About: Loss of Cul1 results in early embryonic lethality and dysregulation of cyclin E

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scientific journal article

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rdf:type	Item
description	articolo scientifico (it) artículu científicu espublizáu en 1999 (ast) vědecký článek publikovaný v roce 1999 (cs) 1999 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած (hyw) наукова стаття, опублікована в жовтні 1999 (uk) vedecký článok (publikovaný 1999/10/01) (sk) 1999 թվականի հոտեմբերին հրատարակված գիտական հոդված (hy) مقالة علمية (نشرت في أكتوبر 1999) (ar) научни чланак (објављен 1999/10/01) (sr) article scientifique publié en 1999 (fr) wetenschappelijk artikel (gepubliceerd op 1999/10/01) (nl) scientific journal article (en) im Oktober 1999 veröffentlichter wissenschaftlicher Artikel (de)
publication date	wds:Q28504517-AC77781A-7A45-46D7-B360-F3A8C5FC55D9
publication date	1999-10-01 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q28504517-D6DE7E93-5BE4-431B-952B-D1ECFB5BA5AF
language of work or name	English
cites work	wds:Q28504517-0BF2E687-3F33-4544-8F03-2179F65B9166 wds:Q28504517-0C734885-FC7F-4083-8F58-A650DC381BC0 wds:Q28504517-27B77E97-B028-4F4A-AF7C-6A81DE946655 wds:Q28504517-31C3591B-76CF-44C4-AC1B-5DF0AF3421E7 wds:Q28504517-3CB5FCFD-D7EA-41D7-9251-97A36DFA2166 wds:Q28504517-505B505C-23EA-471D-AE87-0B21E51B9A3E wds:Q28504517-56429B90-27B4-4514-8B40-ABECA0DD7196 wds:Q28504517-5B35BB98-A5A0-4548-97D1-506A0A8FDD11 wds:Q28504517-5BB55EDC-5E0C-46AA-9D84-FE8A6A7294B5 wds:Q28504517-5FF93905-2884-4004-B4BD-037F5F408C9E wds:Q28504517-87D2E264-9B82-4F03-BD33-4961A8A0F810 wds:Q28504517-8F7DCF9B-6F1B-4E0E-81BE-B628E3665060 wds:Q28504517-911C5258-C0A2-4734-B4B5-D6BF8F244DF3 wds:Q28504517-914A2422-8624-4DCD-95DA-3194FC33EB64 wds:Q28504517-A5EFF731-5C17-4BDD-8902-A624B8110AD9 wds:Q28504517-BABCDBC3-94E2-4848-854D-8DEB34E522C2 wds:Q28504517-C7C5CF89-CB69-44FB-AC3C-4B0D9792AA38 wds:Q28504517-C8816906-285C-4197-8416-515D7EF5D5E6 wds:Q28504517-E87B3565-ACCB-4E8B-AFB1-74CF8F413BD2 wds:Q28504517-EE875D51-B99D-48D7-BC88-8D14CA39E8D6 wds:Q28504517-F208CBE2-90E8-4E86-866E-124F22D9745F wds:Q28504517-F272C44E-6FCD-4D9A-9418-98CBA0F908E8 wds:Q28504517-F46C3329-E4CB-4C0A-BCD4-089DCCD6BFCE
cites work	Acceleration of the G1/S phase transition by expression of cyclins D1 and E with an inducible system Overexpression of mouse D-type cyclins accelerates G1 phase in rodent fibroblasts Mdm2 association with p53 targets its ubiquitination Human CUL1 forms an evolutionarily conserved ubiquitin ligase complex (SCF) with SKP1 and an F-box protein IkappaBalpha ubiquitination is catalyzed by an SCF-like complex containing Skp1, cullin-1, and two F-box/WD40-repeat proteins, betaTrCP1 and betaTrCP2. Human CUL-1 associates with the SKP1/SKP2 complex and regulates p21(CIP1/WAF1) and cyclin D proteins cul-1 is required for cell cycle exit in C. elegans and identifies a novel gene family Interaction between ubiquitin-protein ligase SCFSKP2 and E2F-1 underlies the regulation of E2F-1 degradation Identification of the receptor component of the IkappaBalpha-ubiquitin ligase The SCFbeta-TRCP-ubiquitin ligase complex associates specifically with phosphorylated destruction motifs in IkappaBalpha and beta-catenin and stimulates IkappaBalpha ubiquitination in vitro Cdc53p acts in concert with Cdc4p and Cdc34p to control the G1-to-S-phase transition and identifies a conserved family of proteins A complex of Cdc4p, Skp1p, and Cdc53p/cullin catalyzes ubiquitination of the phosphorylated CDK inhibitor Sic1p Reconstitution of G1 cyclin ubiquitination with complexes containing SCFGrr1 and Rbx1. Cdc53 is a scaffold protein for multiple Cdc34/Skp1/F-box proteincomplexes that regulate cell division and methionine biosynthesis in yeast Rbx1, a component of the VHL tumor suppressor complex and SCF ubiquitin ligase Brca2 is required for embryonic cellular proliferation in the mouse p300/MDM2 complexes participate in MDM2-mediated p53 degradation SIC1 is ubiquitinated in vitro by a pathway that requires CDC4, CDC34, and cyclin/CDK activities Association of human CUL-1 and ubiquitin-conjugating enzyme CDC34 with the F-box protein p45(SKP2): evidence for evolutionary conservation in the subunit composition of the CDC34-SCF pathway The human F box protein beta-Trcp associates with the Cul1/Skp1 complex and regulates the stability of beta-catenin. Proteolysis and the G1-S transition: the SCF connection Chronic estrogen-induced cervical and vaginal squamous carcinogenesis in human papillomavirus type 16 transgenic mice Cdc53 targets phosphorylated G1 cyclins for degradation by the ubiquitin proteolytic pathway
author name string	wds:Q28504517-0284F429-DEBB-4546-A8C4-6792FB98CF7D wds:Q28504517-2ABB9986-7334-41E5-BB9B-484CD8E389B1 wds:Q28504517-3B74D141-86E0-4D21-8E3E-56BD2D0723A4 wds:Q28504517-451DDB8B-DD85-4EAF-B38B-DB058867EF93 wds:Q28504517-6A04C620-1925-45AE-A967-B159C0CB6CAA wds:Q28504517-884D07FE-83E3-4434-81D7-33B744CC30BA wds:Q28504517-BAE0E27B-B94B-4DD7-9B03-91F73FD21939 wds:Q28504517-C86B4666-801A-439C-B373-01E518BB4507
OpenCitations bibliographic resource ID	wds:Q28504517-31771EDF-8353-4F96-8606-6BF126C7BFFF
OpenCitations bibliographic resource ID	https://w3id.org/oc/corpus/br/1501098
author name string	Krek W Lo J Gstaiger M Elson D Kipreos ET Arbeit J Dealy MJ Nguyen KV
OpenCitations bibliographic resource ID	1501098
rdfs:label	Loss of Cul1 results in early embryonic lethality and dysregulation of cyclin E (en) Loss of Cul1 results in early embryonic lethality and dysregulation of cyclin E (nl) Loss of Cul1 results in early embryonic lethality and dysregulation of cyclin E (ast)
skos:prefLabel	Loss of Cul1 results in early embryonic lethality and dysregulation of cyclin E (en) Loss of Cul1 results in early embryonic lethality and dysregulation of cyclin E (nl) Loss of Cul1 results in early embryonic lethality and dysregulation of cyclin E (ast)
name	Loss of Cul1 results in early embryonic lethality and dysregulation of cyclin E (en) Loss of Cul1 results in early embryonic lethality and dysregulation of cyclin E (nl) Loss of Cul1 results in early embryonic lethality and dysregulation of cyclin E (ast)
author	wds:Q28504517-C7F67DB3-255E-4D19-AB63-097BB83888BC
author	Randall S. Johnson
title	wds:Q28504517-A4C21839-A765-4F54-9D98-64B4768CAF17
title	Loss of Cul1 results in early embryonic lethality and dysregulation of cyclin E (en)
page(s)	wds:Q28504517-0FCB0D7F-B18A-445A-8D08-E42ED71F9A55
page(s)	245-248
instance of	wds:Q28504517-64709801-EC6C-479A-8D4B-8CF09C8F88C9
instance of	scholarly article

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