About: A combination of clioquinol, zinc and copper increases the abundance and function of breast cancer resistance protein in human brain microvascular endothelial cells

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About: A combination of clioquinol, zinc and copper increases the abundance and function of breast cancer resistance protein in human brain microvascular endothelial cells Goto Sponge NotDistinct Permalink

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scientific article published on 24 April 2020

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rdf:type	Item
description	wetenschappelijk artikel (nl) artículu científicu espublizáu n'abril de 2020 (ast) наукова стаття, опублікована 24 квітня 2020 (uk) scientific article published on 24 April 2020 (en)
publication date	wds:Q93257503-97E06608-2551-45F1-97F4-34FE257B62CB
publication date	2020-04-24 00:00:00Z (xsd:dateTime)
cites work	wds:Q93257503-11941C96-B33A-4F58-A0BE-C78B43FC3505 wds:Q93257503-13273510-6C46-47B4-84DC-D6C1421CAD9D wds:Q93257503-13F0F9DC-51F0-45C7-950E-C5FFBA4DF0C8 wds:Q93257503-1E9DAF6A-51CD-49BF-91EF-C03260B0CE97 wds:Q93257503-228474F0-CE7B-4994-B625-73453393FA17 wds:Q93257503-327A6A5C-CF9C-415D-AA90-DCEB68F3DA81 wds:Q93257503-3BF46049-5C9B-49B3-9B56-758801F3C343 wds:Q93257503-44DC81AE-5700-423B-A699-B76BD74B04AE wds:Q93257503-4BF06DD5-AFD1-4CCF-B5EB-BCC5DDAE39E0 wds:Q93257503-4CD23EF1-48F0-4A00-B781-EADDED2F3F82 wds:Q93257503-5243673B-7FF8-4673-8FD8-3BD90097AB14 wds:Q93257503-53B39559-3CC5-4EDF-819E-2D53FEE1C2A8 wds:Q93257503-53CFB924-273D-4EA0-8677-7C7DA272F5A5 wds:Q93257503-571C0B3E-1967-4173-926C-0F6BA9129536 wds:Q93257503-5BDB2D4C-6ACB-4424-9E92-B4C6953DF83A wds:Q93257503-5D931870-1886-4BA3-A152-970F88F5ACC3 wds:Q93257503-5F5E4A31-5BFD-4264-A91F-CE090DA238FD wds:Q93257503-6AFE5D40-51D4-4BAB-97F1-9F7035102AF2 wds:Q93257503-788F5DDF-8DC1-4673-B216-3664F1F66A82 wds:Q93257503-8F241EB7-55A5-4DA0-8C15-A055BCAB3E2C wds:Q93257503-97129158-057A-4266-9CE2-149345DFE1AA wds:Q93257503-9F81371D-4A51-4A20-BED1-881F5BDE4831 wds:Q93257503-A001FB58-9685-48E6-A7E0-A4D15BDE5EFB wds:Q93257503-ADC42487-B01C-4EF7-8A39-356A07BCE2D1 wds:Q93257503-B0B212BF-1F42-497C-AA1C-5F150A4D933B wds:Q93257503-B3D7430C-B418-4752-9461-A906C5F544E5 wds:Q93257503-B49359CD-6AD3-4617-AAD6-02CFB26305EF wds:Q93257503-C07568E8-1CEA-4388-8D6F-EBD70E17F75A wds:Q93257503-C1707A90-5125-4BD4-ABB9-08DE45C0193A wds:Q93257503-C44F3990-5A18-4FC0-81A3-73406A72161A wds:Q93257503-C9BC002D-AB2E-4882-BEF3-4DAEBCDF2FEC wds:Q93257503-CED62955-1B4D-4974-AD7E-00570C3265C6 wds:Q93257503-E3415F91-0192-460F-88CE-5BE6B8D4CD9B wds:Q93257503-E6331725-0D37-40F9-9316-902694E11411 wds:Q93257503-ECDA9AB4-00EF-4A12-9739-F7460CD1D4E6 wds:Q93257503-FD6E99D4-49B2-42C2-8F7B-43EA48085C58 wds:Q93257503-FF189617-5835-4EA0-AC8C-42A888A03AFC
cites work	Clioquinol and pyrrolidine dithiocarbamate complex with copper to form proteasome inhibitors and apoptosis inducers in human breast cancer cells Structure and function of the blood-brain barrier Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method ABCG2 is upregulated in Alzheimer's brain with cerebral amyloid angiopathy and may act as a gatekeeper at the blood-brain barrier for Abeta(1-40) peptides. ABCG2 reduces ROS-mediated toxicity and inflammation: a potential role in Alzheimer's disease. Treatment with a copper-zinc chelator markedly and rapidly inhibits beta-amyloid accumulation in Alzheimer's disease transgenic mice. Evaluating strategies to normalise biological replicates of Western blot data Inhibition of glycogen synthase kinase-3beta by bivalent zinc ions: insight into the insulin-mimetic action of zinc P-glycoprotein deficiency at the blood-brain barrier increases amyloid-beta deposition in an Alzheimer disease mouse model Influence of breast cancer resistance protein (Abcg2) and p-glycoprotein (Abcb1a) on the transport of imatinib mesylate (Gleevec® ) across the mouse blood-brain barrier The effect of Bcrp1 (Abcg2) on the in vivo pharmacokinetics and brain penetration of imatinib mesylate (Gleevec): implications for the use of breast cancer resistance protein and P-glycoprotein inhibitors to enable the brain penetration of imatinib Localisation of breast cancer resistance protein in microvessel endothelium of human brain Intramolecular disulfide bond is a critical check point determining degradative fates of ATP-binding cassette (ABC) transporter ABCG2 protein Zinc supplementation reverses alcohol-induced steatosis in mice through reactivating hepatocyte nuclear factor-4alpha and peroxisome proliferator-activated receptor-alpha Constitutive androstane receptor-mediated up-regulation of ATP-driven xenobiotic efflux transporters at the blood-brain barrier Aryl hydrocarbon receptor-mediated up-regulation of ATP-driven xenobiotic efflux transporters at the blood-brain barrier 17-β-Estradiol: a powerful modulator of blood-brain barrier BCRP activity Tumor cellular proteasome inhibition and growth suppression by 8-hydroxyquinoline and clioquinol requires their capabilities to bind copper and transport copper into cells Increasing Cu bioavailability inhibits Abeta oligomers and tau phosphorylation Dexamethasone increases expression and activity of multidrug resistance transporters at the rat blood-brain barrier Regulation of breast cancer resistant protein by peroxisome proliferator-activated receptor α in human brain microvessel endothelial cells Dominant-negative inhibition of breast cancer resistance protein as drug efflux pump through the inhibition of S-S dependent homodimerization Functional characterization of coding polymorphisms in the human MDR1 gene using a vaccinia virus expression system. Clioquinol inhibits the proteasome and displays preclinical activity in leukemia and myeloma BCRP at the blood-brain barrier: genomic regulation by 17β-estradiol. Zinc deficiency induces vascular pro-inflammatory parameters associated with NF-kappaB and PPAR signaling P-glycoprotein and breast cancer resistance protein restrict apical-to-basolateral permeability of human brain endothelium to amyloid-beta Drug transport across the blood-brain barrier and the impact of breast cancer resistance protein (ABCG2). Clioquinol decreases amyloid-beta burden and reduces working memory impairment in a transgenic mouse model of Alzheimer's disease P-glycoprotein, breast cancer resistance protein, Organic Anion Transporter 3, and Transporting Peptide 1a4 during blood-brain barrier maturation: involvement of Wnt/β-catenin and endothelin-1 signaling The Inhibitor Ko143 Is Not Specific for ABCG2 In vivo and ex vivo regulation of breast cancer resistant protein (Bcrp) by peroxisome proliferator-activated receptor alpha (Pparα) at the blood-brain barrier PPAR-α, a lipid-sensing transcription factor, regulates blood-brain barrier efflux transporter expression. Ionophore and Biometal Modulation of P-glycoprotein Expression and Function in Human Brain Microvascular Endothelial Cells. Zinc chloride rapidly stimulates efflux transporters in renal proximal tubules of killifish (Fundulus heteroclitus). Effect of dietary copper addition on lipid metabolism in rabbits Impact of Zn2+ on ABC Transporter Function in Intact Isolated Rat Brain Microvessels, Human Brain Capillary Endothelial Cells, and in Rat in Vivo
author name string	wds:Q93257503-576223C2-CE02-4C6C-AE4A-4C0A469AF5E4 wds:Q93257503-61A2D56D-98AE-4DF1-A73A-C89AB8E910D4 wds:Q93257503-8FAACA2D-802D-4120-A469-B9A89A7C8FEC
author name string	Joseph A Nicolazzo Jennifer L Short Chris Yap
rdfs:label	A combination of clioquinol, zinc and copper increases the abundance and function of breast cancer resistance protein in human brain microvascular endothelial cells (en) A combination of clioquinol, zinc and copper increases the abundance and function of breast cancer resistance protein in human brain microvascular endothelial cells (nl)
skos:prefLabel	A combination of clioquinol, zinc and copper increases the abundance and function of breast cancer resistance protein in human brain microvascular endothelial cells (en) A combination of clioquinol, zinc and copper increases the abundance and function of breast cancer resistance protein in human brain microvascular endothelial cells (nl)
name	A combination of clioquinol, zinc and copper increases the abundance and function of breast cancer resistance protein in human brain microvascular endothelial cells (en) A combination of clioquinol, zinc and copper increases the abundance and function of breast cancer resistance protein in human brain microvascular endothelial cells (nl)
title	wds:Q93257503-0A244185-C010-4DE6-A5B4-1BC150E25676
title	A combination of clioquinol, zinc and copper increases the abundance and function of breast cancer resistance protein in human brain microvascular endothelial cells (en)
instance of	wds:Q93257503-F4DBEAA5-E79C-41AB-BD0C-7737D56274D8
instance of	scholarly article
PubMed ID	wds:Q93257503-C9FCEDDA-B2B4-4A77-9025-F9DF37D067E8
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/32339529
PubMed ID	32339529

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