About: EKC/KEOPS complex

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About: EKC/KEOPS complex Goto Sponge NotDistinct Permalink

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A protein complex involved in t6A tRNA modification; originally proposed to be involved in transcription as well as promoting telomere uncapping and telomere elongation. For example, in Saccharomyces cerevisiae the complex contains Bud32p, Kae1p, Gon

Attributes	Values
rdf:type	Item
description	cellulaire component (nl) A protein complex involved in t6A tRNA modification; originally proposed to be involved in transcription as well as promoting telomere uncapping and telomere elongation. For example, in Saccharomyces cerevisiae the complex contains Bud32p, Kae1p, Gon (en)
exact match	wds:Q21111837-F23D2A20-7B37-4B41-9183-6221A99C9E9A
exact match	http://purl.obolibrary.org/obo/GO_0000408
rdfs:label	EKC/KEOPS complex (en)
skos:prefLabel	EKC/KEOPS complex (en)
name	EKC/KEOPS complex (en)
Gene Ontology ID	wds:Q21111837-FC1A7DC3-7BA3-416E-B16E-DA09EBB2F047
Gene Ontology ID	GO:0000408
instance of	wds:Q21111837-A003B82D-9D30-4927-8ACE-7DE74BFF45F9
instance of	cellular component
subclass of	wds:Q21111837-248D8F88-77B3-440A-83AB-B729B1B4EE68
subclass of	protein-containing complex
skos:altLabel	kinase, putative endopeptidase and other proteins of small size protein complex (en) Kinase, putative Endopeptidase and Other Proteins of Small size protein complex (en) GO:0000408 (en) KEOPS/EKC complex (en) Endopeptidase-like Kinase Chromatin-associated protein complex (en) endopeptidase-like kinase chromatin-associated protein complex (en)
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q21111837
is subclass of of	KEOPS tRNA N6-adenosine threonylcarbamoyltransferase complex KEOPS complex YgjD-YeaZ-YjeE complex
is subclass of of	wds:Q119730049-63C1D6ED-BE8A-467E-9313-4739D6B8B438 wds:Q107314296-85D9C205-FC62-455B-B49C-73F66F6FBCFF wds:Q107601637-31DCB2F0-1C42-4588-8743-260548829540
is main subject of	Mutations in KEOPS-complex genes cause nephrotic syndrome with primary microcephaly. Functional assignment of KEOPS/EKC complex subunits in the biosynthesis of the universal t6A tRNA modification The highly conserved KEOPS/EKC complex is essential for a universal tRNA modification, t6A. Yeast homolog of a cancer-testis antigen defines a new transcription complex A genome-wide screen identifies the evolutionarily conserved KEOPS complex as a telomere regulator
is main subject of	wds:Q27932308-D88C0406-F8B2-42E5-B75F-F4072EB85CA1 wds:Q27933400-C4EAD782-E862-419B-8EDF-2D2755CA3271 wds:Q27938839-DD28C6AC-B5F7-4B17-93DC-A341A1B29BB1 wds:Q27933516-6ACEB2E3-C385-43D3-B7E5-78279A096E69 wds:Q40094779-b49bdd19-46a6-cacd-a2a6-e9a6beeb80c0
is cell component of	TP53-regulating kinase O-sialoglycoprotein endopeptidase Rv3419c EKC/KEOPS complex subunit CGI121 L antigen family, member 3 Hypothetical protein spr0129 GON7 subunit of KEOPS complex O-sialoglycoprotein endopeptidase-like 1 O-sialoglycoprotein endopeptidase CT_343 Tp53rk binding protein Hypothetical protein HI0388 Peptidase M22 family non-proteolytic protein CBU_1371 Hypothetical protein XCC2929 GON7 subunit of KEOPS complex TP53 regulating kinase Peptidase M22 glycoprotease Caur_1990 DNA-binding/iron metalloprotein/AP endonuclease lmo2075 DNA-binding/iron metalloprotein/AP endonuclease SCO4752 DNA-binding/iron metalloprotein/AP endonuclease aq_801 DNA-binding/iron metalloprotein/AP endonuclease NMB1802 Probable tRNA N6-adenosine threonylcarbamoyltransferase L antigen family, member 3 Glycoprotein endopeptidase THEYE_A0583 O-sialoglycoprotein endopeptidase THEYE_A1062 Serine/threonine protein kinase BUD32 YGR262C Si:dkeyp-55f12.3 O-sialoglycoprotein endopeptidase FN0928 tRNA N6-adenosine threonylcarbamoyltransferase, putative EgrG_000105300.1 O-sialoglycoprotein endopeptidase L antigen family member 3 tRNA N6-adenosine threonylcarbamoyltransferase TRNA N6-adenosine threonylcarbamoyltransferase CT_197 Glycoprotease family metalloendopeptidase Caur_0927 DNA-binding/iron metalloprotein/AP endonuclease SAOUHSC_02277 Predicted gene 20604 EKC/KEOPS complex subunit BUD32 O-sialoglycoprotein endopeptidase-like 1 Hypothetical protein DR_0756 DNA-binding/iron metalloprotein/AP endonuclease gll1354 Transformation related protein 53 regulating kinase A Nucleoid maintenance protease YeaZ GSU1913 TRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex dimerization subunit type 1 TsaB STM1820 DNA-binding/iron metalloprotein/AP endonuclease FN0549 TRNA(NNU) t(6)A37 threonylcarbamoyladenosine modification; glycation binding protein BSU_05940 Bll0799 Glycoprotease family protein BC0287 DNA-binding/iron metalloprotein/AP endonuclease CBO3313 DNA-binding/iron metalloprotein/AP endonuclease LA_1450 Chromatin DNA-binding EKC/KEOPS complex subunit GON7 YJL184W TP53 regulating kinase O-sialoglycoprotein endopeptidase-like 1 TRNA N6-adenosine threonylcarbamoyltransferase YKR038C P53-related protein kinase Dmel_CG10673 Probable tRNA N6-adenosine threonylcarbamoyltransferase CELE_Y71H2AM.1 O-sialoglycoprotein endopeptidase TP53 regulating kinase Tcs3 Dmel_CG4933 TRNA N6-adenosine threonylcarbamoyltransferase PA0580 TRNA threonylcarbamoyl adenosine modification protein TsaD STM3208 Putative N(6)-L-threonylcarbamoyladenine synthase YDL104C Essential endopeptidase YgiD SO_1289 Glycoprotease lmo2077 Uncharacterized protein Dmel_CG14231

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