About: The orphan receptor C5L2 has high affinity binding sites for complement fragments C5a and C5a des-Arg(74)

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About: The orphan receptor C5L2 has high affinity binding sites for complement fragments C5a and C5a des-Arg(74) Goto Sponge NotDistinct Permalink

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scientific article (publication date: March 2002)

Attributes	Values
rdf:type	Item
description	artículu científicu espublizáu en 2002 (ast) vědecký článek publikovaný v roce 2002 (cs) 2002 թուականի Մարտին հրատարակուած գիտական յօդուած (hyw) 2002 թվականի մարտին հրատարակված գիտական հոդված (hy) наукова стаття, опублікована в березні 2002 (uk) مقالة علمية (نشرت في مارس 2002) (ar) vedecký článok (publikovaný 2002/03/01) (sk) wetenschappelijk artikel (gepubliceerd op 2002/03/01) (nl) scientific article (publication date: March 2002) (en) article publié dans la revue scientifique Journal of Biological Chemistry (fr) im März 2002 veröffentlichter wissenschaftlicher Artikel (de)
publication date	wds:Q28214372-D056863E-EF55-490E-8A30-F272FBD7AB1A
publication date	2001-12-31 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q28214372-4802432A-77E2-4AE2-BFE3-2E011778575D
language of work or name	English
author name string	wds:Q28214372-9F947F40-4CC9-4B8D-B314-6CF27BEB3CD4
OpenCitations bibliographic resource ID	wds:Q28214372-E53CDEC6-6A7D-43ED-92FF-9C7CA36B25B0
OpenCitations bibliographic resource ID	https://w3id.org/oc/corpus/br/2867730
author name string	Stuart A Cain
OpenCitations bibliographic resource ID	2867730
rdfs:label	The orphan receptor C5L2 has high affinity binding sites for complement fragments C5a and C5a des-Arg(74) (en) The orphan receptor C5L2 has high affinity binding sites for complement fragments C5a and C5a des-Arg(74) (nl) The orphan receptor C5L2 has high affinity binding sites for complement fragments C5a and C5a des-Arg(74) (ast)
skos:prefLabel	The orphan receptor C5L2 has high affinity binding sites for complement fragments C5a and C5a des-Arg(74) (en) The orphan receptor C5L2 has high affinity binding sites for complement fragments C5a and C5a des-Arg(74) (nl) The orphan receptor C5L2 has high affinity binding sites for complement fragments C5a and C5a des-Arg(74) (ast)
name	The orphan receptor C5L2 has high affinity binding sites for complement fragments C5a and C5a des-Arg(74) (en) The orphan receptor C5L2 has high affinity binding sites for complement fragments C5a and C5a des-Arg(74) (nl) The orphan receptor C5L2 has high affinity binding sites for complement fragments C5a and C5a des-Arg(74) (ast)
author	wds:Q28214372-1641CC00-98F6-463F-8777-EF81BC1D890A
author	Peter N. Monk
title	wds:Q28214372-D6856338-3C19-42B0-9551-1EDBF896AD97
title	The orphan receptor C5L2 has high affinity binding sites for complement fragments C5a and C5a des-Arg(74) (en)
page(s)	wds:Q28214372-B5DF8157-F9B7-4BFB-A6B7-A0826430FEE8
page(s)	7165-7169
instance of	wds:Q28214372-7B6C2B3C-6F9F-4A83-BDFC-A752EBFB3FB5
instance of	scholarly article
PubMed ID	wds:Q28214372-9E9C66CF-31EA-4B5A-85B1-20FC8B283F65
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/11773063
PubMed ID	11773063
published in	wds:Q28214372-3B4AC4D3-877C-4B94-B550-B364929C2AFC
published in	Journal of Biological Chemistry
issue	wds:Q28214372-D5711EB1-9216-45E6-8119-6741F7E16713
volume	wds:Q28214372-4F92CE14-341B-4059-892C-4A2CCF178A69
issue	9
volume	277
DOI	wds:Q28214372-D709E794-C90D-41F8-98BC-3F84D28F9F5D
DOI	http://dx.doi.org/10.1074/JBC.C100714200
DOI	10.1074/JBC.C100714200
is owl:sameAs of	The orphan receptor C5L2 has high affinity binding sites for complement fragments C5a and C5a des-Arg(74)
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q28214372
is cites work of	C5a and its receptors in human anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis Molecular basis for downregulation of C5a-mediated inflammation by IgG1 immune complexes in allergy and asthma An anti-inflammatory function for the complement anaphylatoxin C5a-binding protein, C5L2 VirD: a virion display array for profiling functional membrane proteins Role of C3a receptors, C5a receptors, and complement protein C6 deficiency in collagen antibody-induced arthritis in mice International Union of Basic and Clinical Pharmacology. [corrected]. LXXXIX. Update on the extended family of chemokine receptors and introducing a new nomenclature for atypical chemokine receptors Complement, c1q, and c1q-related molecules regulate macrophage polarization The C5a receptor (C5aR) C5L2 is a modulator of C5aR-mediated signal transduction. The role of the anaphylatoxins in health and disease Receptors for complement C5a. The importance of C5aR and the enigmatic role of C5L2. Contribution of anaphylatoxins to allergic inflammation in human lungs C5L2 is critical for the biological activities of the anaphylatoxins C5a and C3a Complement System Part II: Role in Immunity Complement System Part I - Molecular Mechanisms of Activation and Regulation Functions of C5a receptors Diabetes, lipids, and adipocyte secretagogues Function, structure and therapeutic potential of complement C5a receptors The N-formyl peptide receptors and the anaphylatoxin C5a receptors: an overview The complement system The chemoattractant receptor-like protein C5L2 binds the C3a des-Arg77/acylation-stimulating protein The human complement fragment receptor, C5L2, is a recycling decoy receptor. C5L2 receptor is not involved in C3a / C3a-desArg-mediated enhancement of bone marrow hematopoietic cell migration to CXCL12 The Concise Guide to PHARMACOLOGY 2013/14: G protein-coupled receptors Complement activation in the injured central nervous system: another dual-edged sword? Smoke and C5a Induce Airway Epithelial Intercellular Adhesion Molecule-1 and Cell Adhesion G protein-coupled receptor genes in the FANTOM2 database Extracellular histones are essential effectors of C5aR- and C5L2-mediated tissue damage and inflammation in acute lung injury C5a mutants are potent antagonists of the C5a receptor (CD88) and of C5L2: position 69 is the locus that determines agonism or antagonism Functional roles for C5a and C5aR but not C5L2 in the pathogenesis of human and experimental cerebral malaria Anaphylatoxins: their role in bacterial infection and inflammation De novo peptide design with C3a receptor agonist and antagonist activities: theoretical predictions and experimental validation Neutralizing endogenous chemokines with small molecules. Principles and potential therapeutic applications. C5a receptor-deficient dendritic cells promote induction of Treg and Th17 cells C5a/C5aR pathway is essential for the pathogenesis of murine viral fulminant hepatitis by way of potentiating Fgl2/fibroleukin expression Functional roles for C5a receptors in sepsis Locally produced complement fragments C5a and C3a provide both costimulatory and survival signals to naive CD4+ T cells The role of the ribosomal protein S19 C-terminus in altering the chemotaxis of leucocytes by causing functional differences in the C5a receptor response Absence of signaling into CD4⁺ cells via C3aR and C5aR enables autoinductive TGF-β1 signaling and induction of Foxp3⁺ regulatory T cells. Complement activation product C5a is a selective suppressor of TLR4-induced, but not TLR3-induced, production of IL-27(p28) from macrophages C5a receptor-dependent cell activation by physiological concentrations of desarginated C5a: insights from a novel label-free cellular assay The role of complement in danger sensing and transmission Complement in allergy and asthma Pre-neutralization of C5a-mediated effects by the monoclonal antibody 137-26 reacting with the C5a moiety of native C5 without preventing C5 cleavage. The harmful role of c5a on innate immunity in sepsis Recent developments in low molecular weight complement inhibitors Enhancement of in vivo and in vitro immune functions by a conformationally biased, response-selective agonist of human C5a: implications for a novel adjuvant in vaccine design Atypical chemokine receptors: from silence to sound. The role of the complement system and the activation fragment C5a in the central nervous system

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