About: Atsushi Ohtsu

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Japanese medical researcher

Attributes	Values
rdf:type	Item
description	日本の医学者 (ja) Japanese medical researcher (en)
rdfs:label	Atsushi Ohtsu (en) Atsushi Ohtsu (tr) Atsushi Ohtsu (ast) 大津敦 (ja)
skos:prefLabel	Atsushi Ohtsu (en) Atsushi Ohtsu (tr) Atsushi Ohtsu (ast) 大津敦 (ja)
name	Atsushi Ohtsu (en) Atsushi Ohtsu (tr) Atsushi Ohtsu (ast) 大津敦 (ja)
instance of	wds:Q115365827-1E453812-EC68-4333-93C9-19F8EB31AD6C
instance of	Homo sapiens
skos:altLabel	Atsushi Ōtsu (en)
occupation	wds:Q115365827-47FF8E8A-36F8-443C-B001-F818FA4B8DE8
employer	wds:Q115365827-3CFF20E2-A1F8-4EBE-8DB1-441A86E08AFA
country of citizenship	wds:Q115365827-A69EED2C-0B64-4BA3-915B-EC2EE304A056
occupation	researcher
employer	National Cancer Center Hospital East
country of citizenship	Japan
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q115365827
is author of	Long-term toxicity after definitive chemoradiotherapy for squamous cell carcinoma of the thoracic esophagus Magnifying narrow-band imaging versus magnifying white-light imaging for the differential diagnosis of gastric small depressive lesions: a prospective study Enhanced antitumor effect of anti-tissue factor antibody-conjugated epirubicin-incorporating micelles in xenograft models. Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastric or gastro-oesophageal junction cancer (ToGA): a phase 3, open-label, randomised controlled trial Photodynamic therapy as salvage treatment for local failures after definitive chemoradiotherapy for esophageal cancer Nonrandomized comparison between definitive chemoradiotherapy and radical surgery in patients with T(2-3)N(any) M(0) squamous cell carcinoma of the esophagus EMR as salvage treatment for patients with locoregional failure of definitive chemoradiotherapy for esophageal cancer Ramucirumab plus paclitaxel versus placebo plus paclitaxel in patients with previously treated advanced gastric or gastro-oesophageal junction adenocarcinoma (RAINBOW): a double-blind, randomised phase 3 trial Phase II study of sequential methotrexate and 5-fluorouracil chemotherapy against peritoneally disseminated gastric cancer with malignant ascites: a report from the Gastrointestinal Oncology Study Group of the Japan Clinical Oncology Group, JCOG 960 Randomized Phase III study of 5-fluorouracil continuous infusion vs. sequential methotrexate and 5-fluorouracil therapy in far advanced gastric cancer with peritoneal metastasis (JCOG0106). Everolimus for previously treated advanced gastric cancer: results of the randomized, double-blind, phase III GRANITE-1 study. Phase I clinical and pharmacokinetic study of RAD001 (everolimus) administered daily to Japanese patients with advanced solid tumors Nonplatinum-based chemotherapy with irinotecan plus docetaxel for advanced or metastatic olfactory neuroblastoma: a retrospective analysis of 12 cases. Phase II study of biweekly irinotecan and mitomycin C combination therapy in patients with fluoropyrimidine-resistant advanced colorectal cancer Lapatinib plus paclitaxel versus paclitaxel alone in the second-line treatment of HER2-amplified advanced gastric cancer in Asian populations: TyTAN--a randomized, phase III study Comparison of HER2 gene amplification assessed by fluorescence in situ hybridization and HER2 protein expression assessed by immunohistochemistry in gastric cancer. Current status and future prospects of chemotherapy for metastatic gastric cancer: a review Irinotecan pharmacokinetics/pharmacodynamics and UGT1A genetic polymorphisms in Japanese: roles of UGT1A16 and 28 UGT1A1 haplotypes associated with reduced glucuronidation and increased serum bilirubin in irinotecan-administered Japanese patients with cancer Phase I/II study of sunitinib malate in Japanese patients with gastrointestinal stromal tumor after failure of prior treatment with imatinib mesylate Functional analysis of four naturally occurring variants of human constitutive androstane receptor Multicenter phase II study of everolimus in patients with previously treated metastatic gastric cancer Bevacizumab in combination with chemotherapy as first-line therapy in advanced gastric cancer: a randomized, double-blind, placebo-controlled phase III study Long-term outcome of transoral organ-preserving pharyngeal endoscopic resection for superficial pharyngeal cancer. Gastric Cancer Working Group report Genetic variations and haplotypes of ABCC2 encoding MRP2 in a Japanese population Squamous cell carcinoma in situ at oropharyngeal and hypopharyngeal mucosal sites. mTOR as a therapeutic target in patients with gastric cancer Fourteen novel genetic variations and haplotype structures of the TYMS gene encoding human thymidylate synthase (TS) Prognostic impact of HER2, EGFR, and c-MET status on overall survival of advanced gastric cancer patients Local recurrence of squamous-cell carcinoma of the esophagus after EMR Safety and Pharmacokinetics of Second-line Ramucirumab plus FOLFIRI in Japanese Patients with Metastatic Colorectal Carcinoma Phase 1 pharmacokinetic study of the oral pan-AKT inhibitor MK-2206 in Japanese patients with advanced solid tumors Association between aldehyde dehydrogenase gene polymorphisms and the phenomenon of field cancerization in patients with head and neck cancer Risk of multiple squamous cell carcinomas both in the esophagus and the head and neck region A new technique for endoscopic mucosal resection with an insulated-tip electrosurgical knife improves the completeness of resection of intramucosal gastric neoplasms Disparities in gastric cancer chemotherapy between the East and West Phase I study of NK012, a novel SN-38-incorporating micellar nanoparticle, in adult patients with solid tumors Epstein-Barr virus involvement is a predictive factor for the resistance to chemoradiotherapy of gastric diffuse large B-cell lymphoma Phase I dose-escalation study of buparlisib (BKM120), an oral pan-class I PI3K inhibitor, in Japanese patients with advanced solid tumors Adjuvant therapy with imatinib mesylate after resection of primary high-risk gastrointestinal stromal tumors in Japanese patients Haplotypes of CYP3A4 and their close linkage with CYP3A5 haplotypes in a Japanese population. Bevacizumab in combination with chemotherapy as first-line therapy in advanced gastric cancer: a biomarker evaluation from the AVAGAST randomized phase III trial Phase II study of oxaliplatin in japanese patients with metastatic colorectal cancer refractory to fluoropyrimidines Phase II study of oral S-1 for treatment of metastatic colorectal carcinoma Clinical impact of criteria for complete response (CR) of primary site to treatment of esophageal cancer Association of multiple Lugol-voiding lesions with synchronous and metachronous esophageal squamous cell carcinoma in patients with head and neck cancer Randomized trial of TAS-102 for refractory metastatic colorectal cancer TAS-102 monotherapy for pretreated metastatic colorectal cancer: a double-blind, randomised, placebo-controlled phase 2 trial Application of a combination of a knowledge-based algorithm and 2-stage screening to hypothesis-free genomic data on irinotecan-treated patients for identification of a candidate single nucleotide polymorphism related to an adverse effect Identification of a candidate single-nucleotide polymorphism related to chemotherapeutic response through a combination of knowledge-based algorithm and hypothesis-free genomic data. Haplotype analysis of ABCB1/MDR1 blocks in a Japanese population reveals genotype-dependent renal clearance of irinotecan Additive effects of drug transporter genetic polymorphisms on irinotecan pharmacokinetics/pharmacodynamics in Japanese cancer patients Impact of CYP3A4 haplotypes on irinotecan pharmacokinetics in Japanese cancer patients. Evaluation of safety, pharmacokinetics, and efficacy of vorinostat, a histone deacetylase inhibitor, in the treatment of gastrointestinal (GI) cancer in a phase I clinical trial Trastuzumab emtansine versus taxane use for previously treated HER2-positive locally advanced or metastatic gastric or gastro-oesophageal junction adenocarcinoma (GATSBY): an international randomised, open-label, adaptive, phase 2/3 study Chemotherapy for metastatic gastric cancer: past, present, and future Pulmonary tumor thrombotic microangiopathy associated with esophageal squamous cell carcinoma Randomized phase III trial of fluorouracil alone versus fluorouracil plus cisplatin versus uracil and tegafur plus mitomycin in patients with unresectable, advanced gastric cancer: The Japan Clinical Oncology Group Study (JCOG9205). Fluorouracil versus combination of irinotecan plus cisplatin versus S-1 in metastatic gastric cancer: a randomised phase 3 study Long-term survival and prognostic factors in patients with metastatic gastric cancers treated with chemotherapy in the Japan Clinical Oncology Group (JCOG) study Chemoradiotherapy for esophageal cancer: current status and perspectives The IDEA (International Duration Evaluation of Adjuvant Chemotherapy) Collaboration: Prospective Combined Analysis of Phase III Trials Investigating Duration of Adjuvant Therapy with the FOLFOX (FOLFOX4 or Modified FOLFOX6) or XELOX (3 versus 6 [...] Close association of UGT1A9 IVS1+399C>T with UGT1A128, 6, or *60 haplotype and its apparent influence on 7-ethyl-10-hydroxycamptothecin (SN-38) glucuronidation in Japanese Functional Characterization of Human UDP-Glucuronosyltransferase 1A9 Variant, D256N, Found in Japanese Cancer Patients Artificially induced epithelial-mesenchymal transition in surgical subjects: its implications in clinical and basic cancer research Expression profiling of esophageal squamous cell carcinoma patients treated with definitive chemoradiotherapy: clinical implications Japanese multicenter phase II study of CHOP followed by radiotherapy in stage I-II, diffuse large B-cell lymphoma of the stomach Phase II study of chemoradiotherapy with 5-fluorouracil and cisplatin for Stage II-III esophageal squamous cell carcinoma: JCOG trial (JCOG 9906). Phase I trial of chemoradiotherapy with the combination of S-1 plus cisplatin for patients with unresectable locally advanced squamous cell carcinoma of the head and neck Genetic variations and haplotype structures of the DPYD gene encoding dihydropyrimidine dehydrogenase in Japanese and their ethnic differences Initial safety report on the tolerability of modified FOLFOX6 as adjuvant therapy in patients with curatively resected stage II or III colon cancer (JFMC41-1001-C2: JOIN trial) A retrospective observational study of clinicopathological features of KRAS, NRAS, BRAF and PIK3CA mutations in Japanese patients with metastatic colorectal cancer Phase 2 study of nilotinib as third-line therapy for patients with gastrointestinal stromal tumor. A multicenter phase II study of TAS-102 monotherapy in patients with pre-treated advanced gastric cancer (EPOC1201).

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