About: Protein O-fucosyltransferase 1

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About: Protein O-fucosyltransferase 1 Goto Sponge NotDistinct Permalink

An Entity of Type : wikibase:Item, within Data Space : wikidata.demo.openlinksw.com associated with source document(s)

mammalian protein found in Homo sapiens

Attributes	Values
rdf:type	Item
description	protein (sv) protein (id) protèin (ace) proteinë (sq) mammalian protein found in Homo sapiens (en) білок людини (uk) بروتين في الإنسان العاقل (ar) Protein in Homo sapiens (de) proteïne in Protein O-fucosyltransferase 1 (nl)
rdfs:label	Protein O-fucosyltransferase 1 (en)
skos:prefLabel	Protein O-fucosyltransferase 1 (en)
name	Protein O-fucosyltransferase 1 (en)
instance of	wds:Q15996645-219ACAF8-FE55-4031-A9B0-5FD25E22821F
instance of	protein
found in taxon	wds:Q15996645-9467304F-9FDC-4FE2-A039-D332CA1C34C6
found in taxon	Homo sapiens
molecular function	wds:Q15996645-083667D2-6D3B-481A-B1B6-8F40C3E55D4F wds:Q15996645-1CD7A4B6-E5CB-43A5-800E-FE0779452419 wds:Q15996645-6F1EA813-CB2E-44FA-9463-D931B3693C19 wds:Q15996645-7C90D073-780F-4BD1-AA23-060929C9F291 wds:Q15996645-A39AA2C4-EAE7-4332-A740-6D6D11B43F73
molecular function	transferase activity glycosyltransferase activity fucosyltransferase activity peptide-O-fucosyltransferase activity
cell component	wds:Q15996645-6FFCADAD-A688-4AF3-93A4-CBF1382CD869 wds:Q15996645-CFF033E9-76BB-4F55-9A5E-57896D472726 wds:Q15996645-E148FFCD-DFEB-4286-A7D2-B996B09C1EAC
cell component	endoplasmic reticulum membrane
skos:altLabel	GDP-fucose protein O-fucosyltransferase 1 (en) O-FucT-1 (en) POFUT1 (en) o-fucosyltransferase protein (en) peptide-O-fucosyltransferase 1 (en)
UniProt protein ID	wds:Q15996645-484B4AC7-EF01-42C1-BFA7-6DBF95FE1ED4
RefSeq protein ID	wds:Q15996645-284D8348-E04A-41D5-9AD0-7C78DF507354 wds:Q15996645-74AE54C7-35E6-4F03-B0AF-16BB228B6B49
biological process	wds:Q15996645-050CF78F-2413-4880-9B4E-5AE070EB1C26 wds:Q15996645-1183F860-E852-4B10-ACB4-3587CC450ECB wds:Q15996645-17163426-686C-4D5A-8FA8-E5DCAB89D234 wds:Q15996645-27AE2311-59A3-4956-AAD9-41206152D88D wds:Q15996645-306C08FA-EDEC-4B63-9636-AA813A664237 wds:Q15996645-73D8DD4E-1C58-4F5D-957A-EBD2601A626E wds:Q15996645-888C61A6-3985-48C2-A288-7B393F5D0965 wds:Q15996645-91619187-6A21-4F85-9554-15CC62D71401 wds:Q15996645-93C8D1D1-1E56-46EF-B0B4-8F26E3A8A8D2 wds:Q15996645-C4BA64BE-16B9-4CE1-BECA-22923B073A1C wds:Q15996645-D323BD6F-C7FC-4B62-9D0B-744B91BC728B wds:Q15996645-D39196AC-3CC7-49D1-BF38-B69DDCECB03F wds:Q15996645-D42BCDAB-6037-4EA3-AADB-F77CA4C75384 wds:Q15996645-E2071A79-A194-471E-A94A-D77C1BEEDCF9
encoded by	wds:Q15996645-7D4A56A2-47FD-4C10-BF9C-7EDBFFC59235
Ensembl protein ID	wds:Q15996645-ADCD3681-FD08-421B-92FB-461AA7BD8469 wds:Q15996645-F4AD7E4A-522B-4822-983B-F69D1FBD611B
UniProt protein ID	uniprot:uniprot/Q9H488
RefSeq protein ID	uniprot:refseq/NP_056167 uniprot:refseq/NP_758436
UniProt protein ID	Q9H488
RefSeq protein ID	NP_056167 NP_758436
biological process	somitogenesis Notch signaling pathway angiogenesis nervous system development heart development carbohydrate metabolic process regulation of Notch signaling pathway protein glycosylation regulation of transcription, DNA-templated fucose metabolic process protein O-linked glycosylation embryo development O-glycan processing protein O-linked fucosylation
encoded by	POFUT1
Ensembl protein ID	ENSP00000364882 ENSP00000364902
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q15996645
is has part(s) of	Fucosylation of Pre-NOTCH by POFUT1
is main subject of	Composition of Drosophila melanogaster proteome involved in fucosylated glycan metabolism Modification of epidermal growth factor-like repeats with O-fucose. Molecular cloning and expression of a novel GDP-fucose protein O-fucosyltransferase O-fucosylation of notch occurs in the endoplasmic reticulum Identification of a GDP-L-fucose:polypeptide fucosyltransferase and enzymatic addition of O-linked fucose to EGF domains Structure of human POFUT1, its requirement in ligand-independent oncogenic Notch signaling, and functional effects of Dowling-Degos mutations
is has part(s) of	wds:Q50298607-97319877-1B22-48CD-B62D-C75E3734C2C9
is main subject of	wds:Q30090224-25504296-5C8F-44EB-B631-69F183B55B8D wds:Q24291613-50EE8510-FE5B-4F37-AC21-64330BEB0A7A wds:Q24338227-66638231-F7EB-4DF4-AD62-EF947F91D348 wds:Q24291882-381D0AE6-A586-421A-8D02-210C8F540B46 wds:Q24318707-B47BE20A-BA33-4B06-9284-97027F15ED60
is encodes of	POFUT1
is encodes of	wds:Q18037225-5E34E7B1-1BE8-4D4E-B76C-E3F96EF7A528

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