About: Abelson-interactor-1 promotes WAVE2 membrane translocation and Abelson-mediated tyrosine phosphorylation required for WAVE2 activation

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scientific journal article

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rdf:type	Item
description	artículu científicu espublizáu en 2005 (ast) vědecký článek publikovaný v roce 2005 (cs) 2005 թուականի Յունուարին հրատարակուած գիտական յօդուած (hyw) 2005 թվականի հունվարին հրատարակված գիտական հոդված (hy) наукова стаття, опублікована в січні 2005 (uk) vedecký článok (publikovaný 2005/01/25) (sk) wetenschappelijk artikel (gepubliceerd op 2005/01/25) (nl) مقالة علمية (نشرت في 25-1-2005) (ar) im Januar 2005 veröffentlichter wissenschaftlicher Artikel (de) article publié dans les Proceedings of the National Academy of Sciences of the United States of America (fr) scientific journal article (en) 科學期刊文章 (zh)
publication date	wds:Q28116257-5A247C87-699A-4636-8F94-FB19C3923F31
publication date	2005-01-25 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q28116257-3D86B9D2-40FE-4052-898A-7D6D222EAB23
language of work or name	English
cites work	wds:Q28116257-052EDBA7-ACD6-4FB1-8B09-C3E943DAB8C1 wds:Q28116257-06195DD3-D76E-48D2-9D95-81F57A983FA9 wds:Q28116257-159D7CA3-80AE-472E-B5AB-286D81D71ED5 wds:Q28116257-1CA4ACB8-13F1-45BD-ACCF-6B7447D9A021 wds:Q28116257-29E57FB1-3020-4372-81BA-48CB1519FC24 wds:Q28116257-31EFA690-A214-4C3D-8B29-B7332967C079 wds:Q28116257-3AD5BD4C-678C-49DF-BF92-68F1AF66FB20 wds:Q28116257-45B06DC4-18C2-49F3-A654-4CC93F91A5EF wds:Q28116257-4A02FAE2-F17D-44BE-91EA-68482F395C3C wds:Q28116257-544672D7-F065-4EFF-B970-6A618046D947 wds:Q28116257-5A33325D-97F2-4787-B465-CBAF9E2991B8 wds:Q28116257-5E731C27-A6E0-4EE5-85DE-05DCCBE639D7 wds:Q28116257-6CD387B8-F9C6-454F-AD50-E1C6AFBDF189 wds:Q28116257-8ABBD6FC-4E27-4499-9194-2CD932888E9C wds:Q28116257-8F44E48A-948E-49FA-A21F-FD67E1E181C8 wds:Q28116257-A13FBC32-737A-461E-9F6D-E8DA9AC0577C wds:Q28116257-A68A8435-FD87-49B5-8D0C-A4E8BBF0A84A wds:Q28116257-C3FDCB32-B94D-4ABC-9A57-7ACF86B71FE0 wds:Q28116257-CDF551B6-F560-4657-B846-4A068F54F412 wds:Q28116257-D362197A-26F8-4706-929D-50772F8222D7 wds:Q28116257-DD2E2FCD-C649-4068-BACB-9547E90B75A4 wds:Q28116257-E78B007B-07B0-488C-B93F-0E4B46ABAD4D wds:Q28116257-E94223B6-61B9-4498-8338-E8EB21231868 wds:Q28116257-ED22BBE0-AC1D-44D9-A54C-A33B33AC57CC
cites work	A conserved binding motif defines numerous candidate target proteins for both Cdc42 and Rac GTPases Essential roles for the Abl and Arg tyrosine kinases in neurulation WIP, a protein associated with wiskott-aldrich syndrome protein, induces actin polymerization and redistribution in lymphoid cells The essential role of profilin in the assembly of actin for microspike formation WAVE, a novel WASP-family protein involved in actin reorganization induced by Rac Abl-dependent tyrosine phosphorylation of Sos-1 mediates growth-factor-induced Rac activation N-WASP, a novel actin-depolymerizing protein, regulates the cortical cytoskeletal rearrangement in a PIP2-dependent manner downstream of tyrosine kinases Integration of multiple signals through cooperative regulation of the N-WASP-Arp2/3 complex Two GTPases, Cdc42 and Rac, bind directly to a protein implicated in the immunodeficiency disorder Wiskott-Aldrich syndrome Abl-interactor-1, a novel SH3 protein binding to the carboxy-terminal portion of the Abl protein, suppresses v-abl transforming activity Proper sorting of the cation-dependent mannose 6-phosphate receptor in endosomes depends on a pair of aromatic amino acids in its cytoplasmic tail IRSp53 is an essential intermediate between Rac and WAVE in the regulation of membrane ruffling Cdc42 induces filopodia by promoting the formation of an IRSp53:Mena complex Mechanism of regulation of WAVE1-induced actin nucleation by Rac1 and Nck Abi1 is essential for the formation and activation of a WAVE2 signalling complex Scar1 and the related Wiskott-Aldrich syndrome protein, WASP, regulate the actin cytoskeleton through the Arp2/3 complex Sra-1 and Nap1 link Rac to actin assembly driving lamellipodia formation. Purification and architecture of the ubiquitous Wave complex The Wiskott-Aldrich syndrome protein acts downstream of CD2 and the CD2AP and PSTPIP1 adaptors to promote formation of the immunological synapse Fyn and PTP-PEST-mediated regulation of Wiskott-Aldrich syndrome protein (WASp) tyrosine phosphorylation is required for coupling T cell antigen receptor engagement to WASp effector function and T cell activation Involvement of the Wiskott-Aldrich syndrome protein and other actin regulatory adaptors in T cell activation Wiskott-Aldrich syndrome protein is associated with the adapter protein Grb2 and the epidermal growth factor receptor in living cells The Abl interactor proteins localize to sites of actin polymerization at the tips of lamellipodia and filopodia EPS8 and E3B1 transduce signals from Ras to Rac
author name string	wds:Q28116257-0654037F-62C3-4D1B-8A1A-60CB62BF7067 wds:Q28116257-35769DCD-B43F-4F80-B736-16A68BEC655D wds:Q28116257-46921C6C-1AA5-4A69-A786-4F83F6305CEF wds:Q28116257-56132464-54E4-45F7-87EB-14FE21FA07B9 wds:Q28116257-683CAD47-0CCC-4DC6-9D03-FEF92F34C00F wds:Q28116257-B01A5332-DF0F-4205-9DD5-A226602EA93E wds:Q28116257-E24DCC06-4F48-4C37-BEF6-6AB1D4704955 wds:Q28116257-E75B6814-B752-4DFD-AE27-AD7A4F20B1AE
author name string	Jinyi Zhang Karen Badour Spencer Freeman Michael Siu Katherine Siminovitch Yan Leng Enrico Arpaia Pam Cheung
rdfs:label	Abelson-interactor-1 promotes WAVE2 membrane translocation and Abelson-mediated tyrosine phosphorylation required for WAVE2 activation (en) Abelson-interactor-1 promotes WAVE2 membrane translocation and Abelson-mediated tyrosine phosphorylation required for WAVE2 activation (nl) Abelson-interactor-1 promotes WAVE2 membrane translocation and Abelson-mediated tyrosine phosphorylation required for WAVE2 activation (ast)
skos:prefLabel	Abelson-interactor-1 promotes WAVE2 membrane translocation and Abelson-mediated tyrosine phosphorylation required for WAVE2 activation (en) Abelson-interactor-1 promotes WAVE2 membrane translocation and Abelson-mediated tyrosine phosphorylation required for WAVE2 activation (nl) Abelson-interactor-1 promotes WAVE2 membrane translocation and Abelson-mediated tyrosine phosphorylation required for WAVE2 activation (ast)
name	Abelson-interactor-1 promotes WAVE2 membrane translocation and Abelson-mediated tyrosine phosphorylation required for WAVE2 activation (en) Abelson-interactor-1 promotes WAVE2 membrane translocation and Abelson-mediated tyrosine phosphorylation required for WAVE2 activation (nl) Abelson-interactor-1 promotes WAVE2 membrane translocation and Abelson-mediated tyrosine phosphorylation required for WAVE2 activation (ast)
title	wds:Q28116257-129D6809-831A-442C-AC45-6AEDA4E39386
title	Abelson-interactor-1 promotes WAVE2 membrane translocation and Abelson-mediated tyrosine phosphorylation required for WAVE2 activation (en)
page(s)	wds:Q28116257-ABFB581F-7CFF-44F9-8E40-492C2FFE762A
page(s)	1098–1103
instance of	wds:Q28116257-2B31B7EC-DB4D-458C-83BD-7B7AF6050653
instance of	scholarly article
main subject	wds:Q28116257-7D31F765-E380-498E-BF7F-E130248B1B2B wds:Q28116257-C3898DB2-DCCB-425D-A38B-62C81B592907 wds:Q28116257-ED397B7C-EBCF-4E4C-B304-1E394625E568
main subject	phosphorylation

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