About: Metabolite identification, tissue distribution, excretion and preclinical pharmacokinetic studies of ET-26-HCl, a new analogue of etomidate

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About: Metabolite identification, tissue distribution, excretion and preclinical pharmacokinetic studies of ET-26-HCl, a new analogue of etomidate Goto Sponge NotDistinct Permalink

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scientific article published on 12 February 2020

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rdf:type	Item
description	wetenschappelijk artikel (nl) artículu científicu espublizáu en febreru de 2020 (ast) im Februar 2020 veröffentlichter wissenschaftlicher Artikel (de) scientific article published on 12 February 2020 (en) 2020 թվականի փետրվարի 12-ին հրատարակված գիտական հոդված (hy) наукова стаття, опублікована 12 лютого 2020 (uk)
publication date	wds:Q91644280-8FFE6620-BFBD-40A7-AD5D-C0967CC99C38
publication date	2020-02-12 00:00:00Z (xsd:dateTime)
cites work	wds:Q91644280-2B2B9E31-BE64-4BB0-8CB5-BE48799A9208 wds:Q91644280-2F8F656C-982B-4B0E-8272-4EC7C80341A3 wds:Q91644280-3B2186FC-FD9B-41D8-B065-0690F749D037 wds:Q91644280-46B3904F-8530-48F9-B6EB-2C1CDCDCED4E wds:Q91644280-541FCA32-5B01-4683-A2B9-4AC1C1D16A5C wds:Q91644280-5FCB79EB-60E6-43FA-950C-E3EEDFFE5143 wds:Q91644280-6285C0E9-15F4-4DD9-9399-26A589252EC8 wds:Q91644280-6BA96CC7-EA5D-4D2E-B844-1B6312670CAA wds:Q91644280-70796B80-7294-4F71-BFE4-E0F1D47BB78C wds:Q91644280-7C69745B-6BC2-4DFD-99D3-CBD1F7E13566 wds:Q91644280-887C4446-8DB7-4D3A-9E0C-BD8DFB726BF1 wds:Q91644280-9CCBA83C-1BFD-4313-870C-F0CD72C84E23 wds:Q91644280-BB2CEF48-94CA-4924-91A6-0E17E386BE74 wds:Q91644280-C785A78F-03DC-4332-943F-B72A3780A32D wds:Q91644280-CC0B72FE-CD88-4334-98BC-7FB519E1026D wds:Q91644280-D10CAA53-F09F-46F7-B895-D012DE740A72 wds:Q91644280-D7E5028E-C686-49D8-9974-F84D8BF8AA63 wds:Q91644280-E4F6B63E-0D68-4BB4-AC16-83F0C9A351EC wds:Q91644280-F42C1FFD-A6A8-44F8-BB3D-4A4CE60A27DA wds:Q91644280-F4FA6C1F-C5FC-459E-8B99-329FC283662E
cites work	Carboxylesterase in the liver and small intestine of experimental animals and human Body size and metabolic rate Duration of adrenal inhibition following a single dose of etomidate in critically ill patients Plasma protein binding of etomidate in patients with renal failure or hepatic cirrhosis DL-1-(1-ARYLALKYL)IMIDAZOLE-5-CARBOXYLATE ESTERS. A NOVEL TYPE OF HYPNOTIC AGENTS The effect of etomidate on adrenal function in critical illness: a systematic review Etomidate is associated with mortality and adrenal insufficiency in sepsis: a meta-analysis*. Pros and cons of etomidate--more discussion than evidence? Comparative Pharmacokinetics of Coumarin Anticoagulants XIV: Relationship between Protein Binding, Distribution, and Elimination Kinetics of Warfarin in Rats The plasma protein binding and distribution of etomidate in dog, rat and human blood An Etomidate Analogue With Less Adrenocortical Suppression, Stable Hemodynamics, and Improved Behavioral Recovery in Rats. Pharmacokinetics, tissue distribution, and plasma protein binding study of chicoric acid by HPLC-MS/MS. Metabolite-inactive etomidate analogues alleviating suppression on adrenal function in Beagle dogs. Pharmacologic studies on ET-26 hydrochloride in a rat model of lipopolysaccharide-induced sepsis. Plasma protein binding and metabolic clearance of phenytoin in the rat Minimum infusion rate and adrenocortical function after continuous infusion of the novel etomidate analog ET-26-HCl in rats The etomidate analog ET-26 HCl retains superior myocardial performance: Comparisons with etomidate in vivo and in vitro. [Determination of plasma protein binding rate of vitexin] High hepatic exposure of furanocoumarins in Radix Angelica dahuricae is associated with transporter mediated active uptake. An HPLC tandem mass spectrometry for quantification of ET-26-HCl and its major metabolite in plasma and application to a pharmacokinetic study in rats.
author name string	wds:Q91644280-39710561-9BD8-4C0A-A4B5-A0F9510C374C wds:Q91644280-507E5760-DFA1-413E-AE17-43D3D526A441 wds:Q91644280-86FD2069-9B56-4A73-8D22-891238236D16 wds:Q91644280-87A8F570-4EB5-4B5D-A6F1-9B28C22755A1 wds:Q91644280-9FF30D27-1351-4C41-9E53-C9878B64D497 wds:Q91644280-E71CB0C5-1A37-494C-8422-9B78350552D3 wds:Q91644280-F8C161A3-1CCD-424D-96B8-7D0427F63A1E
author name string	Lu Yu Liang Zheng Xu Chen Wen Wen Xu Wen Sheng Zhang Xue Hua Jiang Ming Yu Xu
rdfs:label	Metabolite identification, tissue distribution, excretion and preclinical pharmacokinetic studies of ET-26-HCl, a new analogue of etomidate (en) Metabolite identification, tissue distribution, excretion and preclinical pharmacokinetic studies of ET-26-HCl, a new analogue of etomidate (nl)
skos:prefLabel	Metabolite identification, tissue distribution, excretion and preclinical pharmacokinetic studies of ET-26-HCl, a new analogue of etomidate (en) Metabolite identification, tissue distribution, excretion and preclinical pharmacokinetic studies of ET-26-HCl, a new analogue of etomidate (nl)
name	Metabolite identification, tissue distribution, excretion and preclinical pharmacokinetic studies of ET-26-HCl, a new analogue of etomidate (en) Metabolite identification, tissue distribution, excretion and preclinical pharmacokinetic studies of ET-26-HCl, a new analogue of etomidate (nl)
author	wds:Q91644280-63B10243-F10E-4143-9C65-2D79E4082F4A
author	Ling Wang
title	wds:Q91644280-90EFE274-5BA1-47C2-8CC6-9EFF73B0263D
title	Metabolite identification, tissue distribution, excretion and preclinical pharmacokinetic studies of ET-26-HCl, a new analogue of etomidate (en)
page(s)	wds:Q91644280-3724AF0C-EC19-4C49-B22F-AA0BAEB3497E
page(s)	191666
instance of	wds:Q91644280-E5DFB788-66F9-4CD3-9152-7109E8996EA6
instance of	scholarly article
main subject	wds:Q91644280-6369585A-FCBF-44AF-ABFC-C41F494FAAEF wds:Q91644280-AB580054-2D96-468F-B07C-F16623FDADB9
main subject	etomidate metabolite identification
PubMed ID	wds:Q91644280-3D72783D-1807-44F6-9E0C-47D0200BD3C7
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/32257329
PubMed ID	32257329
published in	wds:Q91644280-23B46EED-C0C7-4360-BC10-BCDFED2AE5E8
published in	Royal Society Open Science
issue	wds:Q91644280-234D625C-E8D9-4DD9-8D75-CEC4238663C9
volume	wds:Q91644280-7875061B-8810-4E91-B686-84E71C40AB4B
issue	2
volume	7
DOI	wds:Q91644280-67A48922-661D-45AF-BCE4-E66633F06E9C
DOI	http://dx.doi.org/10.1098/RSOS.191666
DOI	10.1098/RSOS.191666
PMCID	wds:Q91644280-4B98C03B-5CDD-4938-811C-3122B5423ED4
PMCID	7062083
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q91644280

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