About: samarium (153sm) lexidronam

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About: samarium (153sm) lexidronam Goto Sponge NotDistinct Permalink

An Entity of Type : wikibase:Item, within Data Space : wikidata.demo.openlinksw.com associated with source document(s)

pharmaceutical drug

Attributes	Values
rdf:type	Item
description	composto chimico (it) composé chimique (fr) תרכובת (he) chemische Verbindung (de) pharmaceutical drug (en) քիմիական միացություն (hy) chemická sloučenina (cs) chemische verbinding (nl) kemia kombinaĵo (eo) związek chemiczny (pl) component quimic (oc) compost químic (ca) composto químico (gl) composto químico (pt) composto químico (pt-br) compuesto quimico (an) compuestu químicu (ast) compus chimic (ro) kemiallinen yhdiste (fi) kjemisk forbindelse (nb) kjemisk sambinding (nn) konposatu kimiko (eu) مركب كيميائي (ar) کیٖمیٲیی مُرَکَب (ks) রাসায়নিক যৌগ (bn) compuesto químico (es)
rdfs:label	samarium (153sm) lexidronam (en)
skos:prefLabel	samarium (153sm) lexidronam (en)
name	samarium (153sm) lexidronam (en)
isomeric SMILES	wds:Q20817238-DBB99E96-4DB1-4912-B727-C9038C230ABA
isomeric SMILES	C(CN(CP(=O)(O)[O-])CP(=O)(O)[O-])N(CP(=O)(O)O)CP(=O)(O)[O-].[153Sm+3]
subject has role	wds:Q20817238-B207696E-D903-483C-8F7C-01835AB28E85
subject has role	non-opioid analgesic
instance of	wds:Q20817238-292C54E3-9B4B-40A8-BE63-E23EEF346762
instance of	type of chemical entity
subclass of	wds:Q20817238-696846F4-1B9A-4D22-BA55-C872E1E7EDB2
subclass of	chemical substance
has use	wds:Q20817238-7ACD8B1D-1069-4E00-B91E-F687924DF0C8
has use	medication
Probes And Drugs ID	wds:Q20817238-FC55442F-625A-4400-8A11-77DE5C8008CF
CAS Registry Number	wds:Q20817238-E01D568D-646C-45F0-A18F-9D4C36556530
canonical SMILES	wds:Q20817238-7E4B7F38-703F-4181-A4F5-1E0C6526D45B
InChI	wds:Q20817238-47DF5136-F6DE-4C76-A83A-8E88022AE33C
InChIKey	wds:Q20817238-27D1CA6E-DCC1-4F46-BADF-8BEC9F7995F6
chemical formula	wds:Q20817238-1C8C4BE7-50D9-48A2-8527-2BF545CB6C7E
DSSTox substance ID	wds:Q20817238-6CDD0ADC-CC05-4A3C-8461-B13CFD2C7589
RxNorm ID	wds:Q20817238-1AA03B27-E0E3-4A94-B9FB-0503B8C364AB
UNII	wds:Q20817238-3FBF9500-477C-4755-A35C-81835B4F18BB
ChemSpider ID	wds:Q20817238-968BC78C-3674-4711-B3B2-156CD7A806DA
PubChem CID	wds:Q20817238-D48B60AC-7D16-45E9-AABD-1CB2A047F784
DrugBank ID	wds:Q20817238-2C47755F-A48E-4E00-81ED-2E76E91A4E6C
DSSTOX compound identifier	wds:Q20817238-9F4C0429-3FBD-469C-B665-B902DA756847
ChemSpider ID	http://rdf.chemspider.com/143933
PubChem CID	http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID76962714
Probes And Drugs ID	PD059185
CAS Registry Number	122575-21-7
canonical SMILES	C(CN(CP(=O)(O)[O-])CP(=O)(O)[O-])N(CP(=O)(O)O)CP(=O)(O)[O-].[Sm+3]
InChI	InChI=1S/C6H20N2O12P4.Sm/c9-21(10,11)3-7(4-22(12,13)14)1-2-8(5-23(15,16)17)6-24(18,19)20;/h1-6H2,(H2,9,10,11)(H2,12,13,14)(H2,15,16,17)(H2,18,19,20);/q;+3/p-3/i;1+3
InChIKey	JSTADIGKFYFAIY-GJNDDOAHSA-K
chemical formula	C₆H₁₇N₂O₁₂P₄Sm
DSSTox substance ID	DTXSID40894187
RxNorm ID	177906
UNII	745X144DZY
ChemSpider ID	143933
PubChem CID	76962714
DrugBank ID	05273
DSSTOX compound identifier	DTXCID401324231
skos:altLabel	Samarium (153Sm) lexidronam (en) 153SM-EDTMP (en) Samarium (153 Sm) lexidronam (en) Samarium Sm-153 lexidronam (en) Samarium-153 lexidronam (en) Samarium-153-EDTMP (en) samarium sm-153 lexidronam (en)
mass	wds:Q20817238-004766BA-3369-4F37-A808-4FAE49C2C7E6
MeSH descriptor ID	wds:Q20817238-C7A6050D-9592-44E1-B68F-D7A3AFA18421
MeSH descriptor ID	http://id.nlm.nih.gov/mesh/C061972
mass	585.895 (xsd:decimal)
MeSH descriptor ID	C061972
is owl:sameAs of	samarium (153sm) lexidronam
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q20817238
is main subject of	Safety and efficacy of repeat administration of samarium Sm-153 lexidronam to patients with metastatic bone pain Samarium Sm-153 lexidronam for the palliation of bone pain associated with metastases A method for measurement of the uptake patterns of two beta-emitting radionuclides in the same tissue section with a digital silicon detector: application to a study of 89SrCl2 and 153Sm-EDTMP in a dog with spontaneous osteosarcoma Dose response relationship and multiple dose efficacy and toxicity of samarium-153-EDTMP in metastatic cancer to bone Efficacy and safety of repeated samarium-153 lexidronam treatment in a patient with prostate cancer and metastatic bone pain. A comparative study of 188Re-HEDP, 186Re-HEDP, 153Sm-EDTMP and 89Sr in the treatment of painful skeletal metastases Clinical Efficacy and Safety Comparison of 177Lu-EDTMP with 153Sm-EDTMP on an Equidose Basis in Patients with Painful Skeletal Metastases Palliation of pain associated with metastatic bone cancer using samarium-153 lexidronam: a double-blind placebo-controlled clinical trial Samarium-153-EDTMP biodistribution and dosimetry estimation 153Sm-EDTMP for bone pain palliation in skeletal metastases Evaluation of efficacy of 153Sm-EDTMP in patients with painful bone metastases of breast cancer Safety analysis of repeated high doses of samarium-153 lexidronam in men with hormone-naive prostate cancer metastatic to bone Samarium-153-EDTMP in bone metastases of hormone refractory prostate carcinoma: a phase I/II trial Samarium-153-EDTMP: pharmacokinetic, toxicity and pain response using an escalating dose schedule in treatment of metastatic bone cancer Dose-finding study of 153Sm-EDTMP in patients with poor-prognosis osteosarcoma Bone-seeking radiopharmaceuticals as targeted agents of osteosarcoma: samarium-153-EDTMP and radium-223. Samarium lexidronam (153Sm-EDTMP): skeletal radiation for osteoblastic bone metastases and osteosarcoma Phase I study of samarium-153 lexidronam with docetaxel in castration-resistant metastatic prostate cancer

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