About: THM1 negatively modulates mouse sonic hedgehog signal transduction and affects retrograde intraflagellar transport in cilia

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About: THM1 negatively modulates mouse sonic hedgehog signal transduction and affects retrograde intraflagellar transport in cilia Goto Sponge NotDistinct Permalink

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description	articolo scientifico (it) article scientifique publié en 2008 (fr) artículu científicu espublizáu en 2008 (ast) vědecký článek publikovaný v roce 2008 (cs) 2008 թվականի ապրիլին հրատարակված գիտական հոդված (hy) 2008 թուականի Ապրիլին հրատարակուած գիտական յօդուած (hyw) наукова стаття, опублікована у квітні 2008 (uk) vedecký článok (publikovaný 2008/04/01) (sk) مقالة علمية (نشرت في أبريل 2008) (ar) wetenschappelijk artikel (gepubliceerd op 2008/04/01) (nl) im April 2008 veröffentlichter wissenschaftlicher Artikel (de) scientific journal article (en)
publication date	wds:Q28505803-8D8B34B7-B231-494D-9343-74B25B705556
publication date	2008-04-01 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q28505803-5141B048-45E3-4FD8-9527-28205505540E
language of work or name	English
cites work	wds:Q28505803-06C943A2-D3D6-4A36-8B49-0461B62046FE wds:Q28505803-0A072B5C-5EB4-41A7-A680-F5A3E0CB3E9D wds:Q28505803-12873591-B7E6-4096-A242-A98C602A6118 wds:Q28505803-12A617CA-A6DB-4302-BF08-1E2D85176CDE wds:Q28505803-175CEA67-5562-47B9-8AB9-0F7C53902919 wds:Q28505803-179A2C80-0DF2-48C6-AC0B-91AEFC2BF05D wds:Q28505803-243AB489-9B92-41DE-9F6E-E63025B60AAE wds:Q28505803-283E1008-9EC9-4DD5-804A-335EE2F092F5 wds:Q28505803-2B894D83-7A22-4748-B19C-DBC42647624B wds:Q28505803-2BFFA5DB-8EDF-4424-B270-BF6B8C838528 wds:Q28505803-35E633D8-DB3A-4F66-B121-FDA6A957FE0F wds:Q28505803-36B988EA-ACF9-4057-95BB-BB1961162058 wds:Q28505803-3CF1EED3-457C-49DF-9461-353001A2BC1A wds:Q28505803-42F4F61C-38AC-4685-AF99-0D7A29D758B9 wds:Q28505803-47DAE5F5-59CC-457A-8B9D-7E580B3AE852 wds:Q28505803-4B8425C4-786A-495A-A872-718E2D7101D9 wds:Q28505803-4BCF5534-CC96-4696-8D17-DCDCBF06B633 wds:Q28505803-696EE415-F344-40DB-8936-769BA8BC830D wds:Q28505803-6DA38A00-2F44-41E9-AF95-8424CDAB3277 wds:Q28505803-6E2AA6E5-8AD8-46F8-82ED-0192CE0E4395 wds:Q28505803-76A61522-A969-4472-AA9E-63549B6E7968 wds:Q28505803-7FA133A3-DA8D-4AF6-A088-54F339B878E8 wds:Q28505803-89E99592-1D4E-46A7-8CAA-24B7D882C8EF wds:Q28505803-8BCBAFC8-A4AE-43A7-9DE9-90AAA663BF07 wds:Q28505803-8C74D88D-DAE1-4E8C-8301-DE523A0B0193 wds:Q28505803-908AE5FD-F55A-40EF-B4BB-F5BE87823BA8 wds:Q28505803-98006F3E-F6B9-43D3-A46F-AFAB42D5710E wds:Q28505803-9DEA7443-FB4A-470C-8BB7-18A8380C3DD3 wds:Q28505803-A149C8FD-5912-4E22-8810-A6A8F75AE940 wds:Q28505803-A3C2EDA7-5F4A-42C1-A0C1-CDDFBC58C77E wds:Q28505803-A6EC3ED7-A0EA-47E2-BA7C-BBF13636A1EC wds:Q28505803-B289D6AC-3941-442C-AB95-4F28199A0422 wds:Q28505803-B8822968-77CB-44B9-8B42-919EA4487482 wds:Q28505803-BB4E9D25-51A7-48F2-A1DB-2FB3E20F16F3 wds:Q28505803-C437E721-823F-48F1-AECB-AF13B5141469 wds:Q28505803-C6CAAE5F-581B-4B10-9262-03BF638D8CF5 wds:Q28505803-C9BC1F02-8471-42FE-963A-F7F1F7CDA614 wds:Q28505803-CD6087ED-B5E4-451E-BE17-D6C5C20D9978 wds:Q28505803-CF7B8FD3-D8C6-4C9C-A538-92CBAF173CD4 wds:Q28505803-DC5696DC-72DA-447C-982E-D6318B98B979 wds:Q28505803-DD8581D7-318B-472A-8C11-497AAE13525E wds:Q28505803-E516CD68-6558-4A73-B2DE-B691D41A63F5 wds:Q28505803-E75644AE-7D72-4F31-9246-537BADDACD5C wds:Q28505803-F0B468E7-5D1D-4E46-A73D-8DA5087B0DE1 wds:Q28505803-F1C07FE2-5B96-4702-BC43-D478B328F6A3
cites work	The sonic hedgehog-patched-gli pathway in human development and disease The Bardet-Biedl protein BBS4 targets cargo to the pericentriolar region and is required for microtubule anchoring and cell cycle progression Patched1 regulates hedgehog signaling at the primary cilium Altered neural cell fates and medulloblastoma in mouse patched mutants Hedgehog signaling in animal development: paradigms and principles Hippi is essential for node cilia assembly and Sonic hedgehog signaling Rab23 is an essential negative regulator of the mouse Sonic hedgehog signalling pathway Hedgehog-regulated processing of Gli3 produces an anterior/posterior repressor gradient in the developing vertebrate limb Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function Advanced mammalian gene transfer: high titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line A dynein light chain is essential for the retrograde particle movement of intraflagellar transport (IFT) Basal body dysfunction is a likely cause of pleiotropic Bardet-Biedl syndrome A novel dynein light intermediate chain colocalizes with the retrograde motor for intraflagellar transport at sites of axoneme assembly in chlamydomonas and Mammalian cells The intraflagellar transport protein IFT20 is associated with the Golgi complex and is required for cilia assembly Ftm is a novel basal body protein of cilia involved in Shh signalling The Shh-independent activator function of the full-length Gli3 protein and its role in vertebrate limb digit patterning Manifestation of the limb prepattern: limb development in the absence of sonic hedgehog function Utilization of a whole genome SNP panel for efficient genetic mapping in the mouse Intraflagellar transport and the flagellar tip complex Loss of the retrograde motor for IFT disrupts localization of Smo to cilia and prevents the expression of both activator and repressor functions of Gli Cilia and Hedgehog responsiveness in the mouse Hedgehog signalling in the mouse requires intraflagellar transport proteins Gli2 and Gli3 localize to cilia and require the intraflagellar transport protein polaris for processing and function Mouse intraflagellar transport proteins regulate both the activator and repressor functions of Gli transcription factors Efficient generation and mapping of recessive developmental mutations using ENU mutagenesis Biochemical evidence that patched is the Hedgehog receptor Shh and Gli3 are dispensable for limb skeleton formation but regulate digit number and identity Mutant sensory cilia in the nematode Caenorhabditis elegans Smoothened regulates activator and repressor functions of Hedgehog signaling via two distinct mechanisms Vertebrate Smoothened functions at the primary cilium The graded response to Sonic Hedgehog depends on cilia architecture Identification of a novel family of oligodendrocyte lineage-specific basic helix-loop-helix transcription factors Specific and redundant functions of Gli2 and Gli3 zinc finger genes in skeletal patterning and development Diminished Sonic hedgehog signaling and lack of floor plate differentiation in Gli2 mutant mice Neuronal specification in the spinal cord: inductive signals and transcriptional codes Protein particles in Chlamydomonas flagella undergo a transport cycle consisting of four phases Distinct mutants of retrograde intraflagellar transport (IFT) share similar morphological and molecular defects XBX-1 encodes a dynein light intermediate chain required for retrograde intraflagellar transport and cilia assembly in Caenorhabditis elegans

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