About: Degradation of the SCF component Skp2 in cell-cycle phase G1 by the anaphase-promoting complex

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About: Degradation of the SCF component Skp2 in cell-cycle phase G1 by the anaphase-promoting complex Goto Sponge NotDistinct Permalink

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scientific article (publication date: 11 March 2004)

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rdf:type	Item
description	artículu científicu espublizáu en 2004 (ast) vědecký článek publikovaný v roce 2004 (cs) 2004 թվականի մարտին հրատարակված գիտական հոդված (hy) наукова стаття, опублікована в березні 2004 (uk) 2004 թուականի Մարտին հրատարակուած գիտական յօդուած (hyw) vedecký článok (publikovaný 2004/03/11) (sk) مقالة علمية (نشرت في 11-3-2004) (ar) wetenschappelijk artikel (gepubliceerd op 2004/03/11) (nl) article publié dans la revue scientifique Nature (fr) im März 2004 veröffentlichter wissenschaftlicher Artikel (de) scientific article (publication date: 11 March 2004) (en)
publication date	wds:Q28249855-CD83318E-21B9-4088-A2C8-02162CAA8577
publication date	2004-03-11 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q28249855-02514F70-777A-4480-A1CF-37FB61902AC0
language of work or name	English
cites work	wds:Q28249855-052A728F-B244-40D5-BF57-CFCDD0B52DF6 wds:Q28249855-05CBD7EF-C4FA-46B6-BA51-BA5F2319756E wds:Q28249855-1662C767-F349-485A-9F6C-94E98A2C3A0B wds:Q28249855-18A227DF-5757-460B-B3EF-F0BD263948F0 wds:Q28249855-300517B9-0D11-497E-B713-AC7B815EEC4C wds:Q28249855-3898BE22-0A96-44D9-948E-DB2ED8F0FE75 wds:Q28249855-3DDFC8A2-CFD3-4B41-B113-8D8693951938 wds:Q28249855-433E8DBC-216B-45DE-B1BC-C61FA8DBAA01 wds:Q28249855-466B121A-7380-4E0D-9BD6-875F6061131E wds:Q28249855-4F42B780-454A-45B3-B15E-F41AB6711EF4 wds:Q28249855-590C366B-093F-48C7-9A19-E8F7ED57C3F1 wds:Q28249855-65FD3297-CF21-44FB-9318-5F938075CD4A wds:Q28249855-6D7A873F-E478-470D-B36E-FEC79F425AC0 wds:Q28249855-70D9BD01-97D9-43EE-8AE2-48657602939C wds:Q28249855-805633CF-BA6E-4FD7-B05E-F5A3C63A6142 wds:Q28249855-95122A6F-791B-476B-9101-808C770639DA wds:Q28249855-96AAA1B2-9F1B-4A2B-A34A-88A7FBE8D47A wds:Q28249855-AF4EFE5C-AF22-4FFB-90D5-51D1B2C4D839 wds:Q28249855-B56701B3-EFE6-4B88-B029-196F78566F6D wds:Q28249855-C12DBA3F-15F0-4CC3-AAFE-C44BD839CFDE wds:Q28249855-C571E98E-3A53-4717-A695-B250F57293AF wds:Q28249855-D391F13E-6C59-407C-B3E2-058670E30852 wds:Q28249855-D43B2890-07DB-4820-A104-CE5334A0FDAC wds:Q28249855-D7610AEE-B3DF-4161-AA82-A95A0F295B99 wds:Q28249855-DC92B91D-62E9-4545-BF90-B32E239AA90E wds:Q28249855-F624D653-B5DA-4607-9CBE-3335AF16CE46 wds:Q28249855-FC34EA7F-1808-4123-8AED-6AE49E34CE5F
cites work	The anaphase-promoting complex mediates TGF-beta signaling by targeting SnoN for destruction Regulation of the cell cycle at the G1-S transition by proteolysis of cyclin E and p27Kip1. Control of the SCF(Skp2-Cks1) ubiquitin ligase by the APC/C(Cdh1) ubiquitin ligase Dominoes and clocks: the union of two views of the cell cycle Skp2 regulates Myc protein stability and activity p45SKP2 promotes p27Kip1 degradation and induces S phase in quiescent cells The F-box protein Skp2 participates in c-Myc proteosomal degradation and acts as a cofactor for c-Myc-regulated transcription Identification of cellular proteins that can interact specifically with the T/ElA-binding region of the retinoblastoma gene product Substrate recognition by the Cdc20 and Cdh1 components of the anaphase-promoting complex The anaphase-promoting complex: proteolysis in mitosis and beyond Whose end is destruction: cell division and the anaphase-promoting complex The anaphase-promoting complex: it's not just for mitosis any more. Human origin recognition complex large subunit is degraded by ubiquitin-mediated proteolysis after initiation of DNA replication p19Skp1 and p45Skp2 are essential elements of the cyclin A-CDK2 S phase kinase Geminin, an inhibitor of DNA replication, is degraded during mitosis A system for stable expression of short interfering RNAs in mammalian cells A conserved cyclin-binding domain determines functional interplay between anaphase-promoting complex-Cdh1 and cyclin A-Cdk2 during cell cycle progression The F-box protein Skp2 is a ubiquitylation target of a Cul1-based core ubiquitin ligase complex: evidence for a role of Cul1 in the suppression of Skp2 expression in quiescent fibroblasts Nonperiodic activity of the human anaphase-promoting complex-Cdh1 ubiquitin ligase results in continuous DNA synthesis uncoupled from mitosis Role of the F-box protein Skp2 in lymphomagenesis Deregulated degradation of the cdk inhibitor p27 and malignant transformation. Skp2 is oncogenic and overexpressed in human cancers Targeted disruption of Skp2 results in accumulation of cyclin E and p27(Kip1), polyploidy and centrosome overduplication Direct binding of CDC20 protein family members activates the anaphase-promoting complex in mitosis and G1 Induction of hepatocyte proliferation and liver hyperplasia by the targeted expression of cyclin E and skp2 Tome-1, a trigger of mitotic entry, is degraded during G1 via the APC. Yeast Hct1 recognizes the mitotic cyclin Clb2 and other substrates of the ubiquitin ligase APC.
author name string	wds:Q28249855-3D183FEE-1532-4156-9524-DCCFDCD2E07B wds:Q28249855-508FCF88-A2BF-442B-8504-1CAD8BA8F65F wds:Q28249855-9EE4226F-8738-4E82-A1DA-0B32D6A69226 wds:Q28249855-C266EFEE-E877-40E5-B0F6-00C6FCE9788E wds:Q28249855-C2C4E0D1-A0CD-4F83-8E26-8CAC2DFDFC0C
OpenCitations bibliographic resource ID	wds:Q28249855-19F00115-85AD-4A68-A54E-83F7047A60F3
OpenCitations bibliographic resource ID	https://w3id.org/oc/corpus/br/4604998
author name string	Marc W Kirschner Wenyi Wei Nagi G Ayad Yong Wan Guo-Jun Zhang
OpenCitations bibliographic resource ID	4604998
rdfs:label	Degradation of the SCF component Skp2 in cell-cycle phase G1 by the anaphase-promoting complex (en) Degradation of the SCF component Skp2 in cell-cycle phase G1 by the anaphase-promoting complex (nl) Degradation of the SCF component Skp2 in cell-cycle phase G1 by the anaphase-promoting complex (ast)
skos:prefLabel	Degradation of the SCF component Skp2 in cell-cycle phase G1 by the anaphase-promoting complex (en) Degradation of the SCF component Skp2 in cell-cycle phase G1 by the anaphase-promoting complex (nl) Degradation of the SCF component Skp2 in cell-cycle phase G1 by the anaphase-promoting complex (ast)
name	Degradation of the SCF component Skp2 in cell-cycle phase G1 by the anaphase-promoting complex (en) Degradation of the SCF component Skp2 in cell-cycle phase G1 by the anaphase-promoting complex (nl) Degradation of the SCF component Skp2 in cell-cycle phase G1 by the anaphase-promoting complex (ast)
author	wds:Q28249855-031214D6-2328-4F6F-B259-4EE5423FDE73
author	William G. Kaelin
title	wds:Q28249855-90770FC8-C6B4-4C38-B5BF-305F69243E37
title	Degradation of the SCF component Skp2 in cell-cycle phase G1 by the anaphase-promoting complex (en)
page(s)	wds:Q28249855-1B09BFE8-7482-4B39-B310-6C849701DB17
page(s)	194-8
instance of	wds:Q28249855-6CD00EE0-504F-4C1A-A70F-871038588360
instance of	scholarly article

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