About: SPARC/osteonectin is a frequent target for aberrant methylation in pancreatic adenocarcinoma and a mediator of tumor-stromal interactions

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About: SPARC/osteonectin is a frequent target for aberrant methylation in pancreatic adenocarcinoma and a mediator of tumor-stromal interactions Goto Sponge NotDistinct Permalink

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scientific article published on 01 August 2003

Attributes	Values
rdf:type	Item
description	wetenschappelijk artikel (nl) наукова стаття, опублікована в серпні 2003 (uk) im August 2003 veröffentlichter wissenschaftlicher Artikel (de) artículu científicu espublizáu n'agostu de 2003 (ast) scientific article published on 01 August 2003 (en)
publication date	wds:Q73767192-A455C668-C4F6-40CB-B9A3-73D3BB81EFED
publication date	2003-08-01 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q73767192-487C86B5-E8F9-4473-B1DC-103316DBC304
language of work or name	English
exact match	wds:Q73767192-1C8E13DC-A8C0-4E82-8857-8AEEC1E31723
exact match	https://scigraph.springernature.com/pub.10.1038/sj.onc.1206807
cites work	wds:Q73767192-0537B03F-E85F-4D70-B0E4-FF79F37BB521 wds:Q73767192-05621CA7-8602-4B35-874E-4C6F92496451 wds:Q73767192-1253C206-B1FD-4A9C-9CA2-561A204114E3 wds:Q73767192-16915AD1-B500-4D11-B228-8FF6A0D27353 wds:Q73767192-24C403D6-8227-4249-A1DE-E8AB7FC24899 wds:Q73767192-3643E2F5-2CE6-4231-A477-9F21B5DAE868 wds:Q73767192-3BB3DE9E-AB50-439D-9505-73E8CC89FDA1 wds:Q73767192-47653E3E-2D60-4AED-ABFA-7206D931F13C wds:Q73767192-4C6E6D71-64F5-43C9-A034-5E2F80983A81 wds:Q73767192-4EDDDD7B-0B8A-48CC-9E99-06B485BC9765 wds:Q73767192-5087765C-92C7-4199-BD38-22A2948EC102 wds:Q73767192-54A5BBC3-081F-4FF3-AF66-3667B3AA0F44 wds:Q73767192-55BB3148-4522-40A6-9A28-8E15FB8F05AF wds:Q73767192-566EAF0C-9DD5-4414-A80B-57E4B90A3238 wds:Q73767192-57487E7B-BE4F-460E-AFDC-07093D5A59EB wds:Q73767192-5EF913D5-C418-42D4-A3F6-D87217BA4184 wds:Q73767192-6427A4BD-6BB8-42A1-BCAF-48D28A790EE1 wds:Q73767192-802810B3-247C-4C40-9266-60F0D81D3411 wds:Q73767192-825D6BBA-4EB5-42C0-877C-8809D61D0A1D wds:Q73767192-8F840E0C-BCB9-421F-87DF-69FECB1263F4 wds:Q73767192-941CC041-9FA9-4B36-B403-B0D4DF075319 wds:Q73767192-A146BD91-B4FE-46B7-B70C-A94FBC0376F9
cites work	Exploring the host desmoplastic response to pancreatic carcinoma: gene expression of stromal and neoplastic cells at the site of primary invasion SPARC regulates the expression of collagen type I and transforming growth factor-beta1 in mesangial cells. Effects of 5-aza-2'-deoxycytidine on matrix metalloproteinase expression and pancreatic cancer cell invasiveness Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands The expression of the secreted protein acidic and rich in cysteine (SPARC) is associated with the neoplastic progression of human melanoma. SPARC, a matricellular glycoprotein with important biological functions SPARC, a matricellular protein that functions in cellular differentiation and tissue response to injury NK4, a four-kringle antagonist of HGF, inhibits spreading and invasion of human pancreatic cancer cells Overexpression of S100A4 in pancreatic ductal adenocarcinomas is associated with poor differentiation and DNA hypomethylation. Early detection of pancreatic carcinoma The fundamental role of epigenetic events in cancer Aberrant methylation of CpG islands in intraductal papillary mucinous neoplasms of the pancreas. Aberrant CpG island methylation in cancer cell lines arises in the primary cancers from which they were derived. Regulation of angiogenesis by SPARC and angiostatin: implications for tumor cell biology Enhanced growth of tumors in SPARC null mice is associated with changes in the ECM. Osteonectin/SPARC is overexpressed in human hepatocellular carcinoma SPARC regulates cell cycle progression in mesangial cells via its inhibition of IGF-dependent signaling The Ca2(+)-binding glycoprotein SPARC modulates cell cycle progression in bovine aortic endothelial cells Transcriptional upregulation of SPARC, in response to c-Jun overexpression, contributes to increased motility and invasion of MCF7 breast cancer cells Distribution of SPARC in normal and neoplastic human tissue Differential effects of SPARC and cationic SPARC peptides on DNA synthesis by endothelial cells and fibroblasts Can we screen high-risk individuals to detect early pancreatic carcinoma?
author name string	wds:Q73767192-5FD5E3FE-6D83-4805-990F-AB4DABC89D26 wds:Q73767192-FFFACC92-A9D3-4B8D-8144-E95B4E5BDC31
author name string	Norihiro Sato Gloria H Su
rdfs:label	SPARC/osteonectin is a frequent target for aberrant methylation in pancreatic adenocarcinoma and a mediator of tumor-stromal interactions (en) SPARC/osteonectin is a frequent target for aberrant methylation in pancreatic adenocarcinoma and a mediator of tumor-stromal interactions (nl)
skos:prefLabel	SPARC/osteonectin is a frequent target for aberrant methylation in pancreatic adenocarcinoma and a mediator of tumor-stromal interactions (en) SPARC/osteonectin is a frequent target for aberrant methylation in pancreatic adenocarcinoma and a mediator of tumor-stromal interactions (nl)
name	SPARC/osteonectin is a frequent target for aberrant methylation in pancreatic adenocarcinoma and a mediator of tumor-stromal interactions (en) SPARC/osteonectin is a frequent target for aberrant methylation in pancreatic adenocarcinoma and a mediator of tumor-stromal interactions (nl)
author	wds:Q73767192-35AE5D72-FF4C-4731-88F0-7D04793DA342 wds:Q73767192-6E5C863C-3520-4729-85F5-B836AB828969 wds:Q73767192-74A12243-DE67-4A2E-B809-A8465304FC81 wds:Q73767192-A1D0A0D2-1FBF-4C1C-B0B9-A8363CD5BFC4 wds:Q73767192-E052A4E9-6EB7-4D1E-BD96-D97BA5A5A708 wds:Q73767192-F4843BAA-654E-4603-AD49-1D724E610918
author	Ralph H. Hruban Michael Goggins Noriyoshi Fukushima Hiroyuki Matsubayashi Jens Koopmann Naoki Maehara
title	wds:Q73767192-5E639A7D-473C-4110-9CAA-F52541DFF694
title	SPARC/osteonectin is a frequent target for aberrant methylation in pancreatic adenocarcinoma and a mediator of tumor-stromal interactions (en)
page(s)	wds:Q73767192-1FDAAD70-0A49-4075-8E36-AA320FA5E2A9
page(s)	5021-5030
instance of	wds:Q73767192-C653BB9D-9F35-4B41-9664-F89908296C3B
instance of	scholarly article
main subject	wds:Q73767192-CAD3EA43-7D0D-4E65-B4B9-B67BDFA28507
main subject	pancreatic adenocarcinoma
PubMed ID	wds:Q73767192-9F43A920-BD99-4792-AB0B-E9FEEC25356A
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/12902985
PubMed ID	12902985
published in	wds:Q73767192-C3593DE0-BD35-4C83-A33F-4AC3E97C17E2
published in	Oncogene
issue	wds:Q73767192-04DAA2B3-8952-49A1-B846-6EAB5A7728E1
volume	wds:Q73767192-3FAAB29A-0FE8-4E43-8E34-E37627EFEA48
issue	32
volume	22
DOI	wds:Q73767192-469D13E5-B30C-42C4-926F-DFAC3C70B4B8
DOI	http://dx.doi.org/10.1038/SJ.ONC.1206807
DOI	10.1038/SJ.ONC.1206807
Dimensions Publication ID	wds:Q73767192-246F390B-420F-49A2-B268-EF2985220C5F
Dimensions Publication ID	1041598823

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