About: Phase I studies of AVE9633, an anti-CD33 antibody-maytansinoid conjugate, in adult patients with relapsed/refractory acute myeloid leukemia

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About: Phase I studies of AVE9633, an anti-CD33 antibody-maytansinoid conjugate, in adult patients with relapsed/refractory acute myeloid leukemia Goto Sponge NotDistinct Permalink

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scientific article published on 26 April 2011

Attributes	Values
rdf:type	Item
description	wetenschappelijk artikel (nl) наукова стаття, опублікована у квітні 2011 (uk) scientific article published on 26 April 2011 (en) artículu científicu espublizáu n'abril de 2011 (ast)
publication date	wds:Q83967551-667B216B-3837-40BD-8ADF-6006C8492D45
publication date	2011-04-26 00:00:00Z (xsd:dateTime)
exact match	wds:Q83967551-B3762515-0B72-48CC-90A9-DA176DEBFCFD
exact match	https://scigraph.springernature.com/pub.10.1007/s10637-011-9670-0
cites work	wds:Q83967551-015F46DC-4ACF-41A2-BECB-026A0FEEEC71 wds:Q83967551-394C369B-ED2E-4808-B7B2-EAE2D15FF1EF wds:Q83967551-5A839208-4FFA-432A-BE97-84199698C975 wds:Q83967551-7EDE0DDD-F22F-4731-BF3F-BAB2F03C320D wds:Q83967551-90B75A89-E3C3-432D-A5DB-58F260FDED41 wds:Q83967551-986DB512-9B99-4EAF-ADB7-6EA7760232BE wds:Q83967551-9D5E19B3-6E29-46DC-BF79-55DAF6B25AD4 wds:Q83967551-A4083C12-9ACD-4900-A1A1-B142182871C1 wds:Q83967551-A8B48412-DD3E-4AA3-95DC-E3AD228C3B20 wds:Q83967551-BB4050A1-8B64-46B9-92AF-445DC0EABCF6 wds:Q83967551-C9F9C206-6EEB-4C95-B5EC-E8EF5A01C382 wds:Q83967551-CFE5F2F3-338A-495D-B302-38AB94EA445F wds:Q83967551-DE863263-23F7-43F1-93DD-FDF245DD52B9 wds:Q83967551-E4C670F3-C134-4320-854C-4A3CF4606A77 wds:Q83967551-EE78E5A6-39A5-4DF0-A12B-0E3B328B5766
cites work	Revised recommendations of the International Working Group for Diagnosis, Standardization of Response Criteria, Treatment Outcomes, and Reporting Standards for Therapeutic Trials in Acute Myeloid Leukemia P-gp activity is a critical resistance factor against AVE9633 and DM4 cytotoxicity in leukaemia cell lines, but not a major mechanism of chemoresistance in cells from acute myeloid leukaemia patients Antimitotic Activity of the Potent Tumor Inhibitor Maytansine Acute myeloid leukemia in the elderly Recombinant immunotoxins for the treatment of chemoresistant hematologic malignancies. Acute leukemia in adolescents and young adults Acute myelogenous leukemia Selective ablation of acute myeloid leukemia using antibody-targeted chemotherapy: a phase I study of an anti-CD33 calicheamicin immunoconjugate Maytansine, a novel antileukemic ansa macrolide from Maytenus ovatus Antibody-maytansinoid conjugates are activated in targeted cancer cells by lysosomal degradation and linker-dependent intracellular processing. Analysis of P-glycoprotein-mediated membrane transport in human peripheral blood lymphocytes using the UIC2 shift assay. Maytansine Prognostic value of S-phase cells in AML patients The immunophenotype of 177 adults with acute myeloid leukemia: proposal of a prognostic score Binding of maytansine to tubulin: competition with other mitotic inhibitors
author name string	wds:Q83967551-0A127845-FAC5-40D9-96C6-B78BD8D7B967 wds:Q83967551-164E3991-946C-4CE3-90DE-CD70964BE156 wds:Q83967551-39AC2E17-51BD-4ECD-9B97-FBDF039CADC8 wds:Q83967551-4D4B3C2B-E066-4393-BE32-3CE9DF22D79E wds:Q83967551-6464EF21-AA11-4CDF-9B4D-65FE5A241FF5 wds:Q83967551-66EDEFD3-66F1-4875-B800-0CBC9D8FC9E5 wds:Q83967551-9978DBEB-B0E7-448B-A301-BB0873CD2FB9 wds:Q83967551-B8163D1A-568F-41FF-97E2-17437964260F wds:Q83967551-C7E743B5-971B-48D2-A7EA-F30542EB7AD7 wds:Q83967551-D9322333-6CD2-431B-88BA-1D8356B582FD wds:Q83967551-DCD7FE49-B16D-49E0-82A7-E11EB4E29E4E wds:Q83967551-F53B618F-8344-45C1-AFA2-9C02B84A709E
author name string	Xavier Thomas Francis J Giles Marie-Laure Ozoux Anne Vekhoff Daniel J DeAngelo Ollivier Legrand John M Lambert Jean-Pierre Marie Ruoping Tang Simona Lapusan Rodica Morariu-Zamfir Philippe Poncelet
rdfs:label	Phase I studies of AVE9633, an anti-CD33 antibody-maytansinoid conjugate, in adult patients with relapsed/refractory acute myeloid leukemia (en) Phase I studies of AVE9633, an anti-CD33 antibody-maytansinoid conjugate, in adult patients with relapsed/refractory acute myeloid leukemia (nl)
skos:prefLabel	Phase I studies of AVE9633, an anti-CD33 antibody-maytansinoid conjugate, in adult patients with relapsed/refractory acute myeloid leukemia (en) Phase I studies of AVE9633, an anti-CD33 antibody-maytansinoid conjugate, in adult patients with relapsed/refractory acute myeloid leukemia (nl)
name	Phase I studies of AVE9633, an anti-CD33 antibody-maytansinoid conjugate, in adult patients with relapsed/refractory acute myeloid leukemia (en) Phase I studies of AVE9633, an anti-CD33 antibody-maytansinoid conjugate, in adult patients with relapsed/refractory acute myeloid leukemia (nl)
author	wds:Q83967551-7B1CFBCE-4D1B-4FE2-A22C-348A91924881 wds:Q83967551-C0825CA4-C6F1-44E7-98A0-0A1689865F1A wds:Q83967551-C92A7D05-92C1-4FED-9D3F-4482B232A92C wds:Q83967551-D10CDA21-56D8-4D3F-B788-C3AEF03A2C78
author	Jesús San Miguel Stéphane de Botton Charles Dumontet María-Belén Vidriales
title	wds:Q83967551-EF4D9117-0B6A-40E7-902F-6239C93F7771
title	Phase I studies of AVE9633, an anti-CD33 antibody-maytansinoid conjugate, in adult patients with relapsed/refractory acute myeloid leukemia (en)
page(s)	wds:Q83967551-B9CBA69B-362B-4B63-9B84-2D8F1B422D56
page(s)	1121-1131
instance of	wds:Q83967551-CAA7AD26-5001-42C0-BAD2-1618A613C6BE
instance of	scholarly article
main subject	wds:Q83967551-67481885-7FA3-4C7A-97EB-034C7BE36B6B
main subject	acute myeloid leukemia
PubMed ID	wds:Q83967551-AFC0487B-2A3D-4809-91B2-24F4D8F4D0F7
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/21519855
PubMed ID	21519855
published in	wds:Q83967551-7300EE3A-D566-4352-9A7B-9AD32DBD5735
published in	Investigational New Drugs
issue	wds:Q83967551-74FED044-01EE-4CE6-BEE9-58DE20033752
volume	wds:Q83967551-3AAAF4F8-7F74-4299-949C-BA9F9E3C3623
issue	3
volume	30
DOI	wds:Q83967551-7A6EDEE0-642F-431A-8CF0-9D7FCA527F8B
DOI	http://dx.doi.org/10.1007/S10637-011-9670-0
DOI	10.1007/S10637-011-9670-0
Dimensions Publication ID	wds:Q83967551-55AC0C77-6B86-4809-9EC3-471965FE33C7
Dimensions Publication ID	1043629304
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q83967551

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