About: Zidovudine (AZT) causes an oxidation of mitochondrial DNA in mouse liver

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About: Zidovudine (AZT) causes an oxidation of mitochondrial DNA in mouse liver Goto Sponge NotDistinct Permalink

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scientific article published on 01 March 1999

Attributes	Values
rdf:type	Item
description	wetenschappelijk artikel (nl) bài báo khoa học (vi) наукова стаття, опублікована в березні 1999 (uk) article scientifique publié en 1999 (fr) im März 1999 veröffentlichter wissenschaftlicher Artikel (de) artículu científicu espublizáu en marzu de 1999 (ast) scientific article published on 01 March 1999 (en)
publication date	wds:Q74530061-18308464-7233-4504-8DB3-BB1A4E3583ED
publication date	1999-03-01 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q74530061-FCBA42FB-6377-453A-8BAA-9CBB497DD6FE
language of work or name	English
cites work	wds:Q74530061-0503587E-4476-4FEE-9874-2D90F5D7B0C8 wds:Q74530061-09ED324B-AFD3-45B8-AE8A-8F7A32B380C2 wds:Q74530061-18EED857-4709-4C17-BCB8-E657BAD0D2F4 wds:Q74530061-1CA74E90-8CFD-498B-9AEF-6308CCF2EE7D wds:Q74530061-248B6B0D-85E2-4E6F-8E09-986EA1D93F5F wds:Q74530061-2CC4BBEB-D9F9-4730-9126-80507A829973 wds:Q74530061-3F0229B4-2957-40F5-B9B1-90FA313C9A54 wds:Q74530061-48AE84EF-4E4E-4F02-ACA8-54237DEB3BF0 wds:Q74530061-49DC0AEB-F4EB-4E20-8243-EF4BA8D36C9C wds:Q74530061-4DA46EFB-870F-4D89-9202-9307687F517C wds:Q74530061-501E7FF0-2C2B-4CAC-B009-AD921E07F998 wds:Q74530061-5E17928E-9AD0-4BEE-A699-7A73CD0B3D47 wds:Q74530061-71F8D17C-D4FB-453E-8614-6DA4407D6FE0 wds:Q74530061-7839A5A5-69C4-4DD9-827A-9CC35DAC50FE wds:Q74530061-B29D5461-35C4-4DF6-AB5D-038B6F089C44 wds:Q74530061-BC283EFA-C61D-4606-BBF9-845E964E2DF8 wds:Q74530061-BE09EC8B-1CFB-43EB-8029-6E34314860C0 wds:Q74530061-D04C0BA8-289F-4C98-A30D-A51E625C5FD4 wds:Q74530061-E0A34B08-B254-4E81-AB7E-9F372F1C0C86 wds:Q74530061-EA7663AB-D0E6-4126-848C-7C247BB43435 wds:Q74530061-EE32D82D-7DDD-47CB-932E-142CF982926D
cites work	Clinical pharmacology of 3'-azido-2',3'-dideoxythymidine (zidovudine) and related dideoxynucleosides Phosphorylation of 3'-azido-3'-deoxythymidine and selective interaction of the 5'-triphosphate with human immunodeficiency virus reverse transcriptase Depletion of muscle mitochondrial DNA in AIDS patients with zidovudine-induced myopathy Mitochondrial myopathy caused by long-term zidovudine therapy Zidovudine induces molecular, biochemical, and ultrastructural changes in rat skeletal muscle mitochondria AZT treatment induces molecular and ultrastructural oxidative damage to muscle mitochondria. Prevention by antioxidant vitamins Normal oxidative damage to mitochondrial and nuclear DNA is extensive Sequence and gene organization of mouse mitochondrial DNA Mitochondrial Membrane Potential in Living Cells Oxidative Decay of DNA Evaluation of 2',7'-dichlorofluorescin and dihydrorhodamine 123 as fluorescent probes for intracellular H2O2 in cultured endothelial cells Oxidative damage to mitochondria is mediated by the Ca(2+)-dependent inner-membrane permeability transition Seminars in medicine of the Beth Israel Hospital, Boston. Mitochondrial DNA and disease Assays of oxidative DNA damage biomarkers 8-oxo-2'-deoxyguanosine and 8-oxoguanine in nuclear DNA and biological fluids by high-performance liquid chromatography with electrochemical detection The development of mitochondrial medicine Detection and quantification of oxidative adducts of mitochondrial DNA. Evolution of mitochondrial DNA in Drosophila subobscura. Hepatic Morphological alterations induced by zidovudine (ZDV) in an experimental model Concurrent zidovudine-induced myopathy and hepatoxicity in patients treated for human immunodeficiency virus (HIV) infection Zidovudine-induced hepatotoxicity Massive conversion of guanosine to 8-hydroxy-guanosine in mouse liver mitochondrial DNA by administration of azidothymidine
author name string	wds:Q74530061-022F26BF-0124-4269-A1DE-35426A9CAB9C wds:Q74530061-37938B8E-E10A-4256-A33B-7852704A0F68 wds:Q74530061-4A655E18-D7AB-4027-BA31-731AFD5391B7 wds:Q74530061-5A16036A-EE1A-49C9-B9F2-1992AF3E102F wds:Q74530061-9C81925F-CE7F-42BB-83C4-65713BF2A1D3
author name string	Sastre J Viña J del Olmo ML Pallardó FV de la Asunción JG
rdfs:label	Zidovudine (AZT) causes an oxidation of mitochondrial DNA in mouse liver (en) Zidovudine (AZT) causes an oxidation of mitochondrial DNA in mouse liver (nl)
skos:prefLabel	Zidovudine (AZT) causes an oxidation of mitochondrial DNA in mouse liver (en) Zidovudine (AZT) causes an oxidation of mitochondrial DNA in mouse liver (nl)
name	Zidovudine (AZT) causes an oxidation of mitochondrial DNA in mouse liver (en) Zidovudine (AZT) causes an oxidation of mitochondrial DNA in mouse liver (nl)
title	wds:Q74530061-944FE6C3-32ED-405E-AC0F-7B98FF6A3CA7
title	Zidovudine (AZT) causes an oxidation of mitochondrial DNA in mouse liver (en)
page(s)	wds:Q74530061-93013B62-C804-461B-BEEE-407D631925DE
page(s)	985-987
instance of	wds:Q74530061-A988B603-20D4-44A5-A3B2-187001A90B75
instance of	scholarly article
main subject	wds:Q74530061-C5E50902-AF03-40BE-A68F-0917CF2638BF
main subject	wd:Q198504
PubMed ID	wds:Q74530061-072DD914-F1E7-463A-88C3-8680B39EE531
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/10051507
PubMed ID	10051507
published in	wds:Q74530061-FF0A85DF-A787-47A4-BB66-4A4A51628CCC
published in	Hepatology
issue	wds:Q74530061-50A9A199-DDA6-4504-B908-D6D5227A7A87
volume	wds:Q74530061-BE0DD959-D7F5-4446-9358-73FE495F6620
issue	3
volume	29
DOI	wds:Q74530061-E86F84E4-5E20-4DFF-BE75-51AAE0D28153
DOI	http://dx.doi.org/10.1002/HEP.510290353
DOI	10.1002/HEP.510290353
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q74530061
is cites work of	The Importance of Patient-Specific Factors for Hepatic Drug Response and Toxicity Mechanisms of genotoxicity of nucleoside reverse transcriptase inhibitors Assessment of mitochondrial toxicity in human cells treated with tenofovir: comparison with other nucleoside reverse transcriptase inhibitors Pharmacology of nucleoside and nucleotide reverse transcriptase inhibitor-induced mitochondrial toxicity. Mitochondrial toxicity of nrti antiviral drugs: an integrated cellular perspective Mitochondrial dysfunction and nucleoside reverse transcriptase inhibitor therapy: experimental clarifications and persistent clinical questions Zidovudine (AZT) and hepatic lipid accumulation: implication of inflammation, oxidative and endoplasmic reticulum stress mediators Apoptosis and apoptosis-associated perturbations of peripheral blood lymphocytes during HIV infection: comparison between AIDS patients and asymptomatic long-term non-progressors. Mitochondrial DNA in aging and degenerative disease

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