About: Downregulation of cytosolic prostaglandin E2 synthase results in decreased nociceptive behavior in rats

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About: Downregulation of cytosolic prostaglandin E2 synthase results in decreased nociceptive behavior in rats Goto Sponge NotDistinct Permalink

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description	artículu científicu espublizáu en 2005 (ast) vědecký článek publikovaný v roce 2005 (cs) 2005 թվականի սեպտեմբերին հրատարակված գիտական հոդված (hy) наукова стаття, опублікована у вересні 2005 (uk) 2005 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած (hyw) vedecký článok (publikovaný 2005/09/28) (sk) مقالة علمية (نشرت في 28-9-2005) (ar) wetenschappelijk artikel (gepubliceerd op 2005/09/28) (nl) im September 2005 veröffentlichter wissenschaftlicher Artikel (de) scientific journal article (en)
publication date	wds:Q28574729-1459F91C-DD8C-4CBE-BACB-95B0C568B7E1
publication date	2005-09-01 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q28574729-FA44CD06-7567-4A21-AE93-8DF9DC079DED
language of work or name	English
cites work	wds:Q28574729-0C5F77CD-1677-422A-BD3F-3D94ECEF2095 wds:Q28574729-0DAD3F15-D860-4A2C-B0D1-FDA5DF808CAD wds:Q28574729-0DFF330C-9798-46DB-BEC9-85F7EAFDB6A1 wds:Q28574729-1568210F-10A1-44CE-A222-0CFEB07AE952 wds:Q28574729-196F725D-EAB6-4F55-85ED-52C016DD74C7 wds:Q28574729-1C532073-98AA-416B-B42C-927B84D6363C wds:Q28574729-23831C12-56F7-4BA9-9EC5-AD035DCCCAC5 wds:Q28574729-26B2FCC3-5E1E-43C3-B8F6-3336068E849A wds:Q28574729-2A03FACD-FF1F-4770-9090-E1F5EF8CC453 wds:Q28574729-37893064-064A-47A1-9FA6-06908A5DCA10 wds:Q28574729-3D0FB851-488A-417C-BE85-7A3C4CE738DF wds:Q28574729-4909B5A8-9A6B-43D2-977D-5488A8646C2F wds:Q28574729-4BCD68FE-C9D8-4E14-8BA4-95923089C1AE wds:Q28574729-4D76FD62-2151-498F-884C-A84625C2E20B wds:Q28574729-52AA578E-E3F4-4EB3-83F0-BA90224570CD wds:Q28574729-5AE25168-4724-43C5-BBC1-279E6EB3B92C wds:Q28574729-6CF4AA6C-85B4-43FD-BCC0-67F122A24165 wds:Q28574729-6DB4A8B4-6ACD-4F20-B830-E1C5822D35CD wds:Q28574729-7177B88E-47C0-49BA-B8F2-1F0593F5857B wds:Q28574729-7482BC84-9CC3-4345-A277-857282839FC9 wds:Q28574729-8E89F537-EC28-4DDC-BB62-A86CAB47ABD3 wds:Q28574729-91BA4860-2AEE-4B5D-B408-91A144B26E5F wds:Q28574729-94F2B278-9AEC-4757-9CE7-554933FD6D65 wds:Q28574729-9B6DF4A7-3C9E-4060-898B-84E699EE9E9F wds:Q28574729-A2C12EC0-F4D9-421B-943C-C10B87CB94BF wds:Q28574729-A61B4F59-687B-475B-96BC-9C2944D0FDF5 wds:Q28574729-AC0E278D-A51F-4B94-AC79-12E352A206DC wds:Q28574729-D2EE69F7-CD55-47C3-968E-C8BF7812B20C wds:Q28574729-E216F825-9733-4320-812A-2D2B97CDF13B wds:Q28574729-E3046D90-6AA9-4F7A-B57D-2C23CF8285E6 wds:Q28574729-F851285F-FA65-4795-862B-CDD9599C7ABF wds:Q28574729-FA29A4F1-0025-49CA-BD6D-C2752BB802C0
cites work	Prostaglandins and cyclooxygenases [correction of cycloxygenases] in the spinal cord Carrageenan-induced paw edema in rat elicits a predominant prostaglandin E2 (PGE2) response in the central nervous system associated with the induction of microsomal PGE2 synthase-1 Microsomal prostaglandin E synthase-1 is the central switch during immune-induced pyresis Deletion of microsomal prostaglandin E2 (PGE2) synthase-1 reduces inducible and basal PGE2 production and alters the gastric prostanoid profile Reduced pain hypersensitivity and inflammation in mice lacking microsomal prostaglandin e synthase-1. A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia Identification of human prostaglandin E synthase: a microsomal, glutathione-dependent, inducible enzyme, constituting a potential novel drug target Molecular identification of cytosolic prostaglandin E2 synthase that is functionally coupled with cyclooxygenase-1 in immediate prostaglandin E2 biosynthesis Regulation of prostaglandin E2 biosynthesis by inducible membrane-associated prostaglandin E2 synthase that acts in concert with cyclooxygenase-2 Direct activation of rat spinal dorsal horn neurons by prostaglandin E2. Cyclooxygenases: structural, cellular, and molecular biology Impaired inflammatory and pain responses in mice lacking an inducible prostaglandin E synthase Nociception in cyclooxygenase isozyme-deficient mice Inflammatory response: pathway across the blood-brain barrier. Pharmacological analysis of cyclooxygenase-1 in inflammation Recent advances in molecular biology and physiology of the prostaglandin E2-biosynthetic pathway Inhibition of cyclooxygenase-2 rapidly reverses inflammatory hyperalgesia and prostaglandin E2 production The acute antihyperalgesic action of nonsteroidal, anti-inflammatory drugs and release of spinal prostaglandin E2 is mediated by the inhibition of constitutive spinal cyclooxygenase-2 (COX-2) but not COX-1. Changes in the effect of spinal prostaglandin E2 during inflammation: prostaglandin E (EP1-EP4) receptors in spinal nociceptive processing of input from the normal or inflamed knee joint. Interleukin-1beta-mediated induction of Cox-2 in the CNS contributes to inflammatory pain hypersensitivity Release of glutamate, nitric oxide and prostaglandin E2 and metabolic activity in the spinal cord of rats following peripheral nociceptive stimulation Protein associated with Myc (PAM) is involved in spinal nociceptive processing. Localization and regulation of cyclo-oxygenase-1 and -2 and neuronal nitric oxide synthase in mouse spinal cord The intraspinal release of prostaglandin E2 in a model of acute arthritis is accompanied by an up-regulation of cyclo-oxygenase-2 in the spinal cord The Effect of Spinal and Systemic Administration of Indomethacin on Zymosan-Induced Edema, Mechanical Hyperalgesia, and Thermal Hyperalgesia Opposite effects of rofecoxib on nuclear factor-kappaB and activating protein-1 activation Effects of selective COX-1 and -2 inhibition on formalin-evoked nociceptive behaviour and prostaglandin E(2) release in the spinal cord Celecoxib loses its anti-inflammatory efficacy at high doses through activation of NF-kappaB. Intrarenal expression and distribution of cyclooxygenase isoforms in rats with experimental heart failure Expression of COX-2 by normal and reactive astrocytes in the adult rat central nervous system. Intraplantar zymosan as a reliable, quantifiable model of thermal and mechanical hyperalgesia in the rat Muramyl dipeptide potentiates cytokine-induced activation of inducible nitric oxide synthase in rat astrocytes11Published on the World Wide Web on 2 October 2000
author name string	wds:Q28574729-01F28CFE-BCDB-4540-BE8A-BC7C7EE06399 wds:Q28574729-61C840D0-44A2-476A-BA3B-D3381D146FB5 wds:Q28574729-62E16E69-E510-4FE5-A77A-6E9A894F714F wds:Q28574729-9467F1AC-50F7-4237-BC33-10ED3A714070 wds:Q28574729-A1382EAA-D11F-4E41-A7A0-610C59EF9BAC wds:Q28574729-C96FE08C-68A0-471E-A859-A61C9E0B627A
author name string	Gerd Geisslinger Klaus Scholich Claudiu Marian Annette Hofacker Ovidiu Coste Hong-Van Nguyen
rdfs:label	Downregulation of cytosolic prostaglandin E2 synthase results in decreased nociceptive behavior in rats (en) Downregulation of cytosolic prostaglandin E2 synthase results in decreased nociceptive behavior in rats (nl) Downregulation of cytosolic prostaglandin E2 synthase results in decreased nociceptive behavior in rats (ast)
skos:prefLabel	Downregulation of cytosolic prostaglandin E2 synthase results in decreased nociceptive behavior in rats (en) Downregulation of cytosolic prostaglandin E2 synthase results in decreased nociceptive behavior in rats (nl) Downregulation of cytosolic prostaglandin E2 synthase results in decreased nociceptive behavior in rats (ast)
name	Downregulation of cytosolic prostaglandin E2 synthase results in decreased nociceptive behavior in rats (en) Downregulation of cytosolic prostaglandin E2 synthase results in decreased nociceptive behavior in rats (nl) Downregulation of cytosolic prostaglandin E2 synthase results in decreased nociceptive behavior in rats (ast)

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