells

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Mixed lineage kinase 3 (MLK3)-activated p38 MAP kinase mediates transforming growth factor-beta-induced apoptosis in hepatoma cells Goto Sponge NotDistinct Permalink

An Entity of Type : wikibase:Item, within Data Space : wikidata.demo.openlinksw.com associated with source document(s)

scientific journal article

Attributes	Values
rdf:type	Item
description	artículu científicu espublizáu en 2004 (ast) vědecký článek publikovaný v roce 2004 (cs) 2004 թուականի Յուլիսին հրատարակուած գիտական յօդուած (hyw) наукова стаття, опублікована в липні 2004 (uk) 2004 թվականի հուլիսին հրատարակված գիտական հոդված (hy) vedecký článok (publikovaný 2004/07/09) (sk) مقالة علمية (نشرت في 9-7-2004) (ar) article publié dans la revue scientifique Journal of Biological Chemistry (fr) scientific journal article (en) im Juli 2004 veröffentlichter wissenschaftlicher Artikel (de) wetenschappelijk artikel (gepubliceerd op 2004/07/09) (nl)
publication date	wds:Q28578617-8E5B7B09-C605-4E44-9806-93A4F4629725
publication date	2004-07-09 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q28578617-B52C5C78-3048-4E62-9A19-54EB425CD766
language of work or name	English
cites work	wds:Q28578617-03AD6E65-676A-4605-88B9-CFC8DF31B9FF wds:Q28578617-07173201-0F0E-4224-8962-1706E761307F wds:Q28578617-08815534-5883-44D9-A71B-855134326196 wds:Q28578617-0950DD6E-A2E3-46EF-9E2C-290DE6D6F159 wds:Q28578617-0BB0866D-1574-4CC9-8CF0-FBCF6E089EBC wds:Q28578617-0BF671E6-8FB4-43A8-8FF4-267A58959826 wds:Q28578617-0DC798F9-E2ED-416A-BC2B-E72F6F015085 wds:Q28578617-0EABFD39-E17C-4A20-9FBC-12C54B38EDBD wds:Q28578617-10ED845B-8627-411F-9D80-F6EF5329E2F0 wds:Q28578617-1E84DE31-2FCB-4782-9A5E-8757616B8AED wds:Q28578617-29D03628-B86F-451C-AC09-B841722CF9A3 wds:Q28578617-349FC3F7-15DD-4C7D-BFE5-345904318F18 wds:Q28578617-444C8924-390A-4D5D-B362-C7A9955543C6 wds:Q28578617-49A8D2EE-5715-4473-B24B-A5F09C22A857 wds:Q28578617-4FBB8770-9F7E-4886-9F9A-6E03CAF09A68 wds:Q28578617-74D3847D-E405-486D-89EE-4C55F39CBB9E wds:Q28578617-7917F070-00B7-451A-8AFC-822444D7B665 wds:Q28578617-79F367E6-66C8-48B0-B84D-BABA6EC4DEDD wds:Q28578617-863DFE58-C3BB-4EDC-8DC4-308363C64886 wds:Q28578617-875780FC-CE27-46E1-9586-4E6D1CA41575 wds:Q28578617-93AA9292-93F6-45E6-8EB7-3663454AEFD6 wds:Q28578617-98D786C6-F9D6-4014-BD81-46EBBD44D101 wds:Q28578617-9D81C3E2-BAF0-4CEC-AD47-5A88529A1D73 wds:Q28578617-B30DFF5D-F16C-489F-BCFC-02F39815B5E5 wds:Q28578617-BF55F00D-178A-4915-97D9-BC4CB5846762 wds:Q28578617-CF9BC96A-D9DB-480B-A3DE-6DE3E528DB29 wds:Q28578617-D2671777-31DB-4223-AD87-7AA96474C0EB wds:Q28578617-D5AEB603-4193-48E7-B1BA-7CC410720604 wds:Q28578617-D89CA826-E3CF-4A97-80A4-CC01A168D20E wds:Q28578617-E353CA20-CA25-44D5-87CC-E0C5A1F2DFD4 wds:Q28578617-F739639F-B8FC-4661-81F5-67DD3141ADF3
cites work	A conserved binding motif defines numerous candidate target proteins for both Cdc42 and Rac GTPases Cdc42-induced activation of the mixed-lineage kinase SPRK in vivo. Requirement of the Cdc42/Rac interactive binding motif and changes in phosphorylation Mixed-lineage kinase control of JNK and p38 MAPK pathways Zipper-mediated oligomerization of the mixed lineage kinase SPRK/MLK-3 is not required for its activation by the GTPase cdc 42 but Is necessary for its activation of the JNK pathway. Monomeric SPRK L410P does not catalyze the activating phosphorylat Cross-talk between JNK/SAPK and ERK/MAPK pathways: sustained activation of JNK blocks ERK activation by mitogenic factors TGF-beta-induced apoptosis is mediated by the adapter protein Daxx that facilitates JNK activation Complete nucleotide sequence, expression, and chromosomal localisation of human mixed-lineage kinase 2 The MAP kinase kinase kinase MLK2 co-localizes with activated JNK along microtubules and associates with kinesin superfamily motor KIF3 MST/MLK2, a member of the mixed lineage kinase family, directly phosphorylates and activates SEK1, an activator of c-Jun N-terminal kinase/stress-activated protein kinase The mixed lineage kinase SPRK phosphorylates and activates the stress-activated protein kinase activator, SEK-1. Mitogen-activated protein kinase pathways Role of MAP kinases and their cross-talk in TGF-beta1-induced apoptosis in FaO rat hepatoma cell line Transforming growth factor beta 1 induces apoptosis through cleavage of BAD in a Smad3-dependent mechanism in FaO hepatoma cells Identification of in vivo phosphorylation sites of MLK3 by mass spectrometry and phosphopeptide mapping Transforming growth factor-beta-induced apoptosis is mediated by Smad-dependent expression of GADD45b through p38 activation Caspase cleavage enhances the apoptosis-inducing effects of BAD. Cdc2 and Cdk2 kinase activated by transforming growth factor-beta1 trigger apoptosis through the phosphorylation of retinoblastoma protein in FaO hepatoma cells ICE-like protease (caspase) is involved in transforming growth factor beta1-mediated apoptosis in FaO rat hepatoma cell line Fibroblast growth factor-2 suppression of tumor necrosis factor alpha-mediated apoptosis requires Ras and the activation of mitogen-activated protein kinase Extracellular signal-regulated kinase (ERK) activity is required for TPA-mediated inhibition of drug-induced apoptosis. Cardiotrophin 1 (CT-1) inhibition of cardiac myocyte apoptosis via a mitogen-activated protein kinase-dependent pathway. Divergence from downstream CT-1 signals for myocardial cell hypertrophy Transcriptional control by the TGF-beta/Smad signaling system The MLK family mediates c-Jun N-terminal kinase activation in neuronal apoptosis SEK1 deficiency reveals mitogen-activated protein kinase cascade crossregulation and leads to abnormal hepatogenesis Human Smad3 and Smad4 are sequence-specific transcription activators SP600125, an anthrapyrazolone inhibitor of Jun N-terminal kinase Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis Smads as transcriptional co-modulators Molecular cloning and functional expression of a cDNA encoding a new member of mixed lineage protein kinase from human brain Identification of a new family of human epithelial protein kinases containing two leucine/isoleucine-zipper domains Requirement of TGF-beta receptor-dependent activation of c-Jun N-terminal kinases (JNKs)/stress-activated protein kinases (Sapks) for TGF-beta up-regulation of the urokinase-type plasminogen activator receptor.
author name string	wds:Q28578617-4E1945C0-A2F9-4E67-A521-3D05F65BC990 wds:Q28578617-7A04F8F2-76F3-437A-AB4C-19F3631A5078 wds:Q28578617-CEF4AA4D-A1D0-43F8-8F20-FF92A293C49E wds:Q28578617-FA781AD3-90DB-46AD-BBAE-1DB1FFC015F4
OpenCitations bibliographic resource ID	wds:Q28578617-AAEB638C-E13E-4123-993D-FB9A436B691D
OpenCitations bibliographic resource ID	https://w3id.org/oc/corpus/br/1493813
author name string	Seong-Jin Kim Zhiheng Xu Byung-Chul Kim Ki-Yong Kim
OpenCitations bibliographic resource ID	1493813
rdfs:label	Mixed lineage kinase 3 (MLK3)-activated p38 MAP kinase mediates transforming growth factor-beta-induced apoptosis in hepatoma cells (en) Mixed lineage kinase 3 (MLK3)-activated p38 MAP kinase mediates transforming growth factor-beta-induced apoptosis in hepatoma cells (nl) Mixed lineage kinase 3 (MLK3)-activated p38 MAP kinase mediates transforming growth factor-beta-induced apoptosis in hepatoma cells (ast)
skos:prefLabel	Mixed lineage kinase 3 (MLK3)-activated p38 MAP kinase mediates transforming growth factor-beta-induced apoptosis in hepatoma cells (en) Mixed lineage kinase 3 (MLK3)-activated p38 MAP kinase mediates transforming growth factor-beta-induced apoptosis in hepatoma cells (nl) Mixed lineage kinase 3 (MLK3)-activated p38 MAP kinase mediates transforming growth factor-beta-induced apoptosis in hepatoma cells (ast)
name	Mixed lineage kinase 3 (MLK3)-activated p38 MAP kinase mediates transforming growth factor-beta-induced apoptosis in hepatoma cells (en) Mixed lineage kinase 3 (MLK3)-activated p38 MAP kinase mediates transforming growth factor-beta-induced apoptosis in hepatoma cells (nl) Mixed lineage kinase 3 (MLK3)-activated p38 MAP kinase mediates transforming growth factor-beta-induced apoptosis in hepatoma cells (ast)
title	wds:Q28578617-FCF13F78-9F12-43F2-AAC7-9923433B8B2B
title	Mixed lineage kinase 3 (MLK3)-activated p38 MAP kinase mediates transforming growth factor-beta-induced apoptosis in hepatoma cells (en)

Faceted Search & Find service v1.16.117 as of May 05 2024

Alternative Linked Data Documents: ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3239 as of May 5 2024, on Linux (x86_64-centos_6-linux-gnu), Single-Server Edition (378 GB total memory, 180 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2025 OpenLink Software