About: nuclear exosome (RNase complex)

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A ribonuclease complex that has 3-prime to 5-prime processive and distributive hydrolytic exoribonuclease activity and endoribonuclease activity, producing 5-prime-phosphomonoesters. Participates in a multitude of cellular RNA processing and degradat

Attributes	Values
rdf:type	Item
description	cellulaire component (nl) A ribonuclease complex that has 3-prime to 5-prime processive and distributive hydrolytic exoribonuclease activity and endoribonuclease activity, producing 5-prime-phosphomonoesters. Participates in a multitude of cellular RNA processing and degradat (en)
exact match	wds:Q21112786-43D19A2B-F3DC-421C-A8D3-7D6297759556
exact match	http://purl.obolibrary.org/obo/GO_0000176
rdfs:label	nuclear exosome (RNase complex) (en)
skos:prefLabel	nuclear exosome (RNase complex) (en)
name	nuclear exosome (RNase complex) (en)
Gene Ontology ID	wds:Q21112786-A5526861-07CF-4DE1-9466-5958A33563EA
Gene Ontology ID	GO:0000176
instance of	wds:Q21112786-FBC964CE-3864-4EF3-8678-2F103A22A392
part of	wds:Q21112786-F66EB1C4-F62D-434A-BAE9-F6E228BA513B
instance of	cellular component
part of	nuclear lumen
subclass of	wds:Q21112786-D1D6FE42-1807-4DEE-9A34-70A757B8B26A wds:Q21112786-D53939A6-DB8F-4E17-97AF-A5002B322C8E
subclass of	exosome (RNase complex) nuclear protein-containing complex
skos:altLabel	GO:0000176 (en) nuclear exosome (ribonuclease complex) (en) nuclear exosome multienzyme ribonuclease complex (en) eukaryotic exosome multienzyme ribonuclease complex (en)
UMLS CUI	wds:Q21112786-35BE3904-D07B-4B67-B19D-E6C281D254CE
UMLS CUI	C1167051
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q21112786
is subclass of of	Nuclear exosome complex, Dis3-Exosc10 variant nucleolar exosome (RNase complex) Nuclear exosome complex, DIS3-EXOSC10 variant
is subclass of of	wds:Q107602662-8D9F6C78-24BD-40B4-9796-CDE5DE5517FD wds:Q26481959-03655967-1AD7-4F52-BA16-0AFC7260BA71 wds:Q107514712-C98616EC-9016-4022-BF30-14F001131646
is has part(s) of	nuclear exosome focus
is main subject of	The regulation and functions of the nuclear RNA exosome complex. Reconstitution, activities, and structure of the eukaryotic RNA exosome The human core exosome interacts with differentially localized processive RNases: hDIS3 and hDIS3L
is has part(s) of	wds:Q22328740-CC5F4FD4-BC4B-438F-88AF-BAADB365C4C9
is main subject of	wds:Q38685674-37D4B93C-4907-40DE-9DB0-A6301E140BFD wds:Q24337238-F0766265-ECEB-4874-B915-8318AB92E8EB wds:Q24317597-60484411-DC6F-4742-B13E-BAEC2BA990D0
is cell component of	wd:Q5420679 C1D nuclear receptor corepressor Mtr4 exosome RNA helicase M-phase phosphoprotein 6 Exosome catalytic subunit DIS3 YOL021C Mtr4 exosome RNA helicase Exosome component 2 Nuclear VCP like WD repeat domain 74 Exosome component 4 Lrp1p YHR081W Mpp6p YNR024W Exosome component 9 Exosome component 10 Exosome non-catalytic core subunit RRP40 YOL142W Karyopherin alpha YNL189W Exosome component 6 Dis3 Dmel_CG6413 Exosome component 8 Exosome component 2 Karyopherin beta YLR347C Exosome component 9 Spt5 Dmel_CG7626 Exosome non-catalytic core subunit RRP45 YDR280W Exosome non-catalytic core subunit CSL4 YNL232W Exosome non-catalytic core subunit RRP4 YHR069C Exosome non-catalytic core subunit RRP42 YDL111C Exosome non-catalytic core subunit MTR3 YGR158C Exosome non-catalytic core subunit SKI6 YGR195W Exosome nuclease subunit RRP6 YOR001W Exosome non-catalytic core subunit RRP43 YCR035C Exosome non-catalytic core subunit RRP46 YGR095C Spt6 Dmel_CG12225 DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease ribosomal RNA processing protein 6 exosome complex exonuclease, putative exosome complex exonuclease exosome-associated protein 4, putative exosome-associated protein 2, putative ribosomal RNA processing protein 4 exosome-associated protein 2, putative hypothetical protein, conserved ribosomal RNA processing protein 6, putative ribosomal RNA processing protein 45 Exosome component 5 DIS3 like exosome 3'-5' exoribonuclease Exosome component 3 Exosome component 4 Exosome component 7 Exosome component 1 Exosome component 9 exosome-associated protein 4 Rrp45 Dmel_CG9606 Ski6 Dmel_CG15481 Mtr3 Dmel_CG8025 Rrp4 Dmel_CG3931 Csl4 Dmel_CG6249 Rrp42 Dmel_CG8395 Rrp46 Dmel_CG4043 Ribosomal RNA processing 40 Dmel_CG31938 Exosome component 3

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