About: Structure-based design, synthesis, and SAR evaluation of a new series of 8-hydroxyquinolines as HIF-1alpha prolyl hydroxylase inhibitors

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About: Structure-based design, synthesis, and SAR evaluation of a new series of 8-hydroxyquinolines as HIF-1alpha prolyl hydroxylase inhibitors Goto Sponge NotDistinct Permalink

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scientific article published on 22 August 2006

Attributes	Values
rdf:type	Item
description	wetenschappelijk artikel (nl) article scientifique publié en 2006 (fr) наукова стаття, опублікована в серпні 2006 (uk) im August 2006 veröffentlichter wissenschaftlicher Artikel (de) scientific article published on 22 August 2006 (en) artículu científicu espublizáu n'agostu de 2006 (ast)
publication date	wds:Q80163778-33D12F46-0F9F-4A0A-BCDC-3AC123E6D14E
publication date	2006-08-22 00:00:00Z (xsd:dateTime)
author name string	wds:Q80163778-024F2BEF-9D7B-43A2-8BAC-BBC308DB4383 wds:Q80163778-126D04A6-D9AF-43DE-AB02-F7BD57B16D1C wds:Q80163778-348B700C-7A88-4434-950E-77F0E29C6E5B wds:Q80163778-713951B2-510C-4807-B2E9-5FE6D39A873C wds:Q80163778-720ED0CC-F175-41FD-824B-28B45AAE2D67 wds:Q80163778-7C21C9EE-EB0B-49AA-A236-A34076857F0F wds:Q80163778-9E929B85-1F3B-4734-8259-72BA3299E4E5 wds:Q80163778-A2134C87-2746-4780-9554-DDEC492FAB35 wds:Q80163778-A4827F14-2EE2-40B6-981C-2E13445A1220 wds:Q80163778-A5A3540B-88CE-4785-AD68-A59C1383022A wds:Q80163778-B3640128-BA27-4C01-A18C-7E27B51E7317 wds:Q80163778-CDBAA8F1-10E9-4DA8-9BC1-77E2EF1111D0 wds:Q80163778-CE818BA4-01CD-4C2F-8F71-9A7D17C85C65
author name string	Artem G Evdokimov Shengde Wu Matthew Pokross Richard Walter Kevin Xu Angelique Boyer Justin Sheville Marlene Mekel Namal C Warshakoon Richard Kawamoto Sean Renock Songtao Zhou Carol Winter
rdfs:label	Structure-based design, synthesis, and SAR evaluation of a new series of 8-hydroxyquinolines as HIF-1alpha prolyl hydroxylase inhibitors (en) Structure-based design, synthesis, and SAR evaluation of a new series of 8-hydroxyquinolines as HIF-1alpha prolyl hydroxylase inhibitors (nl)
skos:prefLabel	Structure-based design, synthesis, and SAR evaluation of a new series of 8-hydroxyquinolines as HIF-1alpha prolyl hydroxylase inhibitors (en) Structure-based design, synthesis, and SAR evaluation of a new series of 8-hydroxyquinolines as HIF-1alpha prolyl hydroxylase inhibitors (nl)
name	Structure-based design, synthesis, and SAR evaluation of a new series of 8-hydroxyquinolines as HIF-1alpha prolyl hydroxylase inhibitors (en) Structure-based design, synthesis, and SAR evaluation of a new series of 8-hydroxyquinolines as HIF-1alpha prolyl hydroxylase inhibitors (nl)
title	wds:Q80163778-A93123CA-4C07-4349-BE9D-8B8CFB4FE025
title	Structure-based design, synthesis, and SAR evaluation of a new series of 8-hydroxyquinolines as HIF-1alpha prolyl hydroxylase inhibitors (en)
page(s)	wds:Q80163778-63B45878-A474-4695-AAC1-E844D6001B5E
page(s)	5517-5522
instance of	wds:Q80163778-33152326-A0EA-485C-8B14-AC8A08E09719
instance of	scholarly article
PubMed ID	wds:Q80163778-79E84007-D3EA-446C-BA10-DC68B79B9687
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/16931007
PubMed ID	16931007
published in	wds:Q80163778-1E873ABD-308F-4E57-A7BB-AFE290254E43
published in	Bioorganic & Medicinal Chemistry Letters
issue	wds:Q80163778-0CEE9DF8-BB91-46C9-836D-BCB6171B1764
volume	wds:Q80163778-3B5E9DFF-DD1A-4052-8446-8C939432A577
issue	21
volume	16
DOI	wds:Q80163778-8A9C21FE-769C-4909-B1F0-8CFCB0590529
DOI	http://dx.doi.org/10.1016/J.BMCL.2006.08.040
DOI	10.1016/J.BMCL.2006.08.040
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q80163778
is cites work of	A photoreactive small-molecule probe for 2-oxoglutarate oxygenases Quantitative High-Throughput Screening Identifies 8-Hydroxyquinolines as Cell-Active Histone Demethylase Inhibitors High-throughput screening for inhibitors of Mycobacterium tuberculosis H37Rv Utilization of an in vivo reporter for high throughput identification of branched small molecule regulators of hypoxic adaptation Inhibition of oxygen sensors as a therapeutic strategy for ischaemic and inflammatory disease Cellular oxygen sensing in health and disease Dual-action inhibitors of HIF prolyl hydroxylases that induce binding of a second iron ion. Synthesis of a FTO inhibitor with anticonvulsant activity. Screening chelating inhibitors of HIF-prolyl hydroxylase domain 2 (PHD2) and factor inhibiting HIF (FIH) Gas phase reaction of substituted isoquinolines to carboxylic acids in ion trap and triple quadrupole mass spectrometers after electrospray ionization and collision-induced dissociation Discovery of a new molecular probe ML228: an activator of the hypoxia inducible factor (HIF) pathway Selective small molecule probes for the hypoxia inducible factor (HIF) prolyl hydroxylases Unusual mass spectrometric dissociation pathway of protonated isoquinoline-3-carboxamides due to multiple reversible water adduct formation in the gas phase Structural Insight into the Prolyl Hydroxylase PHD2: A Molecular Dynamics and DFT Study Recent Advances in Developing Inhibitors for Hypoxia-Inducible Factor Prolyl Hydroxylases and Their Therapeutic Implications. Ab Initio Structural Modeling of and Experimental Validation for Chlamydia trachomatis Protein CT296 Reveal Structural Similarity to Fe(II) 2-Oxoglutarate-Dependent Enzymes Hypoxia-inducible factor stabilizers and other small-molecule erythropoiesis-stimulating agents in current and preventive doping analysis Affinity-Based Fluorescence Polarization Assay for High-Throughput Screening of Prolyl Hydroxylase 2 Inhibitors Furan- and Thiophene-2-Carbonyl Amino Acid Derivatives Activate Hypoxia-Inducible Factor via Inhibition of Factor Inhibiting Hypoxia-Inducible Factor-1.
is cites work of	wds:Q39711306-40E71FAF-F1DF-440D-A7A6-6A4981BFB914 wds:Q46863123-C759767E-34D0-4CA1-9CF8-4F4EC589D96B wds:Q24598970-74F6B280-F77D-47B8-850A-C5452FB176F5 wds:Q34169514-FA1E14B4-6E69-49D1-96C5-B01FD459086C wds:Q43280297-1B729FF3-C852-4DD0-A18E-76A031F9C64D wds:Q56701681-4D2A1B32-D58C-41F3-A4ED-CC52AE5A45C7 wds:Q39244944-96221CD7-5191-430D-BCA3-2C460292A599 wds:Q33910748-A3D18F80-72DA-477C-B422-C2A178618F2A wds:Q27674686-B9D81B5F-164B-4126-ACCF-65D59AA8D67B wds:Q36367302-64CA328A-426F-4986-A2F9-55D93E365F81 wds:Q42040042-CC7BC76F-F116-42DF-9991-CEBA307706A8 wds:Q52594204-6AE9CD41-3ED8-4D22-B83E-6C4B9921CC74 wds:Q27666155-384630E4-0505-4DA6-902A-B0AEC7C10DD0 wds:Q33503956-D6BCB9FF-807D-4205-998B-D9B94B080326 wds:Q36978952-D6954D13-DC2D-4442-A377-3E8A73FD9E02 wds:Q38648760-8A707209-0007-404F-A95C-DAB45F4AF40A wds:Q33402434-E503B8C3-EF4E-48E3-AC93-BD400CB4003A wds:Q34102211-2A6727B4-22E2-474B-9E76-E6BD2A4B0FE8 wds:Q27684637-0ADA19D0-CE59-47E4-9FAC-20604BC5A493

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