About: Design, synthesis and biological evaluation of novel tetrahydroacridine pyridine- aldoxime and -amidoxime hybrids as efficient uncharged reactivators of nerve agent-inhibited human acetylcholinesterase

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About: Design, synthesis and biological evaluation of novel tetrahydroacridine pyridine- aldoxime and -amidoxime hybrids as efficient uncharged reactivators of nerve agent-inhibited human acetylcholinesterase Goto Sponge NotDistinct Permalink

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scientific article published on 15 March 2014

Attributes	Values
rdf:type	Item
description	wetenschappelijk artikel (nl) bài báo khoa học (vi) наукова стаття, опублікована в березні 2014 (uk) article scientifique publié en 2014 (fr) scientific article published on 15 March 2014 (en) artículu científicu espublizáu en marzu de 2014 (ast)
publication date	wds:Q87620231-B989CBE0-8281-4E0C-93C1-69346A3356D7
publication date	2014-03-15 00:00:00Z (xsd:dateTime)
author name string	wds:Q87620231-0E6F60D3-BD07-443E-BF5C-43B6FBB3B816 wds:Q87620231-1DF01859-8C5B-473D-B030-6F3ED6738508 wds:Q87620231-1F3DED8A-5381-4686-8676-57D237964AF5 wds:Q87620231-4A97404E-44C6-49A1-AE2B-B19CBECAA12C wds:Q87620231-56FD99FE-CCCC-49FA-8824-1C21B9692E28 wds:Q87620231-81828208-217B-4011-A1AB-616482D093F4 wds:Q87620231-C1AF167C-BC12-45D9-B305-FB00CDF4EABF wds:Q87620231-C5D30506-C31B-4BEE-B212-1E3420BB629F wds:Q87620231-D64AC012-AD2F-4A60-8FF0-AAB03B059A84
author name string	Jacques-Philippe Colletier Florian Nachon Mélanie Arboléas Julien Renou Rachid Baati Mélanie Loiodice Maria Kliachyna Benoit Sanson Valentin Nussbaum
rdfs:label	Design, synthesis and biological evaluation of novel tetrahydroacridine pyridine- aldoxime and -amidoxime hybrids as efficient uncharged reactivators of nerve agent-inhibited human acetylcholinesterase (en) Design, synthesis and biological evaluation of novel tetrahydroacridine pyridine- aldoxime and -amidoxime hybrids as efficient uncharged reactivators of nerve agent-inhibited human acetylcholinesterase (nl)
skos:prefLabel	Design, synthesis and biological evaluation of novel tetrahydroacridine pyridine- aldoxime and -amidoxime hybrids as efficient uncharged reactivators of nerve agent-inhibited human acetylcholinesterase (en) Design, synthesis and biological evaluation of novel tetrahydroacridine pyridine- aldoxime and -amidoxime hybrids as efficient uncharged reactivators of nerve agent-inhibited human acetylcholinesterase (nl)
name	Design, synthesis and biological evaluation of novel tetrahydroacridine pyridine- aldoxime and -amidoxime hybrids as efficient uncharged reactivators of nerve agent-inhibited human acetylcholinesterase (en) Design, synthesis and biological evaluation of novel tetrahydroacridine pyridine- aldoxime and -amidoxime hybrids as efficient uncharged reactivators of nerve agent-inhibited human acetylcholinesterase (nl)
author	wds:Q87620231-53EF718B-F172-40E2-9AF7-80E8A9BDBF59 wds:Q87620231-7BA55EA2-8122-4D35-B39D-437D56766881 wds:Q87620231-BD6295C5-6DEC-4F13-903A-8E58D4638753 wds:Q87620231-E6EF5944-4FC2-433B-A297-CF003921B5B6
author	Martin Weik Ludovic Jean Pierre-Yves Renard Gianluca Santoni
title	wds:Q87620231-3EA3433A-5F2E-49D1-97FF-2F7B3816FFFD
title	Design, synthesis and biological evaluation of novel tetrahydroacridine pyridine- aldoxime and -amidoxime hybrids as efficient uncharged reactivators of nerve agent-inhibited human acetylcholinesterase (en)
page(s)	wds:Q87620231-2776BFE0-DDA6-4B3D-BA5A-48970FB08680
page(s)	455-467
instance of	wds:Q87620231-744BC5A1-911B-48A1-8EAB-1DE637439578
instance of	scholarly article
PubMed ID	wds:Q87620231-5356C1A4-B799-4E05-AF81-E67718724CE0
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/24704618
PubMed ID	24704618
published in	wds:Q87620231-046BA8F7-1466-45FA-9C7D-050D0851A69C
published in	European Journal of Medicinal Chemistry
volume	wds:Q87620231-A47E1DA0-F2D1-4283-BB22-71D1D53B51C7
volume	78
DOI	wds:Q87620231-C22F598C-01E7-4D39-993E-AA54ABFE7506
DOI	http://dx.doi.org/10.1016/J.EJMECH.2014.03.044
DOI	10.1016/J.EJMECH.2014.03.044
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q87620231
is cites work of	Molecular Modeling and In Vitro Studies of a Neutral Oxime as a Potential Reactivator for Acetylcholinesterase Inhibited by Paraoxon The impact of crystallization conditions on structure-based drug design: A case study on the methylene blue/acetylcholinesterase complex Docking Studies, Synthesis, and In-vitro Evaluation of Novel Oximes Based on Nitrones as Reactivators of Inhibited Acetylcholinesterase. Quantitative analysis of amphiphilic N-alkyloxypyridinecarboximidamide by liquid chromatography-tandem mass spectrometry Pyridine and p-Nitrophenyl Oxime Esters with Possible Photochemotherapeutic Activity: Synthesis, DNA Photocleavage and DNA Binding Studies. Buchwald-Hartwig Amination Approach for the Synthesis of Functionalized 1,2,3,4-Tetrahydroacridine Derivatives Synthesis of 3-Hydroxy-4-Substituted Picolinonitriles from 4-Propargylaminoisoxazoles via Stepwise and One-Pot Isoxazolopyridine Formation/N-O Bond Cleavage Sequence
is cites work of	wds:Q59810491-0F87851D-EDED-46E3-A45A-11C671737CDB wds:Q47133421-6CF80A28-7007-4EDC-BBA8-4FAACA9E66F9 wds:Q38790814-CFE31E07-0817-42DC-8E66-30014A239FF2 wds:Q39909419-DD55B46D-3191-4CBB-B17F-C35A8349D005 wds:Q52861297-87DE310D-CC34-4A03-ACA4-BBBA6D1DFB90 wds:Q62476496-26BEA494-18A4-4895-801B-521DDBF2B3E6 wds:Q92933133-7292D1BF-299C-4E82-8A69-8300267D12B1

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