About: Evaluation and mapping of the DNA binding and oligomerization domains of the IE2 regulatory protein of human cytomegalovirus using yeast one and two hybrid interaction assays

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About: Evaluation and mapping of the DNA binding and oligomerization domains of the IE2 regulatory protein of human cytomegalovirus using yeast one and two hybrid interaction assays Goto Sponge NotDistinct Permalink

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scientific article published on 01 March 1998

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rdf:type	Item
description	wetenschappelijk artikel (nl) наукова стаття, опублікована в березні 1998 (uk) article scientifique publié en 1998 (fr) im März 1998 veröffentlichter wissenschaftlicher Artikel (de) artículu científicu espublizáu en marzu de 1998 (ast) scientific article published on 01 March 1998 (en)
publication date	wds:Q74386271-F11746B8-32BE-4674-AE0F-D4424A65D340
publication date	1998-03-01 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q74386271-01FF930A-B276-482C-8C33-93EDD055FD2F
language of work or name	English
cites work	wds:Q74386271-13EAA654-2378-47A7-82E8-43D51C6EFC20 wds:Q74386271-1690A7A2-D005-4AC7-B073-AA4867ED3FFA wds:Q74386271-1AAE1CCD-EAD1-4F24-AD3D-64BFD75AD4CA wds:Q74386271-1B12E5C9-F5A7-48FC-AFAA-28ACF170320B wds:Q74386271-36D1F42A-2D6E-4801-A8AB-879B6AAE66C5 wds:Q74386271-376F09DD-D504-40FB-8A4E-BA5C58EEBB24 wds:Q74386271-3CA03298-E54C-482F-AEBF-67CDCF0F6546 wds:Q74386271-5F513AE5-0807-4A59-8161-5FF49A5FB698 wds:Q74386271-66140E6A-D1AD-4087-8690-828BC4B51D91 wds:Q74386271-68E6A1C2-D82D-4375-90D2-E1F4AEB1CF25 wds:Q74386271-76F36961-DE2A-475D-8BA2-CEBBC01D519B wds:Q74386271-83E108BB-99D0-44EC-8D58-56617A64A26C wds:Q74386271-8EB939A0-E23E-4842-9337-25C9F349830B wds:Q74386271-99E87C14-8EDC-4965-B0C3-7609E347A66A wds:Q74386271-A3F8133B-D996-4E03-9244-FAF527A2CE1B wds:Q74386271-A94E4A8B-244D-4645-9D1E-D1830F857F27 wds:Q74386271-BED7B5D1-3A3D-4498-B15E-534C6F4F3823 wds:Q74386271-E827EC55-2BD7-4BE2-99AA-150597B8722B wds:Q74386271-F5486F80-9350-42A0-A55E-84F4C394F167
cites work	The retinoblastoma protein associates with the protein phosphatase type 1 catalytic subunit Molecular cloning of the olfactory neuronal transcription factor Olf-1 by genetic selection in yeast Fusion of Escherichia coli lacZ to the cytochrome c gene of Saccharomyces cerevisiae Functional interaction between the HCMV IE2 transactivator and the retinoblastoma protein. Potential role of human cytomegalovirus and p53 interaction in coronary restenosis The human cytomegalovirus 80-kilodalton but not the 72-kilodalton immediate-early protein transactivates heterologous promoters in a TATA box-dependent mechanism and interacts directly with TFIID. Temporal Patterns of Human Cytomegalovirus Transcription: Mapping the Viral RNAs Synthesized at Immediate Early, Early, and Late Times After Infection A cis-acting element in the major immediate-early (IE) promoter of human cytomegalovirus is required for negative regulation by IE2 Direct interaction of the human cytomegalovirus IE86 protein with the cis repression signal does not preclude TBP from binding to the TATA box. An in vitro system for human cytomegalovirus immediate early 2 protein (IE2)-mediated site-dependent repression of transcription and direct binding of IE2 to the major immediate early promoter Human cytomegalovirus ie2 negatively regulates alpha gene expression via a short target sequence near the transcription start site The IE2 gene products of human cytomegalovirus specifically down-regulate expression from the major immediate-early promoter through a target sequence located near the cap site Human cytomegalovirus IE86 protein interacts with promoter-bound TATA-binding protein via a specific region distinct from the autorepression domain The human cytomegalovirus 86K immediate early (IE) 2 protein requires the basic region of the TATA-box binding protein (TBP) for binding, and interacts with TBP and transcription factor TFIIB via regions of IE2 required for transcriptional regulatio Identification of a human cytomegalovirus virus DNA segment that complements an adenovirus 5 immediate early mutant Identification and mapping of dimerization and DNA-binding domains in the C terminus of the IE2 regulatory protein of human cytomegalovirus Minor groove contacts are essential for an interaction of the human cytomegalovirus IE2 protein with its DNA target Human cytomegalovirus immediate-early gene 2 protein interacts with itself and with several novel cellular proteins Structural Organization of the Spliced Immediate-Early Gene Complex that Encodes the Major Acidic Nuclear (IE1) and Transactivator (IE2) Proteins of African Green Monkey Cytomegalovirus.
author name string	wds:Q74386271-264232CA-3E45-4B48-8489-BB3D97289E55 wds:Q74386271-7363A874-09C7-4AB4-BBAF-ADC255C16EBE wds:Q74386271-98C3229E-3FF4-4F82-9F89-EBD8F3B11C18
author name string	J H Ahn G S Hayward C J Chiou
rdfs:label	Evaluation and mapping of the DNA binding and oligomerization domains of the IE2 regulatory protein of human cytomegalovirus using yeast one and two hybrid interaction assays (en) Evaluation and mapping of the DNA binding and oligomerization domains of the IE2 regulatory protein of human cytomegalovirus using yeast one and two hybrid interaction assays (nl)
skos:prefLabel	Evaluation and mapping of the DNA binding and oligomerization domains of the IE2 regulatory protein of human cytomegalovirus using yeast one and two hybrid interaction assays (en) Evaluation and mapping of the DNA binding and oligomerization domains of the IE2 regulatory protein of human cytomegalovirus using yeast one and two hybrid interaction assays (nl)
name	Evaluation and mapping of the DNA binding and oligomerization domains of the IE2 regulatory protein of human cytomegalovirus using yeast one and two hybrid interaction assays (en) Evaluation and mapping of the DNA binding and oligomerization domains of the IE2 regulatory protein of human cytomegalovirus using yeast one and two hybrid interaction assays (nl)
title	wds:Q74386271-04E49ECD-FD9C-4CB4-8D42-E1061F2B6A01
title	Evaluation and mapping of the DNA binding and oligomerization domains of the IE2 regulatory protein of human cytomegalovirus using yeast one and two hybrid interaction assays (en)
page(s)	wds:Q74386271-A5B43066-5160-4154-B93A-FC51F5EBAD37
page(s)	25-36
instance of	wds:Q74386271-A61C70A1-F8EA-4C59-B749-3A26E52989B9
instance of	scholarly article
PubMed ID	wds:Q74386271-16A26E83-ACFE-45C4-BD73-88C4ED9EF5D8
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/9524210
PubMed ID	9524210
published in	wds:Q74386271-50389BA4-FB0D-4F60-8806-57B3E14F2E90
published in	Gene
issue	wds:Q74386271-55F32AAD-455F-400A-8F00-48207380E0DB
volume	wds:Q74386271-18BE34D3-2F25-4CAF-9C8B-B3862258ABED
issue	1
volume	210
DOI	wds:Q74386271-E04E803B-1CED-47BE-A9B7-E326CB83C098
DOI	http://dx.doi.org/10.1016/S0378-1119(98)00056-0
DOI	10.1016/S0378-1119(98)00056-0
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q74386271
is cites work of	Disruption of PML subnuclear domains by the acidic IE1 protein of human cytomegalovirus is mediated through interaction with PML and may modulate a RING finger-dependent cryptic transactivator function of PML Human cytomegalovirus major immediate early 1 protein targets host chromosomes by docking to the acidic pocket on the nucleosome surface Functional properties of the human cytomegalovirus IE86 protein required for transcriptional regulation and virus replication The autoregulatory and transactivating functions of the human cytomegalovirus IE86 protein use independent mechanisms for promoter binding The putative zinc finger of the human cytomegalovirus IE2 86-kilodalton protein is dispensable for DNA binding and autorepression, thereby demarcating a concise core domain in the C terminus of the protein Small internal deletions in the human cytomegalovirus IE2 gene result in nonviable recombinant viruses with differential defects in viral gene expression. The human cytomegalovirus IE2 and UL112-113 proteins accumulate in viral DNA replication compartments that initiate from the periphery of promyelocytic leukemia protein-associated nuclear bodies (PODs or ND10) Development of cell lines that provide tightly controlled temporal translation of the human cytomegalovirus IE2 proteins for complementation and functional analyses of growth-impaired and nonviable IE2 mutant viruses PIAS1 enhances SUMO-1 modification and the transactivation activity of the major immediate-early IE2 protein of human cytomegalovirus Proteasome-independent disruption of PML oncogenic domains (PODs), but not covalent modification by SUMO-1, is required for human cytomegalovirus immediate-early protein IE1 to inhibit PML-mediated transcriptional repression. Evaluation of interactions of human cytomegalovirus immediate-early IE2 regulatory protein with small ubiquitin-like modifiers and their conjugation enzyme Ubc9 Viable human cytomegalovirus recombinant virus with an internal deletion of the IE2 86 gene affects late stages of viral replication Role of noncovalent SUMO binding by the human cytomegalovirus IE2 transactivator in lytic growth Internal deletions of IE2 86 and loss of the late IE2 60 and IE2 40 proteins encoded by human cytomegalovirus affect the levels of UL84 protein but not the amount of UL84 mRNA or the loading and distribution of the mRNA on polysomes Activation of transcription of the human cytomegalovirus early UL4 promoter by the Ets transcription factor binding element Crystal structure of the DNA-binding domain of human herpesvirus 6A immediate early protein 2. Inhibition of IL-1beta transcription by peptides derived from the hCMV IE2 transactivator Bright and Early: Inhibiting Human Cytomegalovirus by Targeting Major Immediate-Early Gene Expression or Protein Function
is cites work of	wds:Q34055426-EE508591-C003-4C0A-9F07-6DC318D6521C wds:Q39764411-40F275F1-DDAA-4F95-B54A-59E68E0E9B4C

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