About: Acute mutation of retinoblastoma gene function is sufficient for cell cycle re-entry

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scientific journal article

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description	artículu científicu espublizáu en 2003 (ast) vědecký článek publikovaný v roce 2003 (cs) наукова стаття, опублікована в липні 2003 (uk) 2003 թվականի հուլիսին հրատարակված գիտական հոդված (hy) 2003 թուականի Յուլիսին հրատարակուած գիտական յօդուած (hyw) article publié dans la revue scientifique Nature (fr) wetenschappelijk artikel (gepubliceerd op 2003/07/10) (nl) vedecký článok (publikovaný 2003/07/10) (sk) مقالة علمية (نشرت في 10-7-2003) (ar) im Juli 2003 veröffentlichter wissenschaftlicher Artikel (de) scientific journal article (en)
publication date	wds:Q28509466-5A176AF3-9686-4620-9925-6A7AC54F4FBD
publication date	2003-07-10 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q28509466-6A874B7C-11CA-4DD4-B0F0-4D1DD24D4DAF
language of work or name	English
cites work	wds:Q28509466-22521737-06FB-41CE-8134-785173687F1E wds:Q28509466-366F2E5E-516F-4571-91D8-3F4C8D0CC619 wds:Q28509466-49DCF5A7-8F22-41CE-AD31-16F1D9146042 wds:Q28509466-4DF857D2-0BBE-4CB1-B858-721FBB71145D wds:Q28509466-649ABB7E-F7B5-451F-987E-BCFC219A999F wds:Q28509466-6A93C11E-D72C-4B0F-A317-96755BF2D3E5 wds:Q28509466-78AF2859-BD54-4544-9E32-82557AE15417 wds:Q28509466-82EB2AAC-7248-4FB7-A2C6-28C0319D3707 wds:Q28509466-8BC6F962-91B8-4F45-9B60-4C2A91A79714 wds:Q28509466-8D7B1D07-5B0F-491C-9317-CA2BC1E69966 wds:Q28509466-9AFEA2D0-DA66-45FB-92E5-CA2E5DA42AD9 wds:Q28509466-A58111FD-8E84-47C9-ACD3-17E0CAEA20E3 wds:Q28509466-AE13F429-7EE4-4D4F-9E74-4636FB387D4D wds:Q28509466-BA7256CA-9227-4D2D-BCCF-08A8424AD200 wds:Q28509466-BE6A6D6B-4BDA-47DD-9EFC-F3529887A910 wds:Q28509466-C5E51BBC-9462-43FB-8380-06517200E3E2 wds:Q28509466-D84EAA69-E9FF-4EAD-82AD-2205C654661D wds:Q28509466-EDFFC2C5-5AAC-446A-9726-FB0632021D90 wds:Q28509466-EEC9A100-EE21-48E1-9E86-69CC5D70D540 wds:Q28509466-EF60BE70-5915-4814-8196-523CCD8852F5 wds:Q28509466-F823A322-629F-45C6-8E84-C9595DD213E3 wds:Q28509466-F8ABA819-4D07-4ED7-A16F-8326CD334273
cites work	The Hallmarks of Cancer A senescence program controlled by p53 and p16INK4a contributes to the outcome of cancer therapy Reinitiation of DNA synthesis and cell division in senescent human fibroblasts by microinjection of anti-p53 antibodies pRB and p107/p130 are required for the regulated expression of different sets of E2F responsive genes. The retinoblastoma tumour suppressor in development and cancer Targeted disruption of the three Rb-related genes leads to loss of G(1) control and immortalization Ablation of the retinoblastoma gene family deregulates G(1) control causing immortalization and increased cell turnover under growth-restricting conditions Sibling rivalry in the E2F family A system for stable expression of short interfering RNAs in mammalian cells Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a Quantitative studies of the growth of mouse embryo cells in culture and their development into established lines Flp-mediated tissue-specific inactivation of the retinoblastoma tumor suppressor gene in the mouse Cancer modeling in the modern era: progress and challenges Cell lines established by a temperature-sensitive simian virus 40 large-T-antigen gene are growth restricted at the nonpermissive temperature Reversal of senescence in mouse fibroblasts through lentiviral suppression of p53. Conditional mouse models of sporadic cancer The serial cultivation of human diploid cell strains A lentivirus-based system to functionally silence genes in primary mammalian cells, stem cells and transgenic mice by RNA interference Suppression of the p53- or pRB-mediated G1 checkpoint is required for E2F-induced S-phase entry Delivery of the Cre recombinase by a self-deleting lentiviral vector: efficient gene targeting in vivo Conditional mutation of Rb causes cell cycle defects without apoptosis in the central nervous system p27 deficiency desensitizes Rb-/- cells to signals that trigger apoptosis during pituitary tumor development
author name string	wds:Q28509466-002D3BB0-3E01-4A4A-A5CC-D7CFEDE25248 wds:Q28509466-9A392D28-D1C8-4F96-B951-114ED3CAC196 wds:Q28509466-D25B28DC-FA9C-49ED-8CDF-F2F2FCDF5728
OpenCitations bibliographic resource ID	wds:Q28509466-25D63CFB-3B60-4232-BD85-BED1AD21C59E
OpenCitations bibliographic resource ID	https://w3id.org/oc/corpus/br/4425970
author name string	Pedro A. Pérez-Mancera Abigail L. Miller Julianne M. Wysocki
OpenCitations bibliographic resource ID	4425970
rdfs:label	Acute mutation of retinoblastoma gene function is sufficient for cell cycle re-entry (en) Acute mutation of retinoblastoma gene function is sufficient for cell cycle re-entry (nl) Acute mutation of retinoblastoma gene function is sufficient for cell cycle re-entry (ast)
skos:prefLabel	Acute mutation of retinoblastoma gene function is sufficient for cell cycle re-entry (en) Acute mutation of retinoblastoma gene function is sufficient for cell cycle re-entry (nl) Acute mutation of retinoblastoma gene function is sufficient for cell cycle re-entry (ast)
name	Acute mutation of retinoblastoma gene function is sufficient for cell cycle re-entry (en) Acute mutation of retinoblastoma gene function is sufficient for cell cycle re-entry (nl) Acute mutation of retinoblastoma gene function is sufficient for cell cycle re-entry (ast)
author	wds:Q28509466-29D347F6-5671-4FCE-8ECF-A79E7AF739EB wds:Q28509466-986D6B1A-57A5-41BC-863A-1B08A535F7BF
author	Tyler Jacks Julien Sage
title	wds:Q28509466-C1F0ACA7-ED6E-479A-BB4F-6C66CD08EE91
title	Acute mutation of retinoblastoma gene function is sufficient for cell cycle re-entry (en)
page(s)	wds:Q28509466-654DADF4-C1F3-4D85-82E9-1059A1C2CB3B
page(s)	223–228
instance of	wds:Q28509466-37BB3979-AC4D-41EE-B2E5-57EF28C4DCEA
instance of	scholarly article
main subject	wds:Q28509466-1E6EC526-8C72-4FE6-88F4-78DB88D0AED2 wds:Q28509466-2EEEA39D-854F-40AC-BFFE-AF09E6569D79 wds:Q28509466-AFDC5E8F-F7FC-4B25-BF12-D0AAE4E8F48A
main subject	retinoblastoma RB transcriptional corepressor 1 RB transcriptional corepressor like 1
PubMed ID	wds:Q28509466-4375A276-CBCF-478A-A70D-E8AADE38EDC8
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/12853964
PubMed ID	12853964
published in	wds:Q28509466-69F36F8E-2E64-4CA9-A75B-A93D99A57F0A
published in	Nature
issue	wds:Q28509466-54C9EB5C-EA3E-46E9-994C-37F35CC2E39E

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