About: Combined expression of multidrug resistance protein (MRP) and glutathione S-transferase P1-1 (GSTP1-1) in MCF7 cells and high level resistance to the cytotoxicities of ethacrynic acid but not oxazaphosphorines or cisplatin

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About: Combined expression of multidrug resistance protein (MRP) and glutathione S-transferase P1-1 (GSTP1-1) in MCF7 cells and high level resistance to the cytotoxicities of ethacrynic acid but not oxazaphosphorines or cisplatin Goto Sponge NotDistinct Permalink

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scientific article published on 01 October 1998

Attributes	Values
rdf:type	Item
description	wetenschappelijk artikel (nl) наукова стаття, опублікована в жовтні 1998 (uk) article scientifique publié en 1998 (fr) im Oktober 1998 veröffentlichter wissenschaftlicher Artikel (de) artículu científicu espublizáu n'ochobre de 1998 (ast) scientific article published on 01 October 1998 (en)
publication date	wds:Q77425117-4AF2F03B-FF37-4805-B2E0-CE5A1108FD4B
publication date	1998-10-01 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q77425117-D3716B99-9E74-4338-871F-12781B85609C
language of work or name	English
cites work	wds:Q77425117-0228E1FA-9B8A-4815-92B5-E718D677C63D wds:Q77425117-1155C29B-9557-49EE-8252-6DCE321EAF36 wds:Q77425117-1C2435E2-EE53-4A53-8F57-745D63490B7C wds:Q77425117-1CAF7175-F903-4DA1-8357-E785163F6E4D wds:Q77425117-276018ED-8CAD-4551-A849-E427CF247FE4 wds:Q77425117-3428F947-CB8B-410A-A157-18BAED65CC75 wds:Q77425117-34CE8E42-FBE1-46CA-B107-33AED8CAE1DD wds:Q77425117-390A17AF-EF5A-45DA-A2F9-9EC39A23DFFA wds:Q77425117-3C338D0C-032A-459A-8C7C-4AD1EE4EC0E7 wds:Q77425117-44977C7F-7327-45F5-A9CE-3EAE48B1BBA9 wds:Q77425117-47E70976-88A0-407C-92E0-6030D112A9A5 wds:Q77425117-4B274990-4158-4575-9007-BD3BD25287D9 wds:Q77425117-5F5817DE-2508-4920-887F-619C821BE91F wds:Q77425117-635A5A79-653D-4052-9F88-9DE46AFEFBD5 wds:Q77425117-6A301DE7-DC67-4B96-BC49-4D0E064F41A8 wds:Q77425117-82B9C087-3E38-4172-9E53-A7CE0EB1407D wds:Q77425117-9022F637-690B-4F90-94C4-6EE89CFB61E4 wds:Q77425117-91DBCCF5-91F8-41E4-9534-98637E3B8256 wds:Q77425117-9A8FA15C-F965-48E2-953E-63863CD06AEB wds:Q77425117-9FDECC68-C6A5-41DB-A534-1DA23A785E5D wds:Q77425117-A2D5674C-DB55-48F0-9D50-C6FF4EC32791 wds:Q77425117-A7123793-D304-434D-A123-0A9F7B74A7AD wds:Q77425117-BD0B543C-CF69-4468-B58A-008309CA35E1 wds:Q77425117-C45FCBB6-8F0D-4D24-B47F-1DE91AE30B18 wds:Q77425117-CFCAA291-E07B-4524-8CE1-344E81B20063 wds:Q77425117-D89F971C-79F1-4D7C-BB29-BE11F06B11F3 wds:Q77425117-D977C624-3757-42AB-BA51-FB68C363E08E wds:Q77425117-DB152121-706C-4905-A759-653FF43459A2 wds:Q77425117-E0595DBA-D4FE-40DC-B1EA-8288F10DBC2F wds:Q77425117-E3C0C114-0C94-4376-8363-94D025EBB92E wds:Q77425117-EDD718D3-A71D-497E-8441-5EA6C361FA1B wds:Q77425117-F1E50A04-8F4F-42C6-A5E6-2D582E3878BC
cites work	Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione: applications to mammalian blood and other tissues Detoxication of base propenals and other alpha, beta-unsaturated aldehyde products of radical reactions and lipid peroxidation by human glutathione transferases The glutathione S-transferase supergene family: regulation of GST and the contribution of the isoenzymes to cancer chemoprotection and drug resistance New colorimetric cytotoxicity assay for anticancer-drug screening Molecular cloning, characterization, and expression in Escherichia coli of full-length cDNAs of three human glutathione S-transferase Pi gene variants. Evidence for differential catalytic activity of the encoded proteins. Identification of genetic polymorphisms at the glutathione S-transferase Pi locus and association with susceptibility to bladder, testicular and prostate cancer Glutathione S-transferase (transferase π) from human placenta is identical or closely related to glutathione S-transferase (transferase ϱ) from erythrocytes Overexpression of the gene encoding the multidrug resistance-associated protein results in increased ATP-dependent glutathione S-conjugate transport. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding Acrolein-induced oxygen radical formation Glutathione transferases--structure and catalytic activity The role of glutathione and glutathione transferases in chemical carcinogenesis Multidrug resistance protein and glutathione S-transferase P1-1 act in synergy to confer protection from 4-nitroquinoline 1-oxide toxicity. Transport of the glutathione conjugate of ethacrynic acid by the human multidrug resistance protein MRP Isolation of the human anionic glutathione S-transferase cDNA and the relation of its gene expression to estrogen-receptor content in primary breast cancer The role of glutathione-dependent enzymes in drug resistance Glutathione conjugate mediated toxicities Coordinated induction of MRP/GS-X pump and gamma-glutamylcysteine synthetase by heavy metals in human leukemia cells Multidrug resistance protein (MRP)-mediated transport of leukotriene C4 and chemotherapeutic agents in membrane vesicles. Demonstration of glutathione-dependent vincristine transport Glutathione conjugation of the cytostatic drug ifosfamide and the role of human glutathione S-transferases. Inhibition of rat and human glutathione S-transferase isoenzymes by ethacrynic acid and its glutathione conjugate. Significance of an unusually low Km for glutathione in glutathione transferases of the alpha, mu and pi classes Effects of chronic ethacrynic acid exposure on glutathione conjugation and MRP expression in human colon tumor cells Biosynthesis, bioactivation, and mutagenicity of S-conjugates Chlorambucil-monoglutathionyl conjugate is sequestered by human alpha class glutathione S-transferases Increased levels of glutathione S-transferase π transcript as a mechanism of resistance to ethacrynic acid Ethacrynic acid and its glutathione conjugate as inhibitors of glutathione S-transferases The interaction of glutathione with 4-hydroxycyclophosphamide and phosphoramide mustard, studied by 31P nuclear magnetic resonance spectroscopy. Biosynthesis and cellular effects of toxic glutathione S-conjugates Protection by transfected glutathione S-transferase isozymes against carcinogen-induced alkylation of cellular macromolecules in human MCF-7 cells Drug resistance to cis-diamminedichloroplatinum (II) in Chinese hamster ovary cell lines transfected with glutathione S-transferase pi gene Studies on the basis for the toxicity of acrolein mercapturates
author name string	wds:Q77425117-6DB26397-4364-4E23-BF57-AAF58FAA7FC5 wds:Q77425117-909490B8-7755-4205-BB9C-93662E79DD17 wds:Q77425117-D62C42E5-5BC6-4541-83DF-5C787F065592
author name string	A J Townsend C S Morrow P K Smitherman
rdfs:label	Combined expression of multidrug resistance protein (MRP) and glutathione S-transferase P1-1 (GSTP1-1) in MCF7 cells and high level resistance to the cytotoxicities of ethacrynic acid but not oxazaphosphorines or cisplatin (en) Combined expression of multidrug resistance protein (nl)
skos:prefLabel	Combined expression of multidrug resistance protein (MRP) and glutathione S-transferase P1-1 (GSTP1-1) in MCF7 cells and high level resistance to the cytotoxicities of ethacrynic acid but not oxazaphosphorines or cisplatin (en) Combined expression of multidrug resistance protein (nl)
name	Combined expression of multidrug resistance protein (MRP) and glutathione S-transferase P1-1 (GSTP1-1) in MCF7 cells and high level resistance to the cytotoxicities of ethacrynic acid but not oxazaphosphorines or cisplatin (en) Combined expression of multidrug resistance protein (nl)
title	wds:Q77425117-3E17DD88-57C0-4FC2-A3D0-2E23BA86093F
title	Combined expression of multidrug resistance protein (MRP) and glutathione S-transferase P1-1 (GSTP1-1) in MCF7 cells and high level resistance to the cytotoxicities of ethacrynic acid but not oxazaphosphorines or cisplatin (en)
page(s)	wds:Q77425117-8250907E-35BD-4479-87C7-9C44E75421CC
page(s)	1013-1021
instance of	wds:Q77425117-BE6414CB-6D82-4CA3-8CC1-E32AFD18AB59
instance of	scholarly article
main subject	wds:Q77425117-3C05DCAB-2869-4C9B-8A09-E8EE732367F5 wds:Q77425117-4BECE7D5-B884-4AFB-8D8B-DF72DC092D08
main subject	multiple drug resistance cisplatin
PubMed ID	wds:Q77425117-76EEBEC2-4DBD-4E48-AF43-1F15E171E21F
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/9776312
PubMed ID	9776312

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