About: Cooperation between the Cdk inhibitors p27(KIP1) and p57(KIP2) in the control of tissue growth and development

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About: Cooperation between the Cdk inhibitors p27(KIP1) and p57(KIP2) in the control of tissue growth and development Goto Sponge NotDistinct Permalink

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description	artículu científicu espublizáu en 1998 (ast) vědecký článek publikovaný v roce 1998 (cs) 1998 թվականի հոտեմբերին հրատարակված գիտական հոդված (hy) 1998 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած (hyw) наукова стаття, опублікована в жовтні 1998 (uk) vedecký článok (publikovaný 1998/10/15) (sk) مقالة علمية (نشرت في 15-10-1998) (ar) article scientifique publié en 1998 (fr) wetenschappelijk artikel (gepubliceerd op 1998/10/15) (nl) scientific journal article (en) im Oktober 1998 veröffentlichter wissenschaftlicher Artikel (de)
publication date	wds:Q28512118-B35EF227-EA9F-472E-B542-930570BEB69D
publication date	1998-10-15 00:00:00Z (xsd:dateTime)
cites work	wds:Q28512118-000AD122-E8DF-4FA9-AD41-84F651A50EF2 wds:Q28512118-0333FD91-4454-48FB-BD00-71CC3956007D wds:Q28512118-0CFDC4DE-93F7-401C-99CD-3D1B1DD4CC48 wds:Q28512118-0ECAFEA4-6EDC-40BD-B4C3-458B4ACF26B8 wds:Q28512118-0FDB6CFE-6B43-4D5E-8516-44FF22BD6D02 wds:Q28512118-2B849FEF-D98B-4285-9CF8-1BE53CB2635B wds:Q28512118-34435DEA-CC9D-4904-B5F0-F3D6BFCB42AD wds:Q28512118-448504C4-AF4E-41C3-B442-678E3DE52AAF wds:Q28512118-4E7C7F3D-23AD-475F-9109-C1DC9650248F wds:Q28512118-4EF9D463-1C3A-4639-8713-07B7D2F2BBAB wds:Q28512118-54047A54-C9DA-47A0-8046-8226211F7DF8 wds:Q28512118-5C2F95DF-7998-4793-86CA-BE6CDD61B409 wds:Q28512118-5D4450BF-0A3B-49A6-B0AB-C6619A7A3DD9 wds:Q28512118-602321AB-61CC-47FD-A3A4-E27E0528FF19 wds:Q28512118-690A4106-CAE5-40BB-ABC2-DA5156ADB84F wds:Q28512118-72621B9F-3B64-4E3D-9428-9A151568D569 wds:Q28512118-779437B7-4BF7-4DC5-B14F-1259587E5C5A wds:Q28512118-7E47E8FE-EAEA-49DF-82EC-A3A67E7F21C2 wds:Q28512118-846CD28D-F969-4092-B52B-ECBA73C34EE9 wds:Q28512118-88C94BE1-C179-49B3-98C0-8053364418A1 wds:Q28512118-AF410553-4D71-409E-BF67-A4BCE0BF470A wds:Q28512118-BC149AAF-4826-41E9-A722-53F2B0D4CBBE wds:Q28512118-C2E6E335-B6C4-4453-8EE4-2BDC92A34B15 wds:Q28512118-C34C087D-7DCD-42F4-82C2-B0F77C8921C1 wds:Q28512118-C8A94EAA-F395-4B00-AC2E-21B835EF603F wds:Q28512118-CB7563A8-7034-4259-AF3B-987F7761CDFA wds:Q28512118-D342C369-A2B3-436B-B4A0-06A56C208A51 wds:Q28512118-D5EB5D78-5C71-488E-8437-E0DCD560C79D wds:Q28512118-DB6CCDE1-5559-429E-AD12-FF68346E5124 wds:Q28512118-DF369B36-E6C1-40FE-9E2E-6A6D691330F8 wds:Q28512118-E363E5CB-4F36-475D-A1F5-B7167D18AEB0 wds:Q28512118-E5FC4CFD-C4F8-48F9-BFF8-C5684227E1B0 wds:Q28512118-E6D2EF9B-3EEB-4F8F-AFE9-5A1FA816B800 wds:Q28512118-EE679F2F-0721-4D70-BB31-4994051C12CF wds:Q28512118-FBA0E044-2415-466C-96E9-0ADE614E9D66
cites work	p57KIP2, a structurally distinct member of the p21CIP1 Cdk inhibitor family, is a candidate tumor suppressor gene Differential regulation of E2F transactivation by cyclin/cdk2 complexes Cyclin-mediated inhibition of muscle gene expression via a mechanism that is independent of pRB hyperphosphorylation The retinoblastoma gene family: cousins with overlapping interests. Retinoblastoma protein in growth suppression and death protection Distinct roles for E2F proteins in cell growth control and apoptosis p53-dependent apoptosis produced by Rb-deficiency in the developing mouse lens. Negative regulation of the growth-promoting transcription factor E2F-1 by a stably bound cyclin A-dependent protein kinase Mice lacking p27(Kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors Enhanced growth of mice lacking the cyclin-dependent kinase inhibitor function of p27(Kip1). A syndrome of multiorgan hyperplasia with features of gigantism, tumorigenesis, and female sterility in p27(Kip1)-deficient mice Ablation of the CDK inhibitor p57Kip2 results in increased apoptosis and delayed differentiation during mouse development. Altered cell differentiation and proliferation in mice lacking p57KIP2 indicates a role in Beckwith–Wiedemann syndrome Correlation of terminal cell cycle arrest of skeletal muscle with induction of p21 by MyoD. Mice lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control Role of the INK4a locus in tumor suppression and cell mortality. Ectopic expression of cyclin D1 prevents activation of gene transcription by myogenic basic helix-loop-helix regulators MyoD-induced expression of p21 inhibits cyclin-dependent kinase activity upon myocyte terminal differentiation Induction of the eye lens Deregulated expression of E2F-1 induces S-phase entry and leads to apoptosis Sox1 directly regulates the gamma-crystallin genes and is essential for lens development in mice Retinoblastoma protein positively regulates terminal adipocyte differentiation through direct interaction with C/EBPs p53-independent expression of p21Cip1 in muscle and other terminally differentiating cells Rb binds c-Jun and activates transcription Interaction of myogenic factors and the retinoblastoma protein mediates muscle cell commitment and differentiation Stable binding to E2F is not required for the retinoblastoma protein to activate transcription, promote differentiation, and suppress tumor cell growth E2F1 overexpression in quiescent fibroblasts leads to induction of cellular DNA synthesis and apoptosis. Deregulated transcription factor E2F-1 expression leads to S-phase entry and p53-mediated apoptosis Cdk inhibitors in development and cancer Genetic variation among 129 substrains and its importance for targeted mutagenesis in mice Lens differentiation in vertebrates. A review of cellular and molecular features Regulation of cyclin and cyclin-dependent kinase gene expression during lens differentiation requires the retinoblastoma protein Inhibition of myogenic differentiation in proliferating myoblasts by cyclin D1-dependent kinase Lens complementation system for the genetic analysis of growth, differentiation, and apoptosis in vivo Rb functions to inhibit apoptosis during myocyte differentiation
author name string	wds:Q28512118-13E57C53-B7D9-4909-9B56-80F5642DD5AB wds:Q28512118-15B60593-D5C4-4B83-8C74-3A1418053F40 wds:Q28512118-2069A67B-61AB-4DA3-8420-6B9547CEAE1D wds:Q28512118-378E0095-E6E2-4396-8618-BB2FDEA6A7F1 wds:Q28512118-473A364E-392D-420A-B93C-BC4573469B72
author name string	P. Zhang J. W. Harper S. J. Elledge C. Wong R. A. DePinho
rdfs:label	Cooperation between the Cdk inhibitors p27(KIP1) and p57(KIP2) in the control of tissue growth and development (en) Cooperation between the Cdk inhibitors p27(KIP1) and p57(KIP2) in the control of tissue growth and development (nl) Cooperation between the Cdk inhibitors p27(KIP1) and p57(KIP2) in the control of tissue growth and development (ast)
skos:prefLabel	Cooperation between the Cdk inhibitors p27(KIP1) and p57(KIP2) in the control of tissue growth and development (en) Cooperation between the Cdk inhibitors p27(KIP1) and p57(KIP2) in the control of tissue growth and development (nl) Cooperation between the Cdk inhibitors p27(KIP1) and p57(KIP2) in the control of tissue growth and development (ast)

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