About: miR-1 overexpression enhances Ca(2+) release and promotes cardiac arrhythmogenesis by targeting PP2A regulatory subunit B56alpha and causing CaMKII-dependent hyperphosphorylation of RyR2

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About: miR-1 overexpression enhances Ca(2+) release and promotes cardiac arrhythmogenesis by targeting PP2A regulatory subunit B56alpha and causing CaMKII-dependent hyperphosphorylation of RyR2 Goto Sponge NotDistinct Permalink

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description	artículu científicu espublizáu en 2009 (ast) vědecký článek publikovaný v roce 2009 (cs) 2009 թուականի Փետրուարին հրատարակուած գիտական յօդուած (hyw) 2009 թվականի փետրվարին հրատարակված գիտական հոդված (hy) наукова стаття, опублікована в лютому 2009 (uk) vedecký článok (publikovaný 2009/02/27) (sk) im Februar 2009 veröffentlichter wissenschaftlicher Artikel (de) wetenschappelijk artikel (gepubliceerd op 2009/02/27) (nl) مقالة علمية (نشرت في 27-2-2009) (ar) scientific journal article (en)
publication date	wds:Q28117385-F393ABB0-0CC2-4166-8003-26A8DAEE2B49
publication date	2009-02-27 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q28117385-984028DF-76A9-40A0-9529-AE04CDC74D7E
language of work or name	English
cites work	wds:Q28117385-092F5680-C061-41D4-9E4C-71B5EF46F851 wds:Q28117385-0CE825D7-5911-471E-9425-7F49A2448194 wds:Q28117385-1E4BB2F0-7535-43CF-82F6-CBF68F480EAD wds:Q28117385-4E92B45D-28CB-462E-A2E1-A3C42194A116 wds:Q28117385-51D89DD0-5351-4A7E-98DD-4E12E4908658 wds:Q28117385-5268A1EF-0341-4B4F-AFC8-AED34CA396F1 wds:Q28117385-5AABC86E-FA84-4E75-B23E-09DB8E07F08A wds:Q28117385-6027C0EC-3F49-4B76-B2CB-D65877A7E2A6 wds:Q28117385-65689488-749E-4725-B533-4F587A67F421 wds:Q28117385-659EC115-6F11-48CD-9860-9568A99CEF06 wds:Q28117385-66070E44-B090-49A0-A271-5831274AFCEC wds:Q28117385-6A74074B-D059-410A-9698-C6DDAC8BAAA5 wds:Q28117385-6E7F366B-0A94-4FC8-9069-3B8E55A9999C wds:Q28117385-78BC8413-249C-432C-B17A-8B2361A50F77 wds:Q28117385-85D0E870-3D14-42CC-AF07-0D6ACEE5001D wds:Q28117385-894A2407-1923-457B-A642-1A4D30D9C83C wds:Q28117385-910C354A-7D4D-40D9-9CCA-6A8ACA0105B4 wds:Q28117385-9119B5DE-119C-4914-BCCA-B6340AFB8B14 wds:Q28117385-9498EB08-777A-44AB-9310-50CFB3A72B6F wds:Q28117385-9931AE12-42A3-4739-B139-9531900EC49F wds:Q28117385-9A7B6065-0A53-4336-BE74-CB4207AAA692 wds:Q28117385-9D5C9150-CB3B-4CD0-A562-4C70BD1D3235 wds:Q28117385-A7DF0289-FC1D-4A29-9A0D-230829E587D7 wds:Q28117385-AA29BF3E-4CFF-450D-8005-5C371471B823 wds:Q28117385-BD7403DB-6EC1-4640-A754-F103B4FEB121 wds:Q28117385-BF65969B-1283-40BC-A67A-826528CA25E7 wds:Q28117385-BF6AE81B-C6C2-4DB6-9C2E-B73FAD78B696 wds:Q28117385-CD1BC35B-0EFB-4073-9901-7550D171C9B6 wds:Q28117385-D5BE6312-7D2C-483D-AB2A-87CDFD5C48E8 wds:Q28117385-E204164A-629D-4C25-A8FA-4CCB995EAE79 wds:Q28117385-E2564803-3518-4CDF-9BC2-F7E64D57F40B wds:Q28117385-E7B45E5B-2243-4A96-A747-2BE9A9CC660C wds:Q28117385-E828D132-46C0-4BC4-9C66-1F65D13F6204 wds:Q28117385-EECE29D7-E687-40C0-A8FC-2E0F35EB66FD wds:Q28117385-F7AC517C-0EAA-4BD8-8E65-356097F7C7CF wds:Q28117385-FCAFD293-03C4-44EF-80E1-7CDCC428ABF2 wds:Q28117385-FFACD2EE-AA8C-419D-AAEF-465FD30F64D8
cites work	Role of Ca2+/calmodulin-dependent protein kinase (CaMK) in excitation-contraction coupling in the heart Intact beta-adrenergic response and unmodified progression toward heart failure in mice with genetic ablation of a major protein kinase A phosphorylation site in the cardiac ryanodine receptor MicroRNAs in the human heart: a clue to fetal gene reprogramming in heart failure Ca2+/calmodulin-dependent protein kinase modulates cardiac ryanodine receptor phosphorylation and sarcoplasmic reticulum Ca2+ leak in heart failure The muscle-specific microRNA miR-1 regulates cardiac arrhythmogenic potential by targeting GJA1 and KCNJ2 Time and calcium dependence of activation and inactivation of calcium-induced release of calcium from the sarcoplasmic reticulum of a skinned canine cardiac Purkinje cell Binding of protein phosphatase 2A to the L-type calcium channel Cav1.2 next to Ser1928, its main PKA site, is critical for Ser1928 dephosphorylation MicroRNAs: genomics, biogenesis, mechanism, and function Serum response factor regulates a muscle-specific microRNA that targets Hand2 during cardiogenesis Cardiac excitation-contraction coupling The phospholamban phosphatase associated with cardiac sarcoplasmic reticulum is a type 1 enzyme Molecular basis for PP2A regulatory subunit B56alpha targeting in cardiomyocytes A cardiac arrhythmia syndrome caused by loss of ankyrin-B function Sudden death in familial polymorphic ventricular tachycardia associated with calcium release channel (ryanodine receptor) leak Sarcoplasmic reticulum Ca2+ and heart failure: roles of diastolic leak and Ca2+ transport Ryanodine receptor-ankyrin interaction regulates internal Ca2+ release in mouse T-lymphoma cells MicroRNAs play an essential role in the development of cardiac hypertrophy Fluctuations in membrane current driven by intracellular calcium in cardiac Purkinje fibers Characterization of a novel PKA phosphorylation site, serine-2030, reveals no PKA hyperphosphorylation of the cardiac ryanodine receptor in canine heart failure. Calmodulin kinase II and arrhythmias in a mouse model of cardiac hypertrophy Ankyrin-B mutation causes type 4 long-QT cardiac arrhythmia and sudden cardiac death Arrhythmogenesis and contractile dysfunction in heart failure: Roles of sodium-calcium exchange, inward rectifier potassium current, and residual beta-adrenergic responsiveness Emerging role of microRNAs in cardiovascular biology. Ca2+/calmodulin kinase II-dependent phosphorylation of ryanodine receptors suppresses Ca2+ sparks and Ca2+ waves in cardiac myocytes PKA phosphorylation dissociates FKBP12.6 from the calcium release channel (ryanodine receptor): defective regulation in failing hearts Stoichiometric phosphorylation of cardiac ryanodine receptor on serine 2809 by calmodulin-dependent kinase II and protein kinase A. Protein phosphatase 2A is associated with class C L-type calcium channels (Cav1.2) and antagonizes channel phosphorylation by cAMP-dependent protein kinase Ca2+/calmodulin-dependent protein kinase II phosphorylation regulates the cardiac ryanodine receptor Phosphorylation-dependent regulation of ryanodine receptors: a novel role for leucine/isoleucine zippers Transformation of adult rat cardiac myocytes in primary culture Ser1928 is a common site for Cav1.2 phosphorylation by protein kinase C isoforms CaMKII, an emerging molecular driver for calcium homeostasis, arrhythmias, and cardiac dysfunction. Increasing Ryanodine Receptor Open Probability Alone Does Not Produce Arrhythmogenic Calcium Waves What are the consequences of phosphorylation and hyperphosphorylation of ryanodine receptors in normal and failing heart? Protein phosphatases decrease sarcoplasmic reticulum calcium content by stimulating calcium release in cardiac myocytes miRNAs at the heart of the matter Novel therapeutic approaches for heart failure by normalizing calcium cycling
author name string	wds:Q28117385-1E3C4DD8-81F4-4111-AF36-BE9DE9ADEA49 wds:Q28117385-2B0AD7CF-8473-404C-A3A2-EA2003A50562 wds:Q28117385-342E84DE-0B95-4BC1-AA07-D6829BE4D93D wds:Q28117385-3E748DBE-CC28-4ADC-A28C-5C525FBE4B5B wds:Q28117385-508FA021-9116-40C0-A2A6-EA37DA465C08 wds:Q28117385-5FC30581-35CE-4900-B4ED-BA661FD300D6 wds:Q28117385-7D025C92-9F29-4B11-A789-376D36040038 wds:Q28117385-8A123110-C470-41A5-BF22-2E695BCB9F93 wds:Q28117385-CA4FEBA9-0FFF-4E20-9C96-9D2A5A65F1C5 wds:Q28117385-DC85AB46-1893-4638-B95D-ECABB379490E
OpenCitations bibliographic resource ID	wds:Q28117385-440E14FD-1A30-4D25-B034-F2D390E9DBF4

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