About: Nf1 deficiency causes Ras-mediated granulocyte/macrophage colony stimulating factor hypersensitivity and chronic myeloid leukaemia

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Nf1 deficiency causes Ras-mediated granulocyte/macrophage colony stimulating factor hypersensitivity and chronic myeloid leukaemia Goto Sponge NotDistinct Permalink

An Entity of Type : wikibase:Item, within Data Space : wikidata.demo.openlinksw.com associated with source document(s)

scientific journal article

Attributes	Values
rdf:type	Item
description	articolo scientifico (it) artículu científicu espublizáu en 1996 (ast) vědecký článek publikovaný v roce 1996 (cs) 1996 թուականի Փետրուարին հրատարակուած գիտական յօդուած (hyw) مقالة علمية (نشرت في فبراير 1996) (ar) 1996 թվականի փետրվարին հրատարակված գիտական հոդված (hy) vedecký článok (publikovaný 1996/02/01) (sk) научни чланак (објављен 1996/02/01) (sr) наукова стаття, опублікована в лютому 1996 (uk) wetenschappelijk artikel (gepubliceerd op 1996/02/01) (nl) scientific journal article (en) im Februar 1996 veröffentlichter wissenschaftlicher Artikel (de)
publication date	wds:Q28505914-3C46CF16-584A-4A8C-9580-AE91935FC0E2
publication date	1996-02-01 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q28505914-90C83017-25D2-48BF-928F-1A7A326B9357
language of work or name	English
exact match	wds:Q28505914-84F554FF-1470-46E1-A9C5-9CEC47957AF5
exact match	https://scigraph.springernature.com/pub.10.1038/ng0296-137
cites work	wds:Q28505914-000FA1DC-B1C8-4571-9962-F603E92C85B4 wds:Q28505914-08A90063-B0B4-4996-B17F-E83C50D43C29 wds:Q28505914-1117B246-8AFF-4B40-B818-05D489252B86 wds:Q28505914-2214980C-EA96-4A36-AFC5-1C61D6C2D7ED wds:Q28505914-23131328-4FF2-4578-90EE-7808D7061D43 wds:Q28505914-24CB3B3E-6AB7-4C68-A3D4-84C121CC3C0D wds:Q28505914-2CDA81AF-E98B-4317-A21B-0345DBEF3886 wds:Q28505914-2FCB927C-A07A-42F2-A4E8-470D44EFB949 wds:Q28505914-55B4A580-D70D-4F9B-8C15-B993008D197D wds:Q28505914-5EBD03FE-8853-4AC1-8EAF-8B7E3B9D7237 wds:Q28505914-77289C5B-51B3-4394-BBD1-DCBD9C783A7A wds:Q28505914-7E96F786-16CB-4213-B662-5E03C5C153DE wds:Q28505914-8D8131F2-54F6-48F5-8E20-EC8AF266D331 wds:Q28505914-9CBCAD67-D4E4-4D4E-83DE-925A9453F79A wds:Q28505914-B227A3F1-E50D-4FD7-B239-8220217C368D wds:Q28505914-BD3A4C0F-C057-473E-B291-A38EDEB00E1F wds:Q28505914-CD56AEF7-29AE-4D7E-8F29-A267C2520DF7 wds:Q28505914-D33962C9-BE5D-4FF9-B1AB-B766052CA8F3 wds:Q28505914-D46A5B95-69AE-4C16-8A75-25E793CFB2E0 wds:Q28505914-D717DE5B-8119-4508-AF93-05B231315299 wds:Q28505914-DE0F3FF3-38EB-4E87-B737-C9D4326A06FF wds:Q28505914-F9F96E0B-6830-4F37-814D-18E47655EC08
cites work	Bcr-Abl oncoproteins bind directly to activators of the Ras signalling pathway Involvement of ras p21 protein in signal-transduction pathways from interleukin 2, interleukin 3, and granulocyte/macrophage colony-stimulating factor, but not from interleukin 4 ras oncogenes: their role in neoplasia BCR-ABL-induced oncogenesis is mediated by direct interaction with the SH2 domain of the GRB-2 adaptor protein Aberrant regulation of ras proteins in malignant tumour cells from type 1 neurofibromatosis patients Targeted disruption of the neurofibromatosis type-1 gene leads to developmental abnormalities in heart and various neural crest-derived tissues Tumour predisposition in mice heterozygous for a targeted mutation in Nf1 Abnormal regulation of mammalian p21ras contributes to malignant tumor growth in von Recklinghausen (type 1) neurofibromatosis Transgenic mice expressing a hemopoietic growth factor gene (GM-CSF) develop accumulations of macrophages, blindness, and a fatal syndrome of tissue damage Neurofibromatosis and childhood leukemia Tumorigenesis by slow-transforming retroviruses--an update Evi-2, a common integration site involved in murine myeloid leukemogenesis Neurofibromatosis and cancer. Neurofibromin can inhibit Ras-dependent growth by a mechanism independent of its GTPase-accelerating function The neurofibromatosis type 1 gene and its protein product, neurofibromin. RAS gene mutations in acute and chronic myelocytic leukemias, chronic myeloproliferative disorders, and myelodysplastic syndromes Loss of the normal NF1 allele from the bone marrow of children with type 1 neurofibromatosis and malignant myeloid disorders Subacute and chronic myelomonocytic leukemia in children (juvenile CML). Clinical and hematologic observations, and identification of prognostic factors Neurofibromatosis type 1 gene mutations in neuroblastoma Inactivation of the NF1 gene in human melanoma and neuroblastoma cell lines without impaired regulation of GTP.Ras Retroviral integration at the Evi-2 locus in BXH-2 myeloid leukemia cell lines disrupts Nf1 expression without changes in steady-state Ras-GTP levels. Density distribution analysis ofIn vivo andIn vitro colony forming cells in developing fetal liver
author name string	wds:Q28505914-138E4741-BCD7-4DB9-BA4B-41BBF8A798FB wds:Q28505914-34725578-42CB-4368-8D07-9CB08776AABB wds:Q28505914-5600F994-AA47-4941-B2CD-7B49C8F33EC6 wds:Q28505914-AC770477-3E34-4D83-9B6C-BEAF23FFD936
author name string	N. A. Jenkins N. G. Copeland C. I. Brannan D. A. Largaespada
rdfs:label	Nf1 deficiency causes Ras-mediated granulocyte/macrophage colony stimulating factor hypersensitivity and chronic myeloid leukaemia (en) Nf1 deficiency causes Ras-mediated granulocyte/macrophage colony stimulating factor hypersensitivity and chronic myeloid leukaemia (nl) Nf1 deficiency causes Ras-mediated granulocyte/macrophage colony stimulating factor hypersensitivity and chronic myeloid leukaemia (ast)
skos:prefLabel	Nf1 deficiency causes Ras-mediated granulocyte/macrophage colony stimulating factor hypersensitivity and chronic myeloid leukaemia (en) Nf1 deficiency causes Ras-mediated granulocyte/macrophage colony stimulating factor hypersensitivity and chronic myeloid leukaemia (nl) Nf1 deficiency causes Ras-mediated granulocyte/macrophage colony stimulating factor hypersensitivity and chronic myeloid leukaemia (ast)
name	Nf1 deficiency causes Ras-mediated granulocyte/macrophage colony stimulating factor hypersensitivity and chronic myeloid leukaemia (en) Nf1 deficiency causes Ras-mediated granulocyte/macrophage colony stimulating factor hypersensitivity and chronic myeloid leukaemia (nl) Nf1 deficiency causes Ras-mediated granulocyte/macrophage colony stimulating factor hypersensitivity and chronic myeloid leukaemia (ast)
title	wds:Q28505914-760E6D25-7412-48E8-94A1-D8B1BE31D363
title	Nf1 deficiency causes Ras-mediated granulocyte/macrophage colony stimulating factor hypersensitivity and chronic myeloid leukaemia (en)
page(s)	wds:Q28505914-91BBC45F-A8F8-4778-ACBB-2CFB4D1EC4EE
page(s)	137–143
instance of	wds:Q28505914-0B372BC3-B4F7-4B0A-A46C-1DBDAB3C30AA
instance of	scholarly article
main subject	wds:Q28505914-1D68A4B1-350C-40A6-B608-6AFD00B02FBC wds:Q28505914-42B46D91-A02A-4CD1-9EA7-08D0567A60C7 wds:Q28505914-BC50A217-8B21-4442-A531-ADA57F08CA21
main subject	leukemia macrophage Neurofibromin 1
PubMed ID	wds:Q28505914-C8CA0787-9B36-4C58-9C65-9C5A215377C4
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/8563750
PubMed ID	8563750
published in	wds:Q28505914-2FE88B0F-2288-4D3F-B9F5-C9965C9F3521
published in	Nature Genetics
issue	wds:Q28505914-45DFE5A4-3BA6-48A0-BAA4-E2EAAE46A6AB
volume	wds:Q28505914-1624A2C0-FE09-4161-8256-269430A51ECF
issue	2

Faceted Search & Find service v1.16.117 as of May 05 2024

Alternative Linked Data Documents: ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3239 as of May 5 2024, on Linux (x86_64-centos_6-linux-gnu), Single-Server Edition (378 GB total memory, 180 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2025 OpenLink Software