About: Enhanced rat beta-cell proliferation in 60% pancreatectomized islets by increased glucose metabolic flux through pyruvate carboxylase pathway

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description	article scientifique publié en 2005 (fr) artículu científicu espublizáu en 2005 (ast) vědecký článek publikovaný v roce 2005 (cs) 2005 թվականի մարտին հրատարակված գիտական հոդված (hy) 2005 թուականի Մարտին հրատարակուած գիտական յօդուած (hyw) наукова стаття, опублікована в березні 2005 (uk) مقالة علمية (نشرت في مارس 2005) (ar) vedecký článok (publikovaný 2005/03/01) (sk) wetenschappelijk artikel (gepubliceerd op 2005/03/01) (nl) im März 2005 veröffentlichter wissenschaftlicher Artikel (de) scientific journal article (en)
publication date	wds:Q28577833-BB9E8AA9-2C87-40D7-9693-01964350C401
publication date	2005-03-01 00:00:00Z (xsd:dateTime)
cites work	wds:Q28577833-0B4D0F77-6199-4E63-AC3C-A3DC18234A5D wds:Q28577833-18ADE2FF-CB36-4F40-8F59-61E2B21671B5 wds:Q28577833-19080C81-D019-4530-BA8D-DA3E58CE6E31 wds:Q28577833-261A1492-C7EC-452A-9932-BA51135CA967 wds:Q28577833-3539F413-3E83-4A83-B953-7A7F3460D79B wds:Q28577833-365D99E1-0A74-4A50-9EA2-B144B2A1CE18 wds:Q28577833-3B223884-2293-4F84-904A-7C9BD20D663E wds:Q28577833-3EBFDFB1-2941-42AD-A1EF-3775E0D46AA5 wds:Q28577833-47B4DD0B-6F37-4749-9F5B-33DA69C1B4AE wds:Q28577833-4B2DE889-5AF8-40A6-BC7D-A59FE137E5EC wds:Q28577833-50591899-F3E0-4D00-B442-DE9220AB1F4C wds:Q28577833-5CCF2771-9207-4A46-9761-6373E0E9E6A1 wds:Q28577833-627F71FB-A9B8-4092-AC4E-64296BE694C1 wds:Q28577833-6FD5555A-8F53-4A49-81BB-302865EC3EA0 wds:Q28577833-7094B435-8E9C-4611-B0CE-6984678A5083 wds:Q28577833-76BFB352-2990-4A7A-9D64-23275AD650BF wds:Q28577833-795DAA84-AE52-465F-A930-A6354FCCFAE9 wds:Q28577833-7D245C7E-1D75-4BAA-A8F8-279E5DFB00C7 wds:Q28577833-80D8B548-C1E5-48BE-B522-F71D4B193BC5 wds:Q28577833-84FE53E2-3B6E-4D76-AD3D-99DDFF234CA1 wds:Q28577833-893ABDC9-B791-467A-94BB-759D91ABD792 wds:Q28577833-98B8D619-B8F8-4EE0-99BD-EA5FCEF5A6E5 wds:Q28577833-9C5FD30C-7B7C-4219-9263-37F5B5B10EE6 wds:Q28577833-A827389F-E1B3-423D-89C0-B2D9F27623E9 wds:Q28577833-B05E647A-7451-4B6B-9EE9-972725512EC5 wds:Q28577833-CC78190F-4BA2-4F0B-94C5-C6D501C42473 wds:Q28577833-D4C3B546-843E-4805-A311-E93933F1B6F7 wds:Q28577833-E1FED6EE-4B2B-4B55-A887-4663691206B3 wds:Q28577833-E97FC5E0-CE7B-408E-8D30-7871782AF908 wds:Q28577833-EA48EEDA-C7FD-4D77-B230-6CB368434E10 wds:Q28577833-EDFEBD44-F222-4324-A5F0-F929139743A3 wds:Q28577833-F54BDEDE-0497-4B7B-9D31-0C2E3140C5F9 wds:Q28577833-F6AB1A53-9FB2-4252-889A-DF033163AC71 wds:Q28577833-F79F47A7-EA6C-4B93-94B9-C13A9EF09651 wds:Q28577833-FF85F4A1-A445-4F97-AF3A-37EB3A9FC9C3
cites work	Severe diabetes, age-dependent loss of adipose tissue, and mild growth deficiency in mice lacking Akt2/PKB beta Overexpression of monocarboxylate transporter and lactate dehydrogenase alters insulin secretory responses to pyruvate and lactate in beta cells Analysis of the putative role of 24-carbon polyunsaturated fatty acids in the biosynthesis of docosapentaenoic (22:5n-6) and docosahexaenoic (22:6n-3) acids Glucose-regulated anaplerosis and cataplerosis in pancreatic beta-cells: possible implication of a pyruvate/citrate shuttle in insulin secretion Export of metabolites from pancreatic islet mitochondria as a means to study anaplerosis in insulin secretion Chronic high glucose lowers pyruvate dehydrogenase activity in islets through enhanced production of long chain acyl-CoA: prevention of impaired glucose oxidation by enhanced pyruvate recycling through the malate-pyruvate shuttle Neuronal death in cultured murine cortical cells is induced by inhibition of GAPDH and triosephosphate isomerase. Regulation of pancreatic beta-cell growth and survival by the serine/threonine protein kinase Akt1/PKBalpha Pancreatic beta-cell-specific targeted disruption of glucokinase gene. Diabetes mellitus due to defective insulin secretion to glucose Pancreatic beta-cell glucokinase: closing the gap between theoretical concepts and experimental realities. A P387L variant in protein tyrosine phosphatase-1B (PTP-1B) is associated with type 2 diabetes and impaired serine phosphorylation of PTP-1B in vitro 13C NMR isotopomer analysis reveals a connection between pyruvate cycling and glucose-stimulated insulin secretion (GSIS) 13C NMR isotopomer analysis of anaplerotic pathways in INS-1 cells DNA sequences in chromosomes II and VII code for pyruvate carboxylase isoenzymes in Saccharomyces cerevisiae: analysis of pyruvate carboxylase-deficient strains. Regulation of pancreatic beta-cell glucokinase: from basics to therapeutics Expression and regulation of glucokinase in rat islet beta- and alpha-cells during development. A simple, rapid, and sensitive DNA assay procedure beta-Cell adaptation to insulin resistance. Increased pyruvate carboxylase and malate-pyruvate shuttle activity in islets of nondiabetic Zucker fatty rats Genetic regulation of metabolic pathways in beta-cells disrupted by hyperglycemia Critical reduction in beta-cell mass results in two distinct outcomes over time. Adaptation with impaired glucose tolerance or decompensated diabetes Identification of carboxylation enzymes and characterization of a novel four-subunit pyruvate:flavodoxin oxidoreductase from Helicobacter pylori Pyruvate carboxylase from Corynebacterium glutamicum: characterization, expression and inactivation of the pyc gene. Regulation of PDH activity and isoform expression: diet and exercise Minimal chronic hyperglycemia is a critical determinant of impaired insulin secretion after an incomplete pancreatectomy Overexpression of lactate dehydrogenase A attenuates glucose-induced insulin secretion in stable MIN-6 beta-cell lines Normalization by insulin treatment of low mitochondrial glycerol phosphate dehydrogenase and pyruvate carboxylase in pancreatic islets of the GK rat. Low mitochondrial glycerol phosphate dehydrogenase and pyruvate carboxylase in pancreatic islets of Zucker diabetic fatty rats In vitro and in vivo suppression of gluconeogenesis by inhibition of pyruvate carboxylase Effects of tungstate, a new potential oral antidiabetic agent, in Zucker diabetic fatty rats. Increased islet DNA synthesis and glucose-derived lipid and amino acid production in association with beta-cell hyperproliferation in normoglycaemic 60 % pancreatectomy rats A model of the pentose phosphate pathway in rat liver cells. Insulin effect during embryogenesis determines fetal growth: a possible molecular link between birth weight and susceptibility to type 2 diabetes. Regulation of the tricarboxylic acid cycle pool size in heart muscle. beta-cell adaptation in 60% pancreatectomy rats that preserves normoinsulinemia and normoglycemia Glucose-fatty acid cycle to inhibit glucose utilization and oxidation is not operative in fatty acid-cultured islets
author name string	wds:Q28577833-5AD58382-E40B-46FF-BBEF-72A6F9092296 wds:Q28577833-CD01D6FE-E519-47DB-A886-65A35B057E28 wds:Q28577833-D3D492A4-1DCB-40F0-9DE2-79FEA5A420E8 wds:Q28577833-EA39A3E9-0E75-48C7-B97C-2C2BFAD8C319
author name string	J. Han P. N. Epstein Y. Q. Liu Y. S. Long
rdfs:label	Enhanced rat beta-cell proliferation in 60% pancreatectomized islets by increased glucose metabolic flux through pyruvate carboxylase pathway (en) Enhanced rat beta-cell proliferation in 60% pancreatectomized islets by increased glucose metabolic flux through pyruvate carboxylase pathway (nl) Enhanced rat beta-cell proliferation in 60% pancreatectomized islets by increased glucose metabolic flux through pyruvate carboxylase pathway (ast)
skos:prefLabel	Enhanced rat beta-cell proliferation in 60% pancreatectomized islets by increased glucose metabolic flux through pyruvate carboxylase pathway (en) Enhanced rat beta-cell proliferation in 60% pancreatectomized islets by increased glucose metabolic flux through pyruvate carboxylase pathway (nl) Enhanced rat beta-cell proliferation in 60% pancreatectomized islets by increased glucose metabolic flux through pyruvate carboxylase pathway (ast)
name	Enhanced rat beta-cell proliferation in 60% pancreatectomized islets by increased glucose metabolic flux through pyruvate carboxylase pathway (en) Enhanced rat beta-cell proliferation in 60% pancreatectomized islets by increased glucose metabolic flux through pyruvate carboxylase pathway (nl)

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