About: Cholesterol 25-Hydroxylase inhibits SARS-CoV-2 and coronaviruses by depleting membrane cholesterol

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About: Cholesterol 25-Hydroxylase inhibits SARS-CoV-2 and coronaviruses by depleting membrane cholesterol Goto Sponge NotDistinct Permalink

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scientific article published on 18 September 2020

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rdf:type	Item
description	wetenschappelijk artikel (nl) artículu científicu espublizáu en setiembre de 2020 (ast) scientific article published on 18 September 2020 (en) наукова стаття, опублікована 18 вересня 2020 (uk)
publication date	wds:Q99566670-7901D091-92BD-4717-87F9-D915F4E6BDF3
publication date	2020-09-18 00:00:00Z (xsd:dateTime)
cites work	wds:Q99566670-04DC6A6E-5722-412C-921F-E68E429A7212 wds:Q99566670-0ADD7F56-938B-4C3B-AB35-324B071E2FB4 wds:Q99566670-0DF7642F-B93F-4B4A-9907-269CB0A4B44E wds:Q99566670-10BB4416-0101-4CBD-A5B6-B99398DC4DA1 wds:Q99566670-17DC12FB-72F0-4BEC-BE13-A4B849FBC5F6 wds:Q99566670-18B5031B-C12F-4AA1-8957-380DBA39CDF2 wds:Q99566670-334BF228-1B9A-487E-9865-41008D6C736F wds:Q99566670-3359F0DF-BD61-4AF5-B8DB-E59D16EF37BE wds:Q99566670-34DA7DC0-C920-4037-95FD-CFA744860687 wds:Q99566670-4105D187-2879-451B-A486-F5A35881F9F6 wds:Q99566670-46F1C6C3-F402-4B5A-8050-AB9EF0F13BB0 wds:Q99566670-49604787-C40B-4AA3-AC1B-9355E6651AE7 wds:Q99566670-4E0DDBA5-1EBB-4973-AD95-C97451D271E8 wds:Q99566670-4FC15488-671D-49CB-BD40-38DA5649582F wds:Q99566670-50DDCDBC-EF4C-4076-9E95-2D04CB2CCABF wds:Q99566670-626F5F3D-4CCB-435C-8D84-86249C297719 wds:Q99566670-6884E7A8-8F0B-4366-B275-9C55012F45B0 wds:Q99566670-69B039AC-0E3D-4CBA-ACB0-D33B69287C16 wds:Q99566670-70C91144-8BDB-4856-913E-84E999F69602 wds:Q99566670-7AD55608-DD4C-4C58-A6AB-BC345B3F22A6 wds:Q99566670-8BE96107-A2CC-4EDC-BB87-A8DFB06DC491 wds:Q99566670-988632CE-F8F3-4710-BE2A-5BA140A92A73 wds:Q99566670-9E1E8DC1-826D-4B2C-89E5-AF46E15F9A99 wds:Q99566670-B03E17C0-EA71-4CBE-B9C8-04A304AE670A wds:Q99566670-B7DE204D-3169-434F-83E8-FF1B71CE091E wds:Q99566670-BC9BD1D9-0B50-451F-9C3B-C5AE13C02B6D wds:Q99566670-C8359A15-FFF1-494F-90BA-86D86BEFF4A8 wds:Q99566670-C87BC5D5-412D-445E-87CB-B30099760A33 wds:Q99566670-CC0235E6-9650-45D2-BD12-90CBE91681D4 wds:Q99566670-D4D8A2A2-BE43-4106-BC14-FC26691C0C47 wds:Q99566670-D640B828-C511-4716-A05F-6C56F5F9F033 wds:Q99566670-D66726C1-0A1E-436C-8E2B-C6E2E23D2909 wds:Q99566670-EF214E56-6A1D-455C-B60E-F2C3A28A02A2 wds:Q99566670-F24D57BA-7BA8-438C-A81E-8311E76CB01C wds:Q99566670-F86ABCCB-E12D-4AF0-A9E2-347FEE04BFA2
cites work	cDNA cloning of mouse and human cholesterol 25-hydroxylases, polytopic membrane proteins that synthesize a potent oxysterol regulator of lipid metabolism Sterols and oxysterols in immune cell function Tissue specific up regulation of ACE2 in rabbit model of atherosclerosis by atorvastatin: role of epigenetic histone modifications. Three pools of plasma membrane cholesterol and their relation to cholesterol homeostasis Interferon-inducible cholesterol-25-hydroxylase broadly inhibits viral entry by production of 25-hydroxycholesterol Interferon-stimulated genes: a complex web of host defenses Activation of the SARS coronavirus spike protein via sequential proteolytic cleavage at two distinct sites Virus entry, assembly, budding, and membrane rafts Vesicular stomatitis virus pseudotyped with severe acute respiratory syndrome coronavirus spike protein The interferons and their receptors--distribution and regulation HIV gp41-mediated membrane fusion occurs at edges of cholesterol-rich lipid domains Effects of 25-hydroxycholesterol on cholesterol esterification and sterol regulatory element-binding protein processing are dissociable: implications for cholesterol movement to the regulatory pool in the endoplasmic reticulum Generation of VSV pseudotypes using recombinant ΔG-VSV for studies on virus entry, identification of entry inhibitors, and immune responses to vaccines Switch-like responses of two cholesterol sensors do not require protein oligomerization in membranes. The role of cholesterol in membrane fusion 25-Hydroxycholesterol Protects Host against Zika Virus Infection and Its Associated Microcephaly in a Mouse Model Origin and evolution of pathogenic coronaviruses The Role of Host Cholesterol During Flavivirus Infection SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor Single-cell landscape of bronchoalveolar immune cells in patients with COVID-19 Super-resolution fluorescence-assisted diffraction computational tomography reveals the three-dimensional landscape of the cellular organelle interactome Monitoring and Modulating Intracellular Cholesterol Trafficking Using ALOD4, a Cholesterol-Binding Protein Oxysterols provide innate immunity to bacterial infection by mobilizing cell surface accessible cholesterol Type I and Type III Interferons - Induction, Signaling, Evasion, and Application to Combat COVID-19 A Multibasic Cleavage Site in the Spike Protein of SARS-CoV-2 Is Essential for Infection of Human Lung Cells TMPRSS2 and TMPRSS4 promote SARS-CoV-2 infection of human small intestinal enterocytes The effect of fluvastatin on cardiac fibrosis and angiotensin-converting enzyme-2 expression in glucose-controlled diabetic rat hearts. Imbalanced Host Response to SARS-CoV-2 Drives Development of COVID-19 COVID-19: Epidemiology, Evolution, and Cross-Disciplinary Perspectives Statin therapy in COVID-19 infection Antiviral activities of type I interferons to SARS-CoV-2 infection Considerations for statin therapy in patients with COVID-19 In-Hospital Use of Statins Is Associated with a Reduced Risk of Mortality among Individuals with COVID-19 Reversal of Surfactant Protein B Deficiency in Patient Specific Human Induced Pluripotent Stem Cell Derived Lung Organoids by Gene Therapy Generation of lung organoids from human pluripotent stem cells in vitro
author name string	wds:Q99566670-052A2D6C-2660-4F99-BD02-8CC38CC1C76C wds:Q99566670-0D8BF83F-8101-4559-AADF-E938FFDCDCD4 wds:Q99566670-36CAE0A7-7FF6-400F-980E-62679CDA246C wds:Q99566670-4A22DE0D-98CA-4D05-AEC6-51FF78A6C62C wds:Q99566670-55735F86-4300-4C32-AB98-8F3E48E7A98C wds:Q99566670-563CC4E0-354B-4768-9DF5-ED506E1FA33B wds:Q99566670-BDD16943-8729-42F8-873A-F5E981E6E330 wds:Q99566670-DC46BD07-4716-4313-84FA-78AF261927DB wds:Q99566670-F042B332-D74D-4C18-B43E-506B24338669 wds:Q99566670-F871D083-A4AE-4C2A-A14A-5051054386EE
author name string	Davey Smith Qiong Zhang Tariq M Rana Shashi Kant Tiwari Aaron F Carlin Shaobo Wang Hui Hui Wanyu Li Ben A Croker Stephen Rawlings
rdfs:label	Cholesterol 25-Hydroxylase inhibits SARS-CoV-2 and coronaviruses by depleting membrane cholesterol (en) Cholesterol 25-Hydroxylase inhibits SARS-CoV-2 and coronaviruses by depleting membrane cholesterol (nl)
skos:prefLabel	Cholesterol 25-Hydroxylase inhibits SARS-CoV-2 and coronaviruses by depleting membrane cholesterol (en)

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