About: beta-catenin is a downstream effector of Wnt-mediated tumorigenesis in the mammary gland

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About: beta-catenin is a downstream effector of Wnt-mediated tumorigenesis in the mammary gland Goto Sponge NotDistinct Permalink

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scientific article published on 01 August 2001

Attributes	Values
rdf:type	Item
description	wetenschappelijk artikel (nl) наукова стаття, опублікована в серпні 2001 (uk) im August 2001 veröffentlichter wissenschaftlicher Artikel (de) artículu científicu espublizáu n'agostu de 2001 (ast) scientific article published on 01 August 2001 (en)
publication date	wds:Q74434651-9B3C8E6B-273B-452F-A89C-9383811CD74E
publication date	2001-08-01 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q74434651-8DB3098E-C37E-4794-ABD7-44E15EAB210B
language of work or name	English
exact match	wds:Q74434651-27E3CB94-50E9-45DE-A697-3610F463BD73
exact match	https://scigraph.springernature.com/pub.10.1038/sj.onc.1204586
cites work	wds:Q74434651-1278EBE6-3CBF-4F6A-BB71-F887714BF5C8 wds:Q74434651-16543A54-C8D9-418C-83DC-DAEF180E3A97 wds:Q74434651-17E83B2D-E3EB-4613-BE72-E5792A151729 wds:Q74434651-21656FF0-7F54-4791-B4CA-812596357E70 wds:Q74434651-29DCCA89-27AD-4983-B6FA-4523B101618A wds:Q74434651-32B8C614-379C-4912-836B-B90A016D14E2 wds:Q74434651-462C60B2-A97F-4AA1-8DC3-C44E1AA47ECA wds:Q74434651-4EED25D4-210F-4DB1-A610-FF83164BA3BC wds:Q74434651-53ADC808-98B9-40D6-B9BB-F89819801A95 wds:Q74434651-5B012D8D-0273-49D8-A40A-98143FF755FB wds:Q74434651-6FAE29E5-DCCC-4053-898B-F890315E6CB9 wds:Q74434651-75142D46-2B99-4119-9E14-9CB3C2FA5C5C wds:Q74434651-82F08BAF-8BF8-452E-8F89-E92544378AB4 wds:Q74434651-99F9709F-BA79-4C36-B143-7D48810399F1 wds:Q74434651-B0117C10-50B1-400E-80A1-09A9AE3F01C4 wds:Q74434651-B2DA3AF3-E0DC-429F-9379-333C94B32EE7 wds:Q74434651-BAEA6813-D9EA-441F-8FCC-15F9E0B53D8B wds:Q74434651-CF82146C-9F62-4214-8FE1-7C434665E485 wds:Q74434651-D62F3F9A-BECE-4922-8674-E72C31520D0B wds:Q74434651-D8D4AF54-07F1-4221-BA96-1039811D7995 wds:Q74434651-DA521756-A2E3-4EA2-A3AF-252BAFE05309 wds:Q74434651-E8595956-EECB-4E8E-A120-19FC24FE5957 wds:Q74434651-EBF8B905-8A91-4391-8F9C-98AF01383D3E wds:Q74434651-EDE76E7B-D038-4679-81E7-16AD68312B32 wds:Q74434651-F4DBC4F0-57DE-419C-AC64-C7B35BE41C34 wds:Q74434651-F53F8AAC-9507-4E7B-9EB2-B197287F87B1 wds:Q74434651-FB3E06D1-5860-4141-8463-A1048670C452
cites work	Adenomatous polyposis coli protein contains two nuclear export signals and shuttles between the nucleus and cytoplasm WISP genes are members of the connective tissue growth factor family that are up-regulated in wnt-1-transformed cells and aberrantly expressed in human colon tumors Armadillo coactivates transcription driven by the product of the Drosophila segment polarity gene dTCF Modulation of transcriptional regulation by LEF-1 in response to Wnt-1 signaling and association with beta-catenin De Novo hair follicle morphogenesis and hair tumors in mice expressing a truncated beta-catenin in skin Regulation of cyclooxygenase-2 and periostin by Wnt-3 in mouse mammary epithelial cells Beta-catenin, a novel prognostic marker for breast cancer: its roles in cyclin D1 expression and cancer progression Expression of the int-1 gene in transgenic mice is associated with mammary gland hyperplasia and adenocarcinomas in male and female mice Identification of a mouse homolog of the human BTEB2 transcription factor as a beta-catenin-independent Wnt-1-responsive gene Nuclear-cytoplasmic shuttling of APC regulates beta-catenin subcellular localization and turnover The APC tumour suppressor has a nuclear export function. The role of beta-catenin in cell adhesion, signal transduction, and cancer. Identification of c-MYC as a target of the APC pathway Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells Lessons from hereditary colorectal cancer The cyclin D1 gene is a target of the beta-catenin/LEF-1 pathway Intestinal polyposis in mice with a dominant stable mutation of the beta-catenin gene Deletion of an amino-terminal sequence beta-catenin in vivo and promotes hyperphosporylation of the adenomatous polyposis coli tumor suppressor protein The oncogenic activation of beta-catenin Neoplastic transformation of RK3E by mutant beta-catenin requires deregulation of Tcf/Lef transcription but not activation of c-myc expression NH2-terminal deletion of beta-catenin results in stable colocalization of mutant beta-catenin with adenomatous polyposis coli protein and altered MDCK cell adhesion Differential transformation of mammary epithelial cells by Wnt genes An in vivo structure-function study of armadillo, the beta-catenin homologue, reveals both separate and overlapping regions of the protein required for cell adhesion and for wingless signaling Wnt-10b directs hypermorphic development and transformation in mammary glands of male and female mice. Effects of forced expression of an NH2-terminal truncated beta-Catenin on mouse intestinal epithelial homeostasis A retrovirus vector expressing the putative mammary oncogene int-1 causes partial transformation of a mammary epithelial cell line ApcMin, a mutation in the murine Apc gene, predisposes to mammary carcinomas and focal alveolar hyperplasias
author name string	wds:Q74434651-38AC2868-B33D-46A1-8482-D972A4BA2A02 wds:Q74434651-E6927DE1-DBAF-492C-98BB-18F77F656D0C
author name string	Leder P Michaelson JS
rdfs:label	beta-catenin is a downstream effector of Wnt-mediated tumorigenesis in the mammary gland (en) beta-catenin is a downstream effector of Wnt-mediated tumorigenesis in the mammary gland (nl)
skos:prefLabel	beta-catenin is a downstream effector of Wnt-mediated tumorigenesis in the mammary gland (en) beta-catenin is a downstream effector of Wnt-mediated tumorigenesis in the mammary gland (nl)
name	beta-catenin is a downstream effector of Wnt-mediated tumorigenesis in the mammary gland (en) beta-catenin is a downstream effector of Wnt-mediated tumorigenesis in the mammary gland (nl)
title	wds:Q74434651-9D944EBD-5D40-4455-835B-4AACB391683D
title	beta-catenin is a downstream effector of Wnt-mediated tumorigenesis in the mammary gland (en)
page(s)	wds:Q74434651-425C54B3-D4B5-42CA-B6C2-B9EAB3C003BB
page(s)	5093-5099
instance of	wds:Q74434651-0237DE0A-3737-4E84-80C0-672FE62B50C5
instance of	scholarly article
PubMed ID	wds:Q74434651-15172DAD-226D-4F2E-9C32-029D79F6B38F
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/11526497
PubMed ID	11526497
published in	wds:Q74434651-7BD08AA2-2316-40BD-97F2-1ED4A6594699
published in	Oncogene
issue	wds:Q74434651-90EE1562-4D62-45BF-AC44-B9B0FD11DD9F
volume	wds:Q74434651-AB8E2F28-A26E-4C06-B939-DE617DA7FFCD
issue	37
volume	20
DOI	wds:Q74434651-D2D5A86B-7E1B-4758-9588-A78CCC0A48C1
DOI	http://dx.doi.org/10.1038/SJ.ONC.1204586
DOI	10.1038/SJ.ONC.1204586
Dimensions Publication ID	wds:Q74434651-72F5663C-4E30-43BD-90C7-24C968261537
Dimensions Publication ID	1026819363
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q74434651
is cites work of	p21-activated Kinase-1 Signaling Mediates Cyclin D1 Expression in Mammary Epithelial and Cancer Cells O-GlcNAc-glycosylation of beta-catenin regulates its nuclear localization and transcriptional activity Wnt signaling promotes oncogenic transformation by inhibiting c-Myc-induced apoptosis

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