About: insulin secretion involved in cellular response to glucose stimulus

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About: insulin secretion involved in cellular response to glucose stimulus Goto Sponge NotDistinct Permalink

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The regulated release of proinsulin from secretory granules (B granules) in the B cells of the pancreas; accompanied by cleavage of proinsulin to form mature insulin, in response to a glucose stimulus.

Attributes	Values
rdf:type	Item
description	biologisch proces (nl) біологічний процес (uk) The regulated release of proinsulin from secretory granules (B granules) in the B cells of the pancreas; accompanied by cleavage of proinsulin to form mature insulin, in response to a glucose stimulus. (en)
exact match	wds:Q21108800-BDEB751E-CB14-4B95-8565-2C0C2ACBE689
exact match	http://purl.obolibrary.org/obo/GO_0035773
rdfs:label	insulin secretion involved in cellular response to glucose stimulus (en) sekrecija inzulina, ki je vključena v celični odziv na dražljaj glukoze (sl)
skos:prefLabel	insulin secretion involved in cellular response to glucose stimulus (en) sekrecija inzulina, ki je vključena v celični odziv na dražljaj glukoze (sl)
name	insulin secretion involved in cellular response to glucose stimulus (en) sekrecija inzulina, ki je vključena v celični odziv na dražljaj glukoze (sl)
Gene Ontology ID	wds:Q21108800-0032B35E-147A-4B61-8422-4C9F29629E4E
Gene Ontology ID	GO:0035773
instance of	wds:Q21108800-895EFBA5-452E-4AEF-B6FA-56DB9771F06C
part of	wds:Q21108800-6C69106E-8F40-4980-819F-75CBC91CBFD6
instance of	biological process
part of	cellular response to glucose stimulus
subclass of	wds:Q21108800-61C6E28A-A2DC-4D3D-95C5-90C3EB460860 wds:Q21108800-7ED26E5F-39C4-4809-9FBB-774234400D23
subclass of	insulin secretion establishment of localization in cell
skos:altLabel	insulin secretion involved in cellular response to glucose (en) GO:0035773 (en) glucose-induced insulin secretion (en)
UMLS CUI	wds:Q21108800-E44FA064-83A6-441C-A650-BA7ECA190552
UMLS CUI	C3158960
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q21108800
is main subject of	Increasing uncoupling protein-2 in pancreatic beta cells does not alter glucose-induced insulin secretion but decreases production of reactive oxygen species. Impairment of glucose-induced insulin secretion in human pancreatic islets transplanted to diabetic nude mice Glucose-induced insulin secretion is impaired and insulin-induced phosphorylation of the insulin receptor and insulin receptor substrate-1 are increased in protein-deficient rats Modulation of Glucose-Induced Insulin Secretion from a Rat Clonal β-Cell Line* NADH shuttle system regulates K(ATP) channel-dependent pathway and steps distal to cytosolic Ca(2+) concentration elevation in glucose-induced insulin secretion Overexpression of KLF15 transcription factor in adipocytes of mice results in down-regulation of SCD1 protein expression in adipocytes and consequent enhancement of glucose-induced insulin secretion PKClambda regulates glucose-induced insulin secretion through modulation of gene expression in pancreatic beta cells Long-term exposure of rat pancreatic islets to fatty acids inhibits glucose-induced insulin secretion and biosynthesis through a glucose fatty acid cycle Two abnormalities of glucose-induced insulin secretion: dose-response characteristics and insulin sensitivity RANTES (CCL5) reduces glucose-dependent secretion of glucagon-like peptides 1 and 2 and impairs glucose-induced insulin secretion in mice The nuclear orphan receptor Nur77 is a lipotoxicity sensor regulating glucose-induced insulin secretion in pancreatic β-cells Suppression of sulfonylurea- and glucose-induced insulin secretion in vitro and in vivo in mice lacking the chloride transport protein ClC-3. Islet-enriched gene expression and glucose-induced insulin secretion in human and mouse islets Low-density lipoprotein receptor-related protein 5 (LRP5) is essential for normal cholesterol metabolism and glucose-induced insulin secretion Limited role for SREBP-1c in defective glucose-induced insulin secretion from Zucker diabetic fatty rat islets: a functional and gene profiling analysis Uncoupling protein 2: a possible link between fatty acid excess and impaired glucose-induced insulin secretion? Long-term exposure to glucose and lipids inhibits glucose-induced insulin secretion downstream of granule fusion with plasma membrane Effects of type-selective phosphodiesterase inhibitors on glucose-induced insulin secretion and islet phosphodiesterase activity Impairment of glucose-induced insulin secretion and glucose tolerance during colchicine treatment Inhibition of glucose-induced insulin secretion by intravenous colchicine in man Cyclosporin A stimulation of glucose-induced insulin secretion in MIN6 cells Peroxiredoxin 4 improves insulin biosynthesis and glucose-induced insulin secretion in insulin-secreting INS-1E cells. Propionate inhibits glucose-induced insulin secretion in isolated rat pancreatic islets. Essential role of acetyl-CoA carboxylase in the glucose-induced insulin secretion in a pancreatic beta-cell line The novel imidazoline compound BL11282 potentiates glucose-induced insulin secretion in pancreatic beta-cells in the absence of modulation of K(ATP) channel activity. Role of phospholipase D1 in glucose-induced insulin secretion in pancreatic Beta cells Near normalisation of blood glucose improves the potentiating effect of GLP-1 on glucose-induced insulin secretion in patients with type 2 diabetes Endogenous nitric oxide inhibits glucose-induced insulin secretion by suppression of phosphofructokinase activity in pancreatic islets. Overexpression of lactate dehydrogenase A attenuates glucose-induced insulin secretion in stable MIN-6 beta-cell lines Effects of porcine galanin, galanin(1-15)NH2 and its new analogues on glucose-induced insulin secretion. Inhibitory effect of obestatin on glucose-induced insulin secretion in rats Biotin enhances ATP synthesis in pancreatic islets of the rat, resulting in reinforcement of glucose-induced insulin secretion P2Y purinergic potentiation of glucose-induced insulin secretion and pancreatic beta-cell metabolism PED/PEA-15 regulates glucose-induced insulin secretion by restraining potassium channel expression in pancreatic beta-cells Protein farnesylation-dependent Raf/extracellular signal-related kinase signaling links to cytoskeletal remodeling to facilitate glucose-induced insulin secretion in pancreatic beta-cells. Daily rhythm of glucose-induced insulin secretion by isolated islets from intact and pinealectomized rat. The role of phospholipid-derived mediators including arachidonic acid, its metabolites, and inositoltrisphosphate and of intracellular Ca2+ in glucose-induced insulin secretion by pancreatic islets Suppression of adenylate kinase catalyzed phosphotransfer precedes and is associated with glucose-induced insulin secretion in intact HIT-T15 cells Effect of low temperatures on glucose-induced insulin secretion and ionic fluxes in rat pancreatic islets The calcium/calmodulin-dependent phosphodiesterase PDE1C down-regulates glucose-induced insulin secretion The bile acid TUDCA increases glucose-induced insulin secretion via the cAMP/PKA pathway in pancreatic beta cells Mechanism of glucose-induced insulin secretion Neuronal traits are required for glucose-induced insulin secretion Role of peroxisome proliferator-activated receptor gamma in glucose-induced insulin secretion Administration of sulfonylureas can increase glucose-induced insulin secretion for decades in patients with maturity-onset diabetes of the young. Involvement of phosphatidylinositol-3 kinase/AKT/PKCzeta/lambda pathway in the effect of palmitate on glucose-induced insulin secretion. GIP regulates glucose transporters, hexokinases, and glucose-induced insulin secretion in RIN 1046-38 cells Effects of GLP-1-(7-36)NH2, GLP-1-(7-37), and GLP-1- (9-36)NH2 on intravenous glucose tolerance and glucose-induced insulin secretion in healthy humans Arachidonic acid as a second messenger in glucose-induced insulin secretion from pancreatic beta-cells. Magnesium Modulation of Glucose-Induced Insulin Secretion by the Perfused Rat Pancreas* Is endogenous GLP-1 the only important enhancer of glucose-induced insulin secretion in type 2 diabetes? Phorbol-ester-induced down-regulation of protein kinase C in mouse pancreatic islets. Potentiation of phase 1 and inhibition of phase 2 of glucose-induced insulin secretion Reversible impairment of glucose-induced insulin secretion in SHR/N-cp rats. Genetic model of type II diabetes. Hexamminecobalt(III) chloride inhibits glucose-induced insulin secretion at the exocytotic process Immunocytochemical localization of alpha-protein kinase C in rat pancreatic beta-cells during glucose-induced insulin secretion Overnight culture unmasks glucose-induced insulin secretion in mouse islets lacking ATP-sensitive K+ channels by improving the triggering Ca2+ signal Poor pubertal protein nutrition disturbs glucose-induced insulin secretion process in pancreatic islets and programs rats in adulthood to increase fat accumulation. Beta oxidation in the brain is required for the effects of non-esterified fatty acids on glucose-induced insulin secretion in rats. Feedback modulation of glucose-induced insulin secretion by arachidonic acid metabolites: possible molecular mechanisms and relevance to diabetes mellitus Association of NAD(P)H oxidase with glucose-induced insulin secretion by pancreatic beta-cells. Leucine regulation of glucokinase and ATP synthase sensitizes glucose-induced insulin secretion in pancreatic beta-cells Activation of PPARδ up-regulates the expression of insulin gene transcription factor MafA and ameliorates glucose-induced insulin secretion impaired by palmitate Effect of Pancreatic Adrenergic Tone Modifications Prior to Glucose-Induced Insulin Secretion Immaturity of glucose-induced insulin secretion in fetal rat islets is due to low glucokinase activity Pituitary adenylate cyclase-activating polypeptide (PACAP) is an islet substance serving as an intra-islet amplifier of glucose-induced insulin secretion in rats Effect of low temperatures on glucose-induced insulin secretion and glucose metabolism in isolated pancreatic islets of the rat. Overexpression of protein-tyrosine phosphatase PTP sigma is linked to impaired glucose-induced insulin secretion in hereditary diabetic Goto-Kakizaki rats Antiaging gene Klotho enhances glucose-induced insulin secretion by up-regulating plasma membrane levels of TRPV2 in MIN6 β-cells Impaired glucose-induced insulin secretion: studies in animal models with spontaneous NIDDM. Tyrosine kinases play a permissive role in glucose-induced insulin secretion from adult rat islets. Mitochondria-derived glutamate at the interplay between branched-chain amino acid and glucose-induced insulin secretion Eicosapentaenoic acid (C20:5) augments glucose-induced insulin secretion from beta-TC3 insulinoma cells.

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