About: C-Type natriuretic peptide

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About: C-Type natriuretic peptide Goto Sponge NotDistinct Permalink

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class of chemical compounds

Attributes	Values
rdf:type	Item
description	class of chemical compounds (en) клас хімічних сполук (uk)
rdfs:label	C-Type natriuretic peptide (en)
skos:prefLabel	C-Type natriuretic peptide (en)
name	C-Type natriuretic peptide (en)
isomeric SMILES	wds:Q78190979-C011F272-8090-4BF7-B947-E6B0B0397D34
isomeric SMILES	CC[C@H](C)[C@H]1C(=O)NCC(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)NCC(=O)N[C@@H](CSSC[C@@H](C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N1)CCCNC(=N)N)CC(=O)O)CC(C)C)CCCCN)CC(C)C)CC2=CC=CC=C2)NC(=O)CNC(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)CN)C(=O)O)CC(C)C)CO)CCSC)CO
instance of	wds:Q78190979-089117e0-4605-fa4c-4739-8a5732d84392
instance of	type of chemical entity
subclass of	wds:Q78190979-e92e8073-4916-d353-05c1-08c5ee54e232
subclass of	natriuretic peptide
UniChem compound ID	wds:Q78190979-12D04FD6-9F50-4CE8-A0FE-92AB1DB977C8
Probes And Drugs ID	wds:Q78190979-C6374A87-838F-4D37-99F4-FB2F00AEB4B6
CAS Registry Number	wds:Q78190979-cda7674c-4663-2fbf-7885-8697b72bec0d
canonical SMILES	wds:Q78190979-a41edc1c-4ccf-c208-16fb-97f082281771
InChI	wds:Q78190979-19B96B60-8AD5-4B51-B1B1-9A0904CB06F7
InChIKey	wds:Q78190979-2908C814-DFE1-42DB-B394-11926E480717
chemical formula	wds:Q78190979-458785D6-5357-42E1-A28C-945DA5E69778
DSSTox substance ID	wds:Q78190979-81A7303D-490B-4170-AF1A-7A3F04B3D166
PubChem CID	wds:Q78190979-79E9C7F8-F335-49D3-AB4E-A6F20F181113
KEGG ID	wds:Q78190979-b7cf1c65-4d21-f35c-e01d-96b1bec32f62
ChEBI ID	wds:Q78190979-9d3ab9c5-4762-6f6a-c43a-b841baf35ba0
DSSTOX compound identifier	wds:Q78190979-A4FCADE2-C745-41EE-B729-BAB821E45086
PubChem CID	http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID16179407
KEGG ID	http://www.kegg.jp/entry/C16005
ChEBI ID	http://purl.obolibrary.org/obo/CHEBI_80235
UniChem compound ID	22912120
Probes And Drugs ID	PD076254
CAS Registry Number	127869-51-6
canonical SMILES	CCC(C)C1C(=O)NCC(=O)NC(C(=O)NC(C(=O)NC(C(=O)NCC(=O)NC(C(=O)NCC(=O)NC(CSSCC(C(=O)NC(C(=O)NCC(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1)CCCNC(=N)N)CC(=O)O)CC(C)C)CCCCN)CC(C)C)CC2=CC=CC=C2)NC(=O)CNC(=O)C(CCCCN)NC(=O)C(CO)NC(=O)C(CC(C)C)NC(=O)CN)C(=O)O)CC(C)C)CO)CCSC)CO
InChI	InChI=1S/C93H157N27O28S3/c1-12-52(10)76-91(146)104-42-72(127)108-65(44-122)88(143)114-57(26-30-149-11)82(137)118-64(43-121)80(135)103-39-70(125)106-58(31-48(2)3)78(133)101-41-74(129)110-68(92(147)148)47-151-150-46-67(109-73(128)40-100-77(132)54(23-16-18-27-94)111-89(144)66(45-123)119-85(140)59(32-49(4)5)105-69(124)37-96)90(145)116-62(35-53-21-14-13-15-22-53)79(134)102-38-71(126)107-60(33-50(6)7)84(139)112-55(24-17-19-28-95)81(136)115-61(34-51(8)9)86(141)117-63(36-75(130)131)87(142)113-56(83(138)120-76)25-20-29-99-93(97)98/h13-15,21-22,48-52,54-68,76,121-123H,12,16-20,23-47,94-96H2,1-11H3,(H,100,132)(H,101,133)(H,102,134)(H,103,135)(H,104,146)(H,105,124)(H,106,125)(H,107,126)(H,108,127)(H,109,128)(H,110,129)(H,111,144)(H,112,139)(H,113,142)(H,114,143)(H,115,136)(H,116,145)(H,117,141)(H,118,137)(H,119,140)(H,120,138)(H,130,131)(H,147,148)(H4,97,98,99)/t52-,54-,55-,56-,57-,58-,59-,60-,61-,62-,63-,64-,65-,66-,67-,68-,76-/m0/s1
InChIKey	UHSBKBYWHCBDCJ-DYGWFTAGSA-N
chemical formula	C₉₃H₁₅₇N₂₇O₂₈S₃
DSSTox substance ID	DTXSID60155686
PubChem CID	16179407
KEGG ID	C16005
ChEBI ID	80235
DSSTOX compound identifier	DTXCID9078177
skos:altLabel	CNP (en)
mass	wds:Q78190979-4B78BEE5-8B7B-43B0-83A8-AA8D556473D5
mass	2196.0853503839985 (xsd:decimal)
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q78190979
is main subject of	C-type natriuretic peptide in chronic renal failure and its action in humans C-type natriuretic peptide-induced vasodilation is dependent on hyperpolarization in human forearm resistance vessels Furin-mediated Processing of Pro-C-type Natriuretic Peptide Receptor selectivity of natriuretic peptide family, atrial natriuretic peptide, brain natriuretic peptide, and C-type natriuretic peptide A single-nucleotide polymorphism in C-type natriuretic peptide gene may be associated with hypertension C-type natriuretic peptide (CNP) is the major natriuretic peptide in human cerebrospinal fluid Dwarfism and early death in mice lacking C-type natriuretic peptide C-type natriuretic peptide has a negative inotropic effect on cardiac myocytes Effects of C-type natriuretic peptide on rat cardiac contractility Increased effects of C-type natriuretic peptide on contractility and calcium regulation in murine hearts overexpressing cyclic GMP-dependent protein kinase I. Four functionally distinct C-type natriuretic peptides found in fish reveal evolutionary history of the natriuretic peptide system. Direct chronotropic effects of atrial and C-type natriuretic peptides in anaesthetized dogs C-type natriuretic peptide in vascular physiology and disease. Heart specific up-regulation of genes for B-type and C-type natriuretic peptide receptors in diabetic mice. Endothelial production of C-type natriuretic peptide and its marked augmentation by transforming growth factor-beta. Possible existence of "vascular natriuretic peptide system" Concentrations and molecular forms of C-type natriuretic peptide in brain and cerebrospinal fluid Isolation and identification of C-type natriuretic peptide in human monocytic cell line, THP-1 C-type natriuretic peptide receptor expression in pancreatic alpha cells C-type natriuretic peptide and guanylyl cyclase B receptor C-type natriuretic peptide concentrations in the plasma and cerebrospinal fluid of patients with subarachnoid hemorrhage Human C-type natriuretic peptide. Characterization of the gene and peptide C-type natriuretic peptide (CNP) in rats and humans C-type natriuretic peptide Response of human artery, vein, and cultured smooth muscle cells to atrial and C-type natriuretic peptides Isolation, mapping, and regulated expression of the gene encoding mouse C-type natriuretic peptide A genome-wide association study of northwestern Europeans involves the C-type natriuretic peptide signaling pathway in the etiology of human height variation Identification of a potent serum factor that causes desensitization of the receptor for C-Type natriuretic peptide Gene Expression, Secretion, and Autocrine Action of C-Type Natriuretic Peptide in Cultured Adult Rat Cardiac Fibroblasts A novel cardiac hormone related to A-, B- and C-type natriuretic peptides Local expression of C-type natriuretic peptide markedly suppresses neointimal formation in rat injured arteries through an autocrine/paracrine loop Seminal plasma factors that cause large elevations in cellular cyclic GMP are C-type natriuretic peptides. Increased renal production of C-type natriuretic peptide (CNP) in patients with cirrhosis and functional renal failure C-type natriuretic peptide (CNP) effects on intracellular calcium [Ca2+]i in mouse gonadotrope-derived alphaT3-1 cell line Plasma C-type natriuretic peptide forms and thyroid status in prepubertal children with acquired thyroid disease. Amino-terminal propeptide of C-type natriuretic peptide (NTproCNP) predicts height velocity in healthy children Systemic administration of C-type natriuretic peptide as a novel therapeutic strategy for skeletal dysplasias C-Type natriuretic peptide/guanylate cyclase B system in rat osteogenic ROB-C26 cells and its down-regulation by dexamethazone Biomechanical signals and the C-type natriuretic peptide counteract catabolic activities induced by IL-1β in chondrocyte/agarose constructs Dexamethasone stimulates expression of C-type Natriuretic Peptide in chondrocytes Significance of C-type natriuretic peptide (CNP) in endochondral ossification: analysis of CNP knockout mice C-type natriuretic peptide/guanylate cyclase B system in ATDC5 cells, a chondrogenic cell line Selective Activation of the B Natriuretic Peptide Receptor by C-Type Natriuretic Peptide (CNP) Endothelium-derived C-type natriuretic peptide: more than just a hyperpolarizing factor Natriuretic peptide receptor-3 underpins the disparate regulation of endothelial and vascular smooth muscle cell proliferation by C-type natriuretic peptide Natriuretic peptide receptor-C regulates coronary blood flow and prevents myocardial ischemia/reperfusion injury: novel cardioprotective role for endothelium-derived C-type natriuretic peptide Identification of a novel osteoblastic gene, inducible by C-type natriuretic peptide, whose transcript might function in mineralization as a noncoding RNA. Release of C-type natriuretic peptide accounts for the biological activity of endothelium-derived hyperpolarizing factor C-type natriuretic peptide (CNP) is a bifurcation factor for sensory neurons. Cloning and sequence analysis of a Bothrops jararaca cDNA encoding a precursor of seven bradykinin-potentiating peptides and a C-type natriuretic peptide Molecular cloning and chromosomal assignment of the mouse C-type natriuretic peptide (CNP) gene (Nppc): comparison with the human CNP gene (NPPC) C-type natriuretic peptide inhibits leukocyte recruitment and platelet-leukocyte interactions via suppression of P-selectin expression Physiological levels of A-, B- and C-type natriuretic peptide shed the endothelial glycocalyx and enhance vascular permeability Mutant phenotype analysis suggests potential roles for C-type natriuretic peptide receptor (NPR-B) in male mouse fertility D-Amino acid residue in the C-type natriuretic peptide from the venom of the mammal, Ornithorhynchus anatinus, the Australian platypus Effect of C-Type Natriuretic Peptide on Maturation and Developmental Competence of Goat Oocytes Matured In Vitro The aging heart, myocardial fibrosis, and its relationship to circulating C-type natriuretic Peptide C-type natriuretic peptide and heart failure

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