About: A signal network involving coactivated NF-kappaB and STAT3 and altered p53 modulates BAX/BCL-XL expression and promotes cell survival of head and neck squamous cell carcinomas

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About: A signal network involving coactivated NF-kappaB and STAT3 and altered p53 modulates BAX/BCL-XL expression and promotes cell survival of head and neck squamous cell carcinomas Goto Sponge NotDistinct Permalink

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scientific article published on 01 May 2008

Attributes	Values
rdf:type	Item
description	wetenschappelijk artikel (nl) article scientifique publié en 2008 (fr) наукова стаття, опублікована в травні 2008 (uk) artículu científicu espublizáu en mayu de 2008 (ast) scientific article published on 01 May 2008 (en)
publication date	wds:Q80439910-F61A79B7-6D6C-4F9E-B26C-1F6EB3EF4A16
publication date	2008-05-01 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q80439910-DABA4187-3F7D-44D7-9B1A-99561AE0E3E7
language of work or name	English
cites work	wds:Q80439910-32FFA465-F005-4EBB-9D8E-537F1890A132 wds:Q80439910-E0FA9E21-8585-4090-AC8A-C0446BC0D511
cites work	Role of BAX in the apoptotic response to anticancer agents Bcl-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDAC
author name string	wds:Q80439910-00A1806C-DF29-4243-822A-A6AA75DAD864 wds:Q80439910-3CE75476-4BDE-4CB7-94F7-E4CBE48475F7 wds:Q80439910-4DB62EF5-E265-4CBB-BC89-AB40FE438700 wds:Q80439910-7C398480-4451-4444-8591-5C344825E3B4 wds:Q80439910-BC895CE7-3B28-4AF6-BDA7-6E87AF3BD82E wds:Q80439910-D915BE12-8076-441E-84BD-FFF1D2CD5232 wds:Q80439910-DFFD3733-D048-4B82-AF93-6C7A9C400FAC
author name string	Zhong Chen Xinping Yang Bin Yan Jay Friedman Carter Van Waes Ning T Yeh Jason Yeh
rdfs:label	A signal network involving coactivated NF-kappaB and STAT3 and altered p53 modulates BAX/BCL-XL expression and promotes cell survival of head and neck squamous cell carcinomas (en) A signal network involving coactivated NF-kappaB and STAT3 and altered p53 modulates BAX/BCL-XL expression and promotes cell survival of head and neck squamous cell carcinomas (nl)
skos:prefLabel	A signal network involving coactivated NF-kappaB and STAT3 and altered p53 modulates BAX/BCL-XL expression and promotes cell survival of head and neck squamous cell carcinomas (en) A signal network involving coactivated NF-kappaB and STAT3 and altered p53 modulates BAX/BCL-XL expression and promotes cell survival of head and neck squamous cell carcinomas (nl)
name	A signal network involving coactivated NF-kappaB and STAT3 and altered p53 modulates BAX/BCL-XL expression and promotes cell survival of head and neck squamous cell carcinomas (en) A signal network involving coactivated NF-kappaB and STAT3 and altered p53 modulates BAX/BCL-XL expression and promotes cell survival of head and neck squamous cell carcinomas (nl)
author	wds:Q80439910-EC26D25E-C443-462A-BB49-F6F4783DDF3C
author	Tin-Lap Lee
title	wds:Q80439910-496A2EBD-AFCF-46C0-82AA-E38358A6AD4C
title	A signal network involving coactivated NF-kappaB and STAT3 and altered p53 modulates BAX/BCL-XL expression and promotes cell survival of head and neck squamous cell carcinomas (en)
page(s)	wds:Q80439910-ECD46D0D-FB08-455D-9396-2BFCC3124DEF
page(s)	1987-1998
instance of	wds:Q80439910-C649DA43-8F7E-42D2-903C-E84988EE1E5F
instance of	scholarly article
main subject	wds:Q80439910-3EA241D6-B37D-45E6-8DAF-55FDE15068EC
main subject	NF-κB
PubMed ID	wds:Q80439910-0AD1F7D2-508D-4E76-96AE-EE4EBA21F82D
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/18172861
PubMed ID	18172861
published in	wds:Q80439910-3A0E5E59-BF8C-4F03-A4F8-BF1E51E9E073
published in	International Journal of Cancer
issue	wds:Q80439910-A811C896-2C4F-4F22-9340-C3134761BAF6
volume	wds:Q80439910-42FE7DEA-60A9-40E9-B698-B77F5615F340
issue	9
volume	122
number of pages	wds:Q80439910-47D84BF8-8542-4631-9038-F1D2800B5557
number of pages	12 (xsd:decimal)
DOI	wds:Q80439910-63030B98-944C-49C1-B689-6D0A090ADDEF
DOI	http://dx.doi.org/10.1002/IJC.23324
DOI	10.1002/IJC.23324
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q80439910
is cites work of	Apoptosis induction through proteasome inhibitory activity of cucurbitacin D in human T-cell leukemia ΔNp63 versatilely regulates a Broad NF-κB gene program and promotes squamous epithelial proliferation, migration, and inflammation Molecular targets for anticancer redox chemotherapy and cisplatin-induced ototoxicity: the role of curcumin on pSTAT3 and Nrf-2 signalling. Current and potential inflammation targeted therapies in head and neck cancer Attenuated transforming growth factor beta signaling promotes nuclear factor-kappaB activation in head and neck cancer. Degrasyn potentiates the antitumor effects of bortezomib in mantle cell lymphoma cells in vitro and in vivo: therapeutic implications Unraveling regulatory programs for NF-kappaB, p53 and microRNAs in head and neck squamous cell carcinoma TNF-α promotes c-REL/ΔNp63α interaction and TAp73 dissociation from key genes that mediate growth arrest and apoptosis in head and neck cancer Proteomic signatures of epidermal growth factor receptor and survival signal pathways correspond to gefitinib sensitivity in head and neck cancer. NF-κB and stat3 transcription factor signatures differentiate HPV-positive and HPV-negative head and neck squamous cell carcinoma Systems biology-defined NF-kappaB regulons, interacting signal pathways and networks are implicated in the malignant phenotype of head and neck cancer cell lines differing in p53 status Bortezomib up-regulates activated signal transducer and activator of transcription-3 and synergizes with inhibitors of signal transducer and activator of transcription-3 to promote head and neck squamous cell carcinoma cell death Signaling Networks of Activated Oncogenic and Altered Tumor Suppressor Genes in Head and Neck Cancer TGF-β and NF-κB signal pathway cross-talk is mediated through TAK1 and SMAD7 in a subset of head and neck cancers The Role of the NF-kappaB Transcriptome and Proteome as Biomarkers in Human Head and Neck Squamous Cell Carcinomas In vitro model for gastroduodenal reflux-induced nuclear factor-kappaB activation and its role in hypopharyngeal carcinogenesis CK2 modulation of NF-kappaB, TP53, and the malignant phenotype in head and neck cancer by anti-CK2 oligonucleotides in vitro or in vivo via sub-50-nm nanocapsules. GRIM-19 disrupts E6/E6AP complex to rescue p53 and induce apoptosis in cervical cancers Pivotal regulatory network and genes in osteosarcoma A STAT3-decoy oligonucleotide induces cell death in a human colorectal carcinoma cell line by blocking nuclear transfer of STAT3 and STAT3-bound NF-κB. Combination treatment with oxaliplatin and mangiferin causes increased apoptosis and downregulation of NFκB in cancer cell lines. Chemotherapeutic drugs and human tumor cells cytokine network Stat3 binds to mtDNA and regulates mitochondrial gene expression in keratinocytes Molecular and clinical responses in a pilot study of gefitinib with paclitaxel and radiation in locally advanced head-and-neck cancer Current update on established and novel biomarkers in salivary gland carcinoma pathology and the molecular pathways involved Off-target effects of plasmid-transcribed shRNAs on NFκB signaling pathway and cell survival of human melanoma cells. HSP90 Inhibitor SNX5422/2112 Targets the Dysregulated Signal and Transcription Factor Network and Malignant Phenotype of Head and Neck Squamous Cell Carcinoma Apoptotic body engulfment by hepatic stellate cells promotes their survival by the JAK/STAT and Akt/NF-kappaB-dependent pathways YAP dysregulation by phosphorylation or ΔNp63-mediated gene repression promotes proliferation, survival and migration in head and neck cancer subsets. MEK inhibitor PD-0325901 overcomes resistance to CK2 inhibitor CX-4945 and exhibits anti-tumor activity in head and neck cancer Sensitization of head and neck cancer to cisplatin through the use of a novel curcumin analog Induction of S phase arrest and apoptosis by ethyl acetate extract from Tetrastigma hemsleyanum in human hepatoma HepG2 cells. p70S6K promotes IL-6-induced epithelial-mesenchymal transition and metastasis of head and neck squamous cell carcinoma The In Vitro Effect of Acidic-Pepsin on Nuclear Factor KappaB Activation and Its Related Oncogenic Effect on Normal Human Hypopharyngeal Cells Inhibition of NF-κB prevents the acidic bile-induced oncogenic mRNA phenotype, in human hypopharyngeal cells. IL-11 Attenuates Liver Ischemia/Reperfusion Injury (IRI) through STAT3 Signaling Pathway in Mice Molecular biology of head and neck cancer: risks and pathways. Tocilizumab inhibits neuronal cell apoptosis and activates STAT3 in cerebral infarction rat model Non-invasive remote limb ischemic postconditioning protects rats against focal cerebral ischemia by upregulating STAT3 and reducing apoptosis. Curcumin Analogue CA15 Exhibits Anticancer Effects on HEp-2 Cells via Targeting NF-κB. Functional clustering of time series gene expression data by Granger causality

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