About: Multiallelic disruption of the rictor gene in mice reveals that mTOR complex 2 is essential for fetal growth and viability

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About: Multiallelic disruption of the rictor gene in mice reveals that mTOR complex 2 is essential for fetal growth and viability Goto Sponge NotDistinct Permalink

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scientific journal article

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rdf:type	Item
description	artículu científicu espublizáu en 2006 (ast) vědecký článek publikovaný v roce 2006 (cs) 2006 թվականի հոտեմբերին հրատարակված գիտական հոդված (hy) 2006 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած (hyw) наукова стаття, опублікована в жовтні 2006 (uk) مقالة علمية (نشرت في أكتوبر 2006) (ar) vedecký článok (publikovaný 2006/10/01) (sk) wetenschappelijk artikel (gepubliceerd op 2006/10/01) (nl) im Oktober 2006 veröffentlichter wissenschaftlicher Artikel (de) scientific journal article (en)
publication date	wds:Q28504594-4D1A7DF7-3E2D-4600-B427-F352293C41F7
publication date	2006-10-01 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q28504594-A8C28CE1-EFC6-4818-AE05-DE20F9D7CE30
language of work or name	English
author name string	wds:Q28504594-1D5AF829-54D5-4FFC-886B-CE329118ADC0 wds:Q28504594-40DF9DC1-D11A-450E-979B-08B743984402 wds:Q28504594-C3682F81-FC5B-45F8-B895-750D5ED8658A
OpenCitations bibliographic resource ID	wds:Q28504594-1A3F12F8-5445-4206-BC30-B049A12E0298
OpenCitations bibliographic resource ID	https://w3id.org/oc/corpus/br/916235
author name string	Chiyo Shiota Jeong-Taek Woo Kathy D. Shelton
OpenCitations bibliographic resource ID	916235
rdfs:label	Multiallelic disruption of the rictor gene in mice reveals that mTOR complex 2 is essential for fetal growth and viability (en) Multiallelic disruption of the rictor gene in mice reveals that mTOR complex 2 is essential for fetal growth and viability (nl) Multiallelic disruption of the rictor gene in mice reveals that mTOR complex 2 is essential for fetal growth and viability (ast)
skos:prefLabel	Multiallelic disruption of the rictor gene in mice reveals that mTOR complex 2 is essential for fetal growth and viability (en) Multiallelic disruption of the rictor gene in mice reveals that mTOR complex 2 is essential for fetal growth and viability (nl) Multiallelic disruption of the rictor gene in mice reveals that mTOR complex 2 is essential for fetal growth and viability (ast)
name	Multiallelic disruption of the rictor gene in mice reveals that mTOR complex 2 is essential for fetal growth and viability (en) Multiallelic disruption of the rictor gene in mice reveals that mTOR complex 2 is essential for fetal growth and viability (nl) Multiallelic disruption of the rictor gene in mice reveals that mTOR complex 2 is essential for fetal growth and viability (ast)
author	wds:Q28504594-A8B2CC21-E4EF-45C0-BA94-EA299EF45A04 wds:Q28504594-E7D56E4F-3736-4770-9FE5-792072E20102
author	Mark Magnuson Jill Lindner
title	wds:Q28504594-C1898BCC-163C-4689-91C9-9AF60FB3E8E9
title	Multiallelic disruption of the rictor gene in mice reveals that mTOR complex 2 is essential for fetal growth and viability (en)
page(s)	wds:Q28504594-296B6867-AE80-4E63-94DD-5514D4463BC1
page(s)	583–589
instance of	wds:Q28504594-BCD2CA8F-0401-4095-97A1-8D746EA2A88C
instance of	scholarly article
main subject	wds:Q28504594-8464BE7C-E69D-4CC7-9877-CEFB3747F523
main subject	RPTOR independent companion of MTOR, complex 2
PubMed ID	wds:Q28504594-429E7766-9A59-42F8-968C-FDA4B2FCEF46
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/16962829
PubMed ID	16962829
published in	wds:Q28504594-1546A3EC-4331-4C11-8CA5-8E935CC5A460
published in	Developmental Cell
issue	wds:Q28504594-BDCE1939-EB04-40D8-9724-9F36465C5AC8
volume	wds:Q28504594-C3D01D98-E197-413D-8786-05D3DBC9729F
issue	4
volume	11
DOI	wds:Q28504594-78E44F17-B70D-47E4-8FD3-FFDF21B2A35F
DOI	http://dx.doi.org/10.1016/J.DEVCEL.2006.08.013
DOI	10.1016/J.DEVCEL.2006.08.013
ResearchGate publication ID	wds:Q28504594-C828E6FA-FCDB-4160-9C1D-765753A49E0A
ResearchGate publication ID	6827439
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q28504594
is cites work of	Myeloid-specific Rictor deletion induces M1 macrophage polarization and potentiates in vivo pro-inflammatory response to lipopolysaccharide Targeting mTOR: prospects for mTOR complex 2 inhibitors in cancer therapy mTOR complex 2 is required for the development of prostate cancer induced by Pten loss in mice Vital roles of mTOR complex 2 in Notch-driven thymocyte differentiation and leukemia mTOR activates the VPS34-UVRAG complex to regulate autolysosomal tubulation and cell survival mTOR-dependent cell survival mechanisms mTOR signaling in growth control and disease Evidence for direct activation of mTORC2 kinase activity by phosphatidylinositol 3,4,5-trisphosphate PI3K regulation of the SKP-2/p27 axis through mTORC2. Rapamycin and mTOR kinase inhibitors mTORC2 is required for proliferation and survival of TSC2-null cells mTOR kinase inhibitors promote antibody class switching via mTORC2 inhibition. Rictor/mTORC2 pathway in oocytes regulates folliculogenesis, and its inactivation causes premature ovarian failure Essential function of TORC2 in PKC and Akt turn motif phosphorylation, maturation and signalling mTORC2 regulates neutrophil chemotaxis in a cAMP- and RhoA-dependent fashion mTORC1 signaling: what we still don't know PI3K/mTOR signaling regulates prostatic branching morphogenesis Akt is efficiently activated by PIF-pocket- and PtdIns(3,4,5)P3-dependent mechanisms leading to resistance to PDK1 inhibitors TSC1 controls macrophage polarization to prevent inflammatory disease. BSTA promotes mTORC2-mediated phosphorylation of Akt1 to suppress expression of FoxC2 and stimulate adipocyte differentiation The mammalian target of rapamycin complex 2 controls folding and stability of Akt and protein kinase C mTOR complex 2 (mTORC2) controls hydrophobic motif phosphorylation and activation of serum- and glucocorticoid-induced protein kinase 1 (SGK1) Polycystin-1 induces cell migration by regulating phosphatidylinositol 3-kinase-dependent cytoskeletal rearrangements and GSK3beta-dependent cell cell mechanical adhesion c-Src regulates Akt signaling in response to ghrelin via beta-arrestin signaling-independent and -dependent mechanisms Active-site inhibitors of mTOR target rapamycin-resistant outputs of mTORC1 and mTORC2 Mammalian target of rapamycin protein complex 2 regulates differentiation of Th1 and Th2 cell subsets via distinct signaling pathways mTOR complex 2 signaling and functions Rictor/TORC2 regulates Caenorhabditis elegans fat storage, body size, and development through sgk-1 Rictor/TORC2 regulates fat metabolism, feeding, growth, and life span in Caenorhabditis elegans Mechanistic or mammalian target of rapamycin (mTOR) may determine robustness in young male mice at the cost of accelerated aging Fat cell-specific ablation of rictor in mice impairs insulin-regulated fat cell and whole-body glucose and lipid metabolism Dysregulation of the norepinephrine transporter sustains cortical hypodopaminergia and schizophrenia-like behaviors in neuronal rictor null mice mTOR signaling in tumorigenesis Muscle-specific deletion of rictor impairs insulin-stimulated glucose transport and enhances Basal glycogen synthase activity Deletion of Rictor in neural progenitor cells reveals contributions of mTORC2 signaling to tuberous sclerosis complex mTOR and cancer: many loops in one pathway. mTOR signaling: at the crossroads of plasticity, memory and disease Identification of Akt-independent regulation of hepatic lipogenesis by mammalian target of rapamycin (mTOR) complex 2 A dynamic network model of mTOR signaling reveals TSC-independent mTORC2 regulation Ku-0063794 is a specific inhibitor of the mammalian target of rapamycin (mTOR)

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