About: sequence-specific DNA binding

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About: sequence-specific DNA binding Goto Sponge NotDistinct Permalink

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Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.

Attributes	Values
rdf:type	Item
description	moleculaire functie (nl) selektivna in nekovalentna interakcija z DNA s specifično nukleotidno sestavo (sl) Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding. (en)
exact match	wds:Q14818107-06E0F9CE-7DAE-4BF3-9A49-87703EB477C9
exact match	http://purl.obolibrary.org/obo/GO_0043565
rdfs:label	sekvensspesifikk DNA-binding (nn) sekvenčno specifična vezava DNA (sl) sequence-specific DNA binding (en) sequentie-specifieke DNA-binding (nl)
skos:prefLabel	sekvensspesifikk DNA-binding (nn) sekvenčno specifična vezava DNA (sl) sequence-specific DNA binding (en) sequentie-specifieke DNA-binding (nl)
name	sekvensspesifikk DNA-binding (nn) sekvenčno specifična vezava DNA (sl) sequence-specific DNA binding (en) sequentie-specifieke DNA-binding (nl)
Gene Ontology ID	wds:Q14818107-946CFD96-1EA3-4B89-8D82-5A5E91D126C3
Gene Ontology ID	GO:0043565
instance of	wds:Q14818107-0735DD5D-F195-46F7-BD19-11A305138C6C
instance of	molecular function
subclass of	wds:Q14818107-9C5CE75E-4849-4331-A511-C05F4CCF51B6
subclass of	DNA binding
skos:altLabel	GO:0043565 (en) GO:0043565 (nn) sekvenčno specifična vezava DNK (sl) sequence specific DNA binding (en) vezava DNA glede na zaporedje (sl) vezava DNK glede na zaporedje (sl)
UMLS CUI	wds:Q14818107-439F632D-9588-4F6C-AD0F-F91C179759B2
UMLS CUI	C1624609
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q14818107
is subclass of of	telomeric DNA binding sequence-specific single stranded DNA binding methyl-CpG binding sequence-specific double-stranded DNA binding unmethylated CpG binding
is subclass of of	wds:Q22314931-A0E67891-2C64-4401-A4E4-8572E6D31C26 wds:Q15315116-05F34303-FD78-480F-BB47-FCCDA95C9611 wds:Q22315094-989C72D3-F431-4A5E-9882-DB69E01D4D04 wds:Q14908000-6DF0C296-3D99-48B3-B1C8-2B59965D68FB wds:Q14905544-5CC499F8-AA99-4C6F-9790-5C309D4940FC
is main subject of	Differential mechanisms of LEF/TCF family-dependent transcriptional activation by beta-catenin and plakoglobin Cloning of a cellular factor, interleukin binding factor, that binds to NFAT-like motifs in the human immunodeficiency virus long terminal repeat Solution structure of the DNA-binding domain of interleukin enhancer binding factor 1 (FOXK1a) Crystal structure of the human FOXK1a-DNA complex and its implications on the diverse binding specificity of winged helix/forkhead proteins Cloning and characterization of seven human forkhead proteins: binding site specificity and DNA bending Characterization and chromosomal mapping of the gene encoding the cellular DNA binding protein ILF Sequence-specific recognition of methylated DNA by human zinc-finger proteins The conserved Cockayne syndrome B-piggyBac fusion protein (CSB-PGBD3) affects DNA repair and induces both interferon-like and innate antiviral responses in CSB-null cells. Mutations in NEUROD1 are associated with the development of type 2 diabetes mellitus Increased expression of the FIGLA transcription factor is associated with primordial follicle formation in the human fetal ovary Mutations in the THAP1 gene are responsible for DYT6 primary torsion dystonia Bcl2 regulation by the melanocyte master regulator Mitf modulates lineage survival and melanoma cell viability Functions of the POU domain genes Skn-1a/i and Tst-1/Oct-6/SCIP in epidermal differentiation Transcription factor AP-4 contains multiple dimerization domains that regulate dimer specificity Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1 Human Slug is a repressor that localizes to sites of active transcription Isolation and identification of homeobox genes from the human placenta including a novel member of the Distal-less family, DLX4 A beta-catenin/XTcf-3 complex binds to the siamois promoter to regulate dorsal axis specification in Xenopus DNA-binding specificities of human transcription factors Uncoupling FoxO3A mitochondrial and nuclear functions in cancer cells undergoing metabolic stress and chemotherapy. Identification of a photoreceptor cell-specific nuclear receptor DNA binding activity of the fetal Alz-50 clone 1 (FAC1) protein is enhanced by phosphorylation Fetal Alz-50 clone 1, a novel zinc finger protein, binds a specific DNA sequence and acts as a transcriptional regulator Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension The THAP domain of THAP1 is a large C2CH module with zinc-dependent sequence-specific DNA-binding activity Structure-function analysis of the THAP zinc finger of THAP1, a large C2CH DNA-binding module linked to Rb/E2F pathways The THAP-zinc finger protein THAP1 regulates endothelial cell proliferation through modulation of pRB/E2F cell-cycle target genes A novel FOXE1 mutation (R73S) in Bamforth-Lazarus syndrome causing increased thyroidal gene expression MSX1 and TGF-beta3 are novel target genes functionally regulated by FOXE1 Peroxisome proliferator-activated receptor γ coactivator 1 (PGC-1)- and estrogen-related receptor (ERR)-induced regulator in muscle 1 (Perm1) is a tissue-specific regulator of oxidative capacity in skeletal muscle cells Transcriptional repression mediated by the PR domain zinc finger gene RIZ Critical DNA binding interactions of the insulator protein CTCF: a small number of zinc fingers mediate strong binding, and a single finger-DNA interaction controls binding at imprinted loci Biochemical characterization of the mammalian Cux2 protein RP58 associates with condensed chromatin and mediates a sequence-specific transcriptional repression Foxe3 haploinsufficiency in mice: a model for Peters' anomaly The octamer motif present in the Rex-1 promoter binds Oct-1 and Oct-3 expressed by EC cells and ES cells The adenovirus major late transcription factor USF is a member of the helix-loop-helix group of regulatory proteins and binds to DNA as a dimer Characterization of the zinc finger protein encoded by the WT1 Wilms' tumor locus PPARgamma promotes monocyte/macrophage differentiation and uptake of oxidized LDL Identification of a novel mutation disrupting the DNA binding activity of GCM2 in autosomal recessive familial isolated hypoparathyroidism Identification and characterization of novel parathyroid-specific transcription factor Glial Cells Missing Homolog B (GCMB) mutations in eight families with autosomal recessive hypoparathyroidism. Characterization of a subset of the basic-helix-loop-helix-PAS superfamily that interacts with components of the dioxin signaling pathway Cloning of novel isoforms of the human Gli2 oncogene and their activities to enhance tax-dependent transcription of the human T-cell leukemia virus type 1 genome p62/SQSTM1 is a target gene for transcription factor NRF2 and creates a positive feedback loop by inducing antioxidant response element-driven gene transcription Characterization of a dimerization motif in AP-2 and its function in heterologous DNA-binding proteins Interaction of hepatitis C virus core protein with retinoid X receptor alpha modulates its transcriptional activity Definition of a novel growth factor-dependent signal cascade for the suppression of bile acid biosynthesis THAP proteins target specific DNA sites through bipartite recognition of adjacent major and minor grooves Characterization of mutations in the FOXE1 gene in a cohort of unrelated Malaysian patients with congenital hypothyroidism and thyroid dysgenesis Crystal structure of the human LRH-1 DBD-DNA complex reveals Ftz-F1 domain positioning is required for receptor activity Monomeric complex of human orphan estrogen related receptor-2 with DNA: a pseudo-dimer interface mediates extended half-site recognition Regulation of EphA8 gene expression by TALE homeobox transcription factors during development of the mesencephalon Structural and functional insights into the human Börjeson-Forssman-Lehmann syndrome-associated protein PHF6. The nuclear orphan receptors COUP-TFII and Ear-2 act as silencers of the human oxytocin gene promoter ZNF274 recruits the histone methyltransferase SETDB1 to the 3' ends of ZNF genes A recurrent p.Arg92Trp variant in steroidogenic factor-1 (NR5A1) can act as a molecular switch in human sex development Pleiomorphic adenoma gene-like-2, a zinc finger protein, transactivates the surfactant protein-C promoter

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