About: Development of autoimmunity against transcriptionally unrepressed target antigen in the thymus of Aire-deficient mice

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About: Development of autoimmunity against transcriptionally unrepressed target antigen in the thymus of Aire-deficient mice Goto Sponge NotDistinct Permalink

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scientific article published on 01 February 2005

Attributes	Values
rdf:type	Item
description	wetenschappelijk artikel (nl) article scientifique publié en 2005 (fr) наукова стаття, опублікована в лютому 2005 (uk) im Februar 2005 veröffentlichter wissenschaftlicher Artikel (de) artículu científicu espublizáu en febreru de 2005 (ast) artikull shkencor i botuar më 01 shkurt 2005 (sq) scientific article published on 01 February 2005 (en)
publication date	wds:Q81377810-06469279-1D28-4599-BA2F-B03A25106FFB
publication date	2005-02-01 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q81377810-A931A72C-84CD-40A5-A6DE-6BFB367F3040
language of work or name	English
author name string	wds:Q81377810-02ECC161-6952-4579-A3E6-6839B7FDBACE wds:Q81377810-16EB9DBD-4677-4999-862D-DF300C9DA085 wds:Q81377810-18D1B940-D481-48B9-8708-A6C1F2DE3B24 wds:Q81377810-276FB90B-3308-4227-A9C3-5CD145BA8D36 wds:Q81377810-3EF18BC1-002C-4BB6-9417-55870ECD6885 wds:Q81377810-49169AE5-1510-45B6-AD67-FDE9206E612E wds:Q81377810-49440477-CB91-461D-B834-7C5B798FF363 wds:Q81377810-55F164FE-DC97-4927-A103-1D513C458D66 wds:Q81377810-5E9BD9ED-3ACF-4752-861F-40B0BC54771D wds:Q81377810-617E92F3-A2EB-4630-A93B-A4EDC02D87E2 wds:Q81377810-65DAC106-CF79-478E-9E50-66FDB6F9D6CB wds:Q81377810-819CE06C-6EF4-4BD2-BA00-457F55046C75 wds:Q81377810-85FFE5B2-EAF8-4DEF-8386-2184ED91E570 wds:Q81377810-B8B7EB5D-6EFC-4AD9-B625-63FAD6AE9F66 wds:Q81377810-CEF5FDE4-8F05-4876-B25B-884745274DF9 wds:Q81377810-D7779BCC-5A41-4BE6-AEDA-3D9372820089 wds:Q81377810-E371341D-7A87-47A3-BC24-274411442831 wds:Q81377810-E89E1F46-FF9B-4AD1-BC0F-0A79366FBEBE wds:Q81377810-EB5102C4-D459-484D-BBFA-86D10ECC5BAD wds:Q81377810-FE38A75F-964F-4DAB-8C90-36A23327C14C
author name string	Mitsuru Matsumoto Hongwei Han Noriyuki Kuroda Yasuhiro Mouri Gen Yamada Fumiko Kajiura Yousuke Takahama Naozumi Ishimaru Tasuku Mitani Takeshi Takahashi Naoki Takeda Akemi Matsushima Keisuke Izumi Yoshimi Bando Yoshio Hayashi Rieko Arakaki Tomoo Ueno Takashi Nomura Shijie Sun Daisuke Uchida
rdfs:label	Development of autoimmunity against transcriptionally unrepressed target antigen in the thymus of Aire-deficient mice (en) Development of autoimmunity against transcriptionally unrepressed target antigen in the thymus of Aire-deficient mice (nl) Development of autoimmunity against transcriptionally unrepressed target antigen in the thymus of Aire-deficient mice (sq)
skos:prefLabel	Development of autoimmunity against transcriptionally unrepressed target antigen in the thymus of Aire-deficient mice (en) Development of autoimmunity against transcriptionally unrepressed target antigen in the thymus of Aire-deficient mice (nl) Development of autoimmunity against transcriptionally unrepressed target antigen in the thymus of Aire-deficient mice (sq)
name	Development of autoimmunity against transcriptionally unrepressed target antigen in the thymus of Aire-deficient mice (en) Development of autoimmunity against transcriptionally unrepressed target antigen in the thymus of Aire-deficient mice (nl) Development of autoimmunity against transcriptionally unrepressed target antigen in the thymus of Aire-deficient mice (sq)
author	wds:Q81377810-727CA79F-DAE8-44C9-9310-7CCF5B851199
author	Shimon Sakaguchi
title	wds:Q81377810-B317185B-122C-4ADF-AE5C-9D32EDA3CD3A
title	Development of autoimmunity against transcriptionally unrepressed target antigen in the thymus of Aire-deficient mice (en)
page(s)	wds:Q81377810-47BF08CD-742C-4A38-9C0C-FF5461D81CFB
page(s)	1862-1870
instance of	wds:Q81377810-5DBCB6D1-54B6-48B0-B6F3-BEBD3D86DE7E
instance of	scholarly article
PubMed ID	wds:Q81377810-7CF7BCF5-6A08-4A60-8344-6B36AB508FAC
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/15699112
PubMed ID	15699112
published in	wds:Q81377810-6D4EE30A-A8E3-44A3-BF29-72C5BA34C75D
published in	Journal of Immunology
issue	wds:Q81377810-42015F35-4D35-402E-A933-2FA521E8F129
volume	wds:Q81377810-7B52966F-DEAA-4DD6-A80D-1FC46E020834
issue	4
volume	174
DOI	wds:Q81377810-8F32A711-2D05-49C8-8A6E-29196E9C8A74
DOI	http://dx.doi.org/10.4049/JIMMUNOL.174.4.1862
DOI	10.4049/JIMMUNOL.174.4.1862
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q81377810
is cites work of	Primary immune deficiency disorders presenting as autoimmune diseases: IPEX and APECED. Modulation of Aire regulates the expression of tissue-restricted antigens Why Aire? Compensating for late bloomers Direct and indirect roles of the LTbetaR pathway in central tolerance induction. NF-kappaB2 is required for the control of autoimmunity by regulating the development of medullary thymic epithelial cells Hypothetical review: thymic aberrations and type-I interferons; attempts to deduce autoimmunizing mechanisms from unexpected clues in monogenic and paraneoplastic syndromes AIRE in the thymus and beyond The role of Aire in clonal selection Regulatory T cells exert checks and balances on self tolerance and autoimmunity Medullary thymic epithelial cells expressing Aire represent a unique lineage derived from cells expressing claudin. Central tolerance: learning self-control in the thymus Autoimmune regulator deficiency results in decreased expression of CCR4 and CCR7 ligands and in delayed migration of CD4+ thymocytes Alteration of intra-pancreatic target-organ specificity by abrogation of Aire in NOD mice A decade of AIRE. Generalized multi-organ autoimmunity in CCR7-deficient mice Aire controls the differentiation program of thymic epithelial cells in the medulla for the establishment of self-tolerance APECED: A Paradigm of Complex Interactions between Genetic Background and Susceptibility Factors Patient mutation in AIRE disrupts P-TEFb binding and target gene transcription

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