About: OPA1 cleavage depends on decreased mitochondrial ATP level and bivalent metals

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About: OPA1 cleavage depends on decreased mitochondrial ATP level and bivalent metals Goto Sponge NotDistinct Permalink

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scientific article published on 19 August 2007

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rdf:type	Item
description	wetenschappelijk artikel (nl) bài báo khoa học (vi) наукова стаття, опублікована в серпні 2007 (uk) scientific article published on 19 August 2007 (en) artículu científicu espublizáu n'agostu de 2007 (ast)
publication date	wds:Q81161420-AC2818FD-DA36-499B-A2BB-65F893BB80B2
publication date	2007-08-19 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q81161420-537945D9-89B4-477F-9482-9068335222B4
language of work or name	English
cites work	wds:Q81161420-00DB78A3-DC59-4C97-A082-207E84F8EDF1 wds:Q81161420-05AF9A05-7A46-429D-92AE-74DF57716561 wds:Q81161420-0E61D30E-8641-432F-B9CF-24B21B0B43F9 wds:Q81161420-13F840EF-1A2B-4FFD-8EF8-F3ADE1F0F82B wds:Q81161420-174FE36C-768A-4937-98D2-83CF1821A545 wds:Q81161420-30EBF9D9-01D7-4C3B-A6DE-C5B8390D1222 wds:Q81161420-48478B36-9D91-4F1A-B729-BC2F6859FB62 wds:Q81161420-4CF1F25A-7E45-4BAE-88C6-3FF8D5C1C835 wds:Q81161420-5CF5CD75-77E9-4B3C-A156-266DDDE90BB0 wds:Q81161420-628240A1-F9BB-4331-AA0F-9F4C76CC2C13 wds:Q81161420-7209F213-0D62-483D-A5AA-660A7BC228F0 wds:Q81161420-77F12EF7-3093-42D5-93CA-07781B34EC01 wds:Q81161420-7A5F1422-D0ED-4CE5-A7A3-1B72CFF4F58A wds:Q81161420-7B91185A-4C16-455B-ABAC-A6054D412F71 wds:Q81161420-7EBD986D-C3D9-4C89-ABDE-7A02211CC6E6 wds:Q81161420-7EC55987-3376-4BC1-B2DB-8DACD5748D3D wds:Q81161420-810F87EA-2A15-4CA0-A48B-893ED1A161D9 wds:Q81161420-8B3073B4-A83C-47EF-A655-83392B9C256C wds:Q81161420-A54003BF-7262-4A92-B56F-C02226CD5A57 wds:Q81161420-A572248A-6B9C-46C4-AE33-16B8D1D630FA wds:Q81161420-ABB66222-842F-40E3-BFE1-4A986AB2E4EC wds:Q81161420-B49C8E7D-340A-4048-8F23-B7B3D4A6D158 wds:Q81161420-C197E5D1-33EA-476D-AF97-FF2FACAC512C wds:Q81161420-C2EC4757-0DD9-4B1B-BAEB-D17377D9A547 wds:Q81161420-C3689BFB-0EB4-4217-8F2B-FF45C50F99F9 wds:Q81161420-CC64F6E9-6885-438F-B131-C28975C0E697 wds:Q81161420-CE12CD5E-61EE-4089-924C-02FD1C2E86C5 wds:Q81161420-D1128B2C-2451-4999-A59E-D0BABDB78C00 wds:Q81161420-D36112CA-B0AB-48E4-806A-02B1802C91AF wds:Q81161420-E51DF96B-7196-403C-AFA5-C5F8EB71E355
cites work	OPA1, encoding a dynamin-related GTPase, is mutated in autosomal dominant optic atrophy linked to chromosome 3q28 Nuclear gene OPA1, encoding a mitochondrial dynamin-related protein, is mutated in dominant optic atrophy Dynamin-related protein Drp1 is required for mitochondrial division in mammalian cells OPA1 requires mitofusin 1 to promote mitochondrial fusion Regulation of mitochondrial morphology through proteolytic cleavage of OPA1 Alternative topogenesis of Mgm1 and mitochondrial morphology depend on ATP and a functional import motor. Loss of the intermembrane space protein Mgm1/OPA1 induces swelling and localized constrictions along the lengths of mitochondria Deficit of in vivo mitochondrial ATP production in patients with Friedreich ataxia Mitochondrial rhomboid PARL regulates cytochrome c release during apoptosis via OPA1-dependent cristae remodeling Structure and dynamics of the mitochondrial inner membrane cristae A distinct pathway remodels mitochondrial cristae and mobilizes cytochrome c during apoptosis The human dynamin-related protein OPA1 is anchored to the mitochondrial inner membrane facing the inter-membrane space Iron levels in human retina: sex difference and increase with age Loss of OPA1 perturbates the mitochondrial inner membrane structure and integrity, leading to cytochrome c release and apoptosis Mutation spectrum and splicing variants in the OPA1 gene OPA1 alternate splicing uncouples an evolutionary conserved function in mitochondrial fusion from a vertebrate restricted function in apoptosis OPA1 controls apoptotic cristae remodeling independently from mitochondrial fusion Proteolytic processing of OPA1 links mitochondrial dysfunction to alterations in mitochondrial morphology OPA1 processing reconstituted in yeast depends on the subunit composition of the m-AAA protease in mitochondria Mitochondria: dynamic organelles in disease, aging, and development Effects of OPA1 mutations on mitochondrial morphology and apoptosis: relevance to ADOA pathogenesis Mitochondrial membrane potential regulates matrix configuration and cytochrome c release during apoptosis Ugo1p links the Fzo1p and Mgm1p GTPases for mitochondrial fusion Ultrastructural bases for metabolically linked mechanical activity in mitochondria. I. Reversible ultrastructural changes with change in metabolic steady state in isolated liver mitochondria Mitochondria in cell death: novel targets for neuroprotection and cardioprotection OPA1 R445H mutation in optic atrophy associated with sensorineural deafness. The mitochondrial inner membrane AAA metalloprotease family in metazoans eOPA1: an online database for OPA1 mutations. Reconstituted adenine nucleotide translocase forms a channel for small molecules comparable to the mitochondrial permeability transition pore Mitochondrial and nonmitochondrial reduction of MTT: interaction of MTT with TMRE, JC-1, and NAO mitochondrial fluorescent probes.
author name string	wds:Q81161420-53490157-3179-480F-8F93-252BCC1E432C wds:Q81161420-B0EEC749-8F1A-4FB8-8C18-FBB37D4228DD wds:Q81161420-ED48A35E-B999-4D6C-A509-53852CC93ED3 wds:Q81161420-F50CFF32-B6CF-4EA4-88A6-C0C2E0997219 wds:Q81161420-FCE0C044-CFCC-44F0-BACA-0DE652AB5FFD
author name string	Aurélien Olichon Annie Valette Florence Larminat Laurent Baricault Laurie Guégand
rdfs:label	OPA1 cleavage depends on decreased mitochondrial ATP level and bivalent metals (en) OPA1 cleavage depends on decreased mitochondrial ATP level and bivalent metals (nl)
skos:prefLabel	OPA1 cleavage depends on decreased mitochondrial ATP level and bivalent metals (en) OPA1 cleavage depends on decreased mitochondrial ATP level and bivalent metals (nl)
name	OPA1 cleavage depends on decreased mitochondrial ATP level and bivalent metals (en) OPA1 cleavage depends on decreased mitochondrial ATP level and bivalent metals (nl)
author	wds:Q81161420-2D49B1FE-1878-41C7-AC1C-2B42EEAEEAF1 wds:Q81161420-5BD5B1A4-436B-4104-BAB8-F256473D5A15
author	Guy Lenaers Bruno Ségui
title	wds:Q81161420-EFC13833-EB5E-407A-8280-1A86C704CEEF
title	OPA1 cleavage depends on decreased mitochondrial ATP level and bivalent metals (en)
page(s)	wds:Q81161420-09F150A7-DE8F-4650-A93B-05E39E1E768D
page(s)	3800-3808
instance of	wds:Q81161420-25999540-0B65-41D3-8C62-46CDB7023DE8
instance of	scholarly article
PubMed ID	wds:Q81161420-03F9E354-9FD5-4D07-A514-022394D1D539
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/17826766
PubMed ID	17826766
published in	wds:Q81161420-CD607DFC-2178-4C11-962C-34CA87FF76AB

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