About: Heterodimeric phosphoinositide 3-kinase consisting of p85 and p110beta is synergistically activated by the betagamma subunits of G proteins and phosphotyrosyl peptide

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About: Heterodimeric phosphoinositide 3-kinase consisting of p85 and p110beta is synergistically activated by the betagamma subunits of G proteins and phosphotyrosyl peptide Goto Sponge NotDistinct Permalink

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scientific article published on 01 September 1997

Attributes	Values
rdf:type	Item
description	wetenschappelijk artikel (nl) наукова стаття, опублікована у вересні 1997 (uk) im September 1997 veröffentlichter wissenschaftlicher Artikel (de) artículu científicu espublizáu en setiembre de 1997 (ast) scientific article published on 01 September 1997 (en)
publication date	wds:Q73717928-E35111CF-065A-4644-BDCB-9227741A0C57
publication date	1997-09-01 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q73717928-E5495ADE-29C6-4C5C-ABCD-43FB2EA63092
language of work or name	English
author name string	wds:Q73717928-01993386-6825-4B4B-A91F-E68B6F54ACF0 wds:Q73717928-01FC1C8C-38CF-48C6-95E2-6DE456D48FA5 wds:Q73717928-52C6DFC0-B28E-4398-9387-9CCF2BF67940 wds:Q73717928-79BF743D-96A4-4EF8-9CA2-F0C87BF765A7 wds:Q73717928-A0CE79B3-BABA-42E4-A662-624C844E7188 wds:Q73717928-E6A0745F-C7DC-4285-B976-9D0E0FF23471 wds:Q73717928-F92DB7BE-7E23-4901-8C57-B4C13581B9B3 wds:Q73717928-FB9C5786-F6CF-4271-B867-AC2D3B527265
author name string	T Yamamoto T Okada Y Fukui S Hoshino M Ui T Katada H Kurosu O Hazeki
rdfs:label	Heterodimeric phosphoinositide 3-kinase consisting of p85 and p110beta is synergistically activated by the betagamma subunits of G proteins and phosphotyrosyl peptide (en) Heterodimeric phosphoinositide 3-kinase consisting of p85 and p110beta is synergistically activated by the betagamma subunits of G proteins and phosphotyrosyl peptide (nl)
skos:prefLabel	Heterodimeric phosphoinositide 3-kinase consisting of p85 and p110beta is synergistically activated by the betagamma subunits of G proteins and phosphotyrosyl peptide (en) Heterodimeric phosphoinositide 3-kinase consisting of p85 and p110beta is synergistically activated by the betagamma subunits of G proteins and phosphotyrosyl peptide (nl)
name	Heterodimeric phosphoinositide 3-kinase consisting of p85 and p110beta is synergistically activated by the betagamma subunits of G proteins and phosphotyrosyl peptide (en) Heterodimeric phosphoinositide 3-kinase consisting of p85 and p110beta is synergistically activated by the betagamma subunits of G proteins and phosphotyrosyl peptide (nl)
author	wds:Q73717928-8D6ABA92-2201-4C8C-801E-E59AAF40F2C6
author	Tomohiko Maehama
title	wds:Q73717928-2D670BDB-B2C0-413B-93D0-6E51A546F207
title	Heterodimeric phosphoinositide 3-kinase consisting of p85 and p110beta is synergistically activated by the betagamma subunits of G proteins and phosphotyrosyl peptide (en)
page(s)	wds:Q73717928-F3D9BA6D-B41A-4C03-A79E-B8E9E5C0AFE5
page(s)	24252-24256
instance of	wds:Q73717928-77321078-39CF-4039-B010-FC2D5F3BF154
instance of	scholarly article
PubMed ID	wds:Q73717928-6D871652-6F53-46B8-84BF-874074B94F98
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/9305878
PubMed ID	9305878
published in	wds:Q73717928-AE7A1DB7-F9B5-49E9-8D4F-B62554DD4209
published in	Journal of Biological Chemistry
issue	wds:Q73717928-E4731E6A-A58D-4D62-8AC0-4327BDA281D4
volume	wds:Q73717928-A53E8ADE-6574-4846-898E-53D600560020
issue	39
volume	272
DOI	wds:Q73717928-CADC96C8-5425-46EE-BE14-3A96D182AACB
DOI	http://dx.doi.org/10.1074/JBC.272.39.24252
DOI	10.1074/JBC.272.39.24252
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q73717928
is cites work of	Ligand-directed signalling at beta-adrenoceptors Roles of G beta gamma in membrane recruitment and activation of p110 gamma/p101 phosphoinositide 3-kinase gamma The emerging mechanisms of isoform-specific PI3K signalling The phosphoinositide 3-kinase pathway in human cancer: genetic alterations and therapeutic implications. PI3K in cancer: divergent roles of isoforms, modes of activation and therapeutic targeting Cell surface receptors activate p21-activated kinase 1 via multiple Ras and PI3-kinase-dependent pathways Mechanisms by which cAMP increases bile acid secretion in rat liver and canalicular membrane vesicles The long-term consequences of intra-uterine protein malnutrition for glucose metabolism. The p110beta isoform of phosphoinositide 3-kinase signals downstream of G protein-coupled receptors and is functionally redundant with p110gamma. Evidence for functional redundancy of class IA PI3K isoforms in insulin signalling. Comparison of the kinetic properties of the lipid- and protein-kinase activities of the p110alpha and p110beta catalytic subunits of class-Ia phosphoinositide 3-kinases A specific function for phosphatidylinositol 3-kinase alpha (p85alpha-p110alpha) in cell survival and for phosphatidylinositol 3-kinase beta (p85alpha-p110beta) in de novo DNA synthesis of human colon carcinoma cells Phosphoinositide 3-kinase β mediates microvascular endothelial repair of thrombotic microangiopathy The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate Chemokines and T lymphocytes: more than an attraction. Ca(2+)-evoked serotonin secretion by parafollicular cells: roles in signal transduction of phosphatidylinositol 3'-kinase, and the gamma and zeta isoforms of protein kinase C. Polycystin-1 induces resistance to apoptosis through the phosphatidylinositol 3-kinase/Akt signaling pathway. Targeting PI3K signalling in cancer: opportunities, challenges and limitations PTEN-deficient cancers depend on PIK3CB. Critical role for the p110alpha phosphoinositide-3-OH kinase in growth and metabolic regulation Ras is an indispensable coregulator of the class IB phosphoinositide 3-kinase p87/p110gamma RAS and RHO families of GTPases directly regulate distinct phosphoinositide 3-kinase isoforms Chemokines: understanding their role in T-lymphocyte biology. Long-term potentiation in dentate gyrus of the rat is inhibited by the phosphoinositide 3–kinase inhibitor, wortmannin Protein-tyrosine-phosphatase-mediated epidermal growth factor (EGF) receptor transinactivation and EGF receptor-independent stimulation of mitogen-activated protein kinase by bradykinin in A431 cells Alpha-thrombin-mediated phosphatidylinositol 3-kinase activation through release of Gbetagamma dimers from Galphaq and Galphai2. Activated Gαq Inhibits p110α Phosphatidylinositol 3-Kinase and Akt Therapeutic potential of phosphoinositide 3-kinase inhibitors. PI3K promotes voltage-dependent calcium channel trafficking to the plasma membrane Specific role for p85/p110beta in GTP-binding-protein-mediated activation of Akt. Activation of PI 3-kinase by G protein betagamma subunits Phosphoinositides: tiny lipids with giant impact on cell regulation Dystrophin glycoprotein complex-associated Gbetagamma subunits activate phosphatidylinositol-3-kinase/Akt signaling in skeletal muscle in a laminin-dependent manner Signaling specificity by Ras family GTPases is determined by the full spectrum of effectors they regulate Therapeutic strategies in fragile X syndrome: dysregulated mGluR signaling and beyond Neuron-specific regulation of class I PI3K catalytic subunits and their dysfunction in brain disorders Signaling from G-protein-coupled receptors to mitogen-activated protein (MAP)-kinase cascades Calcium receptor-induced serotonin secretion by parafollicular cells: role of phosphatidylinositol 3-kinase-dependent signal transduction pathways. Selective role of PI3K delta in neutrophil inflammatory responses Gastric inhibitory peptide controls adipose insulin sensitivity via activation of cAMP-response element-binding protein and p110β isoform of phosphatidylinositol 3-kinase Protein kinase A-dependent and -independent signaling pathways contribute to cyclic AMP-stimulated proliferation. Heterotrimeric G-protein betagamma-dimers in growth and differentiation Characterization and targeting of phosphatidylinositol-3 kinase (PI3K) and mammalian target of rapamycin (mTOR) in renal cell cancer A specific role of phosphatidylinositol 3-kinase gamma. A regulation of autonomic Ca(2)+ oscillations in cardiac cells Regulation of MAP kinase activity by peptide receptor signalling pathway: paradigms of multiplicity Multi-level targeting of the phosphatidylinositol-3-kinase pathway in non-small cell lung cancer cells A function for phosphatidylinositol 3-kinase beta (p85alpha-p110beta) in fibroblasts during mitogenesis: requirement for insulin- and lysophosphatidic acid-mediated signal transduction

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